!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Tretinoin
!smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
!drugbank_id	DB00755
!pubchem_cid	444795
!cell_type	NA
!organism	mouse
!end_metadata
RPS19	0.219141
RPL13	0.203201
SFTPC	0.161891
AGER	0.142943
WDR92	0.141433
S100A6	0.141410
RPS2	0.138574
ENG	-0.132938
TUBA1C	-0.130361
HOPX	0.124340
EEF1A1	-0.123930
WFDC2	0.115025
LGALS1	-0.112211
RABAC1	0.112105
RPL8	0.110803
SCGB1A1	0.109166
CA2	-0.106078
NPC2	0.101920
TUBA1A	-0.101539
CTSD	0.094550
GSTO1	-0.089576
FSCN1	-0.088661
H19	-0.086730
CD74	-0.083306
RPLP0	0.083083
JUND	-0.080073
RNF10	-0.080018
B2M	-0.079220
YBX1	0.078820
MDK	-0.077720
YWHAZ	-0.077105
PPIA	-0.076424
ADH1C	-0.076046
CCNB2	-0.074780
RAC1	-0.074098
COL4A2	-0.073983
RPS10	0.072422
RPS5	0.072330
COL1A1	-0.070856
ARF1	0.069739
CHCHD10	0.068282
RPL5	0.067576
NREP	-0.064960
DLK1	-0.064613
MFGE8	0.064263
ACAA2	0.063778
PABPC1	-0.061982
BPGM	-0.061634
HTRA1	-0.058055
COL5A2	-0.057824
ACTG2	-0.057557
NAPSA	0.057245
ACTC1	-0.057202
TRIM28	-0.056756
SLC34A2	0.056084
EMP1	0.055699
POLR2M	-0.055594
INMT	0.055228
NDUFB5	0.054793
RPL19	-0.054349
TMOD3	0.052758
MFAP2	-0.052757
RPL37A	0.051316
ANXA2	-0.051273
FTH1	0.050927
ARHGDIA	-0.050626
GPX3	0.050513
MYLK	-0.050420
ARGLU1	0.050171
MARCKSL1	-0.049818
TMEM176B	0.049798
MEST	-0.049615
ANXA6	-0.049541
KRT4	-0.049170
MFAP4	-0.048961
TMEM165	0.048942
CSRP1	-0.048776
RPS11	0.048267
RPL18	0.048245
COL1A2	-0.047904
APOE	0.047770
NCL	-0.047037
SOD1	0.046778
HSP90AB1	-0.046678
ACTA2	-0.046322
RBP1	0.045724
CAPNS1	-0.045654
NOP10	0.045434
PLK3	-0.045273
ALAS2	-0.045148
RPS23	-0.044872
ATOX1	0.044480
CTNNB1	0.044298
BTF3	0.044271
ACTA1	-0.044033
SCD	0.043691
YPEL3	0.043124
S100A8	0.042948
TMEM176A	0.042931
MYH9	-0.042909
LAPTM4A	0.042786
TUBA1B	-0.042397
LMO7	0.042268
STMN1	-0.042184
H2AFX	-0.042012
SARAF	0.041984
HMGN1	0.041379
C12orf57	0.041261
H1F0	-0.040359
MAGED1	-0.039073
SFT2D1	0.039052
SPARC	-0.038959
NDUFA7	0.037641
RPS3	0.037509
CLIC3	0.037300
CNN3	-0.037132
GNG5	0.037069
UBL3	0.036899
PSMA3	0.036571
PSMD5	0.036217
CHI3L1	0.035995
PLP2	0.035927
CYBA	0.035346
UBE2L3	0.035342
EIF3G	0.035310
PRDX2	-0.035255
GSN	0.035229
EIF2S3	0.034939
MGP	0.034834
IGFBP6	0.034549
CD81	-0.034444
UGDH	-0.034425
EGLN2	0.034207
SEPT7	0.033896
ANXA5	0.033878
C5	0.033689
CMTM8	0.033623
CLIC4	0.033553
BRI3	0.033472
CCND3	-0.033466
CES1	0.033365
NOTCH3	-0.033334
MAF1	0.033094
CHD4	0.033051
CEBPD	0.032849
FAM46C	-0.032305
UBC	-0.032212
SSRP1	-0.031804
PHLDA1	-0.031432
RPS15A	0.031252
SPTAN1	-0.030930
ATP5O	-0.030896
RXRB	0.030689
CD9	0.030655
CORO1C	-0.030644
TPT1	0.030634
ITGB1	-0.030397
PRKAR1A	-0.030077
PTPRF	0.030042
PSCA	-0.029948
GAPDH	-0.029943
MYL12A	-0.029715
ATP5A1	-0.029699
CCT7	0.029656
CDC20	-0.029583
RBM3	-0.029388
COL6A1	0.029358
PLEC	-0.029160
HSD17B4	0.029090
MYADM	-0.029008
RAMP2	-0.028929
PARK7	0.028925
CTSS	0.028921
TMED7	0.028827
NPNT	-0.028800
TRAM1	-0.028739
ALDOA	-0.028689
PPP4C	0.028549
SYPL1	0.028521
COL3A1	-0.028420
H2AFZ	-0.028405
BRK1	-0.028074
STX5	0.027856
NDUFS2	-0.027830
PPP3R1	0.027828
CYP4B1	0.027576
FIGF	-0.027323
LTBP4	-0.027238
ATP6V0C	-0.027186
UNC50	0.027166
MYH11	-0.027162
PSMD1	-0.027133
LLGL2	0.027022
SEC11A	0.026897
FKBP1A	-0.026894
PRDX1	-0.026861
RAD21	-0.026803
LTBP2	-0.026796
RIN2	0.026746
TKT	-0.026731
FSTL1	-0.026652
ELAVL1	-0.026628
TGFBI	-0.026617
PPP2R1A	-0.026606
JTB	0.026597
PTOV1	0.026516
PTRF	-0.026300
KIF22	-0.026254
SERP1	0.026241
IGFBP2	-0.026214
MYL7	-0.026097
PFKL	0.026089
DYNLL1	0.025918
YIPF3	0.025685
APLP2	-0.025509
FAM101B	0.025497
EIF3K	0.025496
LATS2	0.025313
F2RL1	0.025313
UBE2R2	0.025175
PLTP	0.025156
HLA-A	-0.025108
ACAA1	0.025080
COPA	-0.025078
RPS12	0.025011
SELENBP1	0.024935
DHRS1	-0.024826
GORASP2	0.024778
RPL7	-0.024739
NDUFA11	0.024692
SNX4	0.024650
DNAJA1	0.024632
CDK1	-0.024632
COX7A2L	0.024473
XBP1	0.024430
ANXA3	0.024336
ATPIF1	0.024269
SHFM1	0.024199
GNAI2	-0.024139
IMP3	0.024093
TMEM259	0.024060
GNB2L1	0.023960
NELFA	0.023950
PTP4A1	0.023827
TCF21	0.023827
HPCAL1	0.023823
HLA-DQA1	-0.023821
SEC61B	0.023720
IER3	0.023710
MATN4	0.023645
SURF4	-0.023630
EIF4A2	0.023484
PRC1	-0.023450
TNNC1	-0.023426
NAPA	0.023345
ZMYND11	0.023183
TGFB1I1	-0.023025
ARL2BP	0.022929
EPB41	-0.022918
EIF1B	0.022814
EPN2	-0.022784
OSTF1	0.022736
FAM134B	0.022702
TAGLN	0.022486
KRTCAP2	0.022459
H2AFV	-0.022449
ATP1B3	0.022428
PDIA3	-0.022410
SRRT	-0.022394
PGM1	0.022361
SRSF6	0.022280
RPS17	0.022273
RBM4B	-0.022231
TMED4	0.022203
KDELR1	-0.022115
RNF141	0.022105
LIMCH1	0.022096
CLK1	0.021995
BANF1	-0.021960
UQCRC2	0.021900
RNF11	0.021642
PGRMC1	0.021628
SOX18	-0.021463
ANAPC11	0.021417
FHL1	-0.021394
NFIB	-0.021379
SPARCL1	-0.021333
PAPSS1	-0.021197
CS	-0.021177
CTSH	0.021075
FZD2	0.021056
COX17	0.021012
YWHAG	0.021000
EIF3J	0.020953
SDHB	0.020866
LDHA	-0.020862
GSK3A	-0.020850
CYP2F1	0.020836
HNRNPH1	-0.020831
CNN2	-0.020816
CBFB	0.020763
RAN	-0.020743
SUPT6H	-0.020664
RPL10A	0.020577
GPR12	0.020515
TSPO	0.020514
NCKAP1	-0.020492
CDC42EP4	-0.020488
SPAG7	-0.020481
PCBP1	-0.020480
CRTAP	-0.020392
GJA1	0.020373
SF3B5	0.020360
HP	0.020354
RBM42	-0.020320
SPG21	0.020279
RPS7	0.020267
TIE1	-0.020141
HSPG2	-0.020122
NPC1	0.020110
TMEM109	-0.020032
H1FX	-0.019967
DPT	-0.019843
SMAD4	0.019842
RGCC	0.019810
VPS28	0.019800
SRPR	0.019778
ISG15	-0.019720
TIMM23	0.019720
SQLE	-0.019671
THRAP3	-0.019645
DYNC1H1	-0.019567
PTPRU	0.019528
KLF6	0.019462
STXBP1	-0.019425
TOP1	0.019387
CD34	-0.019311
SLC4A1	-0.019297
RCAN1	-0.019242
MAGED2	-0.019241
VASP	-0.019214
ATP6V0B	0.019182
PSMD7	-0.019158
CSDE1	0.019109
FGFR2	0.019060
HNRNPK	0.019011
ADARB1	0.018983
SLC25A39	-0.018927
KIF23	-0.018919
ACLY	-0.018912
ROMO1	0.018836
ANXA11	-0.018833
FNTA	0.018833
MAPK3	-0.018818
POLR2A	-0.018816
HNRNPM	-0.018791
RALBP1	0.018772
PSAP	0.018709
RNF26	-0.018705
CKB	-0.018677
TXNDC5	-0.018668
RECK	-0.018615
CD93	-0.018602
TXN	0.018577
WDR45	0.018557
SDHD	0.018543
FAM195B	0.018496
BSG	0.018488
VPS35	0.018425
COLGALT1	0.018423
GLRX3	0.018403
FBLN2	-0.018386
VAMP8	0.018324
RERE	-0.018299
POMP	0.018138
VMP1	0.018131
CTNND1	0.018088
COX6A2	0.018031
RPL6	0.018027
GLTP	-0.018000
RRAGC	0.017997
LYPLA2	0.017928
IER2	0.017885
LSM4	0.017881
SUN2	-0.017822
SRSF2	-0.017814
MDFIC	0.017777
CAPZB	0.017774
PSMA6	0.017763
IGF2R	-0.017720
RPS26	0.017703
EIF2AK1	-0.017686
IGF2	-0.017560
CDKN2C	-0.017554
UQCRQ	0.017507
MYL1	-0.017493
CLPTM1L	0.017460
PCNA	-0.017453
IRF1	-0.017441
NUCB1	-0.017411
APP	0.017406
LMO4	0.017390
UQCR10	0.017381
MANF	0.017372
YIF1A	0.017367
TUBB3	0.017331
PRCC	-0.017323
PRDX5	0.017205
RPL7A	-0.017201
HSPA5	0.017166
RPL28	-0.017121
FERMT2	-0.017103
DPF2	-0.017059
TPGS2	0.017049
SERPINB9	0.017048
SLC35B1	0.016868
ARHGAP1	-0.016863
SAR1A	-0.016760
CCNA2	-0.016756
APCDD1	-0.016727
TOMM7	-0.016666
SEMA4F	0.016557
ANAPC5	-0.016543
SERPINB6	-0.016493
MYBPC3	-0.016481
STX4	0.016445
ATP6V0D1	-0.016413
ELOVL5	-0.016380
ADIPOR2	-0.016300
TALDO1	-0.016262
H6PD	-0.016249
NUDT3	-0.016230
AP1S1	-0.016227
IRX3	0.016215
TRADD	0.016195
AP2M1	-0.016190
DMTN	-0.016119
CKS2	-0.016115
C20orf24	0.015974
C14orf2	0.015966
EPN1	-0.015961
EIF4A3	-0.015933
BAK1	-0.015907
FDX1	0.015817
GPS1	0.015794
DDAH2	-0.015770
NDFIP1	0.015746
PRDX4	-0.015698
FKBP8	0.015692
TUBB2A	-0.015683
INPP5K	0.015646
MKI67	-0.015618
MPEG1	0.015606
TUBB6	-0.015593
KIF20A	-0.015544
METTL9	0.015512
CNN1	-0.015496
PSAT1	-0.015456
SH3BGRL	0.015447
MLLT3	0.015446
PTTG1IP	0.015422
APOA1BP	0.015401
KRT6B	-0.015374
SEC61G	-0.015366
COX7A2	0.015365
UQCRB	0.015336
LMNA	-0.015328
DXO	-0.015275
ANLN	-0.015270
MCL1	0.015247
SLC39A8	0.015245
PPDPF	0.015244
PPP1R15B	0.015207
C1orf174	0.015195
MRPL52	0.015193
SERPING1	-0.015187
NUP107	0.015177
TPP1	0.015169
ANXA4	0.015166
RPL3	-0.015156
SMPDL3A	0.015147
HDGF	-0.015083
STOML2	0.015050
CHUK	0.015044
TACSTD2	0.015037
HNRNPL	-0.015034
PLA2G1B	-0.015026
SEP15	0.015022
MATR3	0.014989
TMEM159	0.014937
NRAS	0.014863
TOP2A	-0.014860
BIRC5	-0.014840
LIMS1	0.014818
EZH2	-0.014809
TMEM123	0.014807
IGF2BP2	0.014775
CLDN3	0.014753
CLK2	0.014742
CEBPA	0.014717