!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Morphine
!smiles	CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
!drugbank_id	DB00295
!pubchem_cid	5288826
!cell_type	No Data
!organism	mouse
!end_metadata
TTR	-0.116426
PTGDS	-0.106957
ADORA2A	-0.062678
ALDH1A2	-0.061053
ACTA2	0.057902
GPR88	-0.056043
SPP1	-0.055538
MAG	0.053772
MOBP	0.050957
C5orf28	0.050471
PENK	-0.048849
FBLN5	0.047646
GALNTL6	0.045838
TAC1	-0.045225
SEMA3A	-0.044899
SLC6A13	-0.044560
TSHZ2	-0.039008
MURC	0.038284
SLC6A3	-0.037628
RORA	0.037117
DCN	-0.036696
CBLN1	-0.035375
TMTC3	0.034923
SCN4B	0.034810
SMAGP	-0.034554
CDC6	0.034461
PVALB	-0.033850
LENG8	-0.033849
RXFP1	-0.033596
EFEMP1	-0.032913
FAM107A	0.032776
ALAS2	0.032561
KCTD16	0.032236
SLC18A2	0.032076
NTF3	-0.031714
CYP26B1	-0.031661
RSPO2	-0.031324
NTNG1	0.031209
KMT2C	0.031131
ATP5L	0.030980
TAF1A	-0.030278
RARB	-0.030133
CPNE9	0.030040
POP1	0.029684
DRD2	-0.029480
MYH11	0.029479
PSME2	0.029437
MEIS2	-0.029352
PBX3	-0.029313
SLC6A4	0.029062
NR4A2	-0.029010
COLEC12	-0.028967
IL22	0.028902
PCLO	0.028815
TTC14	-0.028695
THSD7A	0.028638
ATXN1	0.028575
NEXN	0.028376
UNC80	0.028233
TYK2	-0.028217
PTPN3	0.028209
NPFF	0.028158
KLHL36	0.028096
LRP1B	0.027914
SLITRK6	0.027900
SFRP4	-0.027896
ESRRG	-0.027727
IMP3	0.027664
RYR2	0.027644
NAF1	-0.027586
KITLG	0.027562
CLIC6	-0.027551
TMEM150A	-0.027344
TAF5	0.027318
TENM1	0.027307
SLC22A6	-0.027253
SLC13A3	-0.027106
MYCBP2	0.027030
TCF7L2	0.026967
PLP1	0.026870
GAREM	0.026805
THBD	-0.026739
HRH3	0.026623
PPP1R1B	-0.026603
RGS11	-0.026496
ISLR	-0.026323
ETAA1	-0.026283
WBSCR17	0.026244
ATP4A	0.026193
SLC6A12	-0.026164
CDH6	0.026077
SLC19A2	0.026041
SLC22A8	-0.026027
FMOD	-0.026023
ZGPAT	-0.026012
LRRC10B	0.026009
LECT1	-0.025894
CREBRF	0.025841
SAP25	-0.025797
CDH12	0.025794
PVRL1	0.025757
CHKB	0.025745
TNFAIP8L1	-0.025604
ZNF213	0.025419
GPX6	0.025354
IDO2	0.025290
SLC7A11	-0.025205
LYSMD2	0.025086
BMF	0.025011
C1orf65	0.024831
SYNE1	0.024798
ST8SIA2	-0.024741
FILIP1	0.024582
PCBD1	0.024534
BIRC6	0.024515
LHX9	0.024488
DDX3Y	-0.024476
TRA2A	-0.024469
CABP7	0.024412
CXorf64	0.024403
MAVS	-0.024392
VPS13D	0.024307
C8orf33	0.024279
SMIM3	0.024277
OGN	-0.024264
PAMR1	0.024233
HECTD4	0.024224
FAM19A1	0.024203
NRROS	0.024177
H19	-0.024163
KCNE4	0.024087
FKBP1B	0.023970
MYLIP	-0.023960
LY9	0.023937
TMEM256	0.023920
PLLP	0.023825
SOX14	0.023763
SLC10A4	0.023739
DKKL1	-0.023687
ZBP1	0.023684
ARHGAP32	0.023675
NOV	-0.023658
ZNF579	-0.023598
ATG10	0.023524
FRY	0.023511
ASAH2	0.023508
GHRHR	0.023479
DUSP4	-0.023449
RASD2	0.023420
OPHN1	-0.023346
LRRTM3	-0.023323
ALDH3B1	0.023264
PEG10	-0.023231
SLCO2A1	0.023215
FAT1	0.023198
B3GALT5	0.023189
LRRC7	0.023141
ADH1C	-0.023122
NFE2L2	0.023085
SERPINB9	0.023005
TMPRSS4	-0.022966
DSC3	0.022919
BCL2L12	-0.022904
RBP1	-0.022892
RASD1	0.022866
KDM4D	0.022860
ZFP57	-0.022852
SLC22A2	-0.022692
KCNK18	-0.022624
CD63	0.022588
TACR3	-0.022585
CLDN1	0.022552
SERPING1	-0.022547
MMP7	0.022546
AGXT	0.022461
LYAR	0.022411
CRTC2	-0.022395
VIPR2	0.022375
EOGT	-0.022239
CNTN5	0.022202
CHD2	0.022200
TSHZ3	-0.022191
HERC1	0.022177
ANKRD55	-0.022177
HIST1H4F	-0.022154
MOS	-0.022138
SHE	0.022135
LIMA1	0.022126
METTL4	-0.022097
ADARB1	0.022094
ZCCHC3	0.022067
DNMT3L	0.021989
RORB	0.021965
LAYN	0.021957
KCNE1L	-0.021946
SMPDL3B	0.021938
SMARCA5	0.021919
ZCCHC12	-0.021905
MAPK11	-0.021903
PURG	0.021902
HOXD9	0.021876
GEM	-0.021851
FA2H	0.021830
PCNX	0.021799
CIART	0.021792
KIAA1109	0.021761
FRZB	0.021759
SESN2	0.021712
CHTF18	-0.021687
DERA	0.021687
CSF2RA	-0.021686
DSG1	0.021677
HTRA1	0.021671
KIAA1244	0.021661
ZCCHC16	0.021631
MKX	0.021590
C2CD4A	0.021575
TNFRSF1B	-0.021567
SEBOX	0.021559
LDLR	-0.021535
VAT1L	-0.021529
AMOT	0.021524
SYT6	0.021502
BSN	0.021498
VANGL1	0.021484
DYNC1H1	0.021339
KNDC1	0.021338
SLC9A5	-0.021316
LUM	-0.021311
ZNF668	-0.021309
A4GALT	0.021305
SLC2A12	0.021264
DMPK	-0.021256
CCL19	-0.021254
COL1A2	-0.021228
PGF	-0.021210
RAB34	-0.021201
SLC8A1	0.021187
SRD5A3	0.021177
SLC13A4	-0.021108
TGDS	0.021096
IGFALS	0.021082
STXBP6	0.021068
KIAA0040	0.021043
COMMD2	0.021041
STRC	0.021025
LRRC16B	-0.020981
DUSP16	0.020972
B3GNT2	0.020969
ANK3	0.020891
MYEOV2	0.020870
PCDH7	0.020867
MBD6	-0.020858
C2CD4B	0.020842
PEAK1	0.020828
ARL11	0.020825
CPN1	0.020821
MID1	-0.020820
ABHD14B	-0.020788
JTB	0.020753
DHRS7C	0.020747
FBLN1	-0.020740
ST6GALNAC1	0.020723
NAA40	-0.020711
SMYD5	-0.020706
HABP2	0.020698
PCDH20	0.020689
SIX2	0.020678
UQCRFS1	0.020651
TGIF2	-0.020650
FAT4	0.020638
PIK3CG	-0.020634
SYNPO2	0.020618
GFAP	-0.020602
FAT3	0.020592
GAL3ST3	0.020555
PRKCH	0.020545
TGFB3	0.020534
LRP1	0.020526
SLC22A13	0.020508
RBM12B	-0.020507
DIO1	0.020490
RHBG	0.020470
ATF1	-0.020456
C19orf54	0.020451
MRPL50	0.020447
DDIT4L	-0.020438
ZSWIM5	0.020427
MYBPHL	0.020419
ACOT11	0.020411
GOLM1	0.020324
KLHDC4	-0.020320
HERC2	0.020303
HCST	0.020272
EMX2	0.020244
IQSEC3	0.020238
THBS3	-0.020204
PKNOX2	-0.020178
NKX2-8	0.020172
CYTL1	0.020166
NKX2-2	-0.020163
TWISTNB	0.020160
TCF7L1	0.020156
CBLN4	-0.020152
HPGDS	0.020150
PDCD10	0.020131
DSE	-0.020128
SLITRK3	0.020114
TIA1	-0.020110
C3AR1	-0.020104
BHLHA15	0.020051
CARNS1	0.020038
TIGD5	0.020024
CRABP1	-0.020010
OR6B2	0.020005
PCDH19	0.019987
HSPA5	-0.019941
SLC4A1	0.019897
SHISA9	0.019890
DERL2	-0.019869
SLC16A11	-0.019865
TCEA3	0.019840
DNAI2	-0.019830
C21orf91	-0.019814
PIK3C2A	-0.019787
LIN52	0.019785
PLXNA4	0.019767
ZFPM1	0.019751
SLC6A9	-0.019737
ISYNA1	-0.019726
KRT8	-0.019717
MRC1	-0.019715
CCNT2	-0.019714
SCIN	-0.019700
ISL1	-0.019675
TBX2	-0.019659
OSR1	-0.019650
NRN1	0.019627
KCNH6	0.019566
OMG	0.019553
SPIB	0.019552
FAM181A	-0.019545
GRM2	-0.019544
HDC	0.019540
SELV	0.019530
CELSR2	0.019517
PLEKHF1	0.019506
FLNA	-0.019474
FEZF2	-0.019443
TMC4	-0.019441
CACNA1E	0.019435
GJB2	-0.019435
UGT8	0.019434
MOG	0.019430
GTDC1	0.019422
RIN1	-0.019415
VASN	0.019409
NXPH3	-0.019369
TMPO	-0.019352
FAM162B	0.019319
BAZ2B	0.019317
C1orf52	0.019296
LEF1	0.019276
C15orf59	0.019258
PGAP3	-0.019247
SGMS2	0.019234
SCLY	0.019233
TIMM21	-0.019227
KCNA4	0.019227
ARHGDIA	-0.019224
FADD	-0.019198
ANKRD24	-0.019188
MCM4	-0.019180
COL20A1	0.019151
MNX1	0.019141
DDX11	-0.019138
STK38	-0.019136
DTL	-0.019106
NEK3	-0.019094
SLC8A3	0.019083
ITGA8	0.019082
FAM211A	0.019058
ERICH1	0.019044
ZNF253	0.019035
KLHL15	0.019021
MEF2A	0.019014
SLC32A1	-0.019004
TMEM163	0.018985
NUP93	-0.018981
TENC1	-0.018968
MTFP1	0.018959
TMTC2	-0.018927
TLN2	0.018882
TNR	0.018833
FIGNL2	0.018831
GUCY1A2	0.018821
HARS2	-0.018818
EVC	-0.018811
P2RY1	-0.018795
ACTA1	-0.018783
MAGEL2	-0.018767
RANBP3L	-0.018766
KMT2D	0.018763
PCDH1	-0.018716
AZI2	0.018713
IMPDH2	-0.018707
DND1	0.018696
DNAJC15	0.018669
CPQ	0.018656
TNFRSF13C	-0.018655
ASH1L	0.018639
DISP1	-0.018628
ROBO2	0.018618
UBE2J2	0.018613
FADS6	0.018600
PLEKHB1	0.018552
HOXB9	-0.018541
NEFH	0.018534
GCSAM	0.018526
SLC25A33	0.018524
METTL8	0.018518
CLDN22	0.018507
ARMC9	-0.018495
NPY1R	-0.018484
BDKRB2	-0.018471
CARHSP1	-0.018461
TIFAB	0.018457
EPHA6	0.018447
OR8A1	0.018420
UFSP1	0.018389
MPHOSPH10	0.018388
OPRK1	0.018385
POU2F3	-0.018382
SYAP1	0.018361
AMOTL1	0.018350
VAV2	-0.018328
BRINP3	-0.018306
PLIN4	0.018300
SNED1	-0.018297
CHEK1	-0.018293
CSRP1	0.018282
GPR50	0.018270
XRCC1	-0.018251
C9orf173	-0.018250
HOXB3	-0.018228
ZNF366	-0.018177
FCF1	-0.018175
C2orf82	0.018170
USP31	0.018160
BCL2L15	0.018159
PBDC1	0.018157
TMEM2	0.018147
MPL	-0.018134
FLT3LG	-0.018131
FUT10	0.018124
F13A1	0.018122
RASGRP2	-0.018122
PITHD1	0.018114
SAFB2	-0.018097
C11orf16	0.018080
DPYD	0.018079
MRPL34	-0.018042
TMEM132D	0.018041
NPBWR1	0.018031
FUT11	-0.018028
OR2F1	0.018021
FAM131C	-0.017988
EMILIN1	-0.017983
MRPL22	0.017978
DLX5	-0.017965
RPL32	0.017956
KCNH5	0.017950
CCBE1	0.017947
IYD	0.017944
NAV3	0.017929
CPEB3	0.017924
LDB2	-0.017919
TUBA8	0.017911
FBXO36	0.017894
UBALD1	0.017889
MAP1A	0.017873
SYNJ1	0.017870
AEBP1	-0.017860
IDI1	-0.017829
C1orf189	-0.017821
HPS4	-0.017818
SMCR8	0.017817
GPR3	-0.017810
ZIC5	-0.017801
NCAPG2	-0.017796
PABPN1	-0.017796
MPO	0.017794
C2orf68	-0.017792
WNT6	-0.017771
RING1	-0.017764
NOA1	0.017761
PRRX1	-0.017749
ZNF414	-0.017747
SPTSSB	0.017728
PIAS3	0.017711