!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!gene	SIRT1
!cell	Skin
!perturbation	SIRT1 activator, SRT2104
!disease	Psoriasis - 250mg - 84 days
!end_metadata
PM20D1	0.083775
KRT79	0.081212
TCHH	-0.075611
CXCL8	-0.074696
UPK1A	0.071569
TCN1	-0.065171
HOXC10	-0.062330
GSTT2	0.061111
OR5P2	-0.060565
FADS1	0.057911
AADAC	-0.057715
KRT71	-0.056554
IGJ	0.056211
KRT25	-0.055717
PLIN1	-0.053843
PCTP	0.052133
THRSP	0.052016
CD207	-0.051704
LPL	-0.051066
G0S2	-0.050720
SPC25	0.050339
LOC642776	0.050330
TBCK	-0.049192
GAL	0.048841
PRR9	-0.048113
KRT31	-0.046578
UCA1	0.046574
CILP	-0.045970
GJB4	-0.045866
TMEM99	-0.044503
OR5P3	-0.044423
NLRP2	-0.044312
CYP4B1	-0.044187
C5orf27	0.044138
ZBTB16	-0.043652
POMK	-0.043649
MUC7	-0.043403
CHRNA9	0.042776
GZMB	0.042734
LEP	-0.042434
S100A12	-0.042274
TF	0.041933
IGKC	0.041914
FABP7	0.041805
AHRR	0.041678
GPR143	-0.041324
ACSBG1	0.040197
PGLYRP4	-0.039273
CARD18	-0.039142
HAO2	0.039099
LOC642236	-0.038443
SRPX	-0.038242
SELE	0.038069
PPP1R1B	-0.037874
FBP1	0.037500
EGFL6	-0.037333
PRR4	-0.037020
SPRR4	0.036541
KANSL1-AS1	-0.036323
AOX1	-0.036299
AWAT1	0.036228
CLIC3	-0.036170
HLA-DRB4	-0.036071
HMCN1	0.035888
GBP3	0.035249
HSD17B2	0.035039
LTF	-0.034972
MCU	-0.034895
PSORS1C2	-0.034554
PNLDC1	0.034455
CRAT	0.034402
LAMP3	-0.034162
PPFIA4	0.034119
IGLV2-23	0.034059
TUBB4A	-0.033835
CLMP	0.033798
GLDC	0.033759
SERPINB4	-0.033590
IGFL1	-0.033580
HYAL1	-0.033511
BTC	-0.032901
LINC00893	-0.032704
C2orf40	-0.032651
HLA-DQB2	-0.032640
HYAL4	0.032482
TUT1	0.032361
CDC7	0.032183
GEMIN5	-0.032143
FAM111B	-0.032063
LCE1E	0.031997
LINC00842	-0.031945
LOC150005	0.031929
HYMAI	0.031907
SOD3	-0.031881
TVP23C	0.031775
PAX8-AS1	-0.031750
SCGB2A1	-0.031624
TMPRSS11E	0.031448
FLRT2	-0.031301
FA2H	0.031257
PNPLA3	0.031250
GBP6	0.030984
TMEM117	-0.030960
KRT4	0.030942
PDXDC2P	-0.030891
KRT27	-0.030842
SNHG9	-0.030827
CHRDL1	0.030776
NDC80	0.030685
IL37	-0.030628
C11orf68	-0.030603
BRIX1	-0.030502
LINC00302	-0.030395
SLC27A2	0.030387
LCN2	-0.030251
IL7R	-0.030120
IL1B	-0.030117
TNIP3	0.030114
CEACAM6	-0.029920
PRIMA1	-0.029898
CCL21	0.029894
OCA2	-0.029637
TPRG1	-0.029614
LOC388820	0.029494
TRANK1	-0.029464
EDNRB	-0.029410
FKBP5	-0.029405
IGLV1-44	0.029334
HORMAD1	-0.029274
ACSM3	0.029253
SERPINB3	-0.029135
FLJ41757	-0.029005
FADS2	0.028986
PTGDS	-0.028948
KHDRBS3	-0.028929
SCGB1D2	-0.028893
ACTC1	-0.028880
SF3B4	-0.028793
PLIN4	-0.028764
IL34	-0.028759
PRO2852	0.028682
C12orf45	-0.028641
BPY2	0.028632
AGO3	-0.028526
CAPN3	-0.028376
LHPP	-0.028323
ZNF213	-0.028281
CCL20	-0.028261
ARL17A	-0.027947
PTPRZ1	-0.027706
PLA2G2A	-0.027646
RFC4	-0.027635
ARMCX2	-0.027628
CIDEA	0.027578
ELP4	-0.027571
PPIL1	-0.027532
ATP12A	-0.027516
RHPN2	-0.027437
CYP4F8	0.027317
GSTM5	-0.027287
PRG2	0.027227
ZNF232	0.027194
PCP4L1	0.027194
CA2	-0.027050
TUBG1	-0.027047
SCD	0.027023
AGTR1	-0.027021
UPP1	-0.026919
STARD9	0.026841
PSPH	-0.026799
C19orf33	-0.026792
ELOVL3	0.026746
LOC100294362	-0.026727
ID1	-0.026687
MAL	-0.026633
CLDN8	-0.026524
DSG2	-0.026486
LRRN3	-0.026483
LYRM1	-0.026475
NDUFA4L2	-0.026462
RASA4	0.026462
STYXL1	-0.026449
EPSTI1	0.026411
XDH	-0.026264
CMPK2	0.026177
INTS3	-0.026176
HIST1H2AC	-0.026169
MLANA	-0.026149
TMCO6	-0.026138
HOXA5	-0.026115
CENPB	-0.026062
TSPAN33	0.026038
CD177	0.025988
MUC1	0.025984
GAFA1	0.025891
INSIG1	0.025885
ZNF593	-0.025848
CRISP3	-0.025829
C15orf40	-0.025808
FABP4	-0.025764
COL9A3	0.025745
ACAP3	-0.025738
ITGA2	-0.025683
TMEM56	0.025669
IL36G	-0.025631
RHCG	-0.025569
LOC286437	-0.025568
SFRP1	-0.025565
DZIP1L	0.025561
SLC52A1	-0.025499
LOC100130264	0.025464
HPGD	-0.025454
NLRP10	-0.025442
PCDHB14	-0.025404
NOP56	-0.025383
TMEM179B	-0.025333
CCDC80	0.025281
MTG1	-0.025133
DARS2	-0.025075
ZNF630	-0.025041
KLK6	-0.025012
MINPP1	-0.024952
ADAMTS2	0.024883
LINC01279	0.024882
IPO13	-0.024841
COQ5	-0.024819
PDGFRL	0.024819
REEP1	0.024803
COMMD8	-0.024787
HSPB6	-0.024752
FNDC1	0.024717
EPHX1	-0.024624
NPTX1	-0.024589
ADH1B	-0.024554
C14orf132	-0.024504
GZMA	0.024487
MAMDC2	0.024453
THAP1	-0.024402
GSTM3	-0.024363
FUT2	-0.024354
ENDOU	0.024333
WWOX	-0.024305
GK5	0.024300
IL2RG	-0.024263
FBLN7	-0.024248
SFRP2	0.024198
PRMT6	-0.024176
MSS51	0.024151
TRIM78P	0.024064
FLG-AS1	0.024061
AKR1B10	-0.024042
SLPI	-0.024018
FAM96B	-0.023983
HCG26	0.023959
UBL7	-0.023956
SUOX	0.023956
PAXIP1-AS1	0.023955
EPCAM	-0.023946
CNTNAP3	0.023931
TYR	-0.023911
FUNDC1	-0.023842
GBP4	0.023752
RUSC1-AS1	0.023679
ZNF597	-0.023676
FRZB	-0.023666
PHGDH	-0.023637
DCTPP1	-0.023566
ELF5	0.023487
MSH2	-0.023468
CCL17	-0.023437
INTS12	-0.023341
CHP2	-0.023316
NPAS2	0.023242
PAK1IP1	-0.023201
CXCL17	-0.023102
GCLM	0.023099
IFRD2	-0.023086
THUMPD2	0.023062
SMIM20	-0.023057
LOC729732	-0.023039
PARP14	0.023023
SULT2B1	-0.023021
ALOX15B	0.023002
SLC39A4	-0.022962
MOGAT1	0.022958
SOX6	-0.022947
LOC284242	0.022909
LOC100131564	-0.022898
FASN	0.022859
PLOD3	-0.022770
SEC14L4	0.022769
RAB38	-0.022756
LAGE3	-0.022755
EID3	0.022732
F3	-0.022729
FLG2	-0.022714
HIST1H3F	-0.022710
MET	-0.022618
LIPT1	-0.022596
STXBP1	-0.022582
KLHDC7B	0.022581
ELN	0.022546
CD83	0.022480
HSD3B1	0.022467
FAM26E	0.022461
VPS39	0.022449
CD274	0.022439
SCUBE2	-0.022359
HSPH1	-0.022339
ABHD17A	-0.022326
MRPS33	-0.022322
ITGB7	0.022288
ADIPOQ	-0.022253
RELN	-0.022218
TDP2	-0.022207
CYP39A1	-0.022194
APOL3	0.022191
CDK2AP2	-0.022186
ADORA2B	-0.022174
LOX	0.022136
TTC1	-0.022103
MYO5C	0.022098
DCD	-0.022084
BCL2A1	-0.022018
NEK2	0.021974
LRRC18	0.021916
IL36RN	-0.021890
POLE2	-0.021886
VKORC1	-0.021869
WFDC21P	-0.021860
SUCNR1	-0.021837
FAM127B	-0.021824
DYNLT3	-0.021816
MRPS9	-0.021805
VIMP	0.021798
THSD4	-0.021787
KLHL11	-0.021782
LOC100129112	-0.021781
KIT	-0.021779
GCH1	0.021766
COPS7A	-0.021748
TSPAN31	-0.021733
C8orf88	-0.021713
ADAM15	-0.021709
CCND1	-0.021702
IFI35	0.021695
LINC01003	0.021692
SH3BP4	-0.021679
PADI1	0.021579
OR2A4	-0.021540
F2RL1	-0.021535
RTN1	-0.021532
C9orf91	0.021524
SCFD2	-0.021440
PALD1	0.021426
RITA1	-0.021414
CCDC102B	0.021410
HOXB7	-0.021385
SSFA2	-0.021378
TLCD2	0.021377
MOCOS	0.021333
LRTM2	0.021324
ANXA3	-0.021315
SCARNA17	-0.021307
LOC101928837	0.021278
SLC12A2	-0.021271
SNX10	-0.021265
ZC3H6	0.021239
EGR2	0.021232
OPN3	-0.021217
TSPAN8	-0.021113
CDCP1	-0.021102
MT1H	-0.021079
NRM	-0.021077
CTAGE9	-0.021077
DSC2	-0.021074
GINS3	-0.021057
GBAP1	-0.020978
MT1X	-0.020943
AHSA1	-0.020928
ZYG11A	0.020915
GAPDHP62	-0.020893
COX16	-0.020860
TSNAX	-0.020806
LOC100131541	-0.020786
GABRP	-0.020786
FAM127A	-0.020783
RHOBTB3	-0.020777
NHEJ1	-0.020764
APELA	-0.020749
ZBTB25	-0.020736
FRAT2	0.020688
LOC284837	0.020670
PNP	-0.020655
INTU	-0.020641
ATP13A1	-0.020631
CEP55	-0.020612
HYOU1	-0.020610
PLD1	-0.020610
RPL22L1	-0.020606
FAM217B	0.020560
ZNF750	-0.020560
HSPBP1	-0.020544
CGRRF1	-0.020525
GTF2H2	-0.020493
SPRR2C	-0.020460
LINC00998	-0.020435
ADRB2	-0.020405
NPR3	-0.020363
LRRC15	0.020357
SMG1P5	-0.020330
MUCL1	-0.020307
CHAMP1	-0.020292
ZBTB21	-0.020289
PCOLCE2	-0.020260
TRIM39	0.020250
ALG8	-0.020237
ETHE1	-0.020200
LOC283788	-0.020189
LPAR3	-0.020167
ABCA12	-0.020156
FNBP1L	0.020155
KGFLP2	-0.020139
ROGDI	-0.020133
PLEK2	-0.020132
PAQR6	0.020032
MROH6	-0.020010
MTMR12	0.019991
RGP1	0.019979
SOAT1	0.019948
C18orf21	-0.019947
CIDEC	-0.019927
LOC100505851	0.019926
EIF2B3	-0.019925
IGLL3P	0.019924
POLR3F	0.019915
EIF4G3	-0.019883
PIP	-0.019883
STEAP4	-0.019876
MED9	0.019857
ENTPD3-AS1	-0.019851
TMEM54	-0.019834
EMB	-0.019833
MT2A	-0.019820
CDCA3	0.019813
PRB1	-0.019782
PECR	0.019767
ZNRF3	-0.019754
ITM2C	0.019723
KIF18A	-0.019721
AKR1C3	0.019712
BST2	-0.019711
TMPRSS11D	-0.019699
MACC1	-0.019682
HSD11B1	0.019677
USP45	-0.019665
DCUN1D2	0.019644
TMEM69	-0.019610
FBXO8	-0.019609
CUL1	0.019601
WDR45B	0.019589
CRIP2	-0.019577
NFIA-AS1	-0.019542
CTNNAL1	-0.019541
SRM	-0.019535
RASSF10	-0.019506
TRAPPC6B	0.019497
MPV17	-0.019489
CERS6	-0.019487
MRPL43	-0.019480
XYLT1	-0.019459
PSMB9	0.019454
PCSK9	0.019433
CCNB1IP1	-0.019429
C19orf70	-0.019427
TMEM68	-0.019392
MAOA	-0.019342
ZNF195	-0.019329
APOBEC3B	0.019310
SERPINB5	-0.019294
CLEC10A	0.019292
CHM	-0.019292
PCK2	0.019289
TIAF1	-0.019289
BEX2	0.019259
ST3GAL5	0.019239
EME2	-0.019231
SLC22A18	-0.019231
IER3	0.019222
SERPINB13	-0.019215
NXT1	-0.019213
ZNF418	0.019180
LOC101927587	0.019158
ALOX12P2	0.019153
PNPLA6	-0.019130
MAP2	-0.019116
MRPS16	-0.019086
GAL3ST4	-0.019083
LDHD	0.019067
ZNF107	-0.019051