!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	PLX4720
!smiles	CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
!pubchem_cid	24180719
!cell_type	HT29 3D culture cell - Day 1
!organism	human
!end_metadata
ALDH1A1	0.219931
TSPAN8	0.195626
ENO1	-0.160469
HMGCS2	0.116465
IER3	-0.115675
SLC2A1	-0.110847
ATP6V1B1	0.110706
AKR1C3	0.106707
HSPA8	-0.103652
HSPB1	0.102495
PMS2P4	0.102241
CRIP1	0.101731
TUBA1C	-0.097247
GCNT3	-0.095717
FTH1	0.092442
TRIM31	0.079889
PYGB	0.079599
FTH1P3	0.079080
EBNA1BP2	-0.078324
HSPH1	-0.075974
TUBA1A	-0.075162
TOMM40	-0.075143
KRT19	0.069803
COX5B	0.068156
DKC1	-0.067962
UCP2	0.067671
C20orf24	-0.065662
EIF4A1	-0.065220
RARRES1	0.063536
HIST1H4C	-0.063203
DNAJA1	-0.062906
ECH1	0.062739
LGALS4	0.062480
DCBLD2	-0.061266
PRDX1	-0.061147
SLIRP	-0.060950
GLTSCR2	0.060825
HSP90AB1	-0.060790
PSAP	0.060790
COX7C	0.059681
PSMB3	-0.058950
LDHA	-0.058616
NPC2	0.058526
PTPRF	0.057238
MYL6	0.056748
FASN	-0.056528
LCN2	0.056451
TM4SF1	-0.056115
FBP1	0.055528
ODC1	-0.055526
TMEM59	0.055181
COX6C	0.054952
TST	0.054602
S100A4	0.054520
UBE2M	-0.054271
SPINK1	0.053940
NME1	-0.053937
SLC7A5	-0.053650
RANBP1	-0.053534
CYB5B	0.052317
ANXA2P2	-0.051917
LOC729603	0.051708
DECR1	0.051263
PMM1	0.051076
TUBB4B	-0.050558
TXNIP	0.050541
GSTP1	0.050334
GPX4	0.050198
SMIM14	0.050179
NDRG1	0.050063
TACSTD2	0.050017
LYZ	0.049980
YBX3	-0.049921
HSP90AA1	-0.049730
GSPT1	-0.049567
UQCRBP1	0.049476
DCTPP1	-0.049449
TUBB	-0.048339
RAMP2-AS1	0.048120
AGO2	-0.047091
RPA3	0.046796
HADH	0.046636
MDH1	0.046446
IRAK1	-0.046426
VSIG2	0.046309
ZNF674	0.045942
NUDC	-0.045532
CCT2	-0.045521
SLC16A3	-0.045311
TUBA1B	-0.045295
RHOU	0.045234
H3F3A	0.045109
TUBA3FP	0.044630
TMSB10	-0.044605
EIF4A2	0.043522
EIF3B	-0.043287
PFN1	-0.043137
FBL	-0.042963
NUCB1	0.042850
CTSV	0.042763
BOP1	-0.042694
TNFRSF21	-0.042596
SNRPF	-0.041793
ATP5EP2	0.041579
PRR15L	0.041549
FAM115A	0.041265
COX6B1	0.041197
SNRPA1	-0.041189
CTSH	0.041106
PSMB6	-0.040815
LY6E	-0.040723
RPL30	0.040562
ALDH1A3	0.040343
PSMB2	-0.040209
POLR2F	-0.040135
RPL31	0.040014
TRNP1	-0.039957
HSPE1	-0.039809
KRT13	0.039733
HSPD1	-0.039714
SPINT2	0.039655
TMBIM4	0.039617
MYC	-0.039561
TXN	-0.039328
NDUFB5	0.039108
NDUFA1	0.038783
DDX21	-0.038442
UQCRQ	0.038416
ACTB	-0.038369
GARS	-0.038031
MAT2A	-0.037892
SLC44A4	0.037892
RPL27	-0.037528
FOXQ1	0.037394
LINC01420	0.037205
NDUFA4	0.037140
IMPA2	0.037016
AKR1C4	0.036749
MAN2B2	0.036650
LIME1	0.036619
ANXA10	-0.036480
B2M	0.036444
SNRPB	-0.036378
NCL	-0.036319
HNRNPAB	-0.036286
RAN	-0.036253
DAZAP2	0.035935
CYSTM1	0.035918
GTPBP4	-0.035914
PRDX5	0.035843
ATP5H	0.035738
NOP10	-0.035525
SPHK2	0.035153
RPL35	-0.035019
CD24	0.034869
TOMM7	0.034841
EIF5A	-0.034814
SCARB2	0.034766
KLK6	-0.034723
PPCS	0.034631
ATP5O	0.034544
SERPINB1	0.034505
MALL	-0.034484
CFD	0.034453
PTBP1	-0.034385
LDLR	-0.034375
RPS19	-0.034347
REXO2	-0.033938
PHLDA2	-0.033863
CDC37	-0.033806
STIP1	-0.033750
ZNF486	0.033670
S100A6	0.033578
HSP90B1	-0.033568
SRSF2	-0.033565
NDUFS8	0.033534
TOMM34	-0.033490
RPLP0	0.033393
PTDSS1	-0.033321
YWHAQ	-0.033072
TIMP1	-0.033007
RPL21	-0.032864
IL18	0.032598
COX6A1	0.032446
POMP	-0.032435
C1QBP	-0.032367
PKM	-0.032325
BRI3	0.032302
EIF4G2	-0.032254
POLE3	-0.032240
HSPA9	-0.032239
SRSF6	-0.032007
TESC	-0.031981
CALM3	0.031966
IMP4	-0.031897
RAB40B	0.031882
GABPB2	0.031861
TMEM54	0.031839
CALB2	-0.031781
SNRPG	-0.031740
RPS28	0.031716
ECHDC2	0.031711
KPNB1	-0.031660
FAU	-0.031571
ELF3	0.031531
JTB	-0.031516
COX5A	0.031397
STARD10	0.031259
CYBA	0.031239
DHX15	-0.031195
NDUFB10	0.031125
TNFRSF12A	-0.031043
COX7B	0.030862
POLR2H	-0.030668
PSMB7	-0.030608
EZR	-0.030518
MSLN	0.030453
CFL1	-0.030397
STRA13	-0.030360
CLIC3	0.030203
NDUFAF2	-0.030106
PPM1G	-0.030012
LDHB	-0.030005
CDK2AP1	-0.029999
RPL13A	0.029962
ASCL2	0.029793
PPP1R14B	-0.029741
CHCHD2	-0.029696
NDUFA3	0.029673
DERA	0.029540
MRPS6	-0.029521
FTL	-0.029466
NOP56	-0.029375
CSTB	0.029131
PUF60	-0.028994
XPNPEP3	0.028892
ZMPSTE24	-0.028887
PA2G4	-0.028776
BCAP31	-0.028727
DNAJB11	-0.028673
PAM	0.028472
PSMC2	-0.028466
PSMB1	-0.028419
MSRB2	0.028401
RPS6	0.028332
IDH1	0.028267
RN7SL1	0.028247
MGST3	0.028237
MRPS17	-0.028233
CETN2	0.028202
GNS	0.028179
EIF3I	-0.028157
MRGBP	-0.028043
GPX2	0.028002
CTXN1	-0.027975
NDUFB3	0.027896
LAMA5	0.027814
NSUN2	-0.027572
ATIC	-0.027483
RPL39	0.027433
LILRB3	0.027281
SERF2	0.027271
SERPINE2	-0.027270
MTAP	-0.027241
LXN	0.027153
GALM	0.027072
CSE1L	-0.027062
NAPRT	0.026955
LITAF	0.026953
ITPK1-AS1	0.026847
H2AFJ	0.026801
AKR7A2	0.026772
ATP5E	0.026769
TIMM10	-0.026712
FLJ43681	0.026686
EIF3F	0.026676
RPS7	-0.026667
GSTK1	0.026632
LYAR	-0.026436
CLDN2	-0.026104
ARPC3	0.026038
ITPR3	0.026015
TUBA4A	-0.025953
CAPN1	0.025932
NDUFA2	0.025893
HPGD	0.025809
ATRAID	0.025787
TGFBI	-0.025736
CENPB	-0.025684
CLDN3	0.025669
TPI1	-0.025653
CCT8	-0.025576
COX7A2	0.025540
PRELID1	-0.025519
CRABP2	0.025384
COPRS	-0.025357
RSL24D1	-0.025208
CIRH1A	-0.025172
SNTB1	0.025171
PTGR1	0.025098
CHP1	0.025067
BTG1	0.025023
RBM14	-0.024861
MRPL36	-0.024853
POM121C	-0.024835
ALDH9A1	0.024825
GTF3A	-0.024785
MANF	-0.024783
KIAA0101	0.024761
SRRT	-0.024748
NTSR1	-0.024732
SOD1	-0.024650
BRIX1	-0.024637
SCD	-0.024568
QARS	0.024565
RPF2	-0.024564
ARL6IP5	0.024560
NPM3	-0.024551
PSMC1	-0.024505
GNL2	-0.024334
CAMK2N1	0.024312
PLSCR3	-0.024305
ALDH3A1	0.024257
RPN1	-0.024243
ADRM1	-0.024172
GCHFR	0.024017
RARRES3	0.023970
ANP32B	-0.023949
HIBADH	0.023882
ORC6	0.023881
SLC52A2	-0.023718
BZW2	-0.023705
TMEM230	0.023522
RSL1D1	-0.023460
AHSA1	-0.023439
RABEPK	-0.023431
EIF1	-0.023349
NCOA4	0.023332
CMC2	-0.023294
BLOC1S1	0.023287
RHEB	-0.023217
FKBP4	-0.023198
HIATL2	0.023195
HOXB5	0.023183
PGM1	0.023162
SLC25A39	-0.023107
SRSF1	-0.023107
GRN	0.022993
CDKN2AIPNL	0.022957
RPS15	-0.022953
SLC25A6	0.022852
RPL13AP5	0.022812
LRP8	-0.022634
TOMM6	-0.022613
SDHD	0.022576
CKS2	-0.022546
F2R	-0.022535
COX4I1	0.022528
NDUFB11	0.022512
SET	-0.022463
GOT2	-0.022441
SLC7A1	-0.022398
NHP2	-0.022383
GLTP	0.022375
SIDT2	0.022371
IFNGR1	-0.022365
SOWAHC	-0.022272
SLC44A1	0.022261
ALPP	0.022170
FOXA1	0.022162
SQSTM1	0.022156
MAP4K2	0.022150
BMS1P5	0.022114
CXXC5	0.022098
MTHFD2	-0.022010
SQLE	-0.021951
APOD	0.021912
LMBRD1	0.021835
HIGD2A	0.021827
CAT	0.021822
SEPT9	-0.021689
ETS2	0.021686
PAFAH1B3	0.021598
PFDN5	0.021548
GMDS	0.021461
H3F3AP4	0.021406
DDX39A	-0.021406
FARSB	0.021347
WBP2	0.021254
AIMP2	-0.021242
CDH1	0.021239
LAMTOR2	0.021192
CYB5A	0.021178
INPP1	-0.021140
PROM1	0.021128
COMMD7	0.021067
IMPDH2	-0.021031
C1orf85	0.021031
ZNF430	0.021023
PSMB5	-0.020993
PLOD3	-0.020874
ADAP1	-0.020864
FKTN	0.020803
HEBP2	0.020755
MRPL17	-0.020737
TOMM5	-0.020707
AOC4P	0.020679
PSMD12	-0.020678
CDC20	-0.020672
RRP36	-0.020642
CCT7	-0.020638
MT1A	0.020601
MRPL14	-0.020599
GLA	-0.020594
PSMA5	-0.020579
NDUFS4	0.020579
COMMD3	0.020579
PTBP3	0.020540
JUND	0.020476
CLRN3	0.020474
RPS11	-0.020424
DBI	0.020415
TMEM179B	0.020390
KLHDC2	0.020379
ERH	-0.020299
DUSP19	0.020294
PET100	0.020273
LAPTM4B	-0.020241
ALDH7A1	0.020238
GSTO1	-0.020228
RRS1	-0.020196
YARS	-0.020188
CTPS1	-0.020174
MCM3	-0.020131
RPL6	-0.020113
SRP14	0.020037
RPP40	-0.020025
GATAD2A	-0.020020
RPL13AP20	-0.019994
STRAP	-0.019936
FAM213A	0.019868
PPA2	0.019833
TMEM14C	0.019827
ITGB5	-0.019820
CYP1A1	0.019785
MSN	-0.019726
ZNF549	0.019672
PAICS	-0.019646
ATP6AP1	0.019644
RPL29	-0.019619
BOLA2	-0.019546
DSCC1	-0.019541
HIST1H2BK	0.019512
ADSL	-0.019492
ZNF876P	0.019486
ZNF207	-0.019480
POLE4	-0.019413
COQ5	0.019374
SDF2L1	-0.019300
C11orf48	-0.019287
CCT3	-0.019287
ERGIC3	0.019239
ARPC5	0.019186
TMEM256	0.019186
ERRFI1	-0.019035
PSMD8	-0.019012
SLC35F2	-0.018987
EIF3K	0.018963
RPS27A	-0.018957
PRDX4	-0.018934
PSMC3	-0.018931
CST3	0.018916
KRT8	0.018864
NCLN	-0.018863
AXIN2	0.018828
FAM136A	-0.018822
PRRG2	0.018800
MYL12A	0.018781
ACSL5	0.018732
SHCBP1	0.018729
ATP6AP2	0.018692
ARHGDIB	0.018671
RRP7B	0.018670
DDX18	-0.018656
PRMT3	-0.018647
LOXL4	0.018581
C16orf58	0.018580
SLC1A5	-0.018566
LGALS1	0.018524
HNRNPD	-0.018513
UBB	-0.018490
RPS20	0.018478
GPX3	0.018465
TFRC	-0.018432
COX8A	0.018368
COBLL1	0.018351
YBX1	-0.018349
ABCC3	0.018314
COX7A2L	0.018301
COMMD6	0.018300