!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Cobalt dichloride hexahydrate
!smiles	O.O.O.O.O.O.[Cl-].[Cl-].[Co+2]
!pubchem_cid	24643
!cell_type	H4IIEC3 liver cell line - 29uM
!organism	rat
!end_metadata
HMOX1	0.168153
MAFF	0.087754
SLC2A1	0.086491
SLC7A11	0.082391
ERO1L	0.080108
CRYL1	0.079262
FABP1	-0.075410
BNIP3	0.075129
CCDC181	0.074455
EGLN3	0.073316
P4HA1	0.073116
NDRG2	0.069075
HAO1	-0.068626
PFKL	0.067476
PDK1	0.067436
MGARP	0.066892
APLN	0.066353
SMTNL2	0.065002
ANKRD37	0.064853
SLC40A1	0.064321
SLC48A1	0.063109
HMGCS2	-0.062552
DAPL1	-0.062086
DNAAF1	0.060808
TM4SF20	-0.058052
LOXL2	0.056999
RAB40B	0.055399
GYS1	0.054864
ABCA4	-0.054630
FBP1	-0.054376
KCNE4	0.053340
DDIT4	0.051072
PTGR1	0.050391
KDM3A	0.049965
SCTR	-0.049743
MTMR7	-0.049553
ADM	0.049346
TPI1	0.048888
LDHA	0.048786
RAPGEF4	-0.048765
HIGD1A	0.048687
PGM2	0.048597
GYS2	-0.047141
DHODH	0.046442
SPSB2	-0.046140
NAMPT	0.045679
EHF	-0.045063
JMJD6	0.044968
MANSC1	-0.044724
ALDOC	0.044674
SLC17A3	0.043518
SLC2A2	-0.043438
AKR1B10	0.043267
PPP1R3C	0.043238
GCLM	0.043012
PYGL	0.042978
FOXQ1	0.042956
ANGPTL4	-0.042547
LRP2	-0.041894
GSTA3	0.041791
AK4	0.040908
AMPD3	0.040790
ALDOA	0.040631
AOX1	0.040615
ME1	0.040597
NDRG1	0.040119
PIR	0.039329
BNIP3L	0.039144
GBE1	0.039033
GALE	0.038921
LPAR6	-0.038601
ITIH4	-0.038575
ABCC1	0.038293
MIF	0.038239
SLC30A1	0.038209
TXNRD1	0.037940
ANXA2	0.037874
WNT4	0.037861
SERPIND1	-0.037422
LGALS2	-0.036298
CLCF1	0.036266
NABP1	0.036097
ACOT2	-0.036039
SLC30A2	0.035981
CP	-0.035976
CRYAB	-0.035733
KYNU	-0.035609
STBD1	0.035529
ENO1	0.035434
SERPINE1	0.035410
SMPD3	-0.035396
CCNG1	-0.035348
FMO1	0.034996
TSKU	0.034954
ZNF143	-0.034935
MYZAP	-0.034905
CCDC58	0.034877
MYLK3	-0.034829
TBL2	0.034663
DNAJB9	0.034122
ZNF654	0.034058
SLC39A4	-0.033983
SLC35E1	0.033903
MBOAT1	-0.033790
CXCL10	-0.033681
DUSP12	0.033645
ABCB6	0.033598
ABCC4	0.033463
SLC17A1	0.033458
SLC27A2	-0.033267
ENO2	0.032675
PGK1	0.032316
SPP2	-0.032250
FGFBP3	0.032193
ATP7A	-0.032131
VNN1	-0.032107
SELENBP1	0.032082
VEGFA	0.032060
AZGP1	-0.031999
FBXO30	0.031808
SLC1A4	0.031690
FAM180A	0.031682
SLC7A7	-0.031377
TMEM37	-0.031176
GPR146	0.031096
NTN5	0.031038
IRAK2	-0.031000
CPED1	-0.030813
RTP4	-0.030716
PAQR8	-0.030610
KCTD15	0.030373
F10	-0.030307
C3	0.030200
TTR	-0.030138
SHPK	0.029579
AKR1D1	-0.029556
PLOD1	0.029518
FAM102B	-0.029374
OLFML3	-0.029364
CYP4B1	-0.029359
BAMBI	0.029291
DIXDC1	-0.029080
ADTRP	-0.028960
GLRX	-0.028915
P2RY12	-0.028867
GTSE1	-0.028778
MYOF	-0.028756
UGGT1	0.028755
ABCG2	-0.028732
GALK1	0.028651
CDH17	-0.028639
G6PC	-0.028639
SYTL3	-0.028552
TLR1	-0.028520
IRS1	-0.028437
PEX26	0.028294
GGCT	0.028217
NQO1	0.028160
ENTPD5	0.027878
AADAC	0.027871
RLF	0.027747
GSR	0.027724
PPAP2B	-0.027706
APBB1	-0.027686
C11orf82	-0.027595
MTHFD2L	0.027505
NR1H4	-0.027494
BHLHE40	0.027470
CITED1	0.027469
EXD2	-0.027358
HTRA1	-0.027290
ITIH3	-0.027271
NMRK1	-0.027248
ASL	-0.027237
ACOX3	-0.027217
NFE2	0.027187
H6PD	0.027155
PHF19	-0.027112
ACSS2	0.027091
KLF5	0.027088
PDGFRA	-0.027069
DUSP1	0.027038
RUFY3	-0.027037
FILIP1L	-0.026982
CPT1A	-0.026876
CLRN3	-0.026776
MIA	-0.026411
MRO	-0.026361
ERRFI1	0.026354
CASP3	-0.026227
THNSL1	0.026216
CYP1A1	0.026172
ABCC3	0.026159
GLS2	0.026096
AFG3L2	0.026062
CDHR5	-0.026038
ALDH1L1	0.026015
BIN2	-0.025972
CEBPB	0.025933
CCNG2	0.025923
WIF1	-0.025845
LMNB2	0.025837
ARHGEF26	-0.025836
ZMAT3	-0.025715
KDM4B	0.025673
EFHD1	-0.025646
ELL	0.025560
OSGIN1	0.025506
ARID3A	0.025502
CLDN2	-0.025491
GCLC	0.025478
BOK	-0.025478
HPS3	0.025464
ZFAND2A	0.025442
TFRC	0.025309
FOPNL	0.025291
GLOD5	-0.025256
MAP2K1	0.025226
IFI44L	-0.025192
NFIL3	0.025173
NFE2L2	-0.025034
TRPT1	0.024964
SNN	-0.024901
MACROD1	0.024900
ECI2	-0.024858
CCRL2	-0.024845
CMIP	0.024810
C11orf73	0.024653
TRIB3	0.024623
PRAF2	0.024601
PPP1R3B	0.024542
GAS2	-0.024536
NPTX1	-0.024507
LAMA3	-0.024461
NARF	0.024414
PHLDB2	-0.024377
P4HB	0.024288
BOC	-0.024271
CLCNKA	-0.024238
KXD1	0.024190
PIGR	-0.024188
ANKRD44	-0.024177
PLA2G15	-0.024065
CPT2	-0.024054
IL33	-0.023944
MYPN	-0.023941
VWA1	0.023922
TPMT	-0.023920
GRB14	-0.023906
CD36	-0.023903
SEMA3C	-0.023893
SLC38A4	-0.023884
TYMS	-0.023812
ISG20	-0.023810
TFCP2L1	-0.023711
SCD	0.023654
KANK4	-0.023651
MYOCD	0.023586
TRIP10	0.023585
RIPK4	-0.023525
MEX3B	0.023494
PHLDA3	-0.023477
OLAH	-0.023358
CASQ1	-0.023342
PRKAR1B	0.023238
CCRN4L	0.023225
IGF2BP3	-0.023214
KDM4C	0.023161
ARMC7	0.023161
PPP1R36	-0.023113
GPC4	0.023066
ZNF292	0.023039
UBE2O	0.023038
SAT1	-0.022976
ALDH3A1	0.022975
GAPDH	0.022964
SPIRE2	-0.022941
HDC	-0.022929
RNASE1	-0.022885
NEU2	-0.022871
CCDC34	-0.022856
MSH3	-0.022838
TRIM27	0.022797
NUCB2	0.022783
GLUL	-0.022762
ALDOB	-0.022722
UGP2	0.022694
COMT	0.022656
TMEM130	-0.022584
HSPB8	0.022485
PLAT	-0.022461
MTTP	-0.022435
IRF7	-0.022401
GNPDA1	-0.022392
COL8A1	-0.022366
ECH1	-0.022347
KCNK4	0.022345
UGDH	0.022340
CDKN3	-0.022332
RAB13	-0.022270
TSC22D3	-0.022248
BCMO1	-0.022236
SLCO1B3	-0.022203
LGALS1	-0.022138
SPIDR	-0.022097
PRKCE	0.022088
CEP70	-0.022065
PSPH	-0.022055
NEDD9	-0.022031
TGFA	0.021996
EPHX1	0.021977
ADAM10	-0.021970
TM4SF4	-0.021946
SH3BP5L	-0.021842
NME3	-0.021789
TRPV1	0.021728
TCP11L2	0.021644
PIK3C2G	-0.021578
CDKN1A	-0.021497
RAB32	-0.021469
GPATCH2L	-0.021456
GEM	-0.021430
C1QTNF3	-0.021428
FOXG1	-0.021411
F3	0.021389
PDZK1IP1	-0.021348
DDC	-0.021323
LNX2	0.021311
SLC22A5	-0.021258
VPS28	-0.021258
FUT1	-0.021210
POLA2	-0.021183
CIDEC	-0.021165
TNNC2	-0.021154
DOCK6	0.021138
RUFY1	-0.021130
LYST	0.021016
ZNF629	0.021010
SIGIRR	-0.020990
USP29	-0.020933
CREB3L3	-0.020886
POPDC2	-0.020884
POC1B	-0.020822
ZFP36L1	0.020794
CORO1A	0.020784
CYSLTR2	-0.020777
FKBP14	0.020748
CPA6	0.020715
RAD51C	-0.020715
PLA2R1	-0.020710
ANGPTL3	-0.020702
PDIA5	0.020692
CYP26A1	0.020687
ASF1A	0.020559
ZCCHC9	-0.020482
PLA2G16	-0.020460
RPP14	0.020456
ZFYVE1	0.020429
RAD51	-0.020428
CREG1	0.020404
MS4A7	-0.020395
LMO2	0.020375
ARL6IP5	0.020365
ARSK	-0.020337
DAPK1	0.020312
NPY2R	-0.020305
TMEM55A	0.020302
TNNI3K	0.020258
GUSB	-0.020253
CCDC141	-0.020225
SP110	-0.020223
ACAD11	-0.020214
TMEM106A	0.020183
GUCA1B	-0.020177
ABCA1	-0.020175
ST7L	0.020171
GPSM2	-0.020156
CATSPER2	0.020145
EMP1	0.020136
ANPEP	-0.020133
BCS1L	0.020127
IL1R2	-0.020116
GCKR	-0.020076
RAMP2	-0.020053
PLEK2	-0.019941
NAT8B	0.019939
FGFR3	0.019936
GADD45G	0.019857
FGF21	-0.019852
COA4	-0.019846
MED26	0.019757
FAM65B	-0.019753
CLDN6	0.019717
PLK2	-0.019715
ALKBH5	0.019708
TIGD3	-0.019693
OPN3	-0.019680
PSMB8	-0.019665
AATK	0.019658
SARAF	0.019636
NOTCH1	-0.019597
DPH3	-0.019597
KCNH8	0.019547
ACADVL	-0.019535
CD96	-0.019508
LPHN2	0.019498
DEDD2	0.019494
MMP11	0.019481
EIF4EBP1	0.019454
MGP	0.019431
UBE2L6	-0.019423
S100B	0.019369
IRF8	-0.019351
ANKRD1	-0.019345
CA6	0.019318
RHPN2	-0.019318
ZBTB7B	0.019266
ZNF182	-0.019237
FZD7	0.019229
PGAM1	0.019227
DAP	0.019215
IGFBPL1	-0.019192
TGM2	-0.019172
TNFAIP8	-0.019154
SLC22A4	0.019148
PLAC8	-0.019147
EPHA4	-0.019124
HDDC3	0.019102
AFP	-0.019090
CACNB3	0.019069
LRSAM1	0.019061
PIDD	-0.019060
TRIP13	-0.019058
ACACB	-0.019057
TMEM63A	-0.019041
CGRRF1	0.019041
TMEM205	0.019023
RNF38	0.019019
SERPINA6	-0.019019
MYOM2	-0.018986
STAB2	-0.018983
FOSL2	0.018962
RCBTB1	0.018933
NKG7	0.018927
CORO6	0.018921
NOSTRIN	-0.018911
EFHC1	-0.018896
CKM	-0.018830
FBN2	0.018795
IRF6	-0.018778
ART3	0.018775
DDX41	0.018752
CNST	-0.018733
CACNA1F	-0.018727
DEPDC7	-0.018722
ADRB3	-0.018712
INSIG2	0.018701
GSTA5	0.018691
ASNS	-0.018662
YPEL5	0.018662
STMN3	0.018657
FRMD6	-0.018606
ZNF519	0.018588
CHDH	-0.018564
RINT1	0.018559
TNXB	-0.018549
SIAH2	0.018530
CCNA2	-0.018527
RRAD	-0.018475
RHBDF1	0.018406
GDPD1	-0.018406
DNM1	0.018393
PDGFA	0.018378
TAF1B	0.018357
PTGES2	0.018348
TRIM54	0.018337
PSRC1	-0.018333
ACOT13	-0.018318
PTER	-0.018318
ASPA	-0.018311
CCNA1	0.018281
SLC43A2	-0.018275
ETFB	-0.018273
SOX18	-0.018267
CPPED1	-0.018253
RBBP8	-0.018227
SEMA6A	-0.018190
GCA	0.018136
NINJ1	0.018129
IFIT2	-0.018128
PARP14	-0.018127
ZNF777	0.018125
EDC3	0.018123
CENPN	-0.018120
RBM43	-0.018103
COLEC11	-0.018057
FRMD8	-0.018047
CLCNKB	-0.018044
ANKS4B	-0.018032
ACOT1	-0.018027