!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Tretinoin
!smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
!drugbank_id	DB00755
!pubchem_cid	444795
!cell_type	cranial neural crest - 24 Hours
!organism	mouse
!end_metadata
MDK	0.214930
HOXA5	0.203392
RBP1	0.173979
H19	0.171737
NREP	-0.134007
CTGF	-0.127686
CSN3	0.120804
ARG1	0.114838
FABP7	-0.108345
ANXA2	-0.100631
FAM107B	0.096958
TAGLN	-0.093811
ATF4	0.092258
TMOD3	-0.091013
TIMP3	-0.089655
DSTN	-0.087611
COL5A2	-0.086954
UQCRQ	0.084814
HOXA1	0.082757
IGF2BP1	-0.081819
GAS1	0.081818
PLAT	0.081231
RIN2	0.080004
SAT1	-0.078558
PRNP	-0.077911
CRABP2	0.076635
GSK3A	0.075105
TPT1	0.073608
RPS3	0.073511
PLK2	0.073350
TXNRD1	0.072367
CD63	-0.071180
RPL18	0.069006
SPSB1	0.067365
SLC38A4	0.067038
HDGF	0.066273
SOX2	-0.063544
RPL7	-0.062462
LAMP1	-0.062305
ATP1B3	-0.062215
TUBA1A	-0.061609
ARF1	0.060822
PLP2	-0.060004
NHP2	0.059486
BIN1	0.059283
CHD4	0.058961
SHROOM3	0.058749
TRIM28	0.057472
ENG	0.057109
F11R	0.056389
SMARCC1	-0.055817
GNAI3	-0.055704
CBFB	-0.055548
ACTB	-0.055518
WLS	-0.055321
ITM2A	-0.054879
FSCN1	0.054017
SLC3A2	0.053895
THBS1	-0.053886
RTN4	-0.053617
HOXB5	0.053597
COL7A1	0.053135
SKAP2	0.052753
PCBP2	0.052521
HSP90AB1	0.052008
PGRMC1	-0.051934
GSTO1	0.051719
SUMO3	0.051466
YBX1	-0.050127
ETV2	0.050073
MFGE8	0.049949
BRK1	0.049857
PMP22	0.049532
STMN4	0.049516
CACHD1	-0.049325
SSRP1	0.049040
DUSP6	0.049038
ACTA1	-0.048980
RPS15A	-0.048706
BASP1	-0.048278
ZIC1	-0.047842
RPS28	-0.047634
AHNAK	-0.047596
LIMS1	-0.047416
ABCF1	0.047183
SQSTM1	-0.046984
CST3	-0.046734
HMGN1	0.046690
PSMC6	-0.046329
EEF2	-0.046227
PRMT1	0.046172
ACAA2	-0.046162
BGN	-0.046143
NCL	0.046087
MAGED1	0.045844
KCTD10	-0.045572
MEST	-0.045226
ARL6IP1	-0.045211
ADH5	0.044847
FKBP4	0.044626
HSPA5	-0.044403
C15orf39	0.044095
RGS16	-0.043955
MGEA5	-0.043767
CDK4	0.043497
VCAN	-0.043445
LTA4H	0.043047
HSPA9	0.042642
ACTR3	-0.042540
SPATS2	0.042356
MYL7	0.042275
REV3L	0.041880
ITGB1	-0.041629
ACTG1	-0.041262
CDC20	0.041080
SKI	0.040986
NPM1	-0.040882
GLIPR2	-0.040817
ILK	0.040632
EXOSC7	0.040540
PARK7	0.040174
CSRP2	-0.040008
RPL19	-0.039811
MFSD1	-0.039667
RHOB	0.039583
NRAS	-0.039538
ACTC1	-0.039525
ERRFI1	0.039203
ENO3	0.039029
APEX1	0.038949
EEF1A1	-0.038837
CXCL12	0.038655
CCT7	0.038649
SNX6	-0.038550
U2AF2	0.038540
S100A6	-0.038304
ODC1	0.038120
PRDX6	0.037854
ANAPC5	-0.037648
SYPL1	-0.037491
JUND	0.037346
FZD2	0.037270
RPS5	-0.037267
LRPPRC	-0.037174
EI24	-0.037109
MAPK6	0.036963
DHRS3	0.036872
OTUD7B	0.036859
NDN	-0.036803
ARPC2	-0.036734
GLRX3	-0.036715
RPL21	-0.036446
GNL3	0.035999
COL1A2	-0.035842
PSMD7	-0.035770
HSPD1	0.035479
VAMP8	0.035313
MYH9	0.035274
VBP1	-0.035240
KCTD12	-0.035180
COL1A1	0.035068
APP	-0.034996
MAGED2	-0.034965
ANXA1	-0.034792
GNB2L1	0.034723
TSNAX	0.034625
MTCH2	0.034621
TSC22D1	0.034601
NDFIP1	-0.034524
MYADM	-0.034460
PPP1R14B	0.034348
NOP56	0.034100
TNPO2	0.034042
PDLIM1	0.033815
RPS27A	-0.033721
CTBP1	0.033647
PSMD4	-0.033521
WBP5	-0.033487
UBE2R2	-0.033285
ARHGDIA	0.033072
EIF3G	0.032986
PFDN2	0.032971
IGF2	0.032792
KDELR1	0.032716
HSPE1	0.032716
RDX	0.032491
DNAJC9	0.032461
CALU	-0.032337
NPC2	-0.032109
SLC39A7	0.031922
OSBPL5	-0.031894
PRDX1	-0.031808
TUBB3	-0.031749
PBX1	0.031728
HN1	-0.031690
RNF181	0.031595
G3BP1	0.031460
IMPDH2	0.031459
FOXC2	0.031398
NDUFS6	0.031394
ATP6V0C	0.031320
TSPAN9	0.031110
C20orf24	0.031048
TXNDC9	-0.031044
GAP43	-0.031017
AMOT	0.030899
TRIM27	0.030880
KLF6	-0.030860
CYFIP1	-0.030678
ID1	-0.030670
RNASEK	0.030611
SLC7A5	0.030540
DNAJA1	-0.030103
SRSF9	0.029895
H2AFX	0.029415
RPL3	-0.029398
RPS11	0.029370
GPX3	0.029255
LMNA	-0.029223
SLC2A1	0.029152
CSTB	-0.029123
PKM	0.028799
ARF4	0.028739
PRDX2	0.028716
PSMA2	-0.028539
DYNLL1	0.028508
TAGLN2	0.028399
CITED2	-0.028286
CLPTM1	0.028277
SNX4	-0.028158
PRKAR1A	-0.028132
RNF10	0.028052
SRSF2	0.028011
WARS	0.027995
CDCA7L	0.027949
TPBG	-0.027910
MTHFD2	0.027829
SAE1	-0.027755
PSMA3	-0.027727
CDKN2B	0.027645
RPL5	0.027640
CTPS1	0.027539
PLIN2	0.027517
MANF	0.027444
GART	0.027317
PTP4A1	0.027221
DDAH2	-0.027188
CDC6	-0.027171
PSMB3	0.027157
UBE2N	0.027137
BROX	-0.027079
DLK1	0.027025
PRPF19	0.026968
NDUFA9	-0.026963
RAB18	-0.026916
EXT1	-0.026858
SH3BGRL	-0.026735
IGF2R	0.026719
RSL24D1	0.026654
TSR1	0.026648
PDHA1	-0.026576
RHOC	0.026566
RBM3	-0.026541
MRPS18B	0.026476
FTH1	-0.026322
SNX3	0.026238
NDUFS2	0.026204
TUBB2A	-0.026196
FBL	0.026161
DNAJC10	-0.025728
MCAM	-0.025649
MORF4L2	0.025646
ITGAV	-0.025584
LARP1	0.025563
XPR1	-0.025508
LDLR	0.025501
UHRF1BP1	0.025492
EMP1	-0.025464
EGLN1	0.025383
NDUFB5	-0.025369
EIF3L	0.025250
EDN1	0.025175
PABPC1	0.025175
MARCKSL1	0.025151
IGF1R	-0.025107
CRIPT	-0.024980
HIGD2A	0.024918
NCKAP1	-0.024901
PSMC1	-0.024832
SGK1	-0.024810
CCNG2	-0.024700
FKBP1A	0.024611
BANF1	0.024499
RCN1	-0.024428
NAE1	-0.024416
DDX39B	0.024262
SFR1	-0.024225
KRT20	0.024218
RANBP1	0.024054
ITM2B	-0.024054
TMX1	-0.024008
COX7A2L	-0.023958
FAM120A	0.023915
CASK	0.023912
NR2F1	-0.023895
AIMP1	0.023885
KRT7	0.023702
RSU1	-0.023700
RPS10	0.023563
SENP3	0.023506
KDM3A	-0.023458
PPIC	-0.023365
MYL4	0.023296
TGIF2	0.023279
CLIC4	-0.023277
SARAF	-0.023258
FDPS	0.023177
PHF5A	0.023171
PGK1	-0.023169
RRS1	0.023161
KANSL2	0.023147
EIF4A2	0.023109
HOXB1	0.023061
SLC39A6	-0.023047
FST	-0.023038
PSPH	0.023021
LOC728392	-0.022973
TBC1D1	0.022928
PGAM1	0.022893
PHB2	0.022828
RSL1D1	0.022821
STRAP	0.022772
TKT	0.022746
FZD3	-0.022711
TCF12	-0.022675
ZNF207	-0.022659
CADM1	0.022583
RPL28	0.022556
HIF1A	-0.022544
H2AFV	-0.022537
FAM171A1	0.022459
GTF2I	0.022389
SF3B6	-0.022369
MTX2	0.022336
KLF7	-0.022305
MRFAP1	0.022287
ZWINT	-0.022285
PTTG1IP	-0.022285
B2M	-0.022262
ATP5A1	0.022248
TARS	0.022248
MYBPC3	0.022098
RDH11	-0.022074
LDHA	-0.022050
PPDPF	0.022012
MYL12A	0.021995
TMEM165	-0.021985
LAPTM4B	-0.021936
GPS1	-0.021908
YBX3	0.021870
S100A10	-0.021828
FAM60A	0.021808
LATS2	-0.021796
CARS	0.021754
SRM	0.021737
POLR2M	0.021637
ACTG2	-0.021607
STOML2	0.021585
RNF141	0.021566
PFN2	-0.021533
TNNC1	0.021479
DEGS1	-0.021384
HADHB	0.021375
SURF2	0.021372
ANAPC11	0.021354
CYP26A1	0.021314
TGFB1I1	0.021249
SYNPO	0.021213
MIDN	0.021146
ACTN1	0.021133
MATR3	-0.021047
IFRD1	0.021036
C12orf57	-0.021021
TIMM23	0.021013
PDCL3	0.020919
RPS12	-0.020813
SERINC3	-0.020804
MLLT3	-0.020778
RPS26	-0.020743
GDI2	-0.020720
TRAM1	-0.020637
STMN1	-0.020627
PEA15	-0.020614
BNIP3L	-0.020549
RASA3	-0.020505
DSP	0.020496
SGCE	-0.020471
WDR92	0.020463
CUL3	-0.020331
HNRNPK	-0.020289
TNC	-0.020279
HNRNPR	0.020239
PSMB7	0.020230
ATG12	-0.020221
LAMC2	-0.020214
CCT3	0.020187
RUVBL2	0.020169
FAM101B	-0.020136
RPL10A	-0.020116
SUGT1	-0.020095
DLX1	-0.020064
CCDC6	0.020042
UBE2V1	0.019995
TPI1	-0.019975
CLTC	-0.019955
AKAP12	0.019889
RBM17	0.019872
VPS4B	-0.019786
HSP90B1	-0.019777
CCT5	-0.019716
PPP2R1A	0.019702
GGA2	-0.019645
SERP1	-0.019640
PPID	0.019585
SOCS2	-0.019569
C11orf31	0.019564
NDUFA5	0.019563
UHRF1	-0.019552
POLDIP2	0.019530
CMTM7	0.019509
PJA1	-0.019398
TNFAIP8	0.019389
CAPZB	0.019382
GDI1	0.019380
BTF3	0.019370
CKB	-0.019284
CNN3	-0.019205
HSD17B4	-0.019197
EMG1	0.019186
CTSV	0.019054
RPL13A	0.018999
PPP3R1	0.018920
LARS	0.018907
NUDT4	0.018897
MAEA	0.018831
CNPY2	0.018828
MYEF2	0.018818
DHRS1	0.018811
PVRL2	0.018784
COPS6	-0.018708
CA2	0.018694
MDM2	0.018433
FAM103A1	-0.018433
UGDH	0.018389
ASAP1	0.018315
GABARAPL1	-0.018304
HSPB2	-0.018259
POLR2L	-0.018235
ATP6V0D1	-0.018200
NRIP1	-0.018164
NPEPPS	0.018087
PSMC3	-0.018076
VMP1	-0.018038
LPP	-0.018031
GLO1	0.017999
SERPINB6	-0.017991
PABPN1	0.017880
SEPT7	-0.017833
SPTLC1	-0.017814
PSMD6	0.017808
PSME4	-0.017744
ANAPC4	-0.017738
ETF1	0.017723
TIMM13	0.017698
PSMA5	0.017695
WDR77	0.017639
CKS1B	-0.017554
RBFOX2	-0.017504
FN1	-0.017491
MCL1	0.017462
SERPINE2	-0.017442
SURF4	0.017391
UBE2G1	-0.017390
WBP1L	-0.017364
CLPP	0.017341
MRPS14	0.017317
PSMA4	0.017289
FADS1	0.017276
RBBP4	-0.017270
DAP3	0.017239
PSMD5	-0.017224
TUBA1B	0.017169
SEC61G	-0.017137
RARS2	0.017130
ACO2	-0.017128
MAD2L1	-0.017127
COX17	0.017014
ZNF644	-0.017011
MFAP2	-0.016963
PPP2R4	0.016941