!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell_type	MCF7cells
!pert_name	estradiol
!pert_id	PubChemCID:5757
!organism	human
!pert_type	chemical
!end_metadata
IFI27	0.090112
SIGLEC6	-0.086732
VTN	0.072774
APOD	0.071852
SGCE	-0.068287
MUCL1	0.067004
BST2	0.066664
CDH10	-0.060770
NME4	-0.060305
GPNMB	0.057819
SHISA2	0.056786
ZNF175	-0.055168
H19	0.055150
ZNF22	-0.054667
PLEKHS1	-0.053696
S1PR3	0.052684
KRT81	0.052604
ACTG2	0.051828
VTCN1	-0.051369
CTGF	-0.051120
KIAA1324	0.050649
GDPD3	0.050462
ABCC2	0.050035
TEX19	0.049074
SLC2A3	-0.049030
HIST1H4H	0.048921
PRSS23	0.048784
ANXA1	0.048774
CYP26B1	0.048738
CLDN9	0.048597
HSPB8	0.048530
STC1	-0.047442
TFAP2A	-0.047219
BCL2	0.047184
BNIPL	0.046022
CTGF	-0.046012
GJA1	-0.045650
TIMP3	0.044990
HOPX	0.044947
NDRG1	-0.044681
C15orf48	0.043398
SLC2A10	0.043367
GGT6	0.043239
FLRT3	0.043185
ZNF22	-0.042583
MGLL	0.041741
AKR1C2	0.041620
ACHE	0.041589
CDKN2B	0.041433
TARP	0.041123
GFRA1	0.040448
DTWD1	-0.039789
AR	0.039711
TM4SF4	0.039233
SUSD2	0.039184
MT2A	-0.039179
C1orf106	0.039081
CDKN2B	0.038557
AKR1C3	0.038528
NRCAM	0.038109
GFRA1	0.037902
KITLG	0.037690
MT1A	-0.037597
BCL2	0.037515
TENM3	0.037068
ERP27	0.036963
TFAP2A	-0.036931
GHDC	0.036826
PMEL	0.036617
CLDN1	0.036584
UPK3B	0.036405
KCNK2	-0.036371
DNASE1L2	0.036224
ST8SIA4	0.036027
CAPN9	0.036020
ST8SIA4	0.035476
UPK3B	0.035354
HPN	0.034888
IFI6	0.034732
NFIA	0.034724
C9orf152	0.034446
GFRA1	0.034293
FAM13A	-0.034193
EDN1	-0.034087
SCARNA13	0.034046
RHOBTB3	0.033973
PMS2P4	0.033952
TSKU	0.033868
CEACAM5	0.033862
DNAJA4	0.033763
MT1X	-0.033715
UBE2L6	0.033676
NUPR1	0.033645
MMP10	-0.033487
NAV2	-0.033366
ACTA2	-0.033242
HPN	0.033179
EFHD1	-0.033178
UPK3A	0.033146
MUC1	0.033081
PXMP4	0.033016
MAPK4	0.032957
MDK	0.032612
UPK3B	0.032540
TFF3	-0.032537
CDC45	-0.032445
CYP4B1	0.032397
NPHP3	-0.032359
MUC1	0.032260
NRCAM	0.032234
MVP	0.032218
CYP4B1	0.032216
PCGF6	-0.032175
MOB3B	-0.032156
HEY1	-0.032136
FAM214A	-0.031813
MGLL	0.031768
ARPP19	-0.031670
RORC	0.031644
KITLG	0.031581
GPNMB	0.031391
RORC	0.031365
HCAR1	-0.031310
PAQR7	0.031225
UPK3B	0.031195
PALLD	0.031192
HIST1H2AC	0.031169
MYO16	0.031121
HIST1H2BD	0.030943
SLC2A10	0.030837
ANXA3	0.030811
TK1	-0.030808
AOX1	0.030730
FAM214A	-0.030704
CRABP1	0.030627
HIST1H2BD	0.030626
HBEGF	0.030612
KCNK2	-0.030481
ALCAM	-0.030355
GULP1	0.030338
PYGL	-0.030231
QPRT	0.030170
ATP1B1	-0.030044
ADIRF	0.030011
KRT24	-0.029772
LIMCH1	-0.029382
DUSP16	0.029302
FAM198B	0.029224
FAM65C	0.029146
EDARADD	-0.028731
SERPINE2	-0.028698
ISG15	0.028639
FXYD3	0.028606
FAM13A	-0.028593
PRR11	-0.028590
MESP1	0.028351
TCIRG1	0.028281
GBP2	0.028265
NBEA	-0.028245
LEO1	-0.028197
LEO1	-0.028189
ACACB	0.027988
PCGF6	-0.027915
NUPR1	0.027872
DSP	-0.027717
TYMSOS	-0.027610
CCDC83	0.027600
TYMS	-0.027584
KIAA0513	0.027579
LFNG	0.027527
OPTN	0.027525
STOM	0.027484
DOK7	0.027469
UGT1A6	0.027438
IFI6	0.027423
PCNA	-0.027411
IFT122	0.027298
SLC7A8	0.027234
LAMB1	-0.027228
IFT122	0.027203
NCAM2	0.027191
MAP2	0.027181
RPS6KA2	0.027145
PLOD2	-0.027053
BLACAT1	0.027016
LAMB1	-0.026993
CAPN9	0.026953
CLIC3	0.026946
CDCA7	-0.026906
RERGL	-0.026842
KLF6	0.026819
STOM	0.026780
MYEOV	0.026779
MAPK6	-0.026770
TMEM123	-0.026769
FAM46C	0.026699
PARVA	0.026322
TMEM79	0.026194
MCM3	-0.026152
PKMYT1	-0.026089
TGFB3	0.026084
UGT1A6	0.026003
FAM46B	0.025842
S100A14	0.025802
KANK1	0.025779
MGP	0.025745
TIMP2	0.025662
ARPP19	-0.025619
CLIP4	0.025418
GSN	0.025376
CELSR2	0.025348
FXYD3	0.025341
UBA5	-0.025334
WNT10B	-0.025321
MGP	0.025302
DEGS1	-0.025226
C1QTNF6	0.025188
BHLHE40	-0.025154
MIR503HG	0.025113
PLOD2	-0.025045
HIST1H2BG	0.025035
BCL11B	-0.025016
AFAP1L2	0.024983
IGFBP3	-0.024953
PFKFB3	-0.024886
E2F2	-0.024832
PDE5A	-0.024773
TMEM139	0.024771
HIST1H2BK	0.024690
MECOM	-0.024659
PXMP4	0.024644
PEG10	-0.024641
P4HA1	-0.024631
TSPAN1	0.024589
ATP6V0A4	0.024586
BCO1	0.024581
ZNF467	0.024560
LPIN1	0.024554
MAST4	0.024551
LURAP1L	0.024521
KYNU	0.024511
UGT1A6	0.024420
PRPS1	-0.024375
SLC25A30	0.024346
CKMT1A	0.024298
BCYRN1	-0.024279
PXMP4	0.024248
S100A9	-0.024230
UPK2	0.024188
KIAA0101	-0.024176
CMBL	0.024143
USP8	-0.024123
FAM198B	0.024122
KIFC1	-0.024058
ASPH	-0.024052
RMI2	-0.024048
VGLL1	-0.024022
CBX5	-0.023879
NUCB2	0.023821
ENTPD1	0.023807
LEMD1	0.023804
MCM3	-0.023771
JAK2	0.023757
GNB5	-0.023737
SPPL2A	-0.023713
SCARA3	0.023701
MAP2	0.023662
FAM3C	0.023637
ADAM19	0.023554
TLN2	0.023539
HSD17B1	0.023464
KIF5C	-0.023457
PLA2G4F	0.023432
NELL2	-0.023429
KIAA1324L	0.023402
TUBB3	0.023286
ABLIM1	0.023254
ZNF91	-0.023239
HMGB2	-0.023216
ERC2	-0.023134
CYSRT1	0.023120
RHOB	0.023105
DPY19L1	-0.023051
MCM2	-0.023036
PRKCA	-0.023006
TGFB2	-0.023002
ATP6V0A4	0.022894
MCM10	-0.022894
AURKB	-0.022860
ATAD2	-0.022827
RCAN1	0.022808
HIPK2	0.022794
LPAR5	0.022704
RASL11B	0.022704
MYO5C	-0.022700
UBA5	-0.022699
UBA5	-0.022681
UHRF1	-0.022647
PROM2	0.022642
F2RL1	-0.022629
ZDHHC7	0.022601
TFPI	-0.022594
ISG20	0.022537
CAPN5	0.022517
CDKN3	-0.022514
CKB	0.022510
MND1	-0.022476
CKMT1B	0.022446
DIO2	-0.022419
HIST1H2BK	0.022409
CDCA5	-0.022403
RAB32	0.022387
RCAN1	0.022373
NCAPD2	-0.022306
TRPM4	0.022266
LY6G6C	0.022253
RAB27B	0.022247
MIR21	-0.022226
CAV1	-0.022208
MELK	-0.022207
UBE2E2	0.022169
ST8SIA4	0.022087
CYB5R1	0.022071
SPC24	-0.022069
DUT	-0.022015
USP8	-0.022000
ASS1	0.021993
ZNF280D	-0.021986
MCM7	-0.021978
PGM1	-0.021971
IFIT1	0.021965
GPR115	0.021916
ANGPTL4	-0.021899
TFF1	-0.021884
GPR110	-0.021877
HMGB2	-0.021869
XG	0.021853
LMO4	-0.021827
GRAMD2	0.021823
BMPR1B	-0.021814
HSPE1	-0.021779
EFNB2	0.021761
NR2F2	-0.021751
CGA	0.021730
CENPM	-0.021729
RAD51AP1	-0.021723
CCNB2	-0.021692
AKR1C4	0.021688
PSCA	0.021680
COLEC10	0.021680
MYB	-0.021637
DDIAS	-0.021625
C1orf194	0.021618
TMEM97	-0.021611
KIAA0101	-0.021597
CMYA5	0.021595
LINC00294	-0.021567
CHEK1	-0.021553
LCP1	0.021522
CDT1	-0.021472
ASPH	-0.021469
OIP5	-0.021457
SSPO	0.021455
MNS1	-0.021366
PRIM1	-0.021313
ALDH4A1	0.021299
PRC1	-0.021296
FAM83A	0.021262
N4BP2L2	0.021257
APP	0.021252
MB21D2	0.021241
RFC4	-0.021157
DRAM1	-0.021132
CDSN	0.021098
KIF11	-0.021092
WFS1	0.021081
MAPK4	0.021046
UBE2C	-0.021036
TCHHL1	0.021032
EGFR	-0.021028
AFAP1L2	0.021028
AGR2	-0.021016
BRCA1	-0.021011
RHOD	0.020992
ASS1	0.020975
PIK3C2B	0.020925
IRX4	0.020915
KCNK13	0.020912
EXO1	-0.020863
CLDN23	0.020856
KRT16	0.020850
SLBP	-0.020837
HIST1H2BC	0.020834
HIST1H1C	0.020796
OXTR	0.020782
TMCO3	0.020760
TEAD2	0.020757
FANCD2	-0.020724
MELK	-0.020708
SCCPDH	0.020707
CYP1B1	-0.020687
CDCA3	-0.020666
RHOQ	0.020662
FAM3C	0.020659
ZNF597	-0.020649
SAP30	-0.020647
IGFL1	0.020641
SULT2B1	0.020641
IGFBP5	-0.020632
IRF9	0.020629
PHLDB2	0.020606
ASPM	-0.020600
MCM5	-0.020596
ACOT1	0.020568
ARL4A	0.020556
PROM1	-0.020556
CPE	0.020532
SYT7	0.020515
PRIM1	-0.020515
OAS2	0.020497
LYSMD2	-0.020488
TESC	0.020477
NTN4	-0.020456
HPS5	0.020435
DLGAP5	-0.020427
NUSAP1	-0.020410
KPNA7	0.020392
FFAR2	0.020357
DLGAP5	-0.020330
PFKP	-0.020326
SIGLEC6	-0.020297
ARHGEF37	0.020259
MYC	-0.020247
MYO5A	-0.020235
NME2	0.020135
MND1	-0.020086
NCAPG	-0.020062
FANCI	-0.020058
AMTN	0.020047
TPBG	-0.020024
CENPK	-0.020016
SLC9A1	0.020008
TPD52L1	0.020008
RFTN1	-0.019973
PLEKHA6	0.019968
TPD52L1	0.019966
CASQ2	0.019937
HMOX1	0.019862
KLF13	0.019845
MID1	-0.019841
BIRC5	-0.019833
BCAS4	0.019817
KRTCAP3	0.019811
ANXA2	0.019803
ALDH3B2	0.019795
HIST1H4E	0.019776
FBXO5	-0.019754
F2RL1	-0.019683
A4GALT	0.019658
CCNA2	-0.019649
OAT	0.019619
RFX7	-0.019614
MCM6	-0.019581
CLDND2	-0.019533
CRISPLD2	0.019518
RPRM	-0.019506
CLMN	-0.019506
ASF1B	-0.019495
DEGS1	-0.019488
LYPD3	0.019459
CROT	0.019431
C3orf52	0.019427
RRM2	-0.019421
SALL4	0.019414
PCGF5	-0.019410
IFITM1	0.019409
PKP2	-0.019395
CDCA4	-0.019368
NCOA7	0.019366
MTHFD1	-0.019331
TFPI	-0.019325
CENPW	-0.019305
UBE2E3	-0.019303
ATP6V0E2	0.019258
TP53INP1	0.019252
BCAS4	0.019252
KIF14	-0.019193
STARD13	0.019156
DUT	-0.019138
S100A8	0.019099
ST6GALNAC2	0.019081
WNT3A	0.019069
MATN3	0.019068
ANO6	0.019067
MMD	-0.019065
PLOD2	-0.019059
SLC18B1	-0.019030
TMOD3	-0.019028
KLF4	0.019026
TNFAIP8	-0.019010