!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	DAPT
!smiles	CC(C(=O)NC(C1=CC=CC=C1)C(=O)OC(C)(C)C)NC(=O)CC2=CC(=CC(=C2)F)F
!pubchem_cid	5311272
!cell_type	Aortic valve interstitial cells
!organism	rat
!end_metadata
COL2A1	-0.126358
MIA	-0.115923
COL9A3	-0.105521
CILP2	-0.096095
OLR1	-0.095027
KCNA4	0.093068
WFDC1	-0.089286
SPON1	0.087667
CMTM5	-0.087564
C1QTNF3	-0.085976
EFEMP1	0.084663
NOV	-0.084269
SCRG1	-0.082530
MATN3	-0.079688
MALL	-0.075296
CXCL12	0.073856
HAPLN1	-0.073814
CYTL1	-0.071489
LECT1	-0.071153
CSGALNACT1	-0.070302
RCAN2	0.069907
FNTB	-0.069043
MS4A7	-0.068923
RBP1	-0.067785
MGST1	0.065828
TGFBI	0.065582
NID2	-0.063516
GPR88	0.062394
CDH10	-0.062037
SERPING1	0.061598
CA9	-0.061498
CLMP	-0.060108
PLEKHB1	-0.059865
COL23A1	0.058960
RRAD	0.058864
RASD1	0.058748
ENPP3	0.058503
OSGIN2	-0.058445
AFAP1L2	-0.057673
PAPSS2	-0.057383
MRO	0.057237
MMP3	-0.055594
DCN	0.055455
ADAMTS15	0.054574
ALDH1A1	-0.054428
CADM4	-0.053746
TAGLN	-0.053528
RERG	0.052338
THSD7B	0.051898
MGARP	-0.051811
COL9A2	-0.051615
DDAH1	-0.051415
ERG	-0.051015
BMP2	0.050969
IL1RL1	-0.050420
PTN	0.050250
BMPER	-0.050192
MLANA	0.050058
TGFB3	-0.049829
ALDH3A1	0.049658
TCFL5	-0.049483
COL9A1	-0.048916
ADAMTSL2	-0.048147
VCAM1	0.047773
MYL9	-0.047537
KIRREL3	-0.047505
PLAGL1	-0.047453
ATP1B1	-0.047040
CLU	0.046668
KIAA1217	0.046441
EPS8L1	-0.046174
PLCE1	-0.045985
AOX1	0.045075
SERPINB2	0.044778
ACTA2	-0.044754
HS3ST1	0.044677
SLC16A7	0.043464
FAM89A	-0.043338
FGF18	-0.043338
TNFAIP6	-0.043223
TMEM30B	-0.043154
GNAI1	0.042947
ETV1	0.042816
MYH14	-0.042650
IGFBP4	0.042550
DNAJC12	0.042461
COL27A1	-0.042130
RRAGD	0.041993
UCHL1	-0.041512
COX6A2	0.041396
CYP1A1	0.041393
ZDHHC2	-0.041128
MME	-0.041111
WNT5A	0.041071
MPPED2	-0.041042
POSTN	-0.040966
GPNMB	0.040960
ARHGAP24	-0.040911
NTF3	0.040841
RGL1	0.040675
FAM101B	-0.039946
FGL2	0.039661
KCNS3	0.039552
CHN2	0.039387
GDF15	0.039242
SEMA3D	0.038811
S1PR3	-0.038600
PKP1	-0.038488
EVA1C	0.038447
CIDEA	0.038377
GRB14	-0.038190
LRRC48	-0.037838
LPL	0.037682
HSPA2	-0.037651
KCNMA1	-0.037390
RIN3	-0.037340
IL6	-0.037285
CRISPLD2	-0.036979
GNG3	-0.036882
TGFA	-0.036817
PCOLCE2	-0.036753
SLC7A3	-0.036744
MEOX2	0.036694
HAS2	-0.036610
LOXL3	-0.036509
MRAP	-0.036493
PDGFD	0.036344
DYNC1I1	-0.036229
PTGDS	-0.035980
CRLF1	-0.035822
FZD8	-0.035715
SMOC1	-0.035462
LTBP4	-0.035334
SMPDL3A	0.035249
HSD11B1	0.035249
FSTL3	-0.035236
GABRA2	0.035071
RASL11B	-0.034847
CXCL2	0.034829
FGFRL1	-0.034768
NDRG2	-0.034717
CA3	-0.034681
PMEPA1	-0.034676
ABCC9	0.034628
GPC3	0.034541
SERPINB7	0.034360
LAMA2	0.034332
PTPRE	0.034100
BMP4	-0.033992
TMEM173	0.033992
HPSE	0.033940
NPR3	-0.033771
CLEC11A	-0.033737
MAP3K8	0.033737
PRKAR2B	0.033634
ADH7	0.033601
PXDC1	-0.033539
CFTR	-0.033472
CCDC3	-0.033337
ADARB1	-0.033165
FAM211A	0.033162
PALMD	-0.033094
RASSF4	-0.033069
AVPR1A	0.033001
PRSS35	-0.032793
ALDH1A2	-0.032692
GADD45B	-0.032597
AARD	-0.032587
NPW	0.032376
EHD3	-0.032344
HFE2	0.032308
CYP26B1	-0.032300
GPSM2	-0.032234
SDC1	-0.032166
SLC28A2	0.032099
WWP2	-0.031973
PENK	0.031948
SOWAHC	0.031782
AMPD3	0.031757
C3	0.031739
SEMA6A	0.031688
ANKRD1	-0.031603
PLIN4	0.031499
KLHL40	-0.031356
NABP1	0.031308
CAPN6	-0.031276
PDE4B	-0.031275
ENPEP	0.031259
LCN2	0.031258
CASP3	0.031200
CTTNBP2	-0.031160
DUSP5	0.031077
NEU1	-0.030993
CREB3L2	-0.030923
GPR12	-0.030879
MEGF6	-0.030634
GPR146	0.030573
AREG	0.030525
ENPP1	-0.030470
PDLIM4	-0.030219
COX4I2	-0.030204
S100B	-0.030187
ARHGAP44	-0.030085
GPR126	-0.029954
SGCA	0.029905
TMEM45A	-0.029844
GPM6A	0.029602
DOK1	-0.029591
ADM	0.029441
COL15A1	0.029409
TMEM100	-0.029341
DAPK1	0.029307
LIMS2	-0.029264
CCL13	-0.029118
GJA4	-0.029074
SPTA1	-0.029031
CEMIP	-0.028964
FAM19A5	-0.028956
NUAK2	-0.028941
GADD45A	0.028838
NEDD9	-0.028809
PTGER3	0.028746
ACKR3	0.028537
SLCO3A1	0.028530
CMKLR1	-0.028454
PLA2R1	-0.028428
SVEP1	0.028201
TMEM106A	0.028182
PAK1	-0.028102
KIF26B	-0.028063
GFAP	-0.028045
PCSK1	0.028018
TSPAN18	-0.027877
SERTAD4	-0.027790
FAM64A	-0.027786
RGS17	-0.027763
PRR15	0.027428
CDCA3	-0.027425
THY1	-0.027401
ASPA	-0.027379
FOXA2	0.027366
TENM3	-0.027331
FBLIM1	-0.027282
MYCT1	-0.027221
TLR2	0.027168
LMCD1	-0.027113
RRM2	-0.026941
IL1R2	0.026919
CREB5	-0.026854
ME2	0.026714
BAIAP2	0.026691
GFPT2	-0.026635
FRRS1	0.026611
AGPAT5	-0.026582
MMP15	0.026444
PSD3	-0.026426
VNN1	0.026423
NOSTRIN	0.026329
RCSD1	-0.026325
CTF1	-0.026315
TM4SF4	0.026291
COL5A3	-0.026260
ACKR4	0.026221
IL17B	-0.026103
GLUD1	0.025962
NOX4	-0.025920
ST3GAL6	-0.025892
SH2D4A	-0.025877
ITGA3	0.025875
RBPJ	0.025844
NRXN1	0.025843
DUSP6	0.025789
TLE1	-0.025783
FAM117A	0.025724
SLC6A6	-0.025531
NPTX1	0.025439
EDN1	-0.025420
JAK2	0.025360
FAM198B	-0.025322
TNFSF13	0.025283
DMBT1	0.025227
ADAMTSL4	-0.025163
CKS2	-0.025114
AMDHD2	0.025076
PKDCC	-0.025057
PROSER2	-0.025018
AHCYL1	-0.025017
BTG2	0.024995
TBL1XR1	0.024990
OSR2	0.024980
ADRB3	-0.024963
PPARG	0.024954
CDH11	0.024905
LSP1	-0.024875
CCNA2	-0.024840
INSIG1	0.024811
PPP2R2B	0.024803
IGF2R	0.024799
ACER2	0.024711
CFH	0.024650
CDK1	-0.024643
MMP9	-0.024635
PTP4A3	-0.024608
ABCA1	0.024560
GALNT3	-0.024554
GPR64	-0.024547
ERRFI1	-0.024501
GDA	0.024457
EGLN3	-0.024442
KNSTRN	-0.024425
MTSS1L	-0.024421
HELT	0.024361
AMACR	-0.024255
TRPV4	-0.024244
KCNK6	-0.024223
PANX3	-0.024185
AMIGO3	-0.024156
FAM20C	0.024132
SAT2	0.024086
PLEKHG2	-0.024051
CSRP2	0.023978
ANGPTL4	0.023970
SCX	-0.023961
CAV1	-0.023959
PPP1R36	-0.023938
FKBP1B	-0.023891
DACT1	-0.023837
VWA1	-0.023791
TMEM158	0.023769
NAP1L5	-0.023744
RASSF3	-0.023737
UBE2C	-0.023644
ADAM15	0.023628
PHOSPHO1	0.023502
SGPP1	-0.023472
RAI14	-0.023454
ADD3	0.023337
LURAP1L	-0.023318
SIDT2	-0.023297
ADA	-0.023284
P4HA3	-0.023282
DPP7	0.023280
HR	-0.023277
BRINP2	-0.023251
FIGF	0.023134
PTGES	-0.023131
PKHD1L1	0.023123
PODNL1	-0.023096
ARMCX4	-0.023092
TCN2	0.023070
ATP6V0A1	0.023049
CMTM7	-0.023029
LINGO1	-0.023024
SYT8	-0.023018
PCDH18	0.023016
VAT1	0.022887
FYN	0.022886
HMMR	-0.022853
ALDH4A1	0.022803
NUF2	-0.022743
SLC45A1	-0.022534
DUSP14	-0.022523
PDZRN3	-0.022475
SIX4	-0.022467
FAM83D	-0.022339
CCNB2	-0.022329
GPR37	0.022312
SCN1A	-0.022283
FAP	-0.022263
ID4	0.022248
PLK4	-0.022242
RGCC	0.022221
ADAMTS5	0.022198
SH3GLB2	0.022198
OSBPL8	0.022185
MGST2	0.022043
CHST10	-0.022037
MAP2	-0.022008
PDGFRL	-0.022003
LOX	-0.021867
GMPPB	-0.021849
RNF144A	-0.021845
TIMP3	-0.021843
FAM107A	-0.021813
ITGB3	0.021781
GLT8D2	-0.021745
COX6B2	-0.021743
FGFR3	-0.021738
GOT1L1	-0.021607
RAP1GAP2	-0.021580
PHLDB2	-0.021504
CORO6	0.021502
LDLRAD4	-0.021499
BACE2	-0.021477
FLRT3	0.021331
UAP1L1	0.021316
TMEM176B	0.021257
COL6A3	0.021241
FHOD3	0.021235
MAFB	0.021222
TPST2	-0.021172
SEMA6D	0.021162
BAIAP2L1	-0.021146
MKI67	0.021118
MGMT	0.021101
CEBPB	0.021028
AP1S2	0.020986
EXT1	-0.020980
WIF1	-0.020963
BID	0.020952
ZNF395	0.020919
SOX4	0.020919
VEGFB	0.020863
ACVR2A	0.020836
PDGFA	-0.020812
COL18A1	-0.020759
TESC	0.020746
SLC29A1	-0.020743
OPLAH	0.020715
TNN	-0.020710
COL11A1	-0.020705
FAM111A	-0.020698
EXO1	-0.020642
ROPN1L	-0.020616
SEPP1	0.020609
ACTN1	-0.020594
SFRP2	0.020555
GBP2	0.020537
ABCC4	0.020508
DTX3L	0.020496
FAM171B	0.020482
CYP4B1	0.020476
OLFML2B	-0.020394
NECAB1	0.020377
FAM189A2	0.020344
PTGS1	0.020329
ASPN	-0.020306
PODXL2	0.020260
LAMA5	0.020246
CCDC37	-0.020237
PRC1	-0.020165
CEACAM1	0.020152
IL18R1	-0.020146
HMCN1	-0.020137
JADE3	-0.020075
CYBRD1	-0.020067
PELI2	0.019991
ACAD11	0.019983
DOCK11	0.019949
MAOA	0.019925
SESN2	0.019879
GUCY1B3	-0.019867
CPQ	0.019805
SREBF1	0.019799
KIF20B	-0.019778
PODN	0.019777
KIF23	-0.019770
FBLN2	-0.019755
SKA1	-0.019721
PTPRG	0.019706
PBK	-0.019702
ASF1B	-0.019675
LIMCH1	-0.019675
ITGA7	0.019648
LPAR1	-0.019647
CNP	-0.019647
ALDH2	0.019639
RPP25	0.019638
GLS2	-0.019634
CP	0.019579
ESPL1	-0.019566
TMEM62	0.019546
SLC2A13	-0.019531
LBP	0.019490
IRAK2	-0.019413
NDRG1	0.019404
CERCAM	-0.019395
TNFRSF25	0.019341
ADCY8	0.019313
CDKN1A	0.019308
IDH2	0.019298
CNKSR3	-0.019256
P2RY2	-0.019239
CPXM2	0.019228
FAM63B	0.019222
GREM1	-0.019219
GLS	-0.019216
PTPLA	-0.019210
CTSC	-0.019184
GHR	0.019165
RGS6	0.019159
MARCH3	-0.019140
LCAT	-0.019135
G0S2	0.019108
A2M	0.019090
PXDN	-0.019073
LRRC8B	0.019058
TRIB2	0.019010
PRR5	-0.018934
COL6A2	0.018934