!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Tretinoin
!smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
!drugbank_id	DB00755
!pubchem_cid	444795
!cell_type	cranial neural crest - 12 Hours
!organism	mouse
!end_metadata
MDK	0.265800
RBP1	0.156272
EEF1A1	-0.141600
SLC38A4	0.140419
CSN3	0.134621
ANXA2	-0.120502
FABP7	-0.111813
CRABP1	0.106939
CKB	-0.105932
H19	0.104707
SOD1	0.097161
SOX2	-0.096539
MRFAP1	-0.093403
RIN2	0.091399
ARG1	0.090577
HOXA1	0.090196
RPS5	0.088354
GNAI3	-0.087900
ETV2	0.084162
HOXA5	0.082723
MORF4L1	-0.082452
SRSF9	-0.078806
RPS26	0.076131
SPSB1	0.075940
C20orf24	0.075356
SSRP1	-0.071283
MYADM	-0.070840
MSN	-0.070034
MEST	-0.069843
CTPS1	-0.069670
NREP	-0.069076
YBX1	-0.068926
PLIN2	0.068771
ERRFI1	0.067929
TMOD3	-0.066942
HMGN1	-0.065436
BASP1	0.064845
HNRNPM	-0.062033
ASNS	-0.062006
GAS1	0.061073
ACTG1	-0.060279
CACHD1	-0.060213
THBS1	-0.060002
EEF2	-0.059331
PTP4A1	-0.059262
LAMP1	-0.058687
IGF2	0.058596
PRNP	-0.058304
RANBP1	-0.057859
SNRPB	0.057677
TOP1	-0.057656
PSAT1	-0.057445
NCKAP1	-0.055535
CORO1C	-0.055407
EIF2S3	-0.055184
CRABP2	0.054415
GPC3	-0.054390
ACTA2	-0.053429
PDHA1	-0.053414
VCAN	-0.053298
TUBA1C	-0.053094
CCNB1	-0.052842
TRAM1	-0.052815
PLAT	0.051694
DSTN	-0.051683
CSNK1G2	0.051412
TIPARP	0.051360
RPL6	-0.051107
RBM3	-0.050997
SAR1A	-0.050766
SOCS2	-0.050652
IARS	-0.049949
ARGLU1	-0.049451
VAMP8	0.049419
YWHAZ	-0.049220
RPS10	0.048824
FAM60A	-0.048596
PDCL3	0.048437
IER2	-0.048378
WDR1	-0.048093
TUBA1B	-0.048071
AHNAK	-0.047654
BCAT1	-0.047304
CSDE1	-0.047260
PSMA2	0.047040
GJA1	-0.047003
SMC4	-0.046961
SSBP2	-0.046159
ZNF207	-0.046072
TRA2B	-0.045988
RBBP4	-0.045869
TPBG	-0.045406
CDK2AP1	0.045357
DLK1	0.045146
CSNK1A1	-0.045109
RPL37A	-0.045051
RPS15A	-0.044798
RAN	-0.044671
RPLP0	-0.044495
TUBB3	-0.044465
ACTR3	-0.044252
RPL21	0.044057
HSP90AA1	-0.043127
TUBB	-0.043034
TSC22D1	0.042021
ATP5A1	-0.041929
RPS7	-0.041913
SLC3A2	-0.041643
CLIC4	-0.041573
CBFB	-0.041122
GSTP1	0.040968
PDLIM1	0.040955
FHL1	-0.040770
SOX11	-0.040717
KLF6	-0.040700
ELAVL1	-0.040414
RAC1	-0.040265
CDC20	-0.040016
CITED2	-0.039807
GNB2L1	-0.039754
S100A6	-0.039750
LARS	-0.039723
PSMB6	0.039343
LDHA	-0.039315
HNRNPH1	-0.039186
AHCYL1	-0.039073
EIF3C	-0.038841
SUMO3	-0.038753
SPATS2	-0.038662
THUMPD1	-0.038563
SLC12A2	-0.038537
HOXB1	0.038131
NHP2	0.037821
TCF12	-0.037738
TRIM28	-0.037326
SH3BGRL	-0.037297
PCNP	-0.036681
RPL8	-0.036424
RBMS1	0.036380
ZFP36L1	-0.036282
CLTC	-0.036106
FKBP1A	-0.036056
GAP43	-0.035984
PSMB5	0.035871
CAPZA1	-0.035867
ENG	0.035805
AKR1A1	0.035787
PPP1CB	-0.035715
PSMA4	0.035527
YWHAG	-0.035407
SNRPD2	0.035247
PSMB3	0.035113
PSMA5	0.034979
CTSV	0.034948
UHRF1	-0.034851
CTGF	-0.034786
FOS	-0.034747
PGK1	0.034684
HN1	-0.034674
TMED7	-0.034609
NR2F1	-0.034334
GLO1	-0.034242
PDIA4	-0.034161
PSMD7	0.034150
ANAPC5	-0.034052
APP	-0.033806
CADM1	-0.033564
TUBA1A	-0.033401
PPA1	0.033358
RBFOX2	0.033341
ANKRD1	-0.033197
COMMD3-BMI1	-0.033170
ARL6IP1	-0.033149
SRSF2	-0.032907
MAGED2	-0.032734
DNAJA1	0.032722
ZIC1	-0.032693
EZH2	-0.032647
ENO3	0.032577
FKBP8	0.032507
POLR2M	-0.032465
IDH2	-0.032234
TRIM37	-0.032233
TXN	0.032146
RHOB	0.032079
HIF1A	-0.031969
CETN3	-0.031871
TPT1	0.031846
MGEA5	-0.031786
RARS2	-0.031763
PHF5A	0.031761
GLIPR2	-0.031758
PPDPF	0.031716
RPA1	-0.031582
BIN1	0.031541
UBE2G1	-0.031394
SLC25A4	0.031355
CD81	-0.031354
COPS6	-0.031297
NRAS	-0.031114
CSRP2	-0.031027
MED22	0.030995
MARCKSL1	0.030952
CNN3	-0.030867
AIMP2	0.030839
MTHFD2	-0.030745
TMED2	-0.030731
BGN	-0.030663
RAD21	-0.030617
BZW2	0.030537
SMC2	-0.030374
PABPN1	-0.030325
ZFAND6	-0.030171
EGLN2	-0.030122
STRAP	-0.030110
TRADD	0.030051
CRIPT	-0.029762
STMN4	0.029757
PDHB	0.029650
DRG1	-0.029501
FZD2	0.029367
ARPC1B	0.029252
PCBP1	0.029248
PKP4	-0.029197
SHROOM3	0.029083
SET	-0.028997
ATP1B3	0.028953
GSTO1	0.028849
LMNA	-0.028700
ARF1	-0.028515
PBX1	0.028480
DHRS3	0.028326
ZNF644	-0.028323
PSMC6	-0.028270
CHEK1	-0.028262
HSPA8	-0.028108
SYPL1	-0.027941
HDAC2	-0.027939
SPATA13	-0.027930
EI24	0.027919
GADD45A	-0.027845
S100A10	-0.027807
COL5A2	-0.027804
SEC61A1	-0.027792
CUL1	-0.027773
SEPT7	-0.027768
MDH2	0.027737
ARF5	-0.027582
NUDT3	-0.027502
ACTN4	0.027435
TNPO2	-0.027391
SUCLG1	0.027381
SEPT2	-0.027338
CA2	0.027191
PTGES3	-0.027114
OTUD7B	0.027110
RPL18	0.027044
PRKAR1A	-0.026875
ITGB1	-0.026846
AKIRIN2	-0.026769
TTC3	-0.026435
SEC13	-0.026378
SLC2A1	-0.026354
NDUFS2	-0.026330
ERH	-0.026329
GNB2	-0.026179
LGALS1	-0.026164
GNG5	-0.026160
MAGED1	-0.026060
SPNS1	-0.026054
SKAP2	0.026028
CNOT1	-0.025895
PROM1	-0.025851
PSME4	-0.025809
ARF4	0.025790
ELOVL5	-0.025751
SFT2D1	0.025534
MTPN	-0.025528
HSPA5	0.025509
CAPNS1	0.025489
BSG	0.025473
TXNRD3	0.025400
H1F0	-0.025277
CSRP1	0.025275
MYCN	-0.025264
DDAH2	0.025215
NRP1	0.025008
ANXA1	-0.024995
SQLE	-0.024972
CHD1	-0.024841
SERP1	-0.024840
CTNNB1	-0.024789
CARS	-0.024714
ARMCX2	-0.024708
PSMB7	0.024698
ECT2	-0.024637
SMIM7	-0.024591
RHOC	0.024545
UBP1	-0.024477
IGF2BP2	-0.024390
WLS	-0.024261
GGA2	-0.024158
SLC1A4	-0.024150
LBR	-0.024143
TMEM123	-0.024100
TARS	-0.024086
RASSF1	0.024082
LSM14B	-0.024040
RPL13	-0.023984
STAM	-0.023978
GTF2A1	-0.023681
DYNLL1	0.023636
C19orf43	0.023606
TOMM70A	-0.023577
COPB2	-0.023566
HNRNPH3	-0.023551
PABPC1	-0.023431
RSL24D1	-0.023414
SLC39A7	-0.023398
SOX4	0.023397
FKBP5	-0.023298
FBL	-0.023219
F11R	0.023216
HNRNPA2B1	-0.023212
ITM2A	-0.023025
IGF2R	-0.023024
REV3L	0.022980
COL7A1	0.022975
CAPZA2	-0.022801
CDK8	-0.022768
PDCD4	-0.022737
PSMA7	0.022719
TNRC6A	0.022717
ACAA2	-0.022698
HAT1	-0.022635
HNRNPLL	-0.022621
KPNA3	-0.022611
GPI	0.022548
SLC7A3	-0.022534
NDUFA5	0.022513
MCM7	-0.022507
SAMM50	-0.022444
CNN2	0.022305
CCNA2	-0.022139
LSM14A	-0.022111
ATG12	-0.022111
IPO5	-0.022063
ACTR2	-0.022038
CHD4	-0.022030
RGS16	-0.022012
PCNA	-0.021958
GOLM1	-0.021949
ILK	0.021937
USP1	-0.021923
EFNB2	-0.021920
RPS12	0.021874
CBX3	-0.021871
KDM3B	-0.021861
RPS23	0.021828
EIF3J	-0.021798
CCT4	0.021774
SMAD1	-0.021755
FYTTD1	-0.021755
MCM3	-0.021721
SF3B3	-0.021698
VCL	-0.021679
CDKN2B	0.021678
SIN3A	-0.021674
RPL19	0.021664
EIF6	0.021655
HBG2	-0.021647
LIN7C	-0.021552
PFDN6	0.021487
ZMYM4	-0.021481
LPP	0.021476
NDN	-0.021475
ID3	0.021461
FAM192A	-0.021442
SEC11A	-0.021441
C11orf31	-0.021393
DNPEP	0.021352
TKT	-0.021111
STOML2	-0.021093
ARIH1	-0.021073
IPO11	-0.020918
HSP90B1	0.020868
HOXB5	0.020852
NDUFS6	0.020842
RRM2	-0.020817
TXNDC9	-0.020759
EIF4EBP1	-0.020734
NUDT4	0.020671
CSTF2	-0.020656
CYTH2	0.020630
CHCHD3	-0.020540
PRPF6	-0.020511
HMGCS1	-0.020501
RNPS1	-0.020468
IGF2BP1	0.020440
WDR92	0.020392
ISOC1	-0.020334
EIF1B	0.020317
RALB	-0.020297
AP3B1	-0.020281
PSMB2	-0.020281
HNRNPR	-0.020214
C15orf39	0.020182
BCKDHB	-0.020176
PPIA	0.020146
ROMO1	0.020073
TAGLN	-0.019988
LRRC59	-0.019966
CPNE3	-0.019942
CAMK2B	0.019903
MORF4L2	-0.019899
COL1A2	-0.019855
PSMD13	0.019854
PDRG1	0.019823
CFL1	0.019821
PMP22	0.019810
DNAJC10	-0.019806
HBS1L	-0.019803
SPPL3	-0.019779
CTCF	-0.019755
EIF3L	-0.019695
NDE1	-0.019693
RTN4	-0.019681
LIMS1	-0.019599
SELT	-0.019539
ZNF281	-0.019530
G3BP1	-0.019484
GNAI2	-0.019450
QKI	-0.019422
HSD17B4	-0.019413
IDI1	0.019406
THRAP3	-0.019379
ARL4C	0.019371
MANF	0.019371
RALBP1	-0.019365
RABAC1	-0.019283
SMC3	-0.019247
FOXC2	0.019219
UBAP2	-0.019215
PARK7	-0.019194
SLC39A6	-0.019188
MINPP1	-0.019179
VTA1	-0.019117
ACTA1	-0.018985
CUL3	-0.018938
ARL2BP	-0.018913
SERPINF1	0.018898
COPA	-0.018840
OSBPL5	-0.018807
CDC42SE2	-0.018793
KLHL9	-0.018731
RABGGTB	0.018724
MED27	0.018724
GNL3	0.018723
CYP26A1	0.018655
HNRNPL	-0.018655
ERO1L	-0.018654
CYFIP1	-0.018651
ATXN7L3B	-0.018634
GTF2B	0.018562
RPL13A	-0.018539
PRC1	-0.018507
LONP2	-0.018475
POLR2G	0.018388
HSD17B12	-0.018386
CDC7	-0.018318
INPP5A	0.018303
SLC35B1	-0.018276
VPS35	-0.018273
RPL7A	0.018240
MARCH6	-0.018211
KCTD12	-0.018210
AURKA	-0.018182
COPS8	0.018082
ADD1	-0.018045
NAV2	0.018031
MEOX1	0.017984
FUBP1	-0.017975
FUT8	-0.017944
EPRS	-0.017922
CPSF4	-0.017853
SURF4	0.017830
CTDSP2	-0.017830
ACTC1	-0.017825
HSPD1	-0.017810
EID1	-0.017805
SAT1	-0.017790
COX7A2L	0.017764
NPC2	-0.017722
CDKN1A	0.017605
TMEM55A	-0.017603
PHLDA3	0.017600
TXNRD1	0.017549
CHTF8	0.017533
EIF4G2	-0.017526
ITM2B	-0.017510