!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 6 Hour
!organism	rat
!end_metadata
GLUL	0.255386
MGP	0.243589
RHOB	0.203362
TSC22D1	0.194495
PDK4	0.193944
TRIM63	0.189362
NR4A1	0.178427
HSPB1	0.143718
KLF9	0.117127
MYL2	-0.115248
MYF6	0.103616
ERRFI1	0.102581
ACTG1	-0.100280
TUBA1A	-0.099901
LGALS1	-0.098308
EIF4EBP1	0.098154
MAPK14	0.097438
TRIM54	0.096009
RPL26	-0.090459
DNAJB5	0.089780
DYNLL1	-0.086660
XDH	0.086496
CRYAB	-0.084053
MYL12B	-0.083925
NDUFS7	0.083769
TUBA1B	-0.083606
ZFP36	0.079881
UBC	0.077673
MYH2	-0.075819
PCBP4	0.075633
CEBPB	0.075347
ND1	-0.073940
ATP5H	-0.073717
ACTB	-0.072544
RPS16	-0.072464
HSPB6	-0.070866
PPP2R5A	0.070461
ND2	-0.070426
RPL12	-0.070220
COX7B	-0.069705
SVIL	0.069611
CD63	-0.068940
COX4I1	-0.068872
AMPD1	-0.067635
RPS17	-0.067379
YWHAH	0.063715
GPX1	-0.062559
RPL37	-0.062189
RPL7A	-0.061720
PARK7	-0.061556
UQCRC2	-0.060936
ASB2	-0.060642
ENO3	-0.059809
ND4	-0.059527
TNNI1	-0.057985
RPS21	-0.057230
NEU2	-0.056556
FABP3	-0.055291
ACTN2	0.055107
RPL9	-0.054829
RPS27L	-0.054710
IDH2	-0.054323
VDAC1	-0.054289
RPSA	-0.054224
SCHIP1	0.054188
MYH1	-0.053708
ATP5G2	-0.052944
CHRNA1	-0.052795
RPS13	-0.052513
ACAA2	-0.052111
OAZ1	-0.051710
PFKM	-0.051440
RPS27A	-0.050947
AKR1A1	-0.050904
RPL8	-0.050780
RPS4Y1	-0.050351
NFKBIA	0.049821
SDC4	0.049642
MPC1	-0.049412
AK1	-0.049379
ND5	-0.049344
APOE	-0.048858
RPL10	-0.048663
TCAP	0.048427
ATP5O	-0.048353
SLC25A4	-0.048125
FTL	-0.048109
CYTB	0.047999
TECR	-0.047401
PIM3	0.046165
NDUFA4	-0.046080
CCNG1	0.046017
NDUFA3	-0.045906
FAU	-0.045646
PPIA	-0.045213
CASQ1	-0.045172
H19	-0.045152
PYGM	0.045130
ATP5G1	-0.045085
WIPF3	0.044902
PTP4A1	-0.044844
MYADM	-0.044028
RPL27	-0.043761
MGST3	-0.043594
RPS23	-0.043328
KLHDC3	0.042933
NDUFV2	0.042775
COX3	-0.042640
IFITM3	-0.042604
RPS26	-0.042541
RPS9	-0.042501
SGK1	0.041994
CITED2	-0.041872
DDX3X	0.041763
FXYD1	-0.041073
EEF1G	-0.040971
PSMB5	-0.040796
COX5A	0.040758
ARF1	-0.040163
DUSP1	0.039479
RPLP0	-0.039203
MGST2	0.039133
RPL3L	-0.038998
MDH1	-0.038916
RPL18A	-0.037814
LDHB	-0.037634
MMP14	-0.037345
RPS25	-0.037078
RPS10	-0.036684
MAP1LC3B	0.036680
PPARD	0.036627
RPL27A	-0.036436
SPRY1	0.036147
COL3A1	0.035926
KLHL41	-0.035910
SEPW1	-0.035820
SLC2A4	0.035561
ITM2B	-0.035479
LCN2	0.035332
MYOG	-0.035276
RPLP2	-0.035062
PTPN3	-0.034700
PFKFB4	0.034578
LYZ	0.034543
FLNC	0.034032
IGF2	0.033804
RPL22	-0.033773
PSME4	0.033743
RPL11	-0.033591
RPS7	-0.033570
PPP1CB	0.033396
RPL13A	-0.033219
CTSV	0.032866
ATP5A1	-0.032658
RPS11	-0.032602
PPP1CA	-0.032512
RHEB	0.032494
ATP2A1	0.032455
NDUFB8	-0.032364
LDHA	0.032315
H2AFZ	-0.031831
RPL19	-0.031606
VIM	-0.031420
DCN	-0.031267
RPL18	-0.031213
RPS8	-0.031203
PSMD2	-0.030635
CEBPD	0.030553
SMPX	-0.030378
NUDT4	-0.030360
RPL28	-0.030095
UQCR11	-0.030058
CTSS	0.029863
LDB3	0.029831
VEGFA	0.029554
MYL4	-0.029483
RPS15A	-0.029438
CACNG1	-0.029420
TIMM23	-0.029233
NDRG2	-0.029002
BTG2	0.028965
ATP5F1	-0.028942
ANXA2	-0.028888
NDUFA5	-0.028555
RPS3	-0.028230
CKM	0.028121
UCP2	0.028114
BSG	-0.028046
PKIA	-0.028044
SLC28A2	0.027817
ASPH	0.027702
PFN1	-0.027593
ALDH1A1	0.027578
YWHAG	-0.027568
NDUFB3	-0.027560
AMD1	0.027463
GPX4	-0.027436
PABPC4	-0.027313
TIMM17A	-0.026871
LAMC1	0.026674
CYB5R1	-0.026483
PAICS	0.026132
HRAS	0.026085
RPL4	-0.025958
COX6A2	-0.025924
NDUFC2	-0.025865
PGM2	-0.025739
MORF4L2	-0.025638
PTGIR	0.025532
UQCRFS1	-0.025441
SERPINH1	-0.025408
AQP1	0.025360
LYVE1	0.025245
ATP5C1	-0.025174
RPS5	-0.025073
EMP1	-0.024825
SERPINE1	0.024790
B2M	-0.024769
MLLT3	-0.024611
RPL35	-0.024474
LOXL1	-0.024349
GNB2L1	-0.024061
SPP1	0.024025
LUM	-0.023775
RAB10	0.023754
ARL4A	0.023619
APRT	-0.023591
PEBP1	-0.023572
TMEM59	-0.023481
SNRPB	-0.023464
ANXA5	-0.023347
RPL6	-0.023204
TNNI2	-0.023167
ACSL1	-0.023073
RPL39	-0.022905
PDK2	-0.022757
PGK1	-0.022715
PECAM1	0.022581
COX6A1	-0.022544
NOL3	-0.022293
CHURC1	-0.022237
FABP4	0.022116
CAPZA2	-0.022114
NDUFS8	-0.022065
UBE2G2	0.022038
ANKRD1	-0.022002
NDUFB2	0.021999
RPL23	-0.021926
NRP1	-0.021836
RPL5	-0.021725
CXXC5	-0.021456
S100A4	-0.021401
CTBP1	0.021285
BCL2L1	0.021280
PRKAR1A	-0.021057
CD81	-0.020944
PRDX1	-0.020929
LOX	0.020794
SIRT2	-0.020746
FLOT1	0.020739
CTSD	-0.020668
DYNLRB1	-0.020573
CAPNS1	-0.020500
CD36	0.020225
PTOV1	0.019992
ATP1B1	-0.019944
COL5A2	0.019890
PTP4A2	-0.019813
AP2M1	-0.019769
CPA1	-0.019724
CXCL14	-0.019716
CAV1	0.019706
RRAD	-0.019662
SDHAF2	-0.019640
DES	-0.019552
MYBPC1	0.019537
TNS1	0.019447
PDHB	-0.019346
FABP6	0.019342
EEF2K	0.019311
PLAU	0.019137
ATP1B3	-0.019084
NDUFB5	-0.019083
ECE1	0.019075
ATP5D	-0.018880
NDUFA9	0.018879
NDUFB9	0.018879
CDC37	-0.018805
SLC16A3	-0.018795
COX2	0.018785
POMP	-0.018770
DLAT	-0.018704
SERBP1	-0.018621
GAS6	0.018593
RPS15	-0.018580
GABARAPL2	-0.018474
ATP5J	-0.018465
TOMM20	-0.018455
GSTP1	-0.018417
NME2	-0.018407
EEF2	-0.018257
SLC25A3	-0.018140
RPL24	-0.018132
SUB1	-0.018081
CLCN1	-0.017960
CPT1B	-0.017882
CTSH	0.017881
CAP2	-0.017814
MYL1	-0.017802
TSPAN8	-0.017791
POSTN	-0.017787
NPHP1	-0.017745
ARNTL	0.017688
RGCC	0.017643
THBS4	-0.017541
EDF1	-0.017479
COX8A	-0.017463
PSMC2	-0.017325
PSMC5	-0.017299
STAT5B	-0.017292
CS	-0.017282
PSAP	-0.017198
DBP	-0.017145
TUBB	-0.017081
CPT2	-0.017070
FDFT1	-0.017066
HES1	0.017035
SMARCD2	0.016993
CSNK1D	0.016912
GNG5	-0.016909
RPS6	-0.016847
EIF5B	0.016828
HADHB	-0.016826
GAA	-0.016735
PDHA1	0.016704
GMPR	0.016667
MYL12A	-0.016633
SH2B3	0.016622
RBBP7	-0.016491
CLU	-0.016484
BIN1	-0.016450
MYBPH	0.016444
YBX3	0.016418
PGAM1	0.016409
GPX3	0.016365
GRINA	0.016334
NDUFS4	-0.016257
FSTL1	-0.016247
CSNK2B	0.016195
IRS1	-0.016193
MYOD1	-0.016153
ATP6V1F	-0.016144
MYBPC2	-0.016106
CDO1	0.016065
AKAP1	0.016048
EIF4E	0.015923
IQSEC1	0.015916
DECR1	-0.015832
ACADM	0.015798
TMEM255B	0.015781
CLTC	-0.015674
ALDOA	-0.015670
RPL17	0.015670
CREG1	0.015597
NDUFB10	0.015570
TJP1	-0.015546
PLA1A	0.015517
PRKCDBP	0.015490
LAMTOR1	-0.015418
CSRP2	0.015379
SDC2	-0.015192
HSP90AA1	0.015159
RPL15	-0.015157
CD74	-0.015135
F2R	-0.015129
NRARP	-0.015012
EGLN3	-0.015008
TST	0.014953
IFRD1	0.014897
RPL14	-0.014844
SLC16A1	-0.014797
TSPO	0.014732
GRN	-0.014731
DRD3	0.014708
CSRP1	-0.014634
ANAPC16	0.014611
PSMA5	-0.014550
COX7A2	-0.014545
KLF4	0.014515
CST3	0.014484
CA3	-0.014470
UCP3	0.014463
CD48	-0.014452
VAMP5	-0.014446
BECN1	-0.014431
CTSB	-0.014408
CPE	-0.014399
RHOJ	0.014375
P2RY2	-0.014329
NEK7	0.014307
TNFRSF1A	0.014280
EGR1	-0.014265
RHOA	-0.014259
RPL36AL	-0.014215
PSMC3	-0.014175
NEXN	-0.014116
PSMA2	-0.014099
MAPK6	-0.014022
CAPG	0.013971
IGFBP6	0.013959
MAFK	0.013923
TCEB1	-0.013913
SYNJ2	0.013899
HSPE1	-0.013877
NDUFB6	-0.013867
ATP1B2	0.013850
ARRDC1	0.013785
SDHA	-0.013758
ARHGAP10	0.013751
ACTA2	-0.013718
TFRC	-0.013685
LGALS3	0.013667
GRB10	0.013643
TMA7	-0.013642
CYC1	-0.013597
PKM	0.013505
SCARB1	-0.013465
TSPAN3	-0.013438
TPT1	0.013363
PTPN1	0.013324
DNM1	-0.013287
SERPINE2	-0.013248
SQSTM1	0.013198
FGFBP3	0.013190
NDUFV3	0.013148
PSMB3	-0.013144
ALPL	0.013132
KCNJ11	0.013031
PF4	-0.013030
MEOX2	-0.012972
PRDX6	0.012942
NR1D1	0.012938
CYP4B1	0.012938
H1F0	-0.012931
RPL21	-0.012896
PRDM2	0.012875
AK3	-0.012859
SLC25A5	0.012800
PRKCG	0.012799
ODC1	0.012763
PRDX2	-0.012753
ANGPT2	0.012729
ACADVL	-0.012713
MYL9	-0.012698
TLE1	-0.012647
RHOC	-0.012647
ACTC1	-0.012641
MSTN	0.012614
UQCC2	-0.012587
RPL3	-0.012579
STK10	0.012505
HSPA8	0.012433
SHFM1	-0.012412
TNRC6B	0.012325
TNNT3	0.012319
RPS14	-0.012249
AHNAK	0.012211
SEC62	-0.012206
CSDE1	-0.012186
DNAJA4	-0.012174
IGF2R	-0.012159
DNPEP	-0.012120
ARNT	0.012116
GPAM	-0.012115
KARS	-0.012071
PRNP	-0.012064
ERCC1	0.012014
CRISPLD2	0.012003
RUNX1	-0.011982
EIF3D	0.011928
PSMB2	-0.011889
DAD1	-0.011873
ITGB1	-0.011856
NCL	-0.011845
KCNJ12	0.011833
JPH2	0.011820
C1D	-0.011811
G0S2	-0.011792
DLK1	0.011762
CXCR1	0.011723
ANXA6	-0.011696
SLC25A11	-0.011669
VCP	-0.011659
PSME1	-0.011656
BHLHE40	-0.011646
CD151	-0.011626
ACAT1	-0.011613
CKMT2	-0.011581
PLEKHA1	0.011577
VAMP2	0.011539