!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Phenytoin
!smiles	C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3
!drugbank_id	DB00252
!pubchem_cid	1775
!cell_type	frontal cortex
!organism	rat
!end_metadata
PPIA	-0.243169
SERINC1	0.201468
COX1	-0.179650
ZWINT	-0.141098
CYTB	0.127228
RPS15A	0.124748
SPARCL1	-0.118792
GPM6A	0.116344
RPS21	0.111943
CCK	-0.107397
PLP1	0.105759
ACTB	-0.104189
PRNP	-0.101680
PTGDS	0.099687
FAM107A	-0.097607
ND3	0.093215
CST3	-0.090795
TUBA4A	-0.090207
UBC	0.089578
IDS	0.083363
BCAS1	0.079678
SLC4A10	0.076879
SLC12A5	-0.074765
MBP	0.074153
RPL17	0.072903
GSTA5	-0.072394
HPCA	-0.072248
ATP6V1E1	-0.071687
GAPDH	-0.070181
RPS17	0.070014
RPL26	0.067987
PSMC5	-0.067618
ALDOA	-0.065296
SPTAN1	-0.064180
NAP1L5	-0.062470
MRFAP1	0.062280
ATP1A2	-0.062029
RPL37	0.061428
RPS3	0.060725
TUBB2A	-0.060598
YWHAE	0.060511
GLRX3	0.060441
GPM6B	-0.060398
ACTG1	-0.058643
GDAP1	0.058467
QDPR	0.057739
ELMOD1	0.057196
RPL15	-0.057028
RPS14	0.056987
CRYM	-0.056797
FKBP3	0.056634
CHCHD2	-0.056616
ARHGAP32	-0.055119
SOD1	-0.054657
NEDD8	0.054102
TIMM8B	0.053510
SNCB	0.053247
SLC22A17	0.053004
RPL28	0.052365
PVALB	-0.052143
SLC25A4	-0.051863
RPL10	0.051764
ND2	0.051263
RAPGEF4	0.051101
LINGO1	0.050483
NRN1	0.050131
SLC24A2	-0.049700
LAPTM4A	-0.049537
BSN	-0.049518
MAT2B	0.049320
RPL4	0.049007
AKR1A1	-0.048611
OAZ1	-0.048587
ABI2	0.048494
RPS27A	0.048267
COPS6	-0.048111
RPL13A	0.047997
RBM3	0.047892
CLSTN1	-0.047654
DDX5	0.047443
NCKAP1	-0.046790
RPS26	0.046732
RAPGEF2	-0.046168
MLLT11	-0.045960
MAP1B	-0.045924
SDHB	-0.045871
NDUFA8	-0.045861
NEFL	0.045759
FTH1	-0.045704
PEBP1	-0.045448
ATP5A1	-0.045230
ATP5L	-0.044740
LDHA	-0.044598
CEND1	-0.044119
TTC3	-0.044046
RPL27	0.043615
ATP5B	-0.043407
GNAS	-0.043053
NDUFB5	0.042667
RPL5	0.042303
YWHAQ	0.042258
CHST1	0.042194
NDRG2	-0.042065
PTN	-0.041899
WDFY3	-0.041618
STMN1	-0.041307
RIT2	-0.041154
CX3CL1	0.041151
EID1	0.041019
ATP6V1D	0.040737
APOD	0.040696
TPI1	-0.040630
RAB3A	0.040611
SCG5	-0.040370
HSP90AA1	0.040285
ARF1	-0.040005
ITIH3	-0.039778
ATP5J	0.039678
MORF4L2	0.039593
STMN2	-0.039571
RPS2	-0.039441
ND1	-0.039116
THY1	-0.039114
JUND	0.039092
MOBP	0.039027
ITM2B	-0.039006
MAP1LC3A	-0.038957
TSPYL1	0.038853
VDAC2	-0.038407
STRN4	0.038071
RPS24	-0.037971
NDUFB4	-0.037941
ITPR1	-0.037933
MMD	-0.037783
CTNNB1	0.037769
RPS6	0.037692
ATP5G2	0.037634
CYC1	-0.037276
CPEB4	0.037008
SNX2	0.036618
SYNPR	0.036484
PPP1CB	0.035900
MSMO1	-0.035865
LMTK2	-0.035843
SEPP1	0.035764
RPL3	0.035687
RPL6	0.035672
EEF1A2	0.035666
ARL3	-0.035453
CMPK1	0.035434
ATP5D	-0.035427
CAMK2N1	-0.035139
FKBP1A	-0.035123
TMEM50A	0.034938
COX6A1	-0.034892
ATP6V0D1	-0.034801
OXR1	0.034728
PSAT1	-0.034714
RPS19	0.034575
HIVEP2	-0.034539
CISD1	-0.034208
TACC1	0.034055
HMGCS1	-0.034038
GOT1	-0.033847
SLC25A5	-0.033647
ATF4	-0.033640
RPL38	-0.033524
PLK2	0.033467
RPL8	-0.033389
SYP	0.033167
PGK1	0.032987
CCNG1	0.032931
VSNL1	-0.032785
GLUL	-0.032768
TPT1	-0.032716
YWHAZ	-0.032630
SAT1	0.032591
ARC	-0.032527
NDFIP2	0.032493
COX7B	-0.032228
CELF4	-0.032098
UCHL1	-0.032031
PRDX5	-0.031611
ATP6AP2	-0.031474
GABARAPL1	0.031450
APOE	-0.031442
ATP5H	-0.031265
PFKP	-0.031242
COMMD3	-0.031146
TCEAL1	0.031022
RTN3	0.031002
EIF5A	0.030960
PPP1CA	-0.030926
S1PR1	-0.030608
SNCA	0.030472
HNRNPK	0.030113
CPE	0.030106
EEF1G	-0.030093
NDUFB9	0.030070
PCP4	0.029948
TOMM20	-0.029766
RPS11	-0.029723
CNP	0.029687
SLC25A3	-0.029662
PSMB4	0.029617
RPS20	-0.029526
HMGN1	0.029143
PSMC3	-0.029064
RPL18	-0.029061
CDK17	-0.029041
NDUFB3	-0.029031
ATP5F1	-0.028982
NDUFB11	0.028917
S100B	-0.028906
UQCR10	-0.028812
MAL	0.028789
ATP5J2	0.028715
RPL27A	0.028639
PIN1	-0.028300
ATP1A1	-0.028158
HRAS	-0.028104
DLD	-0.028099
CTXN1	0.028036
SEP15	0.027906
RNF115	0.027892
RPS9	0.027866
DUSP3	0.027808
FADS1	-0.027771
ID2	0.027725
ITFG1	0.027716
MEA1	0.027705
LMBRD1	0.027565
YWHAG	0.027509
NPM1	0.027424
CTBP1	0.027311
PFDN5	0.027245
PLCB1	-0.027196
DNM1	-0.027112
ANO3	-0.027104
NECAP1	-0.026869
GRM3	-0.026806
BSG	-0.026770
SEC62	0.026552
ETFB	-0.026514
ITM2C	-0.026449
SATB1	0.026334
SUCLG1	-0.026283
PSMB2	-0.026126
PTP4A1	0.026092
EMC4	-0.026071
TMEM65	-0.025916
OLA1	0.025882
DYNC1H1	-0.025781
CHMP5	-0.025735
ABR	-0.025716
NDUFA1	-0.025713
CNOT7	0.025644
SYNJ1	-0.025519
PPP3R1	0.025509
MRPL17	0.025394
PSAP	-0.025279
HSPA8	-0.025249
USMG5	0.025184
SORBS2	-0.025111
ACTR2	0.025106
PDAP1	0.024996
RPS15	-0.024976
ATRNL1	-0.024914
ARF3	0.024812
BEND6	0.024761
RPS23	0.024701
GLUD1	-0.024675
ALCAM	0.024628
MEIS2	-0.024616
ATP1A3	-0.024438
BAI3	0.024397
PLEKHB1	0.024305
PAK1	-0.024264
PSMA7	-0.024258
CA2	0.024254
GNG10	0.024237
UBL3	0.024231
STX7	0.024103
YBX1	-0.024080
RHEB	-0.024057
SEC61G	0.024054
RPL23	-0.024031
VDAC1	-0.023996
CHCHD10	-0.023976
ATP6V0E2	0.023894
RPS25	0.023857
SCG2	0.023750
LY6H	-0.023740
SEPT7	0.023686
ATXN10	-0.023583
GABRG2	0.023547
CKB	-0.023543
SNAP25	-0.023538
SV2B	0.023496
MARCKSL1	0.023491
PLCXD3	0.023413
BRINP1	-0.023388
PCSK1N	-0.023375
HSPA4	-0.023295
NSMF	-0.023236
GHITM	-0.023226
SNRNP27	-0.023129
TMX2	-0.023128
DYNLL1	-0.023117
ATP6V1H	-0.023109
DTX3	0.023082
RPL9	0.023036
MMD2	-0.022941
NDUFB2	0.022902
MAP1A	-0.022780
ATP1B1	0.022776
RAB2A	-0.022740
ATP5G1	-0.022735
CNRIP1	-0.022650
RPL21	-0.022610
ATP6V1G2	-0.022584
ANAPC5	-0.022534
UBE2M	-0.022529
RAPGEF5	0.022439
MYH10	-0.022436
ENO2	0.022393
LRRC4C	0.022170
MYCBP2	-0.022165
KCNMB4	-0.022134
HSPD1	-0.022112
NPDC1	-0.022090
MMP17	-0.022049
ARPP19	-0.022015
SAR1B	0.021999
TSC22D1	-0.021973
MSANTD4	-0.021894
MRPS33	-0.021833
NSF	0.021809
FAM84A	-0.021784
PSMB7	-0.021709
PPP2R2B	0.021524
NGFRAP1	0.021518
NAPB	0.021494
UQCRC1	-0.021476
TNNC2	-0.021464
TSPAN7	-0.021460
SUMO2	-0.021404
RRAGA	-0.021353
CFL1	-0.021314
NTSR2	-0.021253
KLHL2	0.021240
VAMP2	0.021175
TUBB4B	-0.021096
COX14	-0.021052
SERPINE2	-0.021050
DDT	-0.020958
HTRA1	-0.020932
DNAJA2	-0.020925
DOCK4	-0.020917
NAP1L2	0.020864
ARL8B	-0.020791
GRINA	-0.020789
SUDS3	0.020769
DKK3	-0.020746
CLTC	-0.020732
RYR2	-0.020682
EPDR1	-0.020656
PFN1	-0.020545
RPL11	-0.020529
PRKAR1B	-0.020519
POMP	-0.020500
SV2A	0.020434
NDUFV1	-0.020384
KCNV1	-0.020286
MLC1	-0.020247
SLC25A46	0.020135
PI4KA	-0.020135
RPL18A	0.020133
MPC1	0.020132
MAP2K1	-0.020117
OLFM1	-0.020042
CAP2	-0.019993
RPS12	-0.019991
MRPS18A	-0.019919
GABRA1	0.019882
SUMO3	-0.019848
RPS16	-0.019834
PRPF8	-0.019786
LPHN1	-0.019779
TOMM6	-0.019720
RPL19	-0.019686
CPLX1	0.019588
EGR1	0.019552
PPP2CA	-0.019416
CIC	-0.019415
NME2	-0.019407
SWI5	-0.019405
GSTM3	-0.019354
DDN	-0.019284
YWHAB	0.019197
KLHL9	0.019116
AP2M1	0.019091
ZDHHC20	0.019089
AURKAIP1	-0.018994
ARAF	0.018956
KCNC1	0.018953
NEFH	-0.018920
PSMA1	0.018893
LY6E	0.018866
RPL35	-0.018842
UBLCP1	-0.018815
KIF5C	0.018743
ABHD17A	-0.018710
VIP	-0.018688
RPS29	0.018653
BIN1	0.018616
RPS8	-0.018564
SCAND1	-0.018562
SERBP1	0.018502
PRICKLE2	0.018478
HPCAL4	-0.018455
SCN3B	-0.018443
WBP5	-0.018430
PCYOX1	0.018401
STK32C	-0.018395
G3BP2	0.018309
NDUFC2	-0.018284
GAP43	-0.018283
CAMKK1	-0.018176
NDN	0.018116
QKI	0.018109
CNR1	-0.018094
TECR	-0.018086
GARS	-0.017997
CD200	0.017991
SNX3	-0.017983
BLOC1S2	0.017959
FAM134A	-0.017951
PSMD14	0.017940
DGKZ	-0.017920
CUTA	-0.017883
SUGT1	-0.017874
NR4A1	-0.017864
FKBP2	-0.017833
FDPS	-0.017820
MRPL54	-0.017784
LMO4	-0.017778
RPS5	-0.017718
PHYHIP	-0.017705
SRP14	-0.017571
ATP2B2	-0.017556
ACO2	-0.017553
ACSL6	-0.017531
FTL	-0.017507
STUB1	-0.017469
FBXO9	-0.017419
RPL31	-0.017405
NAPA	-0.017384
NAP1L1	0.017355
CTSB	-0.017350
LHX2	-0.017344
VPS41	-0.017341
HEXB	0.017313
CTSD	-0.017307
ATP5G3	0.017185
SEC61B	-0.017144
STX12	-0.017134
RPS10	0.017127
DNAJC6	0.017119
BCR	-0.017080
HSPA4L	-0.017056
COX7A2L	-0.016992
EIF4H	-0.016964
ATP6AP1	-0.016961
LZTS1	-0.016950
PNRC1	0.016894
DEK	0.016802
NOP10	0.016799
YIPF5	0.016744
RAB6B	-0.016717
LUC7L2	0.016655
AP2S1	-0.016609
TMEM55B	0.016609
RPLP0	0.016578
RELL2	-0.016554
SCN4B	-0.016542
HOPX	0.016495
ARAP2	-0.016462
PSMA4	-0.016455
MRPL27	-0.016440
FAM173A	-0.016404
EEF1E1	-0.016399
ZNF365	-0.016377
ENO1	-0.016358
RBM39	0.016303
SYT4	-0.016299
RIOK3	0.016282
SEPT4	0.016280
NDFIP1	0.016196
TBPL1	0.016143