!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!cell	BR161
!perturbation	Afatinib 
!Time	48hrs
!Concentration	1000nM
!Relevant information	Resistant cell line 
!end_metadata
RPS2	0.184961
PHGDH	0.184181
RPL13AP20	-0.183511
TM4SF1	-0.161702
CAV1	-0.151580
ATP5B	0.146811
TACSTD2	-0.120990
GNS	-0.115914
RPL18	-0.111569
RPSA	-0.108694
RPS14	-0.100524
UBB	0.097544
FASN	-0.095140
GNB2L1	-0.093925
TNFRSF21	-0.088580
RPL24	-0.088215
FTL	0.087587
PSAP	0.084186
RPL23	0.083103
SEC61G	-0.082309
GAPDH	-0.080171
TPI1	-0.079495
MIF	-0.079122
RPS27A	-0.078769
GSTP1	0.077878
SCD	-0.077647
EEF2	-0.076684
ACTB	-0.075729
NME1-NME2	-0.073143
LGALS1	-0.073081
PFN1	0.071787
EZR	-0.071647
CST6	-0.071105
RPS19	0.070110
RPL35A	-0.069756
RPS28	0.069105
RPS25	0.068370
CDC20	0.066309
UBC	0.065571
KPNB1	0.064693
NDUFA1	-0.062976
COX4I1	-0.062743
LDHA	-0.062460
RPS12	-0.061696
COX7C	-0.061656
C20orf24	0.061627
EFEMP1	-0.061356
OAZ1	0.060936
RPS13	-0.060631
NARS	0.059359
PSMB3	0.058924
YWHAQ	0.058585
MRPL33	-0.058070
RPS6	0.057701
UCA1	-0.057400
BTF3	-0.056761
COX6C	-0.056371
LAIR1	-0.056259
RPL13A	-0.056210
HSPA8	0.055420
CYR61	-0.054573
LDLR	-0.054504
PRNP	0.054183
HSPB1	-0.054029
PRDX1	-0.053763
ALDH9A1	0.053404
RPL13AP5	0.053373
EEF1A2	-0.053000
EIF1	0.052346
SLC7A5	0.051648
YWHAH	0.050653
UPP1	0.049834
RPL6	0.049666
TRA2B	0.049298
ASNS	0.048904
MRPS6	-0.048658
VDAC1	-0.048324
MTHFD2	0.048021
DPYSL2	-0.047360
CD24	-0.047107
FARSB	0.046650
RPL8	-0.046583
BNIP3	0.046582
RPL39	0.046325
RPL35	-0.046253
RPL31	-0.046226
SHMT2	0.046011
NETO2	0.045279
OST4	-0.044757
C19orf33	-0.044554
PRDX4	0.044487
GARS	0.044168
RPL30	-0.044151
LINC01420	-0.043942
TUBA1B	0.043853
RPLP2	-0.043566
ANXA2P2	-0.043281
RRP7B	0.043150
ZMPSTE24	0.042931
HNRNPA1P33	-0.042809
RPL26	-0.042682
RPL36AL	-0.042473
ACTG1	-0.042349
JTB	0.042326
CAV2	-0.042209
RPL27	0.042201
TGFBI	-0.042122
PSAT1	0.042020
UQCRH	0.041644
RPS5	0.041572
EPRS	0.040787
RPS11	-0.040715
FAM84B	0.040563
TXNDC17	0.040522
RPS29	0.040471
DDIT4	-0.040470
RPL10A	-0.040242
TUBA1C	0.040241
RPL11	-0.039938
MYL12B	-0.039912
MFSD10	-0.039621
NQO1	0.039442
MDH2	0.039423
KRT7	-0.039355
CALM3	-0.039014
HSP90AA1	0.038955
SEPT9	-0.038462
NDUFS5	-0.038170
RNASET2	-0.038057
LAMA5	-0.037745
MT1A	-0.037537
FDFT1	-0.037464
RPS20	-0.037444
KRT16P2	0.037179
ORC6	0.037116
F2R	-0.037000
EMP1	-0.036905
WDR54	-0.036886
SPINT2	-0.036634
H2AFJ	-0.036588
MYL6	-0.036374
VDAC3	-0.036267
DERA	-0.035723
PLSCR3	-0.035576
PGM1	-0.035391
CEBPB	0.035205
RPL41	0.035043
PSMD2	-0.035001
TMBIM6	-0.034833
NIP7	0.034797
B2M	0.034769
POLE3	0.034646
EPCAM	0.034549
CAPZA2	-0.034534
RPL7A	-0.034269
CDH3	-0.034121
DAZAP2	-0.034053
PPA1	0.033913
RNF181	-0.033700
TRIB3	0.033649
GHITM	0.033560
CDH1	-0.033556
HSPD1	0.033342
SLC7A5P2	0.033326
TMSB4X	0.033199
IFITM2	-0.033150
YBX1	-0.033118
DDX39A	0.032970
OSBP	-0.032933
ERRFI1	-0.032909
DDX21	0.032830
CTNNA1	-0.032754
HMGN1	0.032648
PTTG1IP	-0.032485
NEDD8	-0.032445
MRPL37	-0.032301
SLC25A5	0.032277
SLC25A39	-0.032217
TSPO	-0.032162
S100A6	-0.032090
DDT	-0.031819
DNAJB11	0.031569
DRAP1	-0.031551
FAM98A	0.031189
CIB1	-0.031148
EPN1	-0.031144
LASP1	0.031075
PCBP1	0.031026
COX8A	-0.030891
DDX5	0.030716
AIMP2	0.030598
UBE2C	0.030515
GLRX5	0.030477
ENO1	0.030463
VIM	0.030253
SCNN1A	-0.030220
IMP4	0.029718
EFHD2	-0.029667
RPL19	-0.029479
SCARNA13	0.029476
TOMM40	0.029346
CENPB	-0.029333
HIST1H4C	-0.029288
DDOST	-0.029210
TRIP6	-0.029126
PPT1	0.029126
ALDOA	-0.029039
POTEF	-0.028992
G0S2	0.028965
SFTA2	-0.028895
TMEM14B	0.028868
RNA18S5	-0.028684
PCCB	-0.028673
VPS35	0.028642
RPL13AP3	0.028633
PLAU	0.028626
HSP90B1	0.028555
RN7SL1	0.028521
C1QBP	0.028513
YARS	0.028474
DEK	0.028443
PAPOLA	0.028407
PRSS8	-0.028390
CSE1L	0.028356
TRMT112	0.028315
CDK2AP1	0.028291
ACLY	-0.028276
XRCC6	-0.028166
NDUFB7	-0.028133
NOP58	0.028072
JUND	-0.027998
NDUFB8	-0.027977
EIF4A1	0.027958
GNB1	-0.027785
AARS	0.027704
FAM136A	0.027683
H3F3AP4	-0.027586
SLC2A1	-0.027500
RPL21	-0.027463
MRPL16	0.027353
PPIAL4B	0.027307
SLC3A2	0.027137
EIF3G	0.026980
ALDH1A3	0.026939
STRAP	0.026914
HNRNPAB	0.026871
MAPKAPK3	0.026829
RPL9	0.026795
BCAP31	-0.026739
GUK1	-0.026668
TCEAL3	-0.026632
PTGES3	0.026534
ATP5EP2	0.026418
PSME2	0.026408
SMS	-0.026266
SGSM2	-0.026128
AP2S1	-0.026055
PGK1	0.026031
ACTN1	-0.025898
PSMB7	0.025804
LAMC1	-0.025752
PROM2	-0.025558
TMA7	0.025417
GTF2A2	0.025302
GPI	-0.025258
F3	-0.025202
TPT1	-0.025023
MSN	-0.025014
GPT2	0.024972
ILF2	0.024965
SQSTM1	0.024915
TMED5	0.024897
PIK3R2	-0.024816
NCOA4	0.024745
H3F3A	-0.024744
INTS1	-0.024702
LAPTM4B	-0.024668
DCBLD2	0.024662
LSM1	0.024659
MAT2A	0.024631
CDC37	0.024628
PON2	0.024582
TNS3	-0.024504
VPS51	-0.024226
NME1	0.024195
TOMM70A	0.024178
CTSL	0.024084
PSMA3	0.023991
COX7B	0.023960
PDXK	-0.023886
RHOC	-0.023803
HMGCS1	-0.023707
AMY1C	0.023551
KRT19	0.023438
IL18	-0.023424
PSMD7	-0.023359
PFDN5	-0.023330
BMI1	0.023329
CALM2	-0.023271
TNFRSF6B	-0.023233
SLC20A1	0.023156
NXT1	0.023062
MARS	0.023023
SEC11C	0.022953
BUD31	0.022935
PCED1B	-0.022909
ROCK2	-0.022819
ARPC3	-0.022750
UQCRBP1	-0.022697
PRR13	-0.022660
ABHD17C	0.022618
CAMK2N1	0.022593
CLIC1	-0.022576
CKS1B	-0.022565
BASP1	-0.022476
DHCR24	-0.022288
MORF4L2	0.022270
COPS5	0.022052
KHDRBS1	-0.021944
NOL11	0.021863
MRPL3	0.021847
GNAS	-0.021829
SUMF2	-0.021781
SRP9	0.021773
RPS16	-0.021769
PSMC5	0.021745
S100A11	-0.021734
ALDOC	-0.021514
DENR	0.021434
TRNP1	0.021430
CCT6A	0.021414
SRSF6	0.021304
HSPA1B	0.021300
NRD1	-0.021271
TM4SF18	-0.021249
CIRH1A	0.021162
LSM5	0.021162
RPA3	-0.021037
SUZ12	0.021008
VMP1	-0.020882
UGCG	-0.020880
HSPH1	0.020823
GPX1	0.020798
NDUFAB1	0.020741
TMEM158	0.020740
FAM3C	-0.020728
NSUN2	0.020662
IFI44	0.020629
RPL32	0.020580
SLC44A2	-0.020565
CARM1	-0.020525
RAMP2-AS1	0.020504
FXYD5	-0.020435
ODC1	0.020387
COX7A2	-0.020350
PSMC1	-0.020293
EEF1A1	-0.020289
FAM65A	-0.020272
KPNA4	0.020229
MVB12A	-0.020117
MRGBP	0.020065
SNRPF	0.020055
IFI27	0.020050
BTBD2	-0.020043
DGUOK	-0.020013
HMG20B	-0.019995
DNAJB6	-0.019911
ATP5J2	-0.019910
TTC4	0.019829
POMP	0.019821
PDLIM1	-0.019686
NONO	0.019624
RPL5	-0.019623
MAPRE1	0.019617
MRPS17	0.019551
SSBP1	0.019502
PRDX5	0.019430
DNAJA1	0.019396
RSL24D1	0.019361
RAB5B	-0.019346
PTRF	0.019330
MAP2K1	-0.019315
VPS29	-0.019297
CRABP2	-0.019278
TFRC	0.019246
PPP1CC	0.019241
SUMO3	-0.019212
ZZZ3	0.019192
SF3B5	-0.019164
ANXA3	0.019160
ADSL	0.019137
ROMO1	-0.019086
CLEC2D	0.019046
PABPC4	-0.019031
CCNI	-0.018983
TBK1	0.018974
SLC16A3	-0.018919
ACOX2	0.018918
CD44	0.018897
ATIC	0.018868
ERH	0.018840
UQCRHL	0.018799
EIF5A	-0.018797
MET	0.018792
RFC4	0.018760
SCARNA18	0.018723
YY1	0.018720
LITAF	-0.018676
EIF4H	-0.018668
MSLN	-0.018656
PRDX6	-0.018655
DPP4	0.018649
DNTTIP1	0.018578
EMC7	0.018532
RPP40	0.018506
RAB10	0.018488
PRTFDC1	0.018485
TIMM10	0.018476
EIF3A	0.018406
DIMT1	0.018379
GDI2	0.018368
CNIH4	0.018329
GSTO1	-0.018247
CD81	0.018209
NOP56	0.018209
NGFRAP1	-0.018188
WDR83OS	-0.018176
UFC1	-0.018161
GGA1	0.018158
NDUFB2	-0.018132
YWHAB	0.018042
CHCHD2	-0.018038
KCTD14	-0.018015
SDHD	0.018011
NCAPD2	-0.017930
HCFC1R1	-0.017888
MTCH1	0.017882
RARS	0.017865
MYL6B	-0.017808
RGS2	0.017778
PRSS23	-0.017727
BHLHE40	-0.017718
CCT8	-0.017713
PET100	-0.017686
DNAJC9	0.017658
RPL21P28	0.017653
MRPL19	0.017612
STC2	0.017575
NMRAL1	-0.017564
MICU2	0.017535
CDCA7	0.017420
NDRG1	-0.017415
FAM216A	0.017391
EPDR1	0.017374
CMTM7	-0.017367
PPP1R15A	0.017366
MANF	-0.017304
STRA13	-0.017298
HMGCR	-0.017281
PARK7	0.017278
HDDC2	0.017249
RPL18A	-0.017247
IGBP1	-0.017216
RPS9	0.017128
PIP4K2C	-0.017097
CAMLG	0.017089
ANXA2P1	-0.017076
GRSF1	0.017048
SEC11A	0.017017
AZIN1	0.017016
RANBP1	0.017016
MKRN1	-0.017015
PRPF8	-0.016968
EXOSC3	0.016961
PUS7	0.016957
PMPCB	0.016946
RRP15	0.016932
CHMP1B	-0.016927
GSPT1	0.016900
IFI44L	0.016882
RPA2	0.016880
ACTN4	-0.016872
CCDC58	0.016825
FSCN1	0.016750
TMEM69	-0.016738
WDR75	0.016695
FBL	-0.016685
BABAM1	-0.016630
VAMP8	-0.016614
WBP2	-0.016579
TXNDC9	0.016442
SDPR	-0.016425
FAM50A	-0.016424
FAM177A1	0.016382
SUPT16H	-0.016354
TFAM	0.016322
S100A4	-0.016290
HIBADH	-0.016282
HGS	-0.016235
BAG3	0.016232