!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	Interleukin-1 beta
!ligand_id	Drug Bank ID: BE0001051
!cell_type	embryonic fibroblasts
!organism	mouse
!end_metadata
CCL13	0.369963
CXCL2	0.334149
CXCL6	0.265998
CXCL3	0.262482
EREG	0.194512
NFKBIA	0.156462
TSLP	0.149646
ERRFI1	0.132178
CCL20	0.122446
IER3	0.114937
FAS	0.097034
SMIM3	0.096228
TIMP1	0.094111
IL6	0.090582
IFRD1	0.089747
PTX3	0.088466
TNFAIP6	0.085444
ICAM1	0.082972
RAB32	0.081552
CCRN4L	0.081288
CLIC4	0.078055
IL1RL1	0.075685
HIVEP1	0.066564
NFKBIZ	0.065146
CD44	0.062408
PTGS2	0.060278
ELL2	0.059538
TNFSF11	0.057948
F3	0.057718
VCAM1	0.057255
MMP13	0.057177
SDC4	0.055181
IFITM3	0.054966
GJA1	0.053381
FTH1	0.053040
DSE	0.051772
SLC2A1	0.050441
GJB2	0.050256
EEF1B2	0.049610
AKAP2	0.049596
BTG1	0.049437
RHOJ	0.048923
MMP3	0.048352
STAT5A	0.048277
CH25H	0.047780
NFE2L1	0.047749
HIF1A	0.047030
HK2	0.046134
LITAF	0.045482
LRRC8A	0.044955
OSBPL8	0.044614
DENR	0.044327
PDGFA	0.044269
DTX3L	0.044199
LGALSL	-0.044053
SERTAD4	-0.043630
RIPK2	0.043276
RFFL	0.042915
AKAP12	0.042559
ADAMTS4	0.042069
RAB8B	0.042005
SGK1	0.041888
RASA2	0.040399
BCL10	0.040223
CTPS1	0.040220
LIF	0.040167
WSB1	0.039852
B2M	0.039499
PTGES3	0.039305
PTP4A2	0.039268
GBP4	0.039139
PDPN	0.038952
SPP1	0.038881
ZFP36L1	0.038347
TNFAIP2	0.038027
RAP1B	0.037995
KLF10	0.037200
UAP1	0.036993
SIPA1L2	0.036142
IRS1	-0.036026
TMUB2	-0.035810
KLF6	0.035793
NFKBIE	0.035235
ZNF263	0.035155
CSF1	0.035144
EGR1	0.035099
ST5	0.034813
GADD45A	0.034796
ZC3H12A	0.034466
OLR1	0.034439
THBS1	0.034279
GBP3	0.033880
RALB	0.033751
CPT1A	-0.032971
EIF1AX	0.032327
C9orf72	0.032141
TAPBP	0.032107
PPP1CB	0.031717
DSTN	0.031681
PGRMC2	-0.031388
DHCR7	-0.031376
MARCKSL1	-0.031286
SASH1	0.031030
STX11	0.030891
MMP10	0.030884
SUMO1	0.030756
RGS16	0.030684
SLC39A1	0.030396
FAM84B	0.030162
GBP7	0.030115
ZNF778	0.029906
IL1R1	0.029737
PMP22	-0.029612
GADD45B	0.029610
ADAM19	0.029544
RNF111	0.029458
ACTB	0.029358
DDX3X	0.029231
JADE1	-0.029187
C8orf4	0.029089
SSR3	0.028705
PDZRN3	-0.028304
MAK16	0.028151
FSTL1	0.027976
S100A10	0.027619
CEP170B	-0.027406
FGF7	0.027309
FTL	-0.027249
CCNL1	0.027049
CNN2	-0.026995
RIN2	-0.026992
HADH	-0.026705
PSMD8	0.026613
AMOTL2	0.026529
SOD2	0.026484
PLSCR1	0.026344
DDIT4	0.026330
EDA2R	0.026148
IFITM2	0.025865
SAT1	0.025841
RAPH1	0.025758
RND1	0.025715
FRMD4A	0.025714
CAPN2	-0.025695
KBTBD2	0.025465
HIVEP2	0.025402
PLS3	-0.025394
SH3BGRL	0.025118
RPL7A	0.025018
GAS1	0.024577
CTIF	-0.024563
PXDC1	0.024538
FBXL5	0.024481
SKIL	0.024408
RPL3	0.024165
TXNRD1	0.024008
RND3	0.023921
PPP4R2	0.023910
SMG7	0.023826
TPRG1L	-0.023782
CEP170	0.023711
CALR	0.023652
ETS1	0.023479
MFHAS1	0.023477
SNAI2	-0.023331
TJP1	-0.023089
RRS1	0.023088
FOSL2	0.023086
PCNP	0.023084
RBPJ	0.022962
S100A4	-0.022880
NUPR1	0.022875
PPP1R15B	0.022810
AJUBA	-0.022795
SLCO4A1	0.022794
RNF150	0.022792
GBP2	0.022752
YWHAE	0.022723
HNRNPK	0.022704
FST	0.022678
RHOC	0.022669
RILPL1	-0.022552
PGRMC1	-0.022349
CTGF	0.022232
PKIG	-0.022228
GPBP1	0.022041
SDPR	-0.022022
CASP4	0.022022
JAK2	0.021972
OSMR	0.021890
ZEB1	0.021830
SLC16A1	0.021632
COL6A1	-0.021602
TSC22D2	-0.021548
MAT2A	0.021509
CRIM1	0.021400
MAPK6	0.021336
MBD6	-0.021283
RSL24D1	0.021180
CRYAB	-0.021156
COL4A2	-0.021100
SEPHS2	-0.020988
BHLHE22	0.020962
EIF3E	0.020837
POLR3GL	-0.020792
MECOM	-0.020746
KIAA0247	0.020712
CPNE1	0.020660
LPHN2	-0.020572
TWISTNB	0.020562
WASF1	-0.020511
QRICH1	0.020442
ADAM9	0.020435
SEPT7	0.020434
PTCH1	0.020354
PDGFRB	-0.020252
TMEM123	0.020228
DUSP6	0.020180
TGFB3	-0.020169
NR2F6	-0.019978
RPS28	-0.019937
SMARCD2	-0.019891
TMBIM6	0.019853
PSMA6	0.019769
MEX3B	0.019708
ARL4C	0.019694
MFGE8	-0.019693
MORF4L2	0.019669
CEBPD	0.019654
CSNK1A1	0.019638
DLX2	-0.019551
ABI1	0.019518
YWHAZ	0.019468
ETS2	0.019466
DDX5	0.019459
LGALS1	0.019439
DRAM1	0.019434
MAN1C1	-0.019384
CYP1B1	0.019374
DHRS3	-0.019305
GLIPR2	0.019221
FAM107B	0.019148
SMAD1	0.019110
DPY19L1	0.019074
VGLL3	0.019058
SPRY2	0.018997
HOXC8	-0.018992
MRPS18C	-0.018888
UBE2E2	0.018800
SECISBP2L	0.018755
MYADM	0.018660
CCL5	0.018644
AMMECR1L	0.018617
BACH1	0.018546
CD47	0.018545
PDCD4	-0.018545
VASP	0.018523
EXT1	0.018458
CFLAR	0.018432
ATXN1	0.018420
OAZ1	-0.018361
TSHZ3	-0.018309
TNC	0.018285
PTPN12	0.018201
MSN	0.018168
SKI	-0.018109
TUBA1A	-0.018060
HSPA8	0.018040
CBX6	-0.017972
EIF4A1	0.017929
ATF1	0.017929
TFDP1	0.017862
B4GALT5	0.017822
WISP1	0.017808
PFN2	-0.017777
PPAP2B	0.017772
HNRNPH2	0.017731
STEAP4	0.017728
PPIA	0.017726
CTBP1	-0.017716
AMPD3	0.017699
FLRT2	0.017643
COL3A1	0.017573
HOXD9	-0.017536
SEC24A	0.017494
FOXN2	0.017450
ATP6V0E1	-0.017400
CCDC80	-0.017391
SEC23A	0.017379
FBXO11	0.017365
RPS27A	-0.017341
PBX3	-0.017241
RPS12	0.017241
ESYT2	0.017212
VIM	0.017168
CST3	-0.017152
RPN1	-0.017123
RPL10	0.017118
QTRTD1	0.017099
PHLDA1	0.017070
TIMP3	0.017064
ATP13A3	0.017056
MGP	0.016981
ATF5	-0.016969
NPM1	0.016932
IDI1	-0.016925
GSN	-0.016881
ATP6AP2	-0.016866
HSP90AA1	0.016820
EIF5A	0.016804
NYAP1	-0.016785
SYNPO	-0.016768
TBX3	0.016750
ZFC3H1	-0.016748
DDX21	0.016735
SERPINE1	0.016734
LOX	0.016700
RPS5	0.016672
CDKN1B	-0.016660
LPAR1	0.016598
TM4SF1	0.016535
YBX3	0.016426
DLG3	-0.016415
MYH10	-0.016403
ATP5B	-0.016388
EIF2S3	0.016370
PLK2	0.016321
DKK3	-0.016318
PDGFC	-0.016300
LARGE	-0.016246
CSF2	0.016246
SMIM15	0.016240
TAGLN	0.016237
FLT1	0.016230
PPP2R1A	-0.016206
TPBG	0.016194
ST3GAL5	-0.016172
STMN1	-0.016157
BRK1	-0.016145
NRP2	0.016108
RPL38	0.016104
MYO1H	-0.015979
HSD17B12	0.015902
UBXN2A	0.015883
BMP2K	0.015879
USMG5	-0.015839
ARF4	0.015700
HTRA1	-0.015673
ADPGK	-0.015665
LUM	0.015649
ARL5A	-0.015538
LARP4	0.015489
ACTR2	0.015454
SQSTM1	0.015451
IGF2BP2	0.015443
F2RL1	0.015442
GNA13	0.015366
DAAM1	0.015339
C16orf52	0.015339
CNBP	0.015337
PTPLA	-0.015295
DDR1	0.015270
GPX8	-0.015247
RPL11	0.015217
MAPK1IP1L	0.015170
RERE	-0.015074
PROS1	0.015039
CPEB2	0.015034
RC3H1	0.015018
TGFB2	0.015003
RPL10A	0.014986
ACAT2	-0.014942
ATAD2B	0.014928
NABP1	0.014906
SH3KBP1	0.014901
TNFAIP3	0.014860
PLCB3	0.014859
ACSL4	0.014824
CMPK1	0.014823
GADD45G	-0.014795
LAMP1	-0.014781
EGR2	0.014781
IL6ST	0.014771
H2AFY2	-0.014770
RPS29	-0.014765
MYO10	0.014744
NOTCH2	0.014732
RCAN1	0.014720
ARF6	0.014701
HIST1H1C	-0.014622
BSDC1	0.014616
HOXD13	-0.014552
CERS5	-0.014552
BTG2	0.014538
IL13RA1	0.014527
CRLF1	-0.014474
RBM14	-0.014386
HNRNPH1	0.014343
METTL9	-0.014340
ATP6AP1	-0.014276
C18orf32	-0.014255
TCEB1	0.014253
HEATR5A	-0.014251
NPR3	-0.014183
TNFAIP1	0.014124
ZC3H11A	0.014118
ITPRIPL2	0.014114
TMED2	0.014096
CSNK1G3	0.014035
SLC38A6	-0.014013
EEF2K	-0.014005
CRLS1	0.013935
IQGAP1	0.013928
TCF4	-0.013924
GCSH	-0.013916
ERO1L	0.013916
PSMB7	-0.013903
COL6A2	-0.013901
PNRC1	0.013897
OSTM1	-0.013895
RPL21	0.013881
ZNF281	0.013833
MYL9	-0.013780
ABRACL	-0.013744
ATP5G3	-0.013709
SPSB1	0.013700
MCL1	0.013679
ATP7A	0.013674
PEBP1	-0.013672
P4HB	-0.013663
GNAI3	0.013631
CNST	-0.013613
MYL12B	0.013591
VEGFA	0.013577
KDELR1	-0.013529
HNRNPR	-0.013505
TMED10	-0.013490
ALKBH5	0.013487
MAP4K4	0.013475
PICALM	0.013455
ZNF317	-0.013436
CXXC5	-0.013434
ZNF275	0.013417
SLC25A25	0.013376
NUP85	-0.013367
ROBO1	0.013352
RBM3	0.013340
MCM4	-0.013329
KANK2	-0.013326
SAMD9L	0.013310
PLA2G16	0.013306
MCC	0.013296
TUBB2B	-0.013278
PRDX1	0.013268
ZNRF1	0.013242
CHSY1	0.013241
CPEB4	0.013235
MEX3C	0.013220
MTPN	0.013213
GFPT2	0.013205
FAM101B	-0.013189
AGGF1	0.013169
GPM6B	0.013138
UBE2D3	0.013133
REXO2	-0.013128
PARP12	0.013107
FAM126A	0.013052
VEZF1	0.013029
TRIM8	0.013019
TMEM47	0.012988
YTHDC1	0.012981
ATP6V1D	-0.012971
CYP7B1	0.012945
ANXA2	0.012927
CDC42EP3	-0.012892
MIDN	-0.012879
HOXC4	-0.012862
PAICS	-0.012862
PMEPA1	-0.012783
RPL12	0.012763
HOXD8	-0.012746
RPL13	0.012727
PRKCI	-0.012702
RNASE4	-0.012700
ACVR2A	-0.012700
MMP9	0.012692
KMT2A	0.012675
ACTG1	0.012659
ITSN1	-0.012637
SNX18	0.012635
CASP7	0.012617
HIVEP3	0.012582
CXCL14	-0.012552
MKNK2	-0.012551
TANC1	-0.012547
PDCL	-0.012541
TMEM86A	-0.012530
NBR1	-0.012525
ACTN4	-0.012512
PAN3	0.012511