!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!gene	SIRT1
!cell	Skin
!perturbation	SIRT1 activator, SRT2104
!disease	Psoriasis - 1000mg - 84 days
!end_metadata
PIP	-0.147999
SCGB2A2	-0.122321
KRT73	0.103019
TCN1	-0.095408
DCD	-0.094984
G0S2	-0.092930
NLRP2	-0.092732
RPS4Y1	-0.092468
PLIN1	-0.092399
TSIX	0.091962
PLAT	-0.090202
PLIN4	-0.088384
XIST	0.088103
LPL	-0.084626
SCGB1D2	-0.082450
S100A12	-0.074365
PLA2G2A	-0.072080
HSPB6	-0.069869
KLK6	-0.067565
KDM5D	-0.065389
CPA3	-0.065276
FABP4	-0.065036
KRTAP2-2	0.064416
KRTAP3-3	0.064382
CXCL9	0.062759
KRTAP1-5	0.061272
KRTAP4-2	0.058516
KRTAP3-2	0.058065
KRTAP4-7	0.057424
KRTAP1-1	0.057392
SPRR2C	-0.055418
SLC6A14	-0.054676
KRTAP9-8	0.054545
KRTAP3-1	0.054504
HBB	-0.054282
OR5P2	-0.053363
RBP4	-0.053298
TMPRSS11D	-0.052855
CXCL8	-0.052608
CXCL10	0.052153
KRTAP4-4	0.052057
GPAM	-0.051700
KRTAP4-5	0.050099
KRTAP4-1	0.050012
BST2	-0.049946
KRTAP9-3	0.049858
UPP1	-0.049460
ATP12A	-0.049031
KRTAP4-12	0.049011
PNLIPRP3	-0.048836
NELL2	0.048824
LCN2	-0.047456
KRTAP9-4	0.047409
PADI1	0.046291
PSG4	-0.046269
TLR2	-0.045227
CLEC3A	0.044303
RHCG	-0.043677
CYP4Z2P	-0.043533
MEST	-0.043357
AIM2	0.043295
CHRNA9	0.043192
EIF1AY	-0.043135
FAM118A	-0.042885
SERPINB4	-0.041769
SLC47A2	0.041738
H19	-0.041215
CD14	-0.040950
OR5P3	-0.040865
TSPAN8	-0.040790
CARD18	-0.040671
ALDH5A1	-0.040488
MUCL1	-0.040385
CIDEC	-0.040273
CTSG	-0.040113
TPSB2	-0.040090
ATP1B1	-0.039685
CHL1-AS1	0.038657
LEP	-0.038645
AQP5	-0.038529
DQX1	0.038345
SLC12A2	-0.038344
KRTAP4-3	0.038138
DDX3Y	-0.038031
THRSP	-0.037934
PPP1R1B	-0.037694
SUSD4	-0.036598
SFRP1	-0.036354
LAMP3	-0.036233
NES	-0.036224
MRC1	-0.036189
TRANK1	-0.036178
DNER	-0.035985
KRTAP2-4	0.035915
ADIPOQ	-0.035786
ERAP2	0.035696
ACTA1	0.035606
ZFAT	-0.035424
ARHGAP15	-0.035306
CCL18	-0.035296
SPATA20	-0.035167
PGLYRP4	-0.035158
LOC389834	-0.035040
TPSAB1	-0.034689
ALOX15B	-0.034609
DSG2	-0.034536
SLC44A5	-0.034176
SH3BGRL2	-0.033911
CRYAB	-0.033854
ITM2A	-0.033758
S100A7A	-0.033693
CBLN2	0.033487
GHR	-0.033241
KRTAP4-6	0.033234
IL7R	-0.033196
RHOU	-0.032908
TRPM1	0.032877
LTF	-0.032610
TXLNGY	-0.032529
TEKT4P2	-0.032519
KRTAP2-3	0.032214
FCGR2B	-0.032162
GABRP	-0.032069
CXCR4	-0.032065
F13A1	-0.032037
CLDN10	-0.031687
KRT34	0.031544
TIMM10	-0.031463
FHL1	-0.031456
PCP4L1	-0.031162
RPTOR	0.031106
MEIS2	-0.031050
ZDHHC23	0.031027
PRSS53	0.031005
CA6	-0.030897
CYP2C18	-0.030739
SLC26A2	-0.030667
HOXA2	-0.030659
P2RY14	-0.030502
RAMP2	-0.030440
KRT2	0.030422
SLC23A1	0.030155
SOX9	-0.030063
PRR9	-0.030055
KRT72	0.029992
HARBI1	0.029959
CMTR2	0.029957
RNASE6	-0.029639
ADH1B	-0.029465
PRPF39	0.029379
KRTAP2-1	0.029371
TNNT1	0.029249
BTN3A2	0.029122
TMPRSS4	-0.029066
KCNK5	-0.028858
C2orf40	-0.028843
TMEM116	0.028816
C3	-0.028810
KREMEN2	0.028692
EGFL6	-0.028691
FOLR2	-0.028646
KRT19	-0.028638
NOS3	0.028579
PM20D1	-0.028533
RSAD2	-0.028396
HSD17B2	0.028378
KIF18B	0.028358
PON3	-0.028284
UTY	-0.028280
SERPINA3	-0.028238
ODC1	-0.028141
CPNE2	-0.028027
GP1BA	-0.027905
CCL20	-0.027877
POMZP3	0.027848
CYP4F11	0.027626
MYO5C	-0.027594
DLX3	0.027499
GFRA1	-0.027249
LOC100131564	-0.027196
LRP4	0.027180
DIO2	0.027140
FBXO27	0.027078
NMU	0.027077
PPP1R1A	-0.026910
KCNS3	0.026849
C10orf32	-0.026841
FCGR2A	-0.026798
LOC100132352	-0.026678
FKBP5	-0.026634
ANO8	0.026608
NUDT6	-0.026579
PTGDS	-0.026560
MX2	-0.026524
TVP23C	0.026491
LGR6	0.026382
HS3ST6	0.026382
UGT1A6	0.026141
CYP24A1	0.026029
KRTAP4-8	0.026023
NPL	-0.025993
HOMER2	0.025990
SERPINB3	-0.025984
IL1B	-0.025946
HLA-DQA1	0.025945
ANXA3	-0.025785
IL12RB2	0.025768
PRODH	0.025745
CDK5	0.025645
MAOA	-0.025437
C12orf75	-0.025434
FXYD1	0.025417
UCP2	-0.025309
LOC344887	0.025217
SPC25	0.025213
AOX1	-0.025126
PSG6	-0.025121
PDK4	-0.024973
ATP2A3	-0.024872
ZNF426	-0.024837
MOP-1	0.024833
IL36G	-0.024646
SLC26A9	-0.024634
COMP	0.024546
PSTPIP2	0.024543
C15orf65	0.024507
TRIM73	-0.024413
GZMK	-0.024387
HCG26	0.024369
SAMD9	-0.024338
SNHG5	0.024324
HLA-DQB2	-0.024290
ZBTB16	-0.024200
PSMB9	0.024182
CYP4F12	0.024168
SERPINB13	-0.024162
FXYD5	-0.024081
PRSS27	-0.024027
SLC40A1	-0.024025
TGM5	0.023974
CLSTN2	-0.023901
SVIP	-0.023897
USP9Y	-0.023882
DDX43	-0.023866
SH3KBP1	-0.023761
ACTC1	-0.023716
MGST1	-0.023683
ABCA6	-0.023682
BAALCOS	-0.023661
GNAL	-0.023634
MAPT	0.023606
C7orf60	0.023554
KRT31	0.023533
FZD4	-0.023511
TM6SF1	-0.023505
IGLL3P	-0.023495
XG	0.023494
ZG16B	-0.023444
SRGN	-0.023420
ELOVL3	-0.023407
SELE	0.023366
ZBTB22	0.023366
KRT77	-0.023331
PPT2	0.023321
CYSLTR2	0.023119
GSDMC	0.023055
PITPNM3	0.023045
DLEU1	0.023041
OGN	-0.023041
RGS5	-0.022950
AGTR1	-0.022932
LYVE1	-0.022913
HLA-DPB1	-0.022889
FAM213A	0.022872
CYP1B1	0.022838
APOD	-0.022830
FERMT2	-0.022820
SLC16A14	0.022787
ANKRD20A11P	0.022730
LRG1	-0.022680
FAM83A	-0.022668
C5orf27	0.022629
NETO2	-0.022613
PCSK5	-0.022578
FRAT2	0.022551
PLA2G2F	0.022539
FAM169A	-0.022482
SORBS1	-0.022373
EVI2B	-0.022364
ARL17A	-0.022355
CXCL17	-0.022341
PRICKLE1	-0.022322
HCAR3	0.022321
PSG7	-0.022275
ARHGEF6	-0.022228
CAPN12	-0.022048
RAP1GAP2	0.021996
PRIMA1	-0.021987
SERPINB9	-0.021956
CD163	-0.021928
SMAD1-AS2	-0.021858
KYNU	-0.021840
FLJ41757	-0.021792
AR	-0.021751
AHRR	0.021728
EPCAM	-0.021662
HLA-DQB1	0.021647
ECM1	0.021646
HPGDS	-0.021627
RNF152	-0.021599
CLMP	-0.021571
KRT79	-0.021543
SELP	-0.021469
VNN1	-0.021449
OR2A4	-0.021446
APOL3	0.021446
SRY	-0.021445
STIL	-0.021439
KRTAP4-11	0.021380
ITGB6	-0.021355
MUC20	-0.021352
IL10RA	-0.021338
DKFZP434C153	-0.021272
PLAC8L1	0.021229
IGFBP5	-0.021215
SEMA3G	-0.021122
PALD1	0.021070
FRZB	-0.021050
DPP4	0.021018
CYB561D1	0.020984
RDH16	0.020966
FCGR3B	-0.020941
BEX4	-0.020935
LOC101927164	0.020923
TIFAB	0.020921
CNTNAP3	-0.020919
DEFB4A	-0.020904
KRT33B	0.020883
SMAGP	-0.020879
TBCK	-0.020865
NAMPT	-0.020854
HOXB7	-0.020801
FUT8	-0.020748
AOC3	-0.020733
PSG1	-0.020717
SNX21	0.020619
MFSD4	-0.020599
LINC00842	-0.020570
PCK2	0.020501
TF	-0.020498
CD1B	0.020488
FADS1	-0.020462
E2F6	-0.020360
APLNR	-0.020359
SHANK3	-0.020314
WARS	0.020305
LOC401585	0.020285
SPON2	0.020278
DKFZP586B0319	0.020246
CES1	-0.020226
GNLY	0.020225
NLRP10	-0.020205
LOC100287896	0.020197
RTN1	-0.020191
GNG2	-0.020165
FGFBP2	-0.020146
LRRC37A3	-0.020104
BPGM	0.020097
CD36	-0.020097
KGFLP2	-0.020092
GPLD1	-0.020081
MSX2	0.020071
MS4A6A	-0.020066
C1orf213	0.020016
FLJ46875	0.019949
NPTX2	0.019942
STEAP2	-0.019899
INA	0.019881
LOC154761	0.019875
FMOD	-0.019872
SCGB2A1	-0.019852
SERPINF1	-0.019842
MPZ	-0.019780
HSPBAP1	0.019767
NPFF	0.019764
MAN1A1	-0.019746
INTS2	0.019738
ZFP3	-0.019737
RBP7	-0.019725
WDR5	0.019704
CYYR1	-0.019682
ANKRD20A9P	0.019674
IGFBP6	-0.019671
CECR1	-0.019668
C2orf74	0.019660
TRIP13	-0.019650
COL9A3	0.019646
ZNF516	0.019638
STEAP4	-0.019616
TIMP3	-0.019586
COL15A1	-0.019557
LOC642776	-0.019551
SGCE	-0.019537
MIR22HG	0.019506
RASSF9	0.019475
PNPLA7	0.019469
FADS3	-0.019431
CAPNS1	-0.019390
SFTPD	0.019375
HSPA2	0.019335
LEPR	-0.019309
KRT18	-0.019298
HIF1A	-0.019269
MON1A	0.019266
DHRS9	-0.019260
TGM3	0.019259
COCH	0.019179
KIAA0247	0.019169
AIM1L	0.019168
LYPD6B	0.019166
CHN1	-0.019153
LDHB	-0.019147
RASA4	0.019144
ZBTB34	0.019129
CHRDL1	-0.019121
FAM53B-AS1	0.019060
DAB2	-0.019028
CCL4	0.019012
FAM26F	0.018987
CHST3	-0.018985
SEPT11	-0.018983
NRIP1	-0.018970
KLRB1	-0.018849
KANSL1-AS1	-0.018833
SGPP1	0.018831
KRT27	-0.018779
PDGFD	-0.018777
C15orf48	-0.018766
TICAM1	0.018741
ABCA12	-0.018738
NNMT	-0.018727
CD274	0.018689
GCOM1	0.018664
ULBP2	0.018657
GRIP2	0.018639
ZNF256	-0.018610
MTERF1	0.018597
FAM85A	0.018588
ESAM	-0.018575
AQP7	-0.018565
NUDT2	0.018532
TNFRSF13C	0.018510
KLK8	0.018505
LINC00669	0.018503
RARRES2	-0.018492
CNTN1	0.018486
AXIN2	0.018476
TMC4	-0.018437
PPP1R3B	-0.018423
PLA2G16	-0.018420
IRX2	0.018416
PPARGC1A	-0.018401
NRBP2	-0.018395
XXYLT1	-0.018389
CDON	0.018355
HERC5	-0.018348
PRKAR2B	-0.018343
FAM198B	-0.018318
CEACAM6	-0.018306
MAB21L3	0.018299
LOC642620	0.018277
DOK4	0.018274
REEP1	-0.018272
ANG	0.018268
ERMP1	-0.018263
TMEM52	0.018260
CEACAM19	0.018258
BMP7	0.018239
PI3	-0.018224
MYH14	0.018218
GLYATL2	-0.018213
PLSCR1	-0.018210
TNFRSF10B	0.018194
ASPN	0.018189
CCZ1B	-0.018161
OR5E1P	-0.018145
HLA-DRB4	0.018137
MUC7	-0.018134
NECAP1	0.018043
FAR2	-0.018016
EEF2K	0.017965
LRRN4CL	0.017961
ZNF83	-0.017925
VCAN	-0.017915
ACKR1	-0.017901
COL8A2	0.017877
ALDH1A1	-0.017851
DNAJC15	0.017841
KLK13	-0.017814
SCARNA17	-0.017794