!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Cisplatin
!smiles	N.N.Cl[Pt+2]Cl
!drugbank_id	DB00515
!pubchem_cid	441203
!cell_type	NCI-H460 human lung large cell carcinoma cell line - 24 Hours
!organism	human
!end_metadata
SNORA23	-0.088609
SNORA20	-0.088004
SNORA45A	-0.083435
RNU5B-1	-0.074619
SNORD41	-0.066272
SNORA22	-0.063515
RNU4-1	-0.063146
RNU5F-1	-0.061252
VTRNA1-1	-0.060814
SNORD35A	-0.058060
RNU4ATAC	-0.054436
SNORD116-24	-0.053725
CXCL8	-0.052219
RNU4-2	-0.051615
SCARNA6	-0.050620
RNU5D-1	-0.049289
VTRNA1-3	-0.047522
LOC400590	0.046568
SNORA24	-0.045772
SNORD116-23	-0.045623
HIST3H2A	-0.045241
SNORA49	-0.045116
SNORA68	-0.045063
INTS3	0.044305
SNORD116-11	-0.044290
SNORD60	-0.044179
RPPH1	-0.043332
SNORD116-6	-0.043330
SNORA13	-0.042533
SNORA41	-0.042386
NOP10	-0.042270
RNU5E-1	-0.042168
SNORA7B	-0.041294
SNORD34	-0.041289
SNORD116-1	-0.040662
SCARNA4	-0.039310
SCARNA12	-0.039045
SCARNA10	-0.038282
SNORD46	-0.037988
SNORD116-25	-0.037856
SCARNA5	-0.037493
SNORA52	-0.036944
SNORA80E	-0.036437
HIST1H1D	-0.036145
SNORA71A	-0.036049
SCARNA23	-0.035913
DEFB1	-0.035754
CKS2	-0.035474
SNORD33	-0.034840
HIST1H3J	-0.034822
SNORD13	-0.034802
SNORA71C	-0.034531
HIST1H2BL	-0.034065
OCLM	0.033453
SNORD116-26	-0.033390
SNORD51	-0.033380
SNORD104	-0.033347
TMEM256	-0.033336
SNORA71D	-0.033142
MALAT1	0.033035
ANKRD36BP1	0.032814
SNORD105	-0.032395
SNORD1C	-0.031956
TMEM258	-0.031939
SNORA4	-0.031893
SNORA65	-0.031815
SCARNA22	-0.031581
NDUFB4	-0.031501
PTCH2	-0.031495
SNORA14A	-0.031084
SNORD45A	-0.030830
DUSP1	-0.030805
RNU5A-1	-0.030476
SNORD116-20	-0.029955
USMG5	-0.029829
MTX1	-0.029759
PDCD4	0.029735
SNORA21	-0.029392
NDUFA4	-0.029197
SCARNA16	-0.029163
ZNF487	-0.028963
CKS1B	-0.028947
CYR61	-0.028754
COX7B	-0.028706
SNORD82	-0.028416
ZNF578	-0.028388
SNORD116-16	-0.027791
GGCT	-0.027652
S100P	-0.027331
ZNF737	0.027307
COX17	-0.027269
LOC100506990	0.026764
SNORD116-29	-0.026538
RPS13	-0.026480
PFDN5	-0.026461
SNORA74A	-0.026304
SNORA76A	-0.026200
PAGE2B	-0.026050
UQCRH	-0.025832
PHF5A	-0.025825
ADCY10P1	0.025757
OR4D10	-0.025752
SLC10A5	0.025726
RNU11	-0.025593
HIST1H3A	-0.025532
TIMM8B	-0.025390
MT1G	-0.025383
VTRNA1-2	-0.025367
LINC00216	0.025345
SNORA56	-0.025331
HIST1H1B	-0.025287
TDGF1P3	-0.025260
SEC61G	-0.025104
SCARNA1	-0.025020
SESN1	0.025019
ZNF443	0.024920
SNORD94	-0.024914
SLPI	-0.024822
SNORD113-3	-0.024815
ART4	-0.024751
GCA	0.024678
SNORA57	-0.024635
COX6A1	-0.024633
MRPL50	-0.024406
RMRP	-0.024326
SNORD115-25	0.024299
EIF4A2	-0.024293
BTG2	0.024220
ATP5L	-0.024207
SNORA38B	-0.024194
SCARNA8	-0.024128
TNFRSF12A	-0.023967
SNORD32B	-0.023961
RPL29	-0.023887
MT1A	-0.023738
SNORD102	0.023554
MRPL33	-0.023491
SNORD55	-0.023435
GNGT1	0.023428
OR6C76	-0.023425
C12orf5	0.023361
TP53INP1	0.023283
GZMK	-0.023253
LOC157740	-0.023247
CDR1	0.023220
MMP8	-0.023214
MIR15A	-0.023160
MIR30C2	-0.023063
HIST2H2AC	-0.023059
HSPB1	-0.023038
SESN3	0.023022
SNORD74	-0.023016
SNORD116-12	-0.023015
SNORD115-2	0.022989
DNAJA2	0.022859
TIMM10	-0.022808
SNORA1	-0.022797
PRLHR	-0.022732
SNORD32A	-0.022707
NDUFA2	-0.022697
MIR181B1	-0.022621
C4orf26	-0.022615
NAA38	-0.022562
SNORD13P2	-0.022517
RPL34-AS1	-0.022517
SNORD83B	-0.022509
SNORA28	-0.022498
HILPDA	-0.022459
TIMM8A	-0.022414
EVI5	0.022402
SNORD20	0.022277
SDHD	-0.022231
SNORD14C	-0.022172
GPR22	0.022046
GNG5	-0.022026
SEC61B	-0.021979
TMEM109	-0.021968
NPM3	-0.021941
HIST1H4D	-0.021936
HSP90AA6P	0.021898
SUGT1P1	0.021870
PCDHB4	-0.021849
HIST1H2AH	-0.021845
HIST1H4B	-0.021825
IFT74	0.021784
DOK5	-0.021762
SF3B5	-0.021725
EEF1E1	-0.021702
HIGD2A	-0.021665
ZNF204P	0.021617
LCE2C	-0.021582
SNORD116-13	-0.021571
NOL7	0.021536
ORMDL2	-0.021436
DEPDC4	0.021420
ELOF1	-0.021415
NDUFAF4	-0.021383
DPPA2	0.021368
LCE1B	-0.021353
SNORA75	-0.021343
RNF133	0.021336
DNAJC10	0.021230
CPA6	-0.021227
GPX8	-0.021085
C6orf62	0.021081
DCUN1D1	0.021072
YDJC	-0.021059
NHP2L1	-0.020958
SNORA48	-0.020905
RBMY2EP	0.020846
HIST1H2AC	-0.020820
MPDU1	-0.020785
MIR25	-0.020657
RD3	-0.020654
ADAD1	-0.020608
GCRG224	-0.020543
KLRC4-KLRK1	0.020457
RPS28	-0.020407
ODF2L	0.020400
MIRLET7D	0.020386
PLXNB2	0.020321
LOC101928751	-0.020308
HIST1H1C	-0.020192
MT2A	-0.020169
TRIM50	-0.020157
COX6C	-0.020134
MAP3K2	0.020124
CXorf40B	-0.020113
NDUFA3	-0.020071
HIST1H2BH	-0.020062
RBX1	-0.020036
C14orf2	-0.020020
DSC3	0.019999
LRRC74A	-0.019986
SNORD116-15	-0.019966
DRAM1	0.019945
ZFP36	-0.019877
SNORD4B	-0.019870
LINC00935	-0.019823
MIR186	0.019816
DEFB136	-0.019814
TNP1	-0.019789
MAS1	0.019785
OR2L8	-0.019776
BHMT	-0.019762
TPT1-AS1	0.019692
OR2M5	0.019664
OR5B21	-0.019651
MRPL53	-0.019585
SNORA6	-0.019584
KRT6B	-0.019581
JMY	0.019576
STOML3	-0.019498
GTF2H5	-0.019451
BMPR1A	0.019420
PARG	0.019411
CASD1	0.019386
ATP5E	-0.019362
SNORD15A	-0.019322
POP4	-0.019313
NDUFS3	-0.019293
CYLD	0.019269
COX6B1	-0.019194
CEP170P1	0.019191
RPL36	-0.019176
FLJ40453	-0.019174
MFSD12	-0.019165
HIST1H3H	-0.019145
BCAP31	-0.019140
SNORD12C	-0.019122
DCTPP1	-0.019111
TMEM170A	-0.019075
GJA1	-0.019056
SNORD115-14	0.019031
RAET1L	-0.019003
ANP32E	0.019002
ANKRD32	0.018993
FAM214A	0.018917
TMEM87A	0.018901
SEMA6A	0.018900
SOD1	-0.018899
SNORA37	-0.018897
TMEM261	-0.018891
FAM69C	-0.018873
LAMTOR5	-0.018873
UFM1	-0.018864
WNT10B	-0.018846
UQCR10	-0.018845
SNORD59B	0.018834
NCOR2	0.018832
CPEB2	0.018816
UBE2T	-0.018793
KCNA3	-0.018793
ZNF780A	0.018792
HIST1H2AM	-0.018765
RPL13AP20	-0.018762
COX7A2	-0.018748
MIR1-1	-0.018712
PTMS	0.018700
MIF	-0.018647
LSM2	-0.018621
CPSF4L	0.018614
SNRPB2	-0.018593
UBE2Q2	0.018585
IMPAD1	0.018577
TOP2B	0.018511
EXOSC4	-0.018496
SNORA10	-0.018482
RPS29	-0.018477
C9orf153	-0.018468
SNORD14E	-0.018437
RPS6KA6	0.018429
ERVMER61-1	-0.018420
RPL36AL	-0.018398
RABL3	-0.018350
TMX2	-0.018314
IER3	-0.018309
DCP1B	0.018292
PSMA4	-0.018290
HIST1H2AK	-0.018217
IDO1	-0.018155
GAS6-AS1	0.018152
LOC388022	0.018133
TBC1D8B	0.018128
CUL5	0.018107
ERO1LB	0.018091
MED4	0.018087
PP13	-0.018059
AHCTF1	0.018029
ZNF675	0.018028
HIST1H2AI	-0.018023
OR2T6	-0.018019
ADAM22	0.017974
LIPN	0.017945
CCDC18	0.017944
LOC284788	0.017934
OR13H1	-0.017899
LOC100131581	0.017897
PMCHL1	0.017885
XCL2	0.017881
BHLHA9	-0.017873
LINC00314	0.017867
COX7A2L	-0.017842
MIB1	0.017834
SULT2B1	-0.017829
FERMT1	0.017815
FAM230B	0.017805
HIC1	-0.017795
C15orf61	-0.017779
KDM5B	0.017761
DUSP6	-0.017757
POLH	0.017737
MIR24-2	-0.017719
ARRDC4	0.017708
OR5L2	-0.017696
MICU2	0.017689
BCORP1	-0.017672
UQCR11	-0.017661
CST1	-0.017657
SHC4	0.017650
MRPL20	-0.017635
STAG3L4	-0.017628
NLRP14	-0.017613
DKK1	-0.017606
ARRDC1-AS1	-0.017579
JUNB	-0.017574
OR8H1	-0.017553
STK35	0.017535
CEP19	0.017511
RASA1	0.017457
ZMAT4	0.017446
APRT	-0.017440
CCNB1IP1	-0.017426
KIF20B	0.017415
RBPJ	0.017400
SEPSECS	0.017372
UBA52	-0.017346
FLJ45825	0.017340
MIR208A	-0.017323
PAX8-AS1	-0.017313
ZNF805	0.017306
DDIT3	-0.017299
CDC14B	0.017299
METTL1	-0.017295
HIST1H3I	-0.017278
SLC14A1	-0.017272
IFNK	-0.017263
COMMD9	-0.017261
MRPS24	-0.017255
ANXA2P3	-0.017251
CTSO	0.017250
CDK19	0.017243
ZPBP2	-0.017230
DPM3	-0.017225
SNORD95	-0.017223
DNTT	-0.017212
SMIM7	-0.017194
NDUFS7	-0.017188
DNASE1L3	-0.017187
DBI	-0.017177
LINC00161	-0.017157
APPBP2	0.017154
FFAR2	-0.017153
TTK	0.017149
FAS	0.017148
SPATA5L1	0.017084
TMEM65	0.017073
LINC00851	-0.017072
PTX3	-0.017051
MAP3K19	-0.017040
CDON	0.017028
FAM64A	-0.017028
GCM1	-0.017021
RAB20	-0.017020
CCL23	-0.017007
EMC6	-0.017000
VPS36	0.016995
SNORA29	0.016993
ZNHIT3	-0.016990
HIST1H2BI	-0.016982
MYLIP	0.016961
GBP6	-0.016937
FRG1B	-0.016932
ZNF845	0.016927
ZFP90	0.016921
SNORD116-14	-0.016919
RPL13AP3	-0.016915
LINC00260	-0.016910
HIST1H2AB	-0.016902
COL5A2	0.016889
USP9Y	0.016885
CALCRL	0.016877
RANBP3L	0.016847
PCDHB8	0.016837
IKBKG	-0.016823
ZNF28	0.016817
IFT80	0.016807
KRTAP9-3	-0.016802
MRE11A	0.016788
DYNLT1	-0.016783
SOS2	0.016759
PDCL	0.016758
MBD3L1	-0.016755
WDR4	-0.016753
EEF1B2	-0.016733
LOC100128816	0.016732
HNRNPA1	0.016729
ARL13A	0.016729
MIR135A2	0.016725
DDX60L	0.016709
CTGF	-0.016698
MRPL23	-0.016685
ETAA1	0.016683
SNORD116-21	0.016669
AMPH	-0.016660
LGALS1	-0.016660
PSMB6	-0.016647
ZNHIT6	0.016646
DMXL1	0.016645
OPN5	-0.016642
METTL2A	-0.016642
HIST1H2BM	-0.016610
SERPINB13	-0.016610
GOLGA2P9	-0.016604
GATA3-AS1	-0.016579
COX5B	-0.016571
MIR29B2	0.016570
ACVR2A	0.016563
ARMCX3	0.016561
XAGE5	-0.016553
HEBP1	-0.016550
SAMD9	0.016540
FNDC7	-0.016536
MRGPRD	-0.016531
RPS27	-0.016524
HPCAL1	-0.016508
HIPK3	0.016506
FAM212A	-0.016504
LOC646813	0.016503
FMO6P	-0.016495
MEIG1	-0.016476
DNAJC13	0.016471
SCYL2	0.016471
CLNS1A	-0.016454
BEND5	-0.016429
SNORA5C	-0.016428
TBC1D5	0.016418
TMEM161A	-0.016411
MBL2	0.016407
ZNF252P	0.016405
SPTLC2	0.016401
COQ4	-0.016396
CYB5R4	0.016392
UNC13C	-0.016353
FAM177A1	0.016348
RPS24	-0.016342
AGL	0.016334
SNORD50B	0.016328
KIF11	0.016327
SMARCAD1	0.016314