!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!cell	heart
!perturbation	isocitrate dehydrogenase 2 R172K mutant
!disease	cardiomyopathy
!end_metadata
PDK4	0.286798
ACTA1	0.203099
NMRK2	0.183067
FABP4	0.132764
BAIAP2L1	0.126790
MB	-0.105659
SERINC3	0.100762
ACTC1	-0.097598
SMPX	0.094746
MYOZ2	-0.091980
IFNGR2	-0.090660
ENO3	-0.086757
RGS5	0.085289
MYL7	-0.084001
MYL2	-0.083915
DUSP1	0.082259
TXNIP	0.079366
CD36	0.078814
ACOT2	0.076399
CCNG1	-0.075278
ETFB	-0.072226
COX7A1	-0.071847
CHRM2	-0.071212
HSPA8	0.067838
LRRC10	-0.067783
AQP7	0.067574
ZNF106	-0.067242
TNNI3	-0.067112
CANX	-0.066275
GJA1	-0.065939
COX6A2	-0.064938
TNNT2	-0.063916
ANTXR2	-0.063354
RPL18A	-0.062814
PAM	0.062812
CTSD	-0.062177
CES1	-0.062112
ABCC9	-0.061865
CDKN1A	0.060588
LGALS1	-0.060548
PTP4A3	0.060046
CLU	-0.060028
FHL1	0.059731
NDUFC2	0.059614
NPPA	0.059405
ATP2A2	-0.058395
UCP3	0.058054
BDH1	0.057357
PSME4	-0.056932
FSD2	-0.056779
TACC2	0.056506
GPR56	0.056363
CACNA2D1	-0.055170
OGN	-0.054837
ADSSL1	0.054626
SPARCL1	0.054508
BNIP3	0.054384
HSP90AB1	-0.053542
COMT	0.052820
RPLP0	-0.052442
CASQ1	-0.052330
NDUFB6	0.051568
GOT1	0.051460
DES	-0.051170
RPL3L	-0.050862
MDH2	-0.050719
FAM214A	0.050411
TMEM50B	-0.049164
XIRP2	0.048948
SNRK	0.048619
ZBTB16	0.048134
IVD	-0.047704
SDHD	0.047617
ELTD1	0.047396
PICALM	0.046976
HSPA5	-0.046953
GSTK1	-0.046354
CLIP4	-0.046338
GAPDH	0.046250
SLC43A3	0.046172
APOLD1	0.045921
SLC25A5	0.045652
C10orf10	0.045320
CDH5	0.045203
ATP1A2	-0.045046
NDUFB9	-0.044895
CDH2	-0.044671
HFE2	-0.044651
TTN	-0.044570
CSRP3	-0.044544
CHPT1	-0.044495
PPP2CA	0.044097
CA4	0.044015
CD81	-0.043967
APOBEC2	-0.043770
GPR116	0.043444
IGFBP7	0.043014
ACSL1	0.042896
RHOA	0.042626
EIF4G2	-0.042607
DPT	-0.042567
RYR2	-0.042407
NAMPT	-0.042337
FITM1	-0.042012
PIK3R1	-0.041866
ACTN2	0.041352
SPARC	0.040755
DCN	-0.040476
LCLAT1	-0.040386
SLC16A1	-0.040112
ALDOA	0.039997
EEF1A1	0.039893
ACTA2	0.039299
MEF2A	-0.039218
TIMP4	0.039144
SUMO2	-0.038811
ANKRD1	0.038523
IDH2	-0.038431
HSD17B11	0.038385
HSP90B1	-0.038375
MAT2A	-0.038284
TP53INP1	0.038103
LBH	-0.037923
GABARAPL1	0.037616
UGP2	0.037550
CPT1A	0.037504
SH3RF2	-0.037413
SSPN	-0.037350
IL13RA1	-0.037310
GHR	-0.037258
CRAT	-0.037229
ABLIM1	0.037184
FASTK	-0.037117
ESAM	0.037097
EGLN1	-0.036801
YIPF7	-0.036746
PGAM2	0.036737
CS	-0.036693
KLHL38	0.036563
ATF3	-0.036494
AS3MT	-0.036304
ACADM	-0.036177
COX20	-0.036118
BLOC1S1	-0.036103
SRL	0.035442
SORD	-0.035345
MUT	-0.035329
SNAP23	-0.035217
PCDH7	-0.035179
FLNC	0.034841
UCP2	0.034711
CSDE1	-0.034389
IDH3G	-0.034049
PYGM	-0.033946
CDK2AP1	-0.033594
KCNJ3	-0.033462
CAMK2D	-0.033343
HIPK1	0.033308
TFPI	-0.033236
RBM3	0.033122
GLUL	0.032883
ISCA1	-0.032859
GPI	0.032605
CLDN5	0.032487
CORIN	-0.032475
FKBP5	0.032418
PHB2	0.032385
POLR2F	-0.032345
ASB14	-0.032211
LMOD2	0.032044
CD300LG	0.032028
ATP5G3	0.031839
ASB15	-0.031766
HOPX	-0.031682
NDUFV1	-0.031569
PNPLA2	0.031522
UBE2D3	-0.031441
NDRG2	-0.031430
CREG1	-0.031292
MYOM1	0.031262
UBC	-0.030992
PFKM	-0.030932
GSTP1	-0.030725
REEP5	-0.030173
TUBA1B	-0.030071
DYNLRB1	-0.030059
ECHS1	-0.029972
RPS20	-0.029962
LPL	-0.029944
TMEM65	-0.029852
MYBPC3	-0.029679
FAM117B	0.029625
RPL10A	-0.029613
HMGCS2	0.029600
PPT1	-0.029402
CRIP1	-0.029401
DUSP7	-0.029379
SYNGR2	-0.029350
PLBD1	-0.029341
DDIT4	0.029310
DHDH	-0.029247
LMAN2	-0.029073
SMIM20	-0.029010
PPIF	-0.029009
ANGPTL2	-0.028946
SUCLA2	0.028887
USMG5	-0.028886
PFKFB2	-0.028808
TP53I11	0.028788
MPV17	-0.028769
FXYD5	0.028724
IDH3A	0.028665
SDHC	-0.028638
SGCB	-0.028597
CALR	-0.028520
AQP6	0.028263
CHCHD3	-0.028018
NDUFB4	-0.027955
DPEP1	0.027831
CCDC141	-0.027753
FBXO32	0.027610
DSP	-0.027606
GPC1	-0.027591
ATP6V1B2	0.027579
ENO1	0.027531
SPTAN1	0.027465
COX7B	-0.027459
PKP4	0.027445
NUAK1	-0.027391
LDB3	0.027382
PHYH	-0.027232
HHATL	-0.027194
KCNJ5	-0.027091
WFS1	-0.026975
UCK2	0.026963
HADHA	0.026926
C10orf107	-0.026881
YBX1	-0.026724
AKR1B1	-0.026599
LAMP1	-0.026530
NFKBIA	0.026400
TCN2	0.026344
RGCC	0.026165
MID1IP1	-0.026121
GID4	-0.026032
DBT	-0.025984
IDH3B	-0.025942
SESN1	0.025935
ART3	-0.025928
CYYR1	0.025864
UQCRQ	-0.025788
ATP5C1	-0.025787
GPAM	0.025787
PPP1R3C	0.025731
LRRC8C	0.025728
NEXN	-0.025688
ADPRHL1	-0.025666
GBAS	-0.025652
SLC2A4	-0.025599
CTGF	0.025597
FH	-0.025562
ATG10	-0.025557
MYOCD	-0.025496
SAMM50	-0.025475
ACTG1	-0.025455
MSRB1	0.025402
RPL18	-0.025396
PALLD	-0.025342
MIF	0.025330
TMEM160	-0.025308
GRM1	-0.025274
WNK1	-0.025262
NDUFA4	0.025252
TMEM182	-0.025221
MRPS21	-0.025156
YAE1D1	-0.025136
PPP2R3A	-0.024981
ATG13	0.024971
BTNL9	0.024889
TXN	-0.024822
SLC25A20	0.024774
ASNSD1	-0.024725
OTUD1	-0.024677
LMOD3	-0.024668
CAPNS1	-0.024596
GNA12	-0.024591
CYB5A	-0.024492
FYCO1	-0.024491
NDRG4	0.024444
ATP5H	-0.024394
ISOC1	-0.024345
RFK	-0.024334
RALGAPA2	-0.024245
ALAS1	0.024221
B2M	-0.024210
TECRL	0.024195
HSPB7	0.024187
BGN	0.024170
NDUFB5	-0.024140
NDUFS6	-0.024117
CKMT2	0.024046
PINK1	-0.024018
HSPB8	-0.023979
HDLBP	-0.023951
ACER2	0.023903
PRKAR1A	0.023735
LAMB2	-0.023669
CD164	-0.023611
EEF1A2	-0.023586
LMO7	0.023573
FBLN1	-0.023550
JUN	-0.023508
PARK7	0.023464
DGAT2	-0.023460
PTPRB	0.023304
HSPA9	0.023245
RAB10	-0.023088
AES	-0.023044
RPS6	-0.023014
NEO1	-0.023001
HSPB6	-0.022885
ANKH	-0.022876
NDUFS4	0.022872
GSN	-0.022824
BCHE	-0.022715
SGCA	-0.022701
TXLNB	-0.022642
ANAPC13	-0.022559
MPI	0.022541
RBPMS	0.022367
ARL8A	0.022307
PSMB3	-0.022192
BCAM	0.022173
FMO1	-0.022162
MCCC1	0.021991
PKIA	-0.021959
PPP1R14C	-0.021911
TMX4	-0.021903
MYL3	0.021889
ADAMTS9	0.021870
FBXO44	0.021761
RBM24	-0.021676
SAR1B	0.021611
LPCAT3	0.021503
MRPL3	0.021462
UQCR11	-0.021433
ENTPD4	-0.021419
SORBS2	0.021246
RARB	-0.021182
RPS26	-0.021167
VPS25	0.021087
LRRC39	-0.021069
KDR	0.021031
PGK1	0.020952
RPS15	-0.020862
MYL1	-0.020822
C3	-0.020800
TECR	0.020787
EPAS1	0.020754
ALDH2	-0.020752
CA3	-0.020716
YWHAE	-0.020698
TMX2	-0.020685
TANGO2	-0.020672
ARL2BP	0.020657
GSTM1	-0.020579
LRTM1	-0.020568
TMOD4	-0.020520
RPS5	-0.020486
CAT	0.020474
CD93	0.020404
HAGH	0.020220
LAPTM4A	-0.020216
TINAGL1	0.020146
LRRC8A	0.020124
CAP2	-0.020112
NDUFAF1	0.020093
ANXA5	0.020015
CLYBL	-0.019962
LAMP2	-0.019928
ACADSB	-0.019918
NRD1	-0.019907
TSPAN3	0.019853
SLC6A8	-0.019822
AGTPBP1	-0.019775
NDUFB11	-0.019768
KLHL41	-0.019765
SLC25A12	-0.019704
MGLL	0.019703
ATP5J2	-0.019685
ADH1C	0.019619
ARL1	-0.019596
SPTBN1	0.019564
TMEM126A	-0.019555
BCAT2	-0.019537
PDHB	0.019498
RAB2A	-0.019468
KDELR1	0.019449
RPL12	-0.019447
RHOJ	0.019447
MYLK3	-0.019425
ABRA	0.019417
RBM20	-0.019416
SERPINE1	0.019373
GABARAP	-0.019367
FDFT1	0.019343
HNRNPU	-0.019331
NDUFS1	-0.019320
EHD4	0.019288
MYOT	0.019252
APOE	-0.019220
CLASP1	-0.019168
SGK1	0.019128
MAOB	-0.019104
DAG1	-0.019101
UQCC2	-0.019082
TSPAN7	0.019074
BVES	-0.019062
MAPKAPK2	0.018989
EGLN3	0.018974
SLC44A2	-0.018970
FAM134B	0.018908
MBNL2	0.018890
LDHA	-0.018832
FAU	-0.018801
COQ3	0.018799
KCNG2	-0.018773
PIM3	0.018769
BOD1	-0.018692
SLC20A2	-0.018675
MFAP5	0.018655
GAS6	-0.018649
CTSC	-0.018644
DHRS11	0.018538
PSMD7	-0.018512
NDUFB8	-0.018433
STARD10	-0.018406
ACTB	-0.018400
MYH7	-0.018277
SCN5A	-0.018277
PDLIM5	0.018275
CD34	0.018221
MCEE	-0.018219
KLHL24	0.018153
PRKRIR	-0.018148
GNPAT	-0.018140
ARHGAP20	0.018127
COX18	0.018122
TMBIM1	0.018107
BTG2	0.018096
XDH	0.018079
NAA20	-0.018076
EPB41	0.018054
SRI	0.018054
SDCBP	0.018031
C1QBP	0.018020
POR	0.018012
RAB21	-0.017979
HNRNPA2B1	-0.017943
TIMP3	0.017934
LPIN1	-0.017925
GPR22	-0.017914
FUCA2	-0.017904
FAM96A	-0.017899
KIF5B	-0.017895
VEGFA	-0.017858
LY6E	0.017847
FABP3	0.017831
LSMEM1	-0.017822
TRIM63	-0.017821
ALDH1A1	0.017793
ETFDH	0.017720
HIPK2	-0.017687
RPL5	-0.017682
PFKFB1	0.017650
ASB2	-0.017626
IL6ST	-0.017625
ECHDC2	-0.017587
UQCRB	0.017571
S100A1	-0.017538
DHRS1	0.017532
PLA2G5	-0.017525
CUTA	-0.017508
S1PR1	0.017497
ACAT1	-0.017496
IMMT	-0.017431
CDH13	-0.017396
QKI	-0.017336
PHKA1	0.017330
CLIC5	0.017323
CDS2	0.017277
ATP5G2	-0.017242
SFPQ	-0.017239
CST3	-0.017235
MRPL15	0.017211
POLDIP2	0.017205
DDX5	-0.017187
PERP	0.017154
LDHB	-0.017113
TRIM55	-0.017109