!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	calcitriol
!smiles	CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
!pubchem_cid	5280453
!cell_type	Macrophages
!organism	human
!end_metadata
CYP24A1	0.167146
FBP1	0.113302
DPP4	0.098666
TREM1	0.081166
SEMA3C	0.079576
CD14	0.076899
CYP19A1	0.069607
CXCL8	0.065226
CLMN	0.064074
PEX5L	0.062406
FN1	0.060536
NAV3	0.060355
SHE	0.055922
ANKRD22	0.055383
G0S2	0.054053
SLC7A2	0.053262
CX3CR1	-0.052365
IL1B	0.052005
EFTUD1	0.051462
FER1L6	0.051045
FAM111B	-0.050236
SULT1C2	0.050133
ADAMDEC1	0.050132
SYCP2	0.049936
AQP9	0.049718
GEM	0.049364
NUDT4	0.049186
STATH	0.049081
ADAM28	0.048445
CEMIP	0.048188
CD180	-0.048148
SLC16A6	0.048009
HS3ST3B1	0.047692
DEPTOR	-0.046778
TSPAN18	0.045883
CLEC5A	0.045436
THBD	0.045146
SMPDL3A	0.045057
SAT1	0.044949
HSD11B1	0.044715
CCNE2	-0.044476
ABCD2	0.044399
APBB3	0.044365
TDO2	0.043635
C3orf52	0.043608
EXT1	0.043286
TNFSF15	0.043261
SULF2	0.042691
VCAN	-0.042072
GABRG2	0.041946
NTM	0.041532
MAPK13	0.040166
ITGB8	0.039943
DENND6B	0.039770
CD226	0.039186
LOXHD1	0.039157
E2F8	-0.038555
GLDN	0.038234
CMYA5	0.038189
MMP8	0.038172
CDC6	-0.038161
TLR7	-0.037965
SEMA6B	0.037697
TMEM156	0.037578
DLGAP1-AS1	0.037568
EGR2	0.037528
F13A1	-0.037516
WDR76	-0.037437
TMEM37	0.037257
GNLY	0.037256
UBASH3B	0.037137
C3AR1	-0.037121
HBEGF	0.036911
PDCD1LG2	0.036764
CPM	0.036763
BIN1	-0.036649
BRIP1	-0.036647
DTL	-0.036381
CENPI	-0.036363
MS4A4A	-0.036210
GCNT1	-0.035706
CAMP	0.035632
CDCA7	-0.035629
NEK10	0.035478
EXO1	-0.035471
CD274	0.035378
CLSPN	-0.035371
TDRD10	0.035296
ORC1	-0.035271
CENPU	-0.035004
STS	0.034974
MYBL1	-0.034722
ACVR1B	0.034622
PPARGC1B	0.034584
SLA	-0.034304
TLE1	-0.033952
KIT	-0.033944
HEG1	-0.033937
CACNB4	-0.033686
NCF2	0.033667
CDC45	-0.033648
CDA	0.033538
ACSL1	0.033370
LRP12	0.033230
THEMIS2	0.033076
PDLIM4	0.032877
LRP1	0.032785
TYMS	-0.032685
ATP10A	-0.032622
RAD51	-0.032508
PFKFB4	0.032287
LGMN	0.032275
CHAF1B	-0.032214
ELL2	0.032196
GALNT12	-0.032063
ESCO2	-0.031997
NID1	-0.031987
SPC25	-0.031952
ASF1B	-0.031844
PRR5L	-0.031831
FADS2	-0.031710
DCSTAMP	0.031596
KLRC4	-0.031564
ADCY8	0.031522
PARM1	-0.031414
BBOX1	-0.031278
FBXO5	-0.031192
INA	-0.031182
DSCC1	-0.031178
PCDH9	0.031089
ADAMTS1	0.031029
XK	-0.030919
MCM8	-0.030884
FGL2	-0.030883
BLM	-0.030647
BRCA2	-0.030635
ARNT2	0.030589
SERPINI1	-0.030487
MPEG1	-0.030283
ZNF385D	0.030182
CCL20	0.030167
RTTN	-0.030163
TESPA1	0.030163
CDK2	-0.030108
MCM6	-0.030014
E2F7	-0.029908
CECR1	0.029847
NEIL3	-0.029769
CDCA7L	-0.029739
FEN1	-0.029679
CDC7	-0.029565
BRCA1	-0.029554
HK2	0.029535
IGFBP3	0.029378
TMEM45A	0.029315
KIAA0101	-0.029307
MKI67	-0.029152
SLFN13	-0.029112
MMS22L	-0.029046
RFC4	-0.028937
FAM86DP	0.028777
CFLAR	0.028768
RAD51AP1	-0.028745
HAL	0.028701
LRMP	-0.028665
ATAD2	-0.028660
LANCL3	-0.028655
SERINC2	0.028655
KIF11	-0.028560
ZNF367	-0.028487
MYB	-0.028466
DSN1	-0.028387
SKA1	-0.028182
XRCC2	-0.028172
KIFC1	-0.028154
CIT	-0.028131
EPAS1	0.028010
FOXM1	-0.027976
CD38	0.027956
GINS1	-0.027924
ANLN	-0.027841
HELLS	-0.027765
NCAPH	-0.027673
TMEM106C	-0.027634
SERPINE2	0.027578
MELK	-0.027498
USP2	0.027441
PIP5K1B	0.027389
KIF2C	-0.027372
CASC5	-0.027365
SLC8A1	-0.027362
TAF9B	-0.027295
FAM159B	0.027223
MCM2	-0.027089
RAD54B	-0.027059
FANCD2	-0.027001
PLK4	-0.026998
SLC22A4	0.026995
C1orf112	-0.026991
WDHD1	-0.026960
MBOAT2	-0.026947
MCM5	-0.026870
SPOCK1	0.026852
TIMELESS	-0.026840
USP18	-0.026810
KIF15	-0.026736
RBBP8	-0.026729
CD52	0.026695
UCP2	-0.026676
CDK1	-0.026670
SMC1B	-0.026668
ASAP2	0.026663
C18orf54	-0.026621
PSMC3IP	-0.026545
NCAPG2	-0.026503
ZGRF1	-0.026474
FERMT2	-0.026449
BCL2	0.026423
P2RX7	0.026343
SHCBP1	-0.026318
ATAD5	-0.026296
MYO1G	-0.026228
KIF4A	-0.026127
NFATC2	-0.026105
MCM10	-0.026089
MGAM	0.026083
CDCA2	-0.026066
CENPK	-0.026046
TGM2	0.026045
GINS2	-0.026043
DIAPH3	-0.025993
CHST15	0.025915
RAD54L	-0.025851
PRC1	-0.025829
TTF2	-0.025822
DPF3	0.025820
CEP128	-0.025815
ANKRD36	-0.025788
TICRR	-0.025771
PAK1	-0.025757
ROS1	0.025682
LOC81691	-0.025651
HVCN1	-0.025646
PRIM1	-0.025631
ADCY1	0.025561
C5	-0.025552
MCM4	-0.025502
EMP3	-0.025479
FAM102B	-0.025476
CTSV	-0.025472
POLA2	-0.025443
HIST1H2AJ	-0.025427
STIL	-0.025382
FANCI	-0.025349
CEP55	-0.025344
NDC80	-0.025340
LPGAT1	0.025320
CDCA5	-0.025303
ERCC6L	-0.025264
TNFAIP6	0.025240
FLNB	-0.025190
GPR141	-0.025168
ALOX5	0.025150
MSH6	-0.025142
FANCC	-0.025104
MYBL2	-0.025099
SMC6	-0.025072
MCM3	-0.025056
KIAA1841	-0.025047
ZNF443	-0.025029
MCM7	-0.025024
BHLHE41	0.025003
KDELC2	-0.024959
DDX26B	0.024914
MYC	0.024829
STXBP5L	-0.024775
ZWINT	-0.024719
MARCH1	-0.024717
CCDC15	-0.024711
CHEK1	-0.024681
CDKN3	-0.024661
TACC3	-0.024654
CD300A	-0.024644
CRISPLD2	0.024610
FIGNL1	-0.024533
POLE	-0.024532
HMCN1	0.024522
KNTC1	-0.024502
BANK1	-0.024496
CKAP2	-0.024443
MATN2	-0.024405
IL7R	-0.024376
RPL39L	-0.024364
IFNGR1	-0.024323
BCAT1	0.024314
AREG	0.024310
PRKCH	0.024309
RTKN2	-0.024266
CEP78	-0.024264
FADS1	-0.024243
ESYT1	-0.024194
POLA1	-0.024183
SPC24	-0.024180
LMNB1	-0.024169
C5orf34	-0.024119
GPR65	0.024090
NDUFAF4	0.024077
NUF2	-0.024074
RFC2	-0.024052
FANCA	-0.024035
MGAT5	-0.024023
GJC1	-0.023982
PRICKLE1	0.023974
MSH2	-0.023963
FAM217B	0.023945
ORM1	0.023908
AGPAT4	0.023849
KATNAL1	-0.023834
ORC6	-0.023829
SEPP1	0.023778
SMC2	-0.023749
POLQ	-0.023710
DONSON	-0.023648
SLC4A7	0.023647
POLE2	-0.023637
UBE2T	-0.023614
OXCT1	-0.023525
BCL2A1	0.023484
RIBC2	-0.023484
SLC2A5	-0.023454
HJURP	-0.023448
DAAM1	0.023401
CLSTN2	-0.023389
PPFIA2	0.023331
HMGB3	0.023222
CCDC14	-0.023139
ITGAM	0.023117
GRK5	0.023092
DLGAP5	-0.023073
LTA4H	0.023065
GMNN	-0.023026
KCND2	0.023000
ITGA7	-0.022999
LRRCC1	-0.022968
CCNE1	-0.022956
PLP2	-0.022912
IGSF6	-0.022882
RFC5	-0.022859
SRA1	0.022787
LMO7	-0.022694
CCR1	0.022685
BVES	-0.022659
TTC39B	0.022611
APOO	0.022590
GINS4	-0.022569
CDKN2C	-0.022546
ITGB3BP	-0.022546
PRR11	-0.022470
FLT3	-0.022450
TTC14	0.022441
DDB2	-0.022426
DEPDC1B	-0.022409
NUSAP1	-0.022385
EMP2	-0.022385
GEN1	-0.022370
DCLRE1B	-0.022354
CKAP2L	-0.022333
CCNA2	-0.022300
LGALS9	0.022298
SLC15A2	-0.022274
ANXA6	-0.022227
CSPG4	-0.022195
COX7B	0.022180
CENPF	-0.022168
RFC3	-0.022148
ZNF589	0.022123
STRIP2	-0.022106
NFKBIA	0.022084
GGH	-0.022079
PHF19	-0.022068
ZNF281	0.022052
RACGAP1	-0.022022
HCK	-0.021957
ARSG	0.021917
PTPN14	-0.021902
TCP11L2	0.021887
GNG11	0.021878
SGOL1	-0.021866
SLCO3A1	-0.021831
CNTN4	-0.021831
CDC25A	-0.021828
RMI1	-0.021826
ZNF695	-0.021816
BUB1	-0.021772
DECR1	0.021766
SLC12A8	-0.021692
TTK	-0.021690
SPIN4	-0.021675
CCNF	-0.021645
KANK2	-0.021628
TK1	-0.021620
TEAD1	0.021596
SP100	0.021554
ATP1B1	-0.021550
GPSM2	-0.021521
RRM2	-0.021519
ZFAND4	0.021487
EZH2	-0.021459
GINS3	-0.021458
FANCB	-0.021420
HIST2H2AB	-0.021361
SEMA7A	0.021349
CPT1A	-0.021335
RRM1	-0.021321
CXorf21	-0.021289
DHRS9	-0.021287
NEO1	0.021265
FASTKD1	0.021163
GAS6	-0.021158
CYBRD1	-0.021149
SMYD3	-0.021142
POLH	-0.021135
DDIT4L	0.021129
TLR2	0.021106
CASP8AP2	-0.021100
KLF4	-0.021097
DUSP27	-0.021090
PARP2	-0.021062
CD1C	-0.021027
MTBP	-0.020976
EME1	-0.020958
FAM162A	0.020957
RNASEH2A	-0.020951
MRAS	0.020934
PGBD5	0.020880
TSPAN2	-0.020878
LOC1720	-0.020825
CEBPB	0.020814
CYBB	-0.020760
MCOLN2	-0.020750
SCIN	-0.020744
EMR1	-0.020726
PLSCR4	-0.020724
FN3KRP	-0.020724
E2F2	-0.020704
BCL2L11	0.020697
KIF23	-0.020666
CPEB4	0.020663
TMEM97	-0.020640
CNN2	-0.020631
TPX2	-0.020625
FANCG	-0.020588
FAM135A	0.020585
CCL28	-0.020584
MASTL	-0.020541
NWD1	0.020530
RAI14	0.020514
TRIP13	-0.020497
CEP57L1	-0.020495
SYTL3	0.020490
PRKAR2B	-0.020477
ITM2C	-0.020450
SORL1	-0.020429
RFWD3	-0.020418
LIG1	-0.020400
CPED1	-0.020400
ZBTB20	0.020390
FAM198B	0.020360
CENPQ	-0.020349
ICAM1	0.020341
UBR7	-0.020316
KLHL4	0.020297
PLD1	-0.020289
SNX24	-0.020279
FANCL	-0.020269
CR1	0.020266
TIPIN	-0.020265
DYSF	0.020264
UNG	-0.020252
NINJ1	0.020240
PBK	-0.020234
BRI3BP	-0.020214
GTSE1	-0.020174
RAB23	-0.020165
WEE1	-0.020098
TRPM8	0.020092
SLC11A1	0.020022
CENPE	-0.019991
CHAF1A	-0.019942
CCSAP	-0.019894
NLRP12	0.019866
KCNMB1	-0.019858
DCAF12L1	-0.019846
TOP2A	-0.019844
C1orf21	-0.019838
PDK4	-0.019800
MTF1	0.019785
BLVRA	-0.019782
NDST3	0.019781
BTG3	-0.019741