!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Folic Acid
!smiles	C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N
!drugbank_id	DB00158
!pubchem_cid	6037
!cell_type	NA
!organism	human
!end_metadata
RPS4Y1	-0.064804
IFI27	-0.053165
HLA-DQA1	0.050601
HLA-DRB5	0.047247
CCL18	-0.046515
CHST13	-0.045841
CCL13	-0.044898
SERPINF1	-0.044731
S100A10	-0.044224
TFRC	0.043530
SPATC1L	0.042894
GRINA	0.042475
IL18RAP	0.041519
RPL14	-0.041337
HLA-G	-0.041319
NMNAT1	-0.040536
TRAPPC1	0.040326
POLH	-0.040201
IFI6	-0.040125
JOSD2	0.038931
HLA-DRB3	-0.038814
ZNF580	0.038365
RPL37	-0.038357
SPATA20	-0.038279
STAT6	-0.038086
TMEM156	-0.038031
IFI27L2	-0.037321
BLZF1	-0.037259
NXPE2	-0.036234
GINS1	-0.035060
CXCL8	0.034783
FGR	0.034749
IGSF6	0.034607
HCFC1R1	0.034381
INTS7	-0.034302
CRIP1	-0.034096
RPS26	-0.034002
TPM4	0.033955
CEBPD	0.033687
CD52	-0.033380
RPL27A	-0.033282
CD27	-0.033108
LIME1	-0.033036
C7orf43	0.033004
LY75	-0.032990
HLA-A	-0.032414
CFL1	0.032352
SLC43A2	-0.032010
CCL2	0.031903
PCDHB9	-0.031803
EIF5A	0.031775
PTER	0.031542
AZU1	0.031536
MAPK8IP1	0.031509
STMN3	-0.031443
CCR5	0.031287
N4BP2	-0.031111
CERS6	0.031006
HVCN1	-0.030915
KRCC1	0.030894
CARD9	-0.030576
CD163L1	-0.030494
ZNF620	-0.030460
SEC61A1	-0.030333
KLF2	-0.030193
FAM73A	-0.030087
PDPN	-0.029897
S1PR4	-0.029863
SGSH	0.029639
DEFA4	0.029557
SEMA4A	-0.029430
ARRB2	-0.029392
CXCL10	0.029319
BRK1	-0.029249
POLK	-0.029114
HLA-DRB1	-0.029087
RAB3IL1	-0.029079
SAFB2	0.029045
MCU	-0.028958
LYRM7	-0.028716
LAT	-0.028671
C1QC	0.028661
PPP6R1	-0.028658
PLIN2	0.028603
WDR59	0.028489
CYP4F3	-0.028435
RPS29	-0.028370
A2M	-0.027993
HAUS2	-0.027931
PRMT2	0.027858
IL18R1	0.027853
KLF9	0.027845
TCF7	-0.027787
RPS17	-0.027666
LIMS1	0.027498
ZNF790	-0.027490
SASH1	0.027463
PPP2R3B	-0.027455
TRMT112	-0.027423
TSPAN4	-0.027382
NPIPA1	0.027244
FAM134C	-0.027182
RPL37A	-0.027092
ALPP	-0.027050
TRIM74	-0.026908
CD300C	-0.026868
SLC29A1	0.026859
LDLRAP1	-0.026767
PPP4C	0.026724
PDK4	0.026652
UBL5	-0.026606
MRPS7	-0.026553
TNFRSF1A	-0.026406
FAM213B	-0.026380
LYRM4	-0.026364
EMILIN2	-0.026324
CLDN23	0.026280
RBM4	-0.026240
MRPL17	-0.026232
CES1	-0.026148
CSAD	-0.026138
DAPP1	-0.026096
PDDC1	-0.026076
PLCG1	-0.025977
EVI5	-0.025970
UBXN10	0.025900
TUBB2A	0.025896
CTSK	-0.025880
TMEM258	-0.025750
SLC14A1	-0.025731
SKAP1	-0.025453
MATN3	-0.025444
NCL	-0.025416
CXCL9	0.025383
TREM2	-0.025292
MAGEB10	-0.025276
TNFRSF25	-0.025267
SYNGR2	-0.025207
APOBEC3C	-0.025203
TMA7	-0.025161
RPS5	-0.025127
CCAR1	0.025043
WDR82	-0.024924
BCL2A1	0.024910
SQSTM1	-0.024895
MMP17	0.024876
IFITM3	-0.024853
HMOX1	-0.024785
NOTCH1	-0.024696
ZNF652	-0.024669
SEPT7	-0.024615
PRPF19	-0.024615
NUPR1	-0.024587
ISG20	-0.024539
ROCK1	0.024529
SLC9A3R1	-0.024521
RPL23	-0.024450
IRF3	0.024443
OTUB1	0.024437
UCP2	0.024381
LRP5	0.024375
TUBA3C	-0.024315
IL2RG	0.024314
ITCH	-0.024262
HAMP	0.024241
LILRA3	0.024195
ID3	-0.024178
KLHDC3	-0.024098
GAL3ST4	-0.024041
ANKDD1A	0.024030
FN3K	0.023948
LHPP	-0.023926
KRTCAP2	-0.023915
XBP1	-0.023858
PNP	-0.023843
CD300LF	0.023819
CHD8	-0.023744
DSN1	-0.023681
IGJ	0.023663
MRPS6	0.023656
RNF19B	0.023640
COL23A1	-0.023640
FABP3	-0.023637
EML3	0.023626
CEP350	0.023573
FOXRED2	-0.023559
DCAF15	0.023528
LTC4S	-0.023490
FAM156A	0.023426
CYFIP1	-0.023385
IGFBP4	0.023373
MPO	0.023359
LAPTM5	-0.023344
SPNS1	-0.023328
ADCY3	0.023315
ZNF267	0.023307
SLC2A3	-0.023265
RAD21	0.023227
CCDC144B	-0.023212
SCYL1	-0.023196
MZT2B	-0.023188
SLAMF7	0.023141
ASCC2	-0.023099
TIMM10	-0.023072
FEM1C	0.023063
USF1	0.023054
SLC5A3	0.023044
GPR171	0.023041
NOP56	-0.023011
LYPLA2	0.023011
DDX3X	0.022949
SMIM14	-0.022886
ZNF667	-0.022877
APOBEC3F	-0.022863
SLC38A2	0.022862
ARID3C	0.022859
ITGB7	-0.022825
EIF1AY	-0.022814
GOLGA5	0.022760
TMEM140	0.022736
YWHAE	0.022734
TMEM243	0.022697
HLA-DQA2	0.022669
GIMAP1	-0.022647
CD247	-0.022597
ATP5H	-0.022584
LTN1	0.022537
LIPA	0.022500
C7orf50	-0.022394
VPS41	-0.022366
SPTAN1	0.022338
FAM110A	-0.022281
GMNN	0.022280
OSCAR	0.022277
FAN1	-0.022268
PAQR4	-0.022261
PALLD	0.022248
STARD10	0.022215
ARL2	-0.022203
CTLA4	0.022101
UBC	0.022095
HLA-DQB1	0.022092
LRP1	0.022081
CNOT3	0.022077
GNB4	-0.022073
HLA-DPB1	0.022051
TOMM7	-0.022013
PTTG1IP	-0.022008
NUBPL	-0.021991
SLC48A1	-0.021985
CERS5	-0.021966
CRIPAK	0.021960
HSD17B14	0.021929
TXN2	-0.021885
SBNO2	0.021875
JUND	0.021836
CLN6	-0.021756
FCGR3A	0.021750
DRAM1	0.021736
DDX3Y	-0.021639
C19orf53	-0.021595
HNRNPC	-0.021581
CCDC106	-0.021557
LAS1L	-0.021535
NDUFA3	-0.021530
GHITM	0.021394
OLAH	-0.021360
PLA2G4C	0.021358
SULF2	0.021345
PRRC2A	0.021305
PID1	0.021304
POLR2A	0.021302
ADRM1	0.021215
FSIP2	0.021194
TRIM47	-0.021153
HLA-C	0.021147
ALDH9A1	-0.021146
PARVG	0.021131
GPR183	0.021130
SPARC	-0.021043
POLD2	-0.021000
MTFR1L	-0.020999
VAT1	-0.020998
TCL1A	-0.020990
DRG2	0.020966
C1D	0.020965
PDAP1	-0.020944
POMGNT1	-0.020907
DBF4	-0.020904
HSPA4	-0.020869
RPS27A	-0.020832
DDX11	-0.020825
SELO	0.020800
PDIA4	-0.020759
HMHA1	-0.020749
ZFP36	-0.020699
MORC2	-0.020694
TXNIP	-0.020670
GATAD2A	-0.020645
FTO	-0.020641
ATP1A1	-0.020581
RPS21	-0.020564
LCK	-0.020492
CDC27	0.020467
KIAA0408	-0.020458
TMEM9	-0.020437
NT5DC2	0.020422
STAT1	0.020420
EIF3H	-0.020416
CCL22	-0.020406
EPN1	0.020402
NT5C3B	-0.020398
ZNF786	-0.020393
CTSF	-0.020387
TBCA	-0.020377
EVA1B	-0.020355
S100A6	-0.020354
TIPRL	0.020315
ARFGAP3	0.020303
RPS28	-0.020272
WDR83OS	-0.020254
NDUFS7	-0.020225
SGK1	0.020223
PLXDC2	0.020213
SDAD1	0.020167
PUM1	0.020164
NAV1	0.020147
FAM53C	-0.020121
APOPT1	-0.020107
MAF	-0.020090
ZC3H3	0.020070
APOE	0.020058
DEFA1	0.020041
SRD5A3	-0.020022
PAN3	0.019983
THOC3	-0.019945
CCL5	-0.019942
CLINT1	0.019934
SLC2A8	-0.019911
LYZ	0.019907
TMBIM1	-0.019893
ZC3H11A	0.019893
C16orf58	-0.019892
SLFN5	-0.019887
GALNT14	-0.019887
GNB2	-0.019884
SCAMP2	-0.019881
SYAP1	-0.019861
C5	-0.019847
EZR	-0.019813
DMC1	-0.019805
C19orf24	-0.019790
KIF2A	0.019788
PI4K2B	0.019780
NDUFA7	-0.019762
SDSL	-0.019749
RPL29	-0.019720
TANGO2	-0.019718
TGFBI	-0.019700
PNPLA8	-0.019695
PRAF2	-0.019692
RBM38	-0.019691
KDM3B	0.019689
PIGX	-0.019663
CBR3	-0.019659
BST2	-0.019658
COLGALT1	-0.019554
SCP2	0.019553
SORL1	-0.019542
CNNM3	0.019474
ZFAND5	0.019473
WRB	0.019454
SLA	-0.019447
FAM129B	-0.019409
COPE	0.019382
CXorf38	0.019366
TGM1	-0.019352
MBNL1	0.019342
SNF8	-0.019321
CHMP2A	-0.019314
S100A11	-0.019292
PRPF31	0.019287
GATAD2B	0.019278
SDCBP	0.019276
PDE4C	-0.019272
STK40	0.019261
RPS12	-0.019256
NDUFC2	-0.019243
RCAN3	-0.019240
LTB4R	-0.019224
FAM200A	-0.019220
MIIP	-0.019201
ADRA2B	-0.019197
FURIN	0.019192
CARD16	-0.019175
SHARPIN	-0.019101
PAGR1	0.019088
ZNF428	-0.019088
TSPAN31	-0.019073
TCEAL4	-0.019068
DIRAS1	0.019057
METTL2B	-0.019051
IMP4	-0.019025
LLPH	-0.019012
AGFG1	0.018995
CST3	0.018969
TAF10	-0.018952
ISYNA1	-0.018947
XPO1	0.018946
LY96	-0.018908
KIDINS220	0.018899
PHACTR1	0.018889
NAPRT	-0.018878
GTF3C1	0.018873
SGSM2	0.018868
VGLL4	0.018865
SLC39A1	-0.018860
KLRB1	0.018853
LASP1	-0.018849
SRPX	0.018827
OAZ2	-0.018820
CDC34	0.018815
CRACR2A	0.018804
HSPA6	0.018793
CNNM2	-0.018776
CACNA1B	0.018771
GDI1	0.018763
DTD2	-0.018754
PRG2	0.018745
LRRC59	0.018722
RPLP2	-0.018720
WNT11	-0.018705
ZNF669	-0.018695
ZNF440	-0.018658
KRT24	0.018653
ATP13A2	0.018652
FCGR2A	-0.018647
RGS10	-0.018645
ENPP2	-0.018637
PCNT	0.018617
CALR	-0.018582
TNIP3	-0.018557
CMTM6	0.018509
PRDX4	-0.018490
RPS25	-0.018469
LPXN	0.018467
RPL36AL	-0.018435
ACTN1	-0.018427
DPH5	-0.018412
DOHH	-0.018391
RFX5	0.018372
USP16	0.018338
NUBP2	-0.018302
G6PD	0.018300
ALG3	-0.018268
MT1X	-0.018263
JDP2	-0.018248
ZNF22	0.018235
TCEAL3	-0.018233
GBP1	0.018223
RPL36A	-0.018208
TMUB1	0.018200
VMP1	0.018197
MTMR14	0.018193
PFKL	-0.018190
YPEL3	0.018187
MYO1G	0.018177
IL4R	-0.018171
SLC39A10	0.018162
TRAPPC8	0.018159
COMMD8	0.018111
RNF125	-0.018101
PSMC3	-0.018100
TRIM50	-0.018086
RAB35	-0.018068
CBWD2	0.018059
SERF1A	-0.018056
ALG6	0.018043
ZBTB3	-0.018040
GRAP2	-0.018035
TBC1D32	-0.018025
LRMP	0.018025
LDHA	0.018024
RHEB	0.018024
KLHL22	-0.018015
DNAJC7	-0.018002
GPI	-0.017965
RHOXF1	0.017962
MAP3K8	0.017932
GFM1	0.017923
OR8B12	-0.017922
GADD45B	0.017919
TSPYL2	-0.017906
SLC36A4	0.017903
EEF2K	-0.017898
RAB9A	0.017894
PTPN23	0.017884
PBLD	-0.017882
REPS1	0.017874
PARP1	-0.017867