!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!ligand_name	interleukin-1
!ligand_id	3553
!cell_type	chondrocyte
!organism	rat
!end_metadata
MMP3	0.202712
CCL13	0.194992
CCL20	0.183719
MMP13	0.178910
CXCL2	0.174446
PTGES	0.151079
SLC20A1	0.148775
LCN2	0.145340
PTGS2	0.128994
AKR1B10	0.128268
PLAT	0.125850
ASS1	0.114966
IER3	0.098138
MMD	0.093086
WISP2	-0.092173
FABP5	0.090143
COL3A1	-0.089515
IL6	0.088886
SOD2	0.086288
THBS2	-0.086174
GJA1	-0.080040
OGN	-0.079434
LBP	0.078575
CX3CL1	0.073492
TLR2	0.071674
GREM1	0.071575
P4HA1	-0.068231
GADD45A	0.067107
PRDX5	0.066884
CXCL16	0.066730
CD44	0.066466
COL1A2	-0.066095
VIM	-0.064647
CEMIP	-0.064164
H19	-0.063616
ANXA1	-0.062754
ACTB	-0.062289
ESM1	0.061208
COL9A1	-0.061075
RAB32	0.061058
CTGF	-0.060859
FAM198B	-0.059290
PRKCDBP	-0.058846
MMP12	0.058338
MXRA8	-0.057198
NOV	0.057014
SDC4	0.055322
TNIP1	0.055238
HMOX1	0.054817
SDC2	-0.054650
FST	0.054575
UGDH	0.054562
COL1A1	-0.054387
GFPT2	0.054324
ITGA11	-0.054228
SLC29A1	0.054000
AMPD3	0.053008
ZC3H12A	0.052878
COL2A1	-0.052844
FURIN	0.052507
CCDC80	-0.051489
PRNP	-0.051276
NDUFA4L2	-0.051036
COL8A2	-0.050680
ASPN	-0.050514
S100A6	-0.050469
COL5A2	-0.050180
FHL1	-0.049158
NFKBIA	0.048981
LGALS1	-0.048675
S100A10	-0.048622
SCRG1	-0.048520
HSD11B1	0.047964
TGIF1	0.047856
CA9	-0.047793
TFPI2	0.047678
ICAM1	0.047442
NFKBIZ	0.047249
TGM2	0.047035
PLS3	-0.047013
SEC61B	-0.046835
TIMP1	0.046805
SEPT7	-0.046803
NQO1	0.046374
COL11A1	-0.045047
S100B	-0.044693
LAPTM4A	-0.044353
EGLN3	0.044182
CPD	0.044174
BTG1	0.043888
OMD	-0.043886
FSTL1	-0.043810
GPNMB	0.043459
EMP1	-0.043417
IRAK3	0.043183
TMED10	-0.043062
GYPC	0.043028
KDELR2	-0.043015
TAGLN	-0.042530
PRSS23	-0.042314
SERPINH1	-0.042235
PLAU	0.041981
FAM129B	0.041968
VDAC3	0.041964
PDPN	0.041936
FABP4	0.041891
TNN	-0.041603
SPARC	-0.041554
RIPK2	0.041117
CDC42EP3	-0.040891
LHFP	-0.040740
SLC25A37	0.040473
NTN1	0.040006
DPYSL2	-0.039952
PRPS2	-0.039918
STAMBPL1	0.039605
SLPI	0.039549
RND3	-0.039479
LXN	-0.038578
TXNRD1	0.038422
GAPDH	-0.038328
ITM2B	-0.038021
DSTN	-0.037782
GSTP1	0.037601
OSTC	-0.037515
PPP3CA	0.037466
FAT1	-0.037445
TGFB2	-0.037130
LIMS1	-0.036847
INSIG1	0.036819
PFN1	-0.036680
RECK	-0.036658
ITGBL1	-0.036223
BSG	-0.036180
CCND1	0.036102
CAV1	-0.035916
RNASE4	-0.035627
RBPJ	0.035623
UAP1	0.035587
ZFP36L1	0.034540
GNG12	0.034284
C1QTNF3	-0.033994
ACKR3	0.033860
COX1	-0.033651
NINJ1	0.033512
ATP11A	0.033323
TNFRSF12A	0.032956
CDO1	0.032809
PCOLCE	-0.032730
AXL	0.032564
SCARA5	-0.032321
PDGFRL	-0.032226
LDHA	-0.032225
TPI1	-0.032109
LOXL3	-0.032086
MORF4L2	-0.032063
GAS6	-0.032030
TUBB2A	-0.031845
MAGED1	-0.031820
CIB1	0.031589
SERINC1	-0.031507
SLC2A1	0.031484
PMP22	-0.031332
COL4A1	0.031265
PPIC	-0.030964
SAP18	0.030901
ADAM17	0.030853
C3	0.030812
SEPP1	-0.030745
IL6ST	0.030712
VKORC1	-0.030576
ANGPTL4	0.030572
NEDD9	-0.030389
SPATS2L	-0.030379
BTG2	0.030359
TMEM43	-0.030296
RPL6	-0.030230
EHD2	-0.030177
ERCC1	0.030128
ATP6V1G1	0.029975
FMOD	-0.029925
SLC25A5	0.029911
SLC11A2	0.029842
SCIN	0.029761
UPP1	0.029711
NPR3	-0.029526
GDF15	0.029446
DAB2	-0.029248
THBS4	-0.029045
BHLHE40	0.028964
GDE1	0.028789
PDGFRA	0.028707
CSF1	0.028664
RPL13A	-0.028434
HAPLN1	-0.028402
KDELR3	-0.028245
RPL10	-0.028038
GDA	-0.027970
TMEM59	-0.027722
MAPK6	0.027711
COMP	-0.027682
SMOC1	-0.027607
DKK3	-0.027539
RPS16	-0.027525
SERPINE2	0.027523
KLF15	0.027522
ZNRF1	0.027471
RPLP0	-0.027377
HOXA11	-0.027374
ACADL	0.027341
RPS6	-0.026982
PQLC3	-0.026975
RPS19	-0.026921
GOLIM4	-0.026917
NUCB1	0.026759
RIOK3	0.026698
HSPH1	0.026585
RPS2	-0.026573
ND3	-0.026419
PALMD	-0.026361
TXNIP	-0.026251
AP2M1	-0.026238
AHNAK	-0.026172
ALDH1L2	-0.026097
SLC7A8	0.026071
CYP7B1	0.025930
PSMA6	0.025845
NEK6	0.025824
DCN	0.025799
ADM	0.025737
EPAS1	0.025694
VEGFA	0.025672
SERINC3	-0.025643
AQP1	-0.025640
PRELP	-0.025490
SEPT11	-0.025418
CEBPB	0.025381
F2R	-0.025376
CDH11	-0.025350
GSAP	0.025347
EDF1	0.025188
CD200	-0.025183
PGK1	-0.025062
WBP5	-0.025053
SETD8	0.025052
GSTA5	0.025017
KCNK2	-0.024973
FAM180A	-0.024935
RPL11	-0.024880
ACTA2	-0.024733
ARMCX2	-0.024728
OAZ1	-0.024642
FBXL5	0.024486
PIEZO1	0.024430
CSGALNACT1	-0.024405
PGAM1	-0.024315
EID1	-0.024248
FN1	-0.024162
DYNLL1	-0.024154
F3	0.024121
SKIL	0.024100
SLC39A8	0.024100
FAU	-0.024067
ND1	-0.024053
LOXL1	-0.024018
SEC24D	-0.023995
CYP1B1	0.023896
CD47	0.023895
IDS	-0.023894
SPTAN1	-0.023817
PLXDC2	-0.023788
BGN	-0.023764
PTP4A1	0.023702
TGFB3	-0.023654
RARRES2	-0.023600
LMCD1	-0.023490
KPNA3	0.023367
RPN1	-0.023342
SEC23A	-0.023310
CALU	-0.023234
ATP6V1E1	0.023194
ANXA3	-0.023133
FOSL1	0.023117
PLSCR1	0.022988
HSPB1	-0.022970
TSPAN3	-0.022874
RPS17	-0.022862
CDKN3	-0.022841
SRP14	-0.022820
PRDX6	0.022719
RPL9	-0.022688
FTL	-0.022676
ARF4	-0.022670
SERPINE1	0.022654
COPZ2	-0.022570
LITAF	0.022432
FAM114A1	-0.022398
FIGF	-0.022382
RPS11	-0.022372
ATP5L	-0.022354
CLEC11A	-0.022316
PNRC1	0.022276
CLMP	0.022271
SAR1A	-0.022228
TMED9	-0.022218
HNRNPK	-0.022043
PLA2G4A	0.022019
PROCR	0.021969
COL14A1	-0.021866
DBI	-0.021833
PMEPA1	0.021825
EMP2	0.021694
OPTN	0.021637
CLIC4	-0.021621
ID3	-0.021558
RPS12	-0.021329
ATF4	0.021299
XPO1	0.021268
SLC39A14	0.021224
KDELR1	-0.021101
NT5DC2	-0.021059
RCN3	-0.021030
GPX1	-0.020987
COL4A2	0.020960
TSPAN6	-0.020949
NFKB1	0.020911
GPX7	-0.020835
MDM2	0.020820
SEPT2	-0.020818
HNRNPA0	-0.020807
PRDX1	-0.020794
RPS8	-0.020772
TGFB1	0.020756
SAT1	0.020716
RPS29	-0.020678
VCL	-0.020484
TIMP2	-0.020464
MAP3K8	0.020365
GRB10	-0.020361
PLOD2	-0.020344
KCMF1	0.020295
ERRFI1	0.020288
COL5A1	-0.020281
FGF9	0.020265
SERF2	-0.020220
ATP6V1F	0.020187
SQSTM1	0.020071
BNIP3	-0.020068
PKIG	-0.020018
H2AFZ	-0.019992
CYTB	-0.019931
TMED2	-0.019859
SGK1	0.019849
ATP6V1C1	0.019797
SOD3	-0.019776
RPS14	-0.019737
DDX5	-0.019638
MAFF	0.019638
ARHGDIB	0.019633
KLHL13	-0.019586
CDKN1B	-0.019574
EAF1	0.019569
PELI1	0.019563
MSN	0.019437
ARL1	-0.019393
SPCS1	-0.019213
BMP4	-0.019207
RPL23	-0.019176
CAT	0.019140
PPIA	-0.019114
TFG	0.019096
SLC4A4	-0.019080
ANAPC5	-0.019068
MRFAP1	-0.019040
MAP6	0.019015
GLRX3	0.018914
CTHRC1	-0.018908
IDH2	-0.018875
ATP6AP1	-0.018818
IFITM2	-0.018806
FIBIN	-0.018781
GM2A	-0.018713
DMPK	-0.018711
VAPA	0.018691
DUSP6	0.018683
COX2	-0.018675
ODC1	0.018665
SGCE	-0.018659
GNB2L1	-0.018604
RHOA	-0.018568
NFKB2	0.018554
TMEM9B	-0.018535
SLC48A1	0.018444
ACPL2	-0.018442
ADAMTS5	0.018441
REEP5	-0.018411
THBD	0.018320
MORF4L1	-0.018293
TMEM261	-0.018265
TIFA	0.018232
MYADM	-0.018183
MAPKAPK2	0.018182
CPE	-0.018129
RTN4	-0.018103
CSTB	0.018098
NEURL3	0.018094
RPS26	-0.018063
RNF149	0.018025
FADS1	-0.018012
FZD2	-0.017974
MTAP	0.017974
SEC22B	-0.017950
ITPR3	0.017947
GNG10	-0.017923
SULF1	0.017899
AGA	-0.017841
NDRG1	0.017825
LMAN1	-0.017781
UBC	-0.017768
S100A4	-0.017719
CTDSP2	-0.017648
ANGPT1	0.017638
PVR	0.017632
ALDH18A1	-0.017627
XDH	-0.017606
GCNT2	0.017603
ZMIZ1	0.017597
TSLP	0.017587
DUSP5	0.017544
PAPSS1	-0.017535
LOX	-0.017457
SF3B5	-0.017417
RPL3	-0.017411
ARPC3	0.017403
PCP4	0.017395
CD81	-0.017366
PPP1R15A	0.017356
PNRC2	-0.017306
ID1	-0.017306
COMMD3	-0.017302
TUBB	-0.017205
RPL19	-0.017180
SCARA3	-0.017137
CNKSR3	-0.017128
CCL5	0.017127
MYL12B	-0.017110
ZC2HC1A	-0.017091
FTH1	0.017053
PSMD10	0.017024
MITF	0.016970
LHFPL2	0.016944
CTSV	-0.016917
SFT2D1	0.016901
CLU	-0.016882
SSR1	-0.016815
IGFBP7	0.016768
PGRMC2	-0.016757
CYP26B1	0.016754
TM2D2	-0.016732
RPL4	-0.016674
FKBP7	-0.016671
CRYAB	-0.016623
CDK14	-0.016615
PXN	0.016606
CST3	-0.016563
ACSL4	0.016540
ANXA5	-0.016539
GNAS	-0.016505
NPAS2	0.016503
B2M	0.016473
PDGFRB	-0.016446
COLEC12	-0.016442
HMGN1	-0.016434
ITGA3	0.016429
EIF5	0.016425
MTMR7	0.016385
STEAP1	0.016383
RASGRP3	-0.016374
SEC13	-0.016368
RPL21	-0.016347
SLC38A2	-0.016339
CMPK1	-0.016308
MMADHC	-0.016300
CNN3	-0.016267
MMP2	0.016266
YBX1	-0.016244
PSME1	0.016228
TNFRSF11B	0.016223
SDCBP	0.016201
ENO3	-0.016099
LIMA1	-0.016059
COPA	-0.016036
RYK	-0.015975
ADAMTS1	0.015944
PTK7	-0.015943
UCK2	0.015893
KANSL2	0.015865
LPPR5	-0.015844
ITGB1	-0.015801
EXT2	-0.015783