!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	angiotensin II
!smiles	CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N
!pubchem_cid	172198
!cell_type	Heart (PKCζ - Knockout)
!organism	mouse
!end_metadata
GDPD3	-0.168739
POSTN	0.110698
MFAP5	0.100955
CILP	0.099900
COL3A1	0.096008
COL5A2	0.084224
LTBP2	0.074065
COL1A1	0.070322
IGFBP6	0.065136
ALAS2	-0.061909
SPP1	0.058542
CD74	0.056122
COL1A2	0.052757
HLA-DQA1	0.051453
HLA-DRB5	0.051447
PHLDA1	0.051189
PDGFRL	0.049506
RBMXL2	-0.047815
CTHRC1	0.047696
ISLR	0.047171
RBP1	0.047070
PLA2G5	-0.046711
ANO10	-0.046516
MGP	0.046474
SFRP2	0.046368
FIBIN	0.046000
FSTL1	0.045928
NPPA	0.045769
COMP	0.044665
HLA-DQB1	0.044499
LECT1	-0.044057
EFEMP1	-0.044026
MPEG1	0.043965
CFH	0.043921
COL4A1	0.043853
MMP2	0.043712
TXNIP	-0.043604
PPP1R3C	0.043289
MYLK4	-0.043226
TMEM45A	0.041877
ASPN	0.041871
TIMP1	0.041688
TBC1D10C	-0.041562
RNASE2	0.041348
ITGBL1	0.040377
MFAP4	0.040354
FAM214A	-0.039828
HCN1	0.039483
CCDC80	0.039454
COL8A1	0.039157
DDIT4	0.038927
EDN3	0.038525
COL6A1	0.037207
AHRR	-0.037081
CRLF1	0.036812
COL4A2	0.036079
ADAMTS1	0.035951
COL6A2	0.035686
UCP3	-0.035449
BGN	0.034998
TMEM14A	-0.034953
BHLHB9	-0.034834
SOCS3	-0.034831
SERPINF1	0.034617
CA4	0.034563
OAF	0.033798
LOX	0.033469
KLF2	0.033289
FAM46C	-0.033066
LY86	0.033029
KLF15	-0.032956
P4HA1	0.032904
FBXO32	-0.032841
VWF	0.032553
UBE2L6	-0.032153
C1QA	0.032058
CITED2	-0.031593
TUBB2A	0.031516
CASQ1	-0.031478
TNFRSF12A	0.031331
PENK	-0.031279
PFKFB1	-0.031201
SPARC	0.030843
C1QB	0.030159
COL6A3	0.030050
FAM198B	0.029960
BPGM	-0.029884
FKBP5	0.029839
ACTA1	0.029764
GPX3	0.029677
COL15A1	0.029515
JUN	0.029294
CES1	-0.029145
GATA4	0.029119
PAMR1	0.029104
COL14A1	0.029052
PDK4	-0.029004
LOXL1	0.028949
INSIG1	-0.028941
COL5A1	0.028910
PDCD4	-0.028831
UPP1	0.028756
C1QC	0.028683
EGR1	-0.028664
SNCA	-0.028601
IGF1	0.028564
MYH7B	-0.028457
SERPINH1	0.028439
PQLC3	0.028436
WISP2	0.028333
HTRA4	0.028319
NFU1	-0.028260
TYROBP	0.028123
EPHB1	-0.028032
PPWD1	-0.027880
ANKRD23	0.027832
SYNPO2L	0.027631
PHKG1	-0.027606
AZIN1	0.027581
ARRDC3	-0.027294
JUNB	-0.027279
THBS1	0.027157
PFKP	0.027151
CLK1	-0.027134
BCL6	-0.027124
ANKRD1	0.027108
QPCT	0.027080
PRMT1	-0.027055
FNIP1	-0.026964
AGMO	0.026744
PCOLCE2	0.026729
ERRFI1	0.026669
PFKFB4	0.026668
DENND4C	-0.026636
CHAC1	-0.026633
LGALS3	0.026604
CDKN1A	0.026484
PI16	0.026478
KCNH7	-0.026448
CLIC5	0.026431
PLA2G7	0.026418
RWDD2A	-0.026377
CISH	0.026336
AHNAK2	0.026306
TGFB2	0.026261
KLF10	-0.026023
PLVAP	0.025714
HIC1	0.025551
HLF	-0.025453
CTSK	0.025324
PIRT	0.025285
CLEC6A	0.025269
C8G	-0.025258
ABLIM3	-0.025219
FAH	0.025217
IRX1	-0.025201
CIRBP	-0.025142
MSN	0.025134
C20orf196	-0.025045
CUTC	-0.024980
FETUB	0.024849
HIST1H3G	0.024831
MYH6	0.024826
APOE	0.024819
SLC25A23	0.024675
EMR1	0.024674
PDE7A	-0.024570
BMPER	0.024567
SERPING1	0.024538
CLU	0.024537
PCDHB16	0.024489
PPM1H	-0.024481
DKK3	0.024475
C14orf37	-0.024361
PHF21B	-0.024341
DECR1	-0.024317
EFHD2	0.024292
TMEM176B	0.024282
BCL2L11	-0.024211
RRAD	-0.024205
SGK1	0.024177
L2HGDH	-0.024067
ADAMTS2	0.023957
SGOL2	-0.023948
PTN	0.023930
FBN1	0.023908
EML2	-0.023903
BCDIN3D	-0.023866
TMEM184B	0.023839
CRIP1	0.023839
PLEKHO1	0.023821
MSH6	-0.023744
CASP8AP2	-0.023738
CLEC3B	0.023684
PCOLCE	0.023637
PNCK	-0.023578
LONRF1	-0.023566
CXCL14	0.023469
FRZB	0.023443
CREBBP	-0.023415
KLF11	-0.023397
HSPB7	0.023378
CLEC10A	0.023369
GCK	0.023323
ADAM8	0.023286
SLC22A3	-0.023285
SGPP2	0.023250
UPF3B	-0.023217
TMEM35	0.023170
PODXL2	-0.023169
PIM3	-0.023167
PNMA5	0.023105
S100A6	0.023086
C2orf40	0.023044
ECM1	0.023034
CNKSR1	0.023032
METTL14	-0.023010
SYDE2	-0.022990
MSRB3	0.022876
TMEM176A	0.022858
ALKBH2	0.022852
HEG1	-0.022819
RAB5C	-0.022814
VCL	0.022788
SH3BGRL3	0.022751
S100A4	0.022715
GAS1	0.022698
TIMP3	0.022665
FGL2	0.022654
TGFB3	0.022635
KLF4	0.022617
CRY2	-0.022601
TSHZ3	0.022598
CSF2	-0.022569
HLA-DMA	0.022528
TP53I11	0.022507
CENPF	-0.022506
VIM	0.022462
DSP	0.022418
TSPO	0.022403
FTL	0.022403
PHLPP1	-0.022353
MYOT	0.022352
ZNF454	0.022298
FXYD5	0.022269
IRF5	0.022176
FNIP2	-0.022163
RIT1	-0.022115
TMEM119	0.022097
UBE3D	-0.022079
DNAJB1	0.022035
MPPED2	-0.022031
HSD17B8	-0.022022
CCNB1IP1	0.021910
PGAM1	0.021871
SASH3	0.021818
CD180	0.021817
MYH7	0.021816
LDOC1L	-0.021789
VEGFA	0.021743
GRAMD4	-0.021703
NR4A1	0.021637
IGFBP4	0.021585
ETV5	0.021563
EMILIN2	-0.021515
SH2D4A	0.021482
TGFB1I1	0.021421
FCER1G	0.021418
FAP	0.021357
IFIT1B	0.021306
LUM	0.021179
PRSS23	0.021118
UTS2	0.021091
EGR3	0.021020
FXYD6	0.020992
NAGLU	-0.020975
AKAP12	-0.020896
CORO6	0.020860
YDJC	0.020856
HSPA2	-0.020804
TSSC4	0.020785
KLHL2	-0.020783
FBLN1	0.020775
MXRA8	0.020749
GXYLT2	0.020743
EVI5	-0.020732
HPX	0.020715
HSP90B1	0.020704
MBIP	-0.020650
C9orf135	0.020627
EPHA4	-0.020627
HSPB1	0.020609
RNASE4	0.020607
KDELR3	0.020581
C10orf107	-0.020580
SPSB4	0.020577
ADAMTSL3	0.020574
MS4A7	0.020571
SERAC1	-0.020537
C9orf173	0.020532
NRROS	0.020525
LYZ	0.020512
DYNLL1	0.020503
ZBTB18	-0.020462
TGM2	0.020427
AXL	0.020412
HSBP1L1	-0.020385
SLC17A7	-0.020379
PPIC	0.020358
TMPRSS13	-0.020357
CYB561	0.020294
GORASP2	0.020270
PDLIM5	0.020233
LRRC16A	0.020184
PM20D2	-0.020173
SERP1	0.020132
UNK	-0.020126
MEDAG	0.020116
DUSP6	-0.020087
SIRT1	-0.020066
CEP104	-0.020063
SLC12A9	0.020044
MRPL39	-0.019967
ADCK5	-0.019960
LRRC45	-0.019928
CAP1	0.019923
CYBB	0.019912
FAM26D	0.019899
WNK1	-0.019881
CNN2	0.019857
KCNV2	-0.019844
CLEC4C	0.019823
PER1	-0.019799
ADTRP	0.019798
SERTAD4	0.019794
STK11IP	-0.019732
KBTBD7	-0.019727
ALDH1B1	-0.019711
S100A8	-0.019706
LEPREL4	-0.019653
PACRGL	-0.019644
FIG4	-0.019617
PRDM15	-0.019612
GPT2	-0.019532
C11orf52	0.019450
DNAJB14	-0.019437
SVEP1	0.019409
NUDT1	-0.019384
SPARCL1	0.019361
THBS4	0.019317
PPAT	-0.019294
PRNP	0.019290
SRA1	0.019287
MRGPRF	0.019269
C1R	0.019263
AGAP3	0.019252
RASGEF1B	-0.019205
DGKI	-0.019184
OLIG1	0.019171
SERPINE2	0.019164
NID2	0.019162
IFLTD1	0.019106
CD38	0.019102
DFNA5	0.019099
RASL10A	0.019086
DUSP27	0.019016
MANF	0.019014
EMP3	0.018965
S1PR1	0.018962
SLC36A2	-0.018944
PPM1E	0.018941
ANKRD16	-0.018920
CLEC7A	0.018911
GLS2	-0.018901
C8orf58	0.018888
GSG1L	-0.018877
PHKA1	-0.018872
NSMCE1	-0.018845
GDF10	0.018836
CCDC110	0.018804
CATSPER3	0.018769
IRX3	-0.018764
CTAGE5	-0.018724
ANGPTL4	-0.018721
IER5	0.018714
TANC1	-0.018702
FKBP1B	0.018701
STEAP4	0.018678
UTP20	-0.018650
PDP1	-0.018650
MPST	-0.018630
RTN2	-0.018629
TMEM88	0.018626
LGALS9B	0.018610
NAT1	0.018604
BEND4	0.018592
THRAP3	-0.018585
CACNB3	0.018578
SLC13A4	0.018578
PNOC	0.018563
CPXM2	0.018543
UBE2G2	0.018535
GEM	0.018524
GCA	-0.018520
ZNF385A	-0.018499
SLC25A33	-0.018486
ZNF585A	0.018483
TUBA8	0.018478
ALG8	0.018465
CARHSP1	0.018444
LMAN1L	0.018409
GOLM1	0.018405
TMTC4	-0.018389
C14orf159	-0.018384
CLCNKA	0.018377
SFT2D3	-0.018371
PLA1A	0.018366
SLC45A3	0.018354
KLHDC1	-0.018346
CREB3L1	0.018332
MSL2	-0.018329
MAGEA11	0.018325
IL2	0.018323
ZADH2	-0.018302
SRMS	0.018297
RASL11B	0.018286
FAM19A5	-0.018274
PEX12	-0.018265
VWC2	-0.018263
SLC16A13	-0.018234
TTC9	0.018231
WWTR1	0.018231
DHRS11	-0.018226
KLC3	-0.018220
ZYX	0.018197
SUSD1	0.018185
COL8A2	0.018184
DPEP1	0.018173
PAPOLG	-0.018171
SLC39A4	-0.018161
ATG10	-0.018148
SKAP1	0.018147
OASL	0.018142
HAND2	0.018138
C1S	0.018129
GUCY1B3	0.018128
GPATCH1	-0.018126
RAPSN	-0.018125
PLA2G15	0.018120
TNXB	-0.018084
CHD2	-0.018054
CAMP	0.018009
ITGA10	0.017989
CNGA4	0.017985
HSPA1L	0.017978
ANGPTL3	-0.017972
PTPN22	0.017971
GPX1	0.017936
VPREB1	0.017933
C11orf86	0.017932
LAMB3	-0.017916
HSH2D	0.017878
NINJ1	0.017863
VASP	0.017861
ZNF667	-0.017846
JPH2	0.017823
SULT1C3	-0.017809
HSPB3	0.017809
PPP1R18	0.017808
CCIN	0.017803
PRELP	0.017760
CDH11	0.017754
SEC14L5	-0.017738
AASDH	-0.017731
ESPN	-0.017731
TIMP2	0.017681
NEFH	-0.017669
FABP5	0.017667
IGFBP7	0.017659
AIFM1	-0.017655
TBCE	-0.017646
CCDC159	-0.017632
MEST	0.017603
CEP72	-0.017596
ISG20	-0.017593
ADAMDEC1	0.017589
FRMD5	0.017587
TSPAN5	0.017586
NUPR1	0.017570
LXN	0.017549
PRDM5	-0.017545
SNTA1	0.017536
CNKSR3	-0.017530
SLC26A5	-0.017523
USP54	-0.017509
AKR1B10	0.017496
WIPF3	0.017468
TMEM245	-0.017468
TWSG1	0.017467
ACTR1B	-0.017457