!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!cell_type	Breast
!drug_id	CID 5757
!drug_name	Estrogen
!organism	Human
!end_metadata
BMPR1B	-0.121688
SULF1	0.101879
AGTR1	-0.095725
AARD	-0.092316
TPRG1	-0.083591
NRIP3	-0.081580
KCNJ3	-0.079602
ZNF804B	0.079270
SCUBE2	-0.078196
LIN7A	-0.076034
KRT40	-0.072008
LRRN1	-0.070625
C6orf141	0.070305
FAM19A2	0.069479
LRRN3	0.068356
KRT23	-0.066034
LURAP1L	-0.064181
DEGS1	-0.062649
SLCO2A1	0.062104
CA2	0.062018
ARHGAP36	-0.060151
APOD	-0.059571
AMIGO2	-0.059201
FGF10	-0.058126
SERPINA3	-0.058125
PGR	0.057515
GRIK3	0.056540
AGR3	0.056402
MGAT4A	-0.056258
SOX5	-0.056102
STXBP5L	-0.055533
MMP16	-0.053266
CYP4Z2P	-0.052883
MAML3	0.052777
PIEZO2	-0.052451
FBXL13	0.051631
CCDC85A	0.051425
HGD	-0.050926
ZBTB18	0.050776
ANXA1	0.050745
PLEKHH2	-0.050557
CDC20B	0.049315
ALDH3B2	-0.048945
CMYA5	-0.048521
VCAN	0.047958
KIAA1324L	-0.047801
IGSF1	-0.047724
CRISP2	0.047635
MCOLN3	-0.047565
SYTL2	-0.047273
CLSTN2	-0.047129
CHI3L1	0.047020
KCND2	-0.046299
SERPINI1	-0.046222
FOXJ1	0.046061
TAT	-0.045854
HIST1H2BM	-0.045431
SIPA1L2	-0.045205
TGFB2	0.045039
NECAB1	-0.044839
MGLL	-0.044669
CRISP1	0.044629
KAL1	-0.044548
WLS	0.044439
EDN1	0.044038
ADRA2A	0.043758
NFE4	0.043730
MLLT4	-0.043444
UGCG	-0.043166
ASCL1	-0.043131
LONRF2	-0.042116
CCDC175	-0.041911
NELL2	-0.041547
ROBO2	0.041047
AKT3	0.041001
CABLES1	0.040906
IFI27	-0.040854
ZAK	-0.040264
CXCL12	0.039986
LYPD6B	-0.039981
ITGA6	0.039879
CTTNBP2	-0.039842
PREX1	0.039436
RGS22	-0.039222
B4GALT1	0.038837
CYP4F22	-0.038610
IFIT1	-0.038586
CADM2	0.038431
PITX1	0.038158
SDK2	0.037981
CCL28	-0.037887
TNIK	-0.037430
DCLK1	-0.037310
MUC5B	0.037072
NR4A2	-0.037063
KIF5C	-0.036975
BMP4	0.036921
SNORA36A	-0.036752
XYLT1	0.036620
SCNN1G	0.036602
CEACAM6	0.036053
ACSS3	-0.035685
MSX2	0.035618
TMEM45A	-0.035615
FAM184B	0.035484
TFPI2	-0.035304
SLC30A8	-0.035118
GOLM1	0.035037
ANTXR2	-0.034918
IFI44	-0.034772
GPR160	-0.034767
MIPEP	0.034736
OAS1	-0.034684
DIO1	0.034670
DACH1	-0.034269
LRP2	-0.034250
PM20D2	-0.034163
MAMLD1	0.034093
TRIM55	-0.034089
TM4SF1	-0.034039
LSM8	-0.033870
KCNH1	0.033649
CTSH	-0.033468
ZNF704	-0.033259
PDGFD	-0.033238
LINC00238	-0.033226
TSPAN5	-0.033130
SECTM1	-0.033128
FAM196A	-0.032269
THRSP	-0.032232
PIP	-0.032089
CLIP4	-0.032079
ERO1LB	0.032046
ARHGAP29	-0.031897
MYO3B	-0.031841
RAPGEFL1	0.031767
CRISP3	0.031758
IL20RA	-0.031596
CCRN4L	-0.031498
PXK	0.031479
PCDHB2	0.031308
ABI3BP	-0.031166
SLCO3A1	-0.030950
TSKU	0.030915
ABCC5	-0.030865
RCAN3	0.030846
KCNS3	-0.030728
PCED1B	-0.030702
CCDC88C	0.030686
IFIT5	-0.030684
AGR2	0.030626
GSTM1	-0.030334
BAMBI	0.030275
KIAA0922	0.029923
FAM65C	-0.029881
RBBP8	0.029768
KCNJ2	0.029689
LFNG	0.029559
PLXDC2	-0.029552
TMEM74B	-0.029527
TFF1	-0.029525
SHISA9	-0.029508
BCL11A	0.029273
RIMS4	0.029239
PTGR1	-0.029203
HMGCLL1	0.029162
PRDM1	0.029088
XKR9	-0.028876
FAM198B	-0.028822
COLEC12	-0.028702
FAM102B	-0.028632
KCNE4	-0.028569
MSN	0.028529
FARP1	0.028469
GAD1	-0.028417
PPP1R3C	-0.028361
PPFIA4	0.028277
FREM2	0.028261
KIAA1244	-0.028246
DBN1	0.028175
C1orf21	0.028139
DYRK3	0.028115
SFMBT2	-0.028077
AFF3	0.028035
SLC6A15	0.028032
LTBP1	0.028020
ZMAT4	0.027953
FGFR2	-0.027913
TMEM229B	0.027778
VTCN1	-0.027761
IPO5	0.027745
CGA	-0.027633
KIAA1467	-0.027538
DSP	0.027533
ARHGAP32	-0.027513
MAGI2	-0.027483
SPTSSB	0.027464
OAS2	-0.027323
SLC40A1	-0.027287
RARRES3	-0.027170
LYST	-0.027089
RIMS1	-0.027061
CTSC	0.027001
TTLL12	0.026990
CSMD3	0.026915
ABCA3	0.026833
BDNF	-0.026828
DPP4	-0.026779
ABCD3	-0.026767
ITPK1	0.026717
FN1	-0.026690
SUSD4	-0.026670
PDE8B	0.026667
TBC1D4	0.026577
PLCB1	-0.026416
PPP1R2	-0.026402
EVL	0.026318
FAM171B	-0.026302
NEK10	-0.026230
CDON	0.026187
REEP5	-0.026141
RTN1	-0.026102
RGS2	0.026070
KITLG	0.025969
ANKRD34B	-0.025901
DST	-0.025856
KDM7A	0.025781
SYTL5	0.025767
SLITRK6	0.025717
SLC39A6	-0.025661
CLYBL	0.025510
SYNM	-0.025505
YBX3	0.025458
MIR301A	-0.025454
CYP2B6	0.025450
IL20	0.025407
S100A14	0.025302
CACNA1D	-0.025298
PHF14	-0.025258
STC2	0.025233
OSR2	-0.025198
MPP1	-0.025191
MAP3K5	-0.025179
MCC	-0.025171
SESN3	-0.025164
ARHGEF6	-0.025142
ABCC3	-0.025129
RNF157	-0.025117
NCMAP	0.025093
DPY19L2P4	0.025040
PCDH19	0.025031
MYC	0.025030
PCDH7	0.025021
DGKD	-0.025017
TPPP3	0.025011
SNORD77	0.024985
SIX1	-0.024975
UGT8	0.024921
PAPD5	-0.024910
MID1	0.024797
PBX3	-0.024770
TSHZ1	-0.024760
SEPP1	-0.024735
EFEMP1	-0.024714
ARL15	-0.024690
SLC6A6	0.024599
LRIG1	0.024491
NVL	-0.024443
STOM	-0.024413
RNF125	0.024405
TIMP4	-0.024389
MLLT4-AS1	-0.024360
PRKG1	0.024322
ADM	0.024294
SLC7A2	-0.024252
CLU	-0.024199
RBM11	-0.024167
CBLN2	-0.024052
PABPC4	0.024031
SLC31A2	-0.023976
CPEB2	-0.023974
GPD2	-0.023962
KRT15	-0.023934
FAM129A	-0.023861
PDIA5	0.023832
C5AR2	0.023806
MAP2	-0.023770
TNS4	0.023742
ATP1B1	-0.023654
SLC7A8	-0.023638
TBC1D9	-0.023635
SULF2	0.023502
CBX4	0.023485
ATRNL1	-0.023425
GREB1	0.023391
CAB39L	-0.023378
MAP3K13	-0.023328
NABP1	0.023287
FMO5	-0.023286
DDX60	-0.023270
GNG11	-0.023224
CYP2B7P	0.023194
MGST2	0.023163
SATB1	0.023161
SAMD9L	0.023124
POU2F3	-0.023092
NEGR1	0.023014
GPX8	0.022993
XAF1	-0.022977
CDHR3	0.022966
ID1	-0.022965
TMEM26	-0.022953
FGF11	0.022846
CNIH4	-0.022784
ZNF217	-0.022760
TIMP1	-0.022701
ZNF462	0.022639
ST6GAL1	-0.022637
TMEM117	-0.022617
BFSP2	0.022570
PRKCE	0.022555
FOXK2	0.022528
SLC26A5	-0.022503
SLC41A2	-0.022486
AHNAK2	0.022424
CARS2	0.022394
LNPEP	-0.022320
CCDC58	0.022316
PRKACB	-0.022215
MX1	-0.022141
KCNMA1	-0.022093
REEP1	-0.022042
ECE1	0.022037
CAPN13	0.022031
DUSP5	-0.022029
SNORA60	-0.021999
JAG1	0.021992
EGF	-0.021952
SEMA3C	-0.021903
FBXO28	-0.021796
CASP14	-0.021703
IGFBP4	0.021686
GINS4	0.021655
FUT8	-0.021645
ZDHHC22	-0.021563
COX6C	-0.021536
CAPN9	0.021472
CLDN3	-0.021472
SRGAP3	-0.021433
GPHN	-0.021365
STK24	0.021348
PLCD4	-0.021280
TBC1D8	-0.021276
RAB29	0.021242
PTPRK	-0.021212
SEMA6A	0.021190
SGK3	-0.021182
IER3	-0.021139
RNU12	-0.021108
HCAR1	-0.021104
ART4	-0.021043
GMPR	-0.021041
OLFML3	0.021020
ATP11B	-0.021007
SLITRK5	0.021003
SLC9A2	-0.020993
FAM47E	-0.020990
BAI3	0.020936
PLSCR1	-0.020935
ROPN1L	0.020904
EPPK1	0.020894
ZNF750	-0.020838
NREP	0.020771
FLJ38379	-0.020762
PPP4R4	-0.020579
IRS1	0.020559
SLC9B2	0.020558
ELP2	-0.020491
TAF4B	0.020491
DOCK10	-0.020483
SENP2	-0.020479
SIDT1	-0.020474
EXOC6	-0.020464
IL5RA	0.020372
C9orf64	0.020363
PCDHB5	-0.020327
XCL1	0.020220
PTPRG	0.020139
KCNK2	0.020088
LDOC1	0.020014
EXT1	-0.019942
IFI6	-0.019927
ERICH3	-0.019883
ENPP1	-0.019863
LRRC28	-0.019851
CAMK2B	-0.019823
MED12L	-0.019816
CHST1	-0.019810
RPL37A	0.019789
FAM60A	0.019769
ERAP1	-0.019746
ID2	-0.019699
C9orf84	-0.019671
OXTR	-0.019617
ITGB8	-0.019595
CHAD	0.019549
ACSL1	-0.019517
KIF1A	-0.019514
CD22	0.019498
LARGE	0.019484
VAV3	0.019474
GALNT4	0.019458
PHTF2	-0.019441
LPAR1	-0.019436
RAB30	-0.019427
GP2	-0.019410
SCARNA4	-0.019391
SLC16A1	0.019305
SNORD1A	0.019293
GJC1	0.019293
C1GALT1	0.019281
SEPT3	-0.019266
GLTSCR2	0.019263
CSRNP3	0.019259
C10orf2	0.019197
LRRC34	-0.019183
PGLYRP2	-0.019183
SLC1A2	-0.019172
PLCB2	0.019152
CST9	-0.019143
FBXO32	0.019133
LY75	-0.019126
SEPT10	-0.019119
AR	0.019106
PVRL3	-0.019059
PCDHB15	-0.019054
MPPED2	-0.019036
KIAA0040	-0.019032
NRG4	0.019028
GJA1	-0.018978
SLC39A8	-0.018974
GREB1L	-0.018972
STOX1	-0.018970
DKK1	-0.018954
NOD2	0.018950
ZNF608	0.018927
SUSD1	-0.018927
HEY2	0.018890
MT1F	-0.018883
LETM2	-0.018861
SRPK2	0.018861
SQRDL	-0.018780
DENND1B	-0.018773
MIR30C2	0.018766
HECTD2	-0.018765
SCARNA23	-0.018754
TOX3	0.018739
SCNN1B	0.018727
MPDZ	-0.018694
SNORA1	0.018672
SPX	-0.018665
SPTBN2	0.018643
APOBEC3C	0.018628
SYTL4	0.018624
SEZ6L	0.018620
HSH2D	-0.018607
ACADSB	-0.018600
PTCHD1	0.018578
GSTM2	-0.018577
SLC6A11	0.018571
SNORA75	0.018566
CBX2	0.018565
NDST4	0.018561
GK	-0.018554
PERP	0.018523
CTSO	-0.018515
UCP2	0.018512
KCNK5	0.018500
BOP1	0.018499
PDCD10	-0.018473
MRPS25	0.018454
CDR1	0.018427
MXRA7	-0.018383
CUL4A	0.018365
SRM	0.018337
SNORD61	-0.018334
ANO1	-0.018317
MICB	-0.018268
ADAMTS1	0.018267
EDIL3	-0.018259
RMI1	0.018235
NCOA1	-0.018209
MATN2	0.018205
PCGF5	-0.018183
SNORD13P2	0.018100
KPNA3	0.018068
EDN2	0.018031
BACE2	-0.018026
ERBB4	0.018024
UBA7	-0.018018