!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 48 Hour
!organism	rat
!end_metadata
MYL2	-0.182829
ALDH1A1	0.175093
COL3A1	-0.170898
CYTB	-0.168503
PPP2R5A	0.151826
ND5	-0.146794
COL1A2	-0.134139
CASQ1	-0.131414
H19	-0.130656
PDK4	-0.129521
ACTA1	-0.126668
LGALS1	-0.124794
VIM	-0.124529
COX7A2	-0.120838
SPARC	-0.117972
CCNG1	0.117257
ATP2A1	0.112279
COL1A1	-0.108998
NDUFB3	-0.108220
FXYD1	-0.108005
POSTN	-0.107551
FABP3	-0.107462
ACADM	0.101925
NDUFV2	0.100197
LDHA	0.099735
CHRNA1	-0.097418
ND2	-0.096038
TUBA4A	-0.093648
JPH2	0.089094
MYL12B	-0.088072
FTL	-0.087366
MGST3	-0.087176
UCP3	-0.087074
HSPB6	-0.084424
NR4A1	0.084259
HSPA8	-0.082269
ANKRD1	-0.079228
RPL26	-0.078949
RPL10	-0.078934
TNNI1	-0.077710
TUBA1B	-0.076183
ACTC1	-0.075737
THBS4	-0.075423
UQCRC2	-0.075383
MYLK2	0.073403
RPS17	-0.073227
MGP	-0.071248
COX4I1	-0.071010
ACTN2	0.070211
MDH2	0.069506
ATP5H	-0.068604
RPL17	0.068175
PPP1CB	0.066454
YBX3	0.065808
SVIL	0.065631
PARK7	-0.065131
APOE	-0.065022
COX7B	-0.063531
UBC	0.063401
NDUFS7	0.063347
LDHB	-0.062827
SLC16A3	0.062533
NDUFB4	0.062432
MYBPH	0.062079
PPIA	-0.061665
PYGM	0.061609
PKM	0.059240
COX5A	0.058401
SEPW1	-0.058315
COX3	-0.055622
LUM	-0.055510
SCHIP1	0.054558
DYNLL1	-0.053546
CKM	-0.053024
CD63	-0.052993
RPL22	0.052608
CKMT2	0.052477
DNAJB5	0.052327
ALDOA	-0.052049
TCAP	-0.051774
RPS13	-0.051739
ACTB	-0.050990
RPL12	-0.049782
CTSV	-0.049728
MYL4	-0.049588
ACADL	0.049444
COL5A2	-0.048290
NDUFB9	0.048158
NDUFB2	0.048083
ENO3	-0.047620
NDUFA9	0.047334
ND4	-0.047093
NDUFA3	-0.046842
DDX3X	0.045185
RPSA	-0.044778
ATP1B1	-0.044551
MYL3	-0.044519
CTBP1	0.044471
VEZF1	0.043772
RAF1	0.043522
ACTA2	0.043129
PABPC4	0.043052
MYH7	-0.043022
ATP6	-0.042991
CA3	0.042599
MAP1LC3A	0.042199
RPS11	0.041352
MORF4L2	-0.040242
UCP2	0.040189
CITED2	-0.040045
DCN	-0.039917
CSRP3	-0.039741
MDH1	0.039458
MYH2	-0.039406
OAZ1	-0.038959
RPL37	-0.038691
MYBPC1	0.038104
PRKAR1A	-0.038003
FLNC	-0.037228
HSPB1	-0.037224
KLF9	0.037204
RPS10	-0.037159
NAPA	0.036075
PAICS	0.036068
TUFM	0.035852
RPL15	0.035604
NPHP1	0.035009
MPC1	-0.034927
PPP1R1A	0.034835
NDUFA8	0.034721
TECR	-0.034152
RPS16	-0.034002
SCN1B	0.033993
ATP5J	0.033940
HIBADH	0.033888
CLU	-0.033757
PPP1CA	-0.033724
CD151	-0.033710
UQCR11	0.033619
COX1	-0.033604
FAU	-0.033597
TPI1	0.033438
MYH1	0.033437
RPS21	-0.033301
NDUFAB1	-0.033255
ATP5B	0.033143
CTSB	-0.033047
NDUFC1	-0.033008
PSMD11	-0.032949
GOT1	-0.032859
MYADM	-0.032852
VDAC1	-0.032825
DHRS7C	0.032723
RPL6	-0.032612
H1F0	-0.032227
RXRG	0.032166
TMEM59	-0.032140
MMP14	-0.032051
ITGB1	-0.031547
EEF2	-0.030933
GNG5	-0.030653
RPL28	-0.030590
ATP5O	-0.030569
DLK1	-0.030273
DUSP1	0.030160
KCNJ11	0.030134
TMBIM6	-0.029948
PTGIR	0.029923
PGAM2	0.029843
CTSD	-0.029736
TST	0.029714
DES	0.029661
HRAS	0.029549
BGN	-0.029483
CD74	-0.029478
RPL7A	-0.029386
RPL13A	-0.029284
TUBA1A	0.029278
NEXN	0.029169
PEBP1	-0.029076
ZFP36L1	-0.029072
SLC41A3	0.029020
GRN	-0.028981
FLOT1	0.028712
CPE	-0.028666
EMP1	-0.028411
RPS14	0.028184
ACSL6	-0.028044
GABARAP	0.027938
TUBB	-0.027923
SNRNP70	0.027813
CAV1	0.027813
SDHAF2	-0.027776
DCAF6	0.027701
CAP2	-0.027535
PPM1A	0.027525
NDUFV3	0.027403
RPL18A	-0.027403
MFGE8	-0.027291
HADHA	0.027186
CAPZA2	-0.027081
ENO1	-0.027080
TNNT3	0.027039
NDUFA5	0.026978
EEF1G	-0.026855
FN1	-0.026852
COLQ	0.026734
SLC25A4	-0.026630
S100A4	-0.026441
HDLBP	0.026210
METAP2	0.026174
SLC6A8	0.026120
B2M	-0.026085
TUBA1C	-0.025930
GDI2	-0.025690
CACNA2D1	-0.025495
PSMC2	-0.025278
NSFL1C	-0.025249
RPS27A	-0.024793
UBE2G1	0.024774
RPS27L	-0.024722
TCN2	-0.024648
IVD	0.024561
GAA	-0.024320
PPIB	-0.024273
RPS12	0.024140
ATP5C1	-0.024136
NR1D1	0.024074
SNRPB	-0.023954
ALDH6A1	0.023777
PGK1	-0.023749
CPT1B	-0.023748
TNNI2	-0.023741
CISH	0.023631
PPP2R1A	-0.023507
USP19	0.023481
ECHS1	-0.023432
NDUFB8	-0.023324
S100A10	-0.023287
PDLIM1	-0.023093
KLC1	0.023073
PPP2CA	0.022957
RPS29	-0.022790
MYF6	-0.022782
DNAJA2	0.022753
RPL3	-0.022684
TMEM255B	0.022572
GMPR	0.022471
YWHAZ	-0.022124
LAMTOR1	-0.022093
IDH3G	0.022049
UBE2J2	0.022040
SOD3	0.021865
HADHB	0.021845
CYC1	0.021820
ARF1	-0.021768
FABP6	0.021743
SLC25A3	-0.021621
PSMC1	-0.021612
LOXL1	-0.021566
IGFBP6	0.021480
RRAD	0.021460
PTP4A2	0.021431
AMPD1	-0.021394
RPS23	-0.021381
TCTA	-0.021380
LTA4H	-0.021340
AHNAK	-0.021317
RPLP2	0.021313
SNRPN	0.021216
PSMB5	-0.021215
KCNC4	0.021127
NDUFS8	-0.021037
SOD2	0.020990
MAPK14	0.020900
HNRNPAB	0.020839
NDRG2	-0.020819
ANXA2	-0.020659
MAPKAPK3	0.020639
RPS26	-0.020608
KIF13A	0.020600
G0S2	-0.020511
HNRNPU	-0.020464
ITM2B	-0.020435
ANXA5	-0.020431
CST3	0.020378
PNRC2	-0.020338
EIF2S3	-0.020264
GPD1	0.020168
ZNRF1	0.020121
CNBP	0.020020
AK3	0.019983
PADI2	-0.019901
MYH6	-0.019793
TRIP10	0.019767
CRYAB	-0.019613
MYOC	0.019603
RPS9	-0.019572
PSMC3	-0.019497
NUDT4	-0.019480
CAMK2B	-0.019472
COX6A1	-0.019462
APRT	-0.019414
CBFB	0.019408
PTOV1	0.019294
MTDH	0.019269
MAPK6	0.019183
BSG	0.019117
ATP5D	-0.019057
NCL	-0.019025
DNAJA1	-0.018981
ANXA1	-0.018908
NDUFB5	-0.018702
FAM160B2	0.018560
PTPN3	-0.018530
EIF3D	0.018495
TAF6	0.018195
PSMB2	-0.018190
PSMA7	0.018170
PFKM	-0.017896
LDB3	-0.017817
PGM2	0.017780
PDHA1	0.017686
SMPX	0.017606
MYCBP2	0.017605
HK2	0.017494
GNAS	0.017398
CDC42EP3	0.017346
TIMP2	-0.017321
SH2B2	0.017252
PSMB6	0.017146
TUBB4B	-0.017128
CPQ	-0.017071
RCHY1	0.017048
BAG6	0.017033
ATP6V1F	-0.016970
PSMA2	-0.016935
RHOJ	0.016846
TNNC2	-0.016791
BTG2	-0.016753
SLC29A1	-0.016715
RPS4Y1	-0.016696
RPS7	-0.016628
PADI3	0.016627
YBX1	0.016613
SLC2A4	0.016564
MYH8	-0.016438
PMEPA1	0.016403
KLHDC3	0.016392
ANAPC5	-0.016380
VPS29	-0.016350
TXN2	0.016339
JUN	-0.016323
CXCL14	-0.016300
RPLP0	-0.016291
CHURC1	-0.016257
SDCBP	-0.016203
SPOP	0.016176
RPL18	-0.016156
CAPN3	0.016131
ATP2A2	0.016123
CD9	-0.016004
DLST	-0.015950
ATP6AP1	-0.015945
AKR1A1	-0.015906
GSTA5	-0.015885
PDHB	-0.015573
IL15	0.015549
C11orf73	0.015503
RPL23	0.015478
VCP	-0.015430
SLC37A4	0.015393
ALDH2	0.015373
RPS5	0.015334
PCOLCE	-0.015307
MTCH2	0.015277
ASPH	0.015269
AGTPBP1	0.015262
POLR3K	0.015183
ACO1	-0.015170
LTBP1	-0.015154
FAM160B1	0.015151
HSD11B1	-0.015063
SLC16A1	-0.014974
PGAM1	0.014918
EMB	-0.014872
EIF4E2	-0.014643
CLTA	0.014588
PRKCG	0.014579
ACSL1	-0.014420
PDYN	0.014418
MRFAP1	0.014418
VAMP5	-0.014409
SLC25A30	0.014385
AKT2	-0.014338
RAB11B	-0.014295
ATP5G2	-0.014235
RPL35	-0.014223
STMN1	-0.014220
MYL12A	-0.014199
ATP5A1	-0.014184
RPL9	-0.014171
PDIA3	-0.014171
CXCR1	0.014134
CTSK	-0.014091
TSPAN3	-0.014046
DECR1	0.014030
BTG1	-0.014018
GM2A	-0.014002
PRDX3	0.013984
NEU2	-0.013972
PSMB3	-0.013926
FMOD	-0.013895
MAFK	0.013808
CALR	-0.013806
EIF5B	0.013704
EGR1	-0.013613
NFYC	0.013606
APP	0.013601
ACADVL	0.013464
PRKAG1	0.013433
VAMP2	0.013394
PPP2CB	0.013393
TXNIP	0.013331
CCDC124	0.013103
TNNT2	-0.013089
IFRD1	0.013061
CRP	-0.013058
RPS15A	-0.013017
SERPINE2	-0.013006
PIK3CD	0.013001
ECH1	0.012965
SYNPO	0.012922
ITGA1	-0.012894
STAT5B	-0.012886
GSTK1	-0.012851
RPL11	0.012819
PDE4B	-0.012781
PRDX2	-0.012768
CSNK1D	0.012756
HELZ	0.012730
SLC28A2	0.012698
TRAPPC3	0.012698
CACNG1	-0.012693
ORAI1	0.012631
RPS3	-0.012629
VPS52	0.012593
AP4S1	0.012574
GSK3A	0.012569
COX6A2	0.012559
FLOT2	0.012553
UBALD1	0.012534
PPM1B	0.012527
KAT5	0.012510
PIK3IP1	-0.012482
ALPL	0.012475
CD1D	-0.012459
PPP3R1	-0.012455
MLLT3	-0.012438
ATP5F1	-0.012303
HIGD2A	-0.012253
VEGFB	0.012221
ZHX2	0.012211
CBX1	0.012172
PLK1	-0.012165
ADCY2	0.012147
GOT2	0.012084
TOM1L2	0.012078
IGBP1	0.012065
NDUFS1	-0.012049
GAMT	0.012033
PSAP	0.012020
LYZ	0.011988
YWHAE	-0.011981
SMAD3	-0.011967
PSMC4	-0.011965
NDUFC2	-0.011954
EIF4EBP1	0.011932
TRAPPC10	0.011919
SCARB1	-0.011901
PDP1	0.011891
TCEB1	-0.011888
PSMA6	0.011833
ARF4	-0.011806
ID3	-0.011803
RPL30	0.011801
KARS	-0.011762
IMP3	0.011759
SERBP1	-0.011746
DRD3	0.011734
F2R	-0.011728
KLHL41	-0.011707
JUP	0.011706
CD82	-0.011690
COA5	-0.011672
SOD1	-0.011652
GLUL	0.011652
DGKZ	0.011638
EEF2K	0.011622
KNG1	0.011563