!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Chlorambucil
!smiles	C1=CC(=CC=C1CCCC(=O)O)N(CCCl)CCCl
!drugbank_id	DB00291
!pubchem_cid	2708
!cell_type	NA
!organism	human
!end_metadata
HIST1H4C	-0.326433
PPA1	0.129528
HSPB1	0.114311
RARS	0.104173
RPL8	0.095786
HMGN2	-0.094815
FTH1P5	-0.089140
PSMD14	0.086366
HIST1H2BK	-0.083633
RPS20	-0.083092
MLLT11	0.080132
EIF3H	0.079714
RPS10	-0.078064
PRDX1	0.077782
PSMA4	0.077302
HSPA1A	0.077030
RPL34	-0.076411
HIST1H1C	-0.075623
CCT3	0.075045
ODC1	-0.073066
COX1	-0.071747
LBR	-0.070853
SOD1	0.070780
TPT1	-0.070165
ARL6IP1	0.069096
RPS5	-0.069027
HINT1	0.068335
VDAC2	0.068150
H2BFS	-0.068075
HIST1H2AC	-0.066478
PSME2	0.066276
RPLP0	-0.065834
RPL7L1	-0.065429
RPS3	-0.063971
POP5	0.063589
CSNK2B	0.063319
STRA13	0.062507
TUBB	0.061433
IFITM1	0.061172
KRT18	0.061033
RPS25	-0.060898
MRPS24	0.060662
DDX21	-0.058813
TRMT5	-0.058240
IARS	0.057685
FTL	-0.057577
HIST1H2BH	-0.057426
SNHG1	-0.057102
SUMO2	-0.057007
ANP32B	-0.056597
ATF4	-0.056516
SRP9	-0.056474
MRFAP1	-0.055309
RPL7A	-0.055025
RPS13	-0.054229
C12orf57	0.054159
SNRPG	-0.053583
RPS2	-0.053476
LINC00998	-0.053451
TOMM5	0.053323
CLIC1	0.052945
NOP10	-0.051785
NDUFA13	0.051603
UQCRH	-0.051505
ACTB	-0.051147
RPL21	0.050815
ATP5G3	-0.049913
AP2S1	0.049904
DDX1	0.049297
SNRPD3	0.048495
GHITM	0.047674
NDUFA8	0.047563
PSMC6	0.047094
CDK1	0.047025
PSMC3	0.046994
VAMP7	0.046724
UQCRFS1	0.046494
GLRX2	0.046463
FEN1	-0.046362
UBL5	0.046293
UFD1L	0.046259
RAB13	0.045927
NDUFV2	0.045782
RPL3	-0.045554
RPL26	-0.044914
DYNC1I2	0.044830
SHFM1	0.044619
TFRC	0.044132
RSL24D1	-0.044007
PCBP1	-0.043619
PRDX4	-0.043550
RPS18	-0.043531
EEF2	-0.043520
RPL35	-0.043446
RPS3A	-0.043095
DARS	-0.043070
FADS1	0.042945
GTSF1	0.042786
GDI2	0.042685
TMEM14C	-0.042537
RPS27	-0.042347
PPIA	-0.042333
ADH5	0.042246
CTCFL	-0.042202
HSBP1	0.041976
NOP58	-0.041846
PSMA5	0.041776
ZWINT	-0.041665
NDUFAB1	0.041659
DPM1	-0.041598
SDF2L1	0.041396
NACA	-0.041364
SPCS1	0.041082
CACYBP	0.040911
TMA7	0.040341
NOP56	-0.040102
ATP5H	0.039748
RPS12	0.039663
SLIRP	0.039617
UBC	-0.039422
SRGN	0.039174
COX8A	-0.039101
COX6B1	0.038477
RHOA	0.038395
HLTF	0.038275
PSMG1	-0.038112
ACLY	0.037963
RPS26	-0.037869
RPS11	-0.037863
RPL30	0.037697
PFDN5	0.037562
ARL5A	-0.037384
C19orf53	0.037368
IDI1	0.037260
B2M	0.036839
SEC61G	0.036721
EMP3	0.036709
HADHB	0.036536
TAF9	0.036535
SRSF2	-0.036510
FDFT1	0.036493
COX7C	-0.036491
DNAJA1	0.036464
PRDX6	0.036412
RPL36	-0.036142
UBA2	-0.035931
HSD17B10	0.035874
RPL23A	-0.035589
APOBEC3C	0.035580
HK1	0.035503
LMO2	-0.035263
MDH1	0.035076
KCNH2	-0.034901
SNRPA	-0.034787
COX6A1	0.034626
MAD2L1BP	0.034436
YWHAZ	0.034294
POLR2G	0.034232
GSTO1	0.034225
SSR4	0.034109
CMC2	0.033745
NET1	-0.033682
CREG1	0.033587
ANXA1	0.033521
YWHAB	0.033420
RHAG	0.033264
PPIL1	-0.033169
ZNF280A	0.033158
UBB	-0.032987
RAP1B	0.032900
GTF3C6	0.032837
DLK1	0.032802
UBE2N	0.032755
MRPS30	0.032561
KPNB1	-0.032441
TMX2	-0.032042
PRR13	0.031964
PFDN2	0.031957
VCL	0.031752
SET	-0.031742
THOC1	-0.031574
FAM162A	0.031212
RPL39	0.031143
HSP90AA1	0.031124
RPL37A	-0.031102
GLO1	0.031064
LAPTM4A	0.031036
RAN	-0.031022
MYL4	0.030966
RPL7	-0.030948
ADSL	0.030794
BST2	0.030738
HIST1H2BD	-0.030536
CCT6A	-0.030520
PGAM1	0.030402
MPP1	0.030373
DBI	0.030200
AURKA	0.030137
NDUFB5	0.030023
GPI	0.029837
LARP1	-0.029698
ENOPH1	-0.029641
ERH	0.029636
C14orf166	0.029548
KRT10	-0.029505
NDUFA12	0.029305
PSMB5	0.029287
EEF1B2	0.029274
SLC38A2	0.029174
MDH2	-0.029133
PRAME	0.028989
DCTPP1	0.028897
PTMA	-0.028840
FKBP2	-0.028611
UAP1	0.028521
RPS6	-0.028519
NDUFS2	0.028492
TUBB2A	0.028462
TRIM28	-0.028426
BCAS2	0.028373
ZMPSTE24	0.028315
STARD7	-0.028250
TRMT112	0.028130
CBX1	0.028104
RPLP1	-0.027943
DDX39A	-0.027904
EEF1E1	0.027894
KIAA0101	-0.027861
SCNM1	-0.027801
EIF3E	-0.027760
GBAS	-0.027704
UBE2T	0.027633
SF3A3	-0.027608
TMEM126A	0.027571
RPS4X	-0.027404
PSMB3	-0.027383
TUBA3C	-0.027371
DAD1	0.027354
NCOA4	0.027345
SPAG5	-0.027279
MSMO1	0.027248
PTTG1	-0.027241
TAF7	0.027226
PSMA7	0.027217
TPRKB	0.027201
EMG1	-0.027116
EIF2B3	0.027028
ATP5G2	-0.026897
MTCH1	0.026859
HMMR	0.026826
TRAPPC4	0.026795
MYC	0.026710
NDUFA9	0.026642
POMP	-0.026629
PAICS	0.026585
SNHG19	-0.026534
CHST2	0.026519
UBE2S	-0.026513
HBE1	0.026338
KIF20A	-0.026201
TTC1	0.026140
RAD23A	-0.026101
COX7A2L	0.025969
NDUFB9	-0.025949
DAP3	0.025904
PSMA1	0.025829
YTHDF2	-0.025824
ORC3	0.025620
ATP5E	-0.025599
HBD	-0.025593
HN1L	0.025559
GABARAPL2	0.025549
MRPS35	0.025516
CMSS1	-0.025475
KHDRBS1	0.025464
ECI2	0.025434
MRPS6	0.025423
SNX3	0.025405
PSMD13	0.025388
FIS1	0.025362
PRMT1	0.025316
TIMMDC1	0.025275
STIP1	0.025238
PSMD12	0.025227
CDC20	-0.025192
RPS19	-0.025174
TYMS	-0.025162
TALDO1	0.025151
RAB10	0.025150
ILF2	-0.025131
MRPS33	0.025126
CFL1	0.025056
HNRNPK	-0.025028
MRPS27	-0.025001
PAXIP1	-0.024958
OXA1L	0.024954
NSMCE1	0.024924
MORF4L1	-0.024756
IARS2	0.024750
DANCR	-0.024732
NCAPG2	0.024681
WDR12	-0.024647
DHX15	0.024631
DYNLL1	-0.024619
HSP90AB1	0.024551
NIP7	-0.024512
PHB	0.024415
NUDC	0.024389
MKNK2	0.024372
SSR3	0.024363
COX5B	0.024317
MAGOH	-0.024316
UQCRC1	0.024018
HDDC2	0.024002
PSME1	0.023946
RAB11A	0.023934
UBE2E3	-0.023858
HNRNPA1	-0.023801
TMSB10	-0.023801
SSR2	0.023737
MLH1	0.023731
SNHG16	0.023669
C12orf45	0.023574
RPL14	-0.023538
BLMH	0.023507
C1QBP	-0.023482
ARL4A	0.023420
HIST1H3H	-0.023317
H2AFZ	-0.023232
NDUFC1	-0.023232
UQCRQ	0.023185
ACTL6A	-0.023179
NAF1	-0.023176
SELT	0.023140
TMEM50A	0.023091
JAGN1	-0.023083
WDR74	-0.023019
ATP5I	-0.022996
DIRAS3	-0.022981
HSPH1	0.022980
SMIM15	0.022958
EIF6	0.022931
ATP6V1F	-0.022866
ACN9	-0.022687
C11orf48	0.022657
PTGES3	-0.022618
LINC01029	0.022594
CYFIP1	0.022571
PAIP2	0.022559
CTSL	0.022512
SERPINH1	0.022469
SWI5	0.022421
ATP6V1E1	0.022408
CRELD2	0.022302
PRR11	-0.022260
NDUFS6	0.022235
PTBP1	-0.022188
CCDC58	0.022182
DDX47	-0.022163
PUS7	0.022160
HIST1H2BF	-0.022144
BOLA3	0.022131
CCT2	0.022101
MEF2C	0.022099
LAMTOR5	0.022041
GRHPR	0.021994
MRPS23	0.021950
CORO1C	0.021908
RPS17	-0.021879
CHCHD1	-0.021838
AHCY	0.021791
RPL36A	-0.021754
ZRANB2	0.021750
HSPD1	0.021700
HIST1H2BI	-0.021569
ARMC10	0.021534
ISOC1	-0.021502
PNP	0.021438
HMGN1	-0.021428
ATP5F1	0.021413
RAC2	0.021372
UXT	-0.021359
YWHAG	-0.021325
ZFPM2	0.021292
ATP6	0.021261
TXNL1	0.021258
BAG6	-0.021255
ATP1B3	0.021243
TCEB2	0.021204
STYXL1	0.021147
HNRNPDL	-0.021084
PAPD7	-0.021058
TRIM44	-0.020998
HBBP1	0.020975
ICAM3	0.020955
PSMD2	0.020955
RPIA	-0.020948
LAPTM4B	0.020945
KLHDC8B	0.020902
CAP1	0.020900
OAZ1	-0.020848
EIF1B	-0.020830
SKA2	0.020825
MAGEA6	-0.020818
AIFM1	0.020794
LGALS1	0.020696
CANX	0.020652
LINC01003	-0.020649
ATP6V1B2	0.020645
TUBA3D	-0.020572
PSMD4	0.020570
CCND3	0.020538
C21orf33	0.020538
C2orf69	0.020492
CUTA	0.020361
MTHFD1	0.020330
PPT1	0.020316
CENPK	-0.020307
ECHDC1	0.020261
COPS2	0.020252
EXOSC9	-0.020247
CSE1L	0.020231
CETN3	0.020228
TUBA1C	-0.020106
LTA4H	0.020089
ROMO1	0.019916
EAPP	0.019777
FGF13	0.019732
BMI1	-0.019705
DHCR24	0.019622
CHCHD2	-0.019606
HMGB2	-0.019593
DHRS2	-0.019578
METTL5	-0.019557
MUT	0.019544
TMEM167A	0.019540
SEPW1	0.019539
TMEM99	0.019529
MYCBP	0.019450
ATPIF1	-0.019392
MAPK6	0.019371
RFWD2	0.019349
PHB2	-0.019316
SEC24B	0.019267
SMS	-0.019257
MPC2	0.019247
ZW10	0.019237
RELN	0.019221
FAM96B	0.019213
SLBP	-0.019176
ADI1	0.019173
UBE2K	0.019089
HMGB3	-0.019030
MRPS18B	-0.018992
PSMC1	0.018989
LOC100505812	-0.018963
EPRS	0.018960
PSMB6	0.018951
MRPL11	-0.018849
VAMP8	0.018848
CBFB	0.018813
CWC15	0.018806
MRPL54	-0.018795
YBX1	-0.018761
GPX4	0.018760
CSTB	0.018737
COX3	-0.018731
FH	0.018715
LSM3	0.018683
MSH2	0.018660
PSMB4	0.018657
NDC80	-0.018657
ITGB3BP	0.018652
ACTN4	-0.018639
EIF1AX	-0.018587
PSMD11	0.018582
RPL24	-0.018546
YWHAE	0.018543
POLR3K	0.018522
TXN2	0.018507
RPSA	0.018493
BIRC2	0.018454
JTB	-0.018454
HSPA5	0.018375
RPL5	-0.018298
UQCC3	-0.018260
PIM3	-0.018249
POLR2J	0.018240
MRPS36	0.018221
MT1HL1	0.018169
TBCA	0.018093
LSM2	-0.018053
LSM5	-0.018029
RPL27	-0.018015
GLA	0.017983
ST13	0.017929
STXBP5	-0.017919
PTRH2	0.017893
RPS27A	0.017889
WARS	0.017855