!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	4-Hydroxytamoxifen
!smiles	CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
!pubchem_cid	449459
!cell_type	MCF7 breast cancer cells - 500nM
!organism	human
!end_metadata
PABPC3	-0.257492
IER3	0.257331
LCN2	-0.182696
NQO1	-0.180176
TFF1	-0.175852
AGR2	0.161032
LXN	-0.128241
NFKBIA	-0.117176
TPD52L1	0.116223
PRDX1	-0.115189
KRT18	-0.110736
MIF	0.109043
RPL36A	0.103623
RPL11	0.096604
LDHA	0.093402
FTH1	-0.092871
SERPINA3	-0.092499
PSMA6	-0.092216
FTL	0.085630
KRT19	0.085244
MYL12B	-0.083035
HSPB1	0.082030
RPS25	0.081517
LAPTM4A	0.081362
TBCA	0.080850
RPL24	0.078869
COX1	-0.076288
CSTA	-0.076087
MYL12A	0.074310
S100A9	-0.072451
DBI	0.072143
RPL41	-0.071116
RPS14P3	0.071079
AKR1C3	-0.070838
NHP2	0.068366
SNRPF	0.068118
RPS18	0.067862
S100P	-0.066352
RPL27	0.066200
TMEM64	0.065236
COX8A	0.064441
CFL1	-0.064049
ATP6	-0.063834
UBC	-0.063782
ADAR	-0.061664
HSP90AA1	-0.061442
RPS20	0.061125
SULF2	0.061110
TCEAL4	0.060749
ID1	-0.059096
ATP5L	0.058866
TAX1BP3	-0.058691
RPS13	0.058286
TRIM16	-0.057489
CLIC3	0.057348
COX6C	-0.057221
RND1	-0.057168
BAMBI	-0.057145
SNRPD2	0.054935
FAU	0.054670
SLIRP	0.053853
IFI6	-0.053728
NDUFA1	0.053726
ISOC1	0.053267
ERH	0.052166
CKS2	0.052004
HSPA1A	0.051688
COX7A2	0.051574
USMG5	0.051090
FBP1	-0.049648
IGFBP3	-0.049464
NDUFAB1	0.049233
AKR1C2	-0.049004
HSP90AB1	-0.048400
UQCRH	0.048191
GGCT	0.047991
GATA3	-0.047672
RPL13A	0.047575
CD63	0.047567
CYP1B1	-0.046858
HLA-A	-0.046149
HLA-DRB1	0.045788
SLC9A3R1	0.045304
RPL19	0.044093
OST4	0.043995
TMEM258	0.043620
BCAS3	-0.042820
BZW2	-0.042698
DAD1	0.042512
SEC61B	0.041775
LGALS3	-0.041595
NPC2	0.041371
RPS19	0.040992
RPS29	0.040798
ARPC3	0.040422
RPSA	0.040171
NACAP1	-0.040145
RPL36AL	0.040086
NFKBIZ	-0.040013
PRDX4	0.039437
ATP6V1F	0.039250
ATP6AP1	-0.038888
C14orf2	0.038840
HMGN3	0.038706
RND3	-0.038600
CA2	0.038416
C14orf166	0.038308
ETFA	-0.038100
RPL29	0.037940
HMGN2	0.037432
COX7C	0.036975
RPS4X	-0.036564
ATP5B	0.036564
AGR3	0.036468
SLC39A6	-0.036177
MRFAP1	-0.036006
RPL30	-0.035967
KRT8	-0.035781
CHCHD2	0.035749
YWHAB	-0.035689
BCAS2	-0.035621
RPL34	-0.035481
CXXC5	0.035295
ATP1B1	-0.035228
PRDX5	0.034921
GPX4	0.034839
EIF5	-0.034588
KRT80	-0.034470
HSPA8	-0.034246
PTTG1IP	-0.034177
ISG15	-0.034037
NDUFB1	0.033884
CHCHD1	0.033553
RAC1	-0.033520
EBPL	0.033166
ATP5J2	0.032835
KPNA2	0.032609
DDIT4	0.032596
KYNU	-0.032446
RPL6	0.032432
POLR2J	0.032304
UQCRB	0.031775
TRMT112	0.031730
VAMP8	-0.031568
IER5	-0.031469
JTB	0.031013
GPRC5A	-0.030787
TMA7	0.030759
FAM102B	-0.030633
SDCBP	-0.030541
SCCPDH	-0.030472
EFNA1	-0.030295
C20orf24	0.030276
PABPC1	-0.030222
MAGED1	0.030210
HEATR6	-0.030205
ENO1	-0.030014
RPL7L1	-0.029841
UQCR10	0.029374
CFB	-0.029021
STARD10	0.028974
DPM1	0.028884
CRABP2	-0.028753
UBA52	0.028653
MRPS24	0.028641
DDX5	0.028639
TPM1	0.028568
ATP5J	0.028449
GABARAP	0.028402
NAP1L1	0.028326
MTCH1	0.028264
REEP5	-0.028243
RPS23	-0.028211
RPL12	0.028138
HIGD2A	0.028121
TSPAN13	0.028089
PKIB	0.028077
RPS6	0.027620
IFIT1	0.027585
RPL21	0.027562
MARCKSL1	0.027560
MIR21	-0.027521
RBBP7	0.027170
ECI1	0.026945
EIF3H	-0.026858
TGFBI	-0.026835
IFI27	-0.026783
SF3B5	0.026635
HSPH1	-0.026477
BNIP3	0.026450
S100A8	-0.026387
PPIB	0.026368
ANXA9	0.026304
NDUFA12	0.026156
MDH2	0.026075
FAM213A	0.026032
KIAA0101	0.026010
RPL36	0.025946
YWHAZ	-0.025920
RPS8	-0.025913
C19orf33	0.025749
TRIM37	-0.025695
PAPSS2	-0.025656
TFF3	-0.025574
NDUFB9	0.025566
HINT1	0.025559
PLP2	0.025438
S1PR3	-0.025287
COX7A2L	0.025279
EIF3E	0.025227
MALAT1	-0.025004
RPS26	0.024997
HIF1A	0.024990
IFITM2	0.024951
CEACAM6	-0.024907
ATP5G3	0.024901
RASGRP1	0.024766
BASP1	-0.024640
CD24	-0.024619
NDUFB4	0.024608
GAS5	0.024532
BRI3	0.024485
GNB2L1	-0.024091
NGFRAP1	-0.024084
RPL17	0.024039
CYB561	0.024011
RPL22	0.023883
KRTCAP2	0.023862
COX16	0.023802
TMED10	0.023751
NOP10	0.023673
EMC2	0.023653
RPS27A	0.023625
ID3	-0.023574
BPIFA4P	-0.023454
OSTC	0.023454
MGST1	0.023383
MLPH	0.023241
FBL	0.023220
EMC4	0.023211
NEAT1	0.023165
ATP5G1	0.023104
TMEM14A	0.023047
EPAS1	-0.022969
S100A10	0.022948
ATIC	-0.022935
PRKAR1A	-0.022885
TMEM14B	0.022812
FTSJ3	-0.022804
COX7B	0.022779
PSMC6	-0.022712
RASEF	-0.022705
SNHG8	0.022684
ATP5I	0.022623
PDCD10	0.022531
LAMTOR4	0.022529
DKK1	-0.022514
ACSL3	-0.022479
CBWD1	0.022448
DPY30	0.022424
SLC31A2	-0.022379
BLVRB	0.022308
GFRA1	0.022299
SAT1	-0.022293
TMEM167A	0.022120
CAP1	-0.022114
PFDN5	0.022074
GPR56	0.021999
RAB25	0.021950
SDC4	-0.021874
HADHB	-0.021856
TXNIP	0.021842
TMBIM4	0.021811
RPS27	0.021792
GSTM3	-0.021788
SLC25A6	0.021771
PPP3CA	-0.021692
NEDD8	0.021624
ERMP1	-0.021590
SNRPE	-0.021481
RPLP1	0.021444
PTTG1	0.021431
LASP1	0.021412
MZT2A	0.021310
PLOD2	0.021309
RPS6KB1	-0.021271
IFITM3	-0.021237
ANP32B	-0.021180
SLC2A6	-0.021102
COX6B1	0.021024
POLR2I	0.021000
IGFBP5	-0.020997
RAP2C	0.020972
DDR1	0.020960
ARPC1A	0.020941
PFN1	0.020873
TOP2B	-0.020870
TOP1	-0.020827
DYNLT3	0.020821
H2AFZ	0.020820
STAU1	-0.020814
WWP1	-0.020746
EEF1B2	-0.020727
SLC12A2	-0.020686
RAB9A	-0.020663
ATRAID	0.020642
SNHG5	0.020500
SUB1	0.020494
AP1S1	0.020460
SLC35A1	-0.020444
JUP	-0.020418
HLA-C	-0.020272
MRPL36	0.020268
MRPL33	0.020257
RPL14	0.020242
DSP	-0.020240
EEF1A1	-0.020231
HES1	0.020117
CDIPT	-0.020087
RPS3	0.020073
PMEPA1	-0.019960
AKR1C1	-0.019952
ABCC3	-0.019942
ATP5C1	0.019855
BPIFA1	-0.019851
LAP3	-0.019821
ELOVL7	-0.019806
NDUFA4	0.019780
RPL26	0.019647
UQCRFS1	0.019615
MYC	0.019603
PDLIM1	-0.019599
SOX4	-0.019585
NET1	-0.019520
CDK4	0.019514
PSMA4	0.019378
RPL31	0.019286
TMEM205	0.019284
SLC6A14	0.019283
SLC38A1	0.019231
DNAJB11	0.019199
EPB41L4A-AS1	0.019198
TALDO1	-0.019183
LAMTOR5	0.019123
TXN	0.018881
CTBP2	-0.018868
TMEM147	0.018848
DDX47	-0.018813
B2M	-0.018622
SNORD104	0.018537
DLG5	0.018509
NME1	0.018500
COX5A	0.018479
APPBP2	-0.018441
RPS5	0.018434
EEF1G	0.018431
PLK2	-0.018374
PDIA6	0.018269
PGRMC1	0.018263
ZFP36L1	-0.018225
PSMC5	-0.018150
LAPTM4B	0.018150
ARMCX6	0.018128
CSTB	-0.018068
RNASEK	0.018058
DSTN	0.018035
COX6A1	0.018000
PPP1CC	0.017996
POLR2L	0.017978
ND2	-0.017952
UBE4A	-0.017944
CYP1A1	-0.017844
BPIFB1	-0.017843
CAB39	-0.017801
IFNGR1	-0.017798
DHRS3	-0.017788
SNRPD3	0.017781
EEF2	0.017753
ERP29	0.017747
NPTN	0.017716
HSPE1	0.017608
RPL13	0.017544
NANS	-0.017486
NEDD9	-0.017451
VMP1	-0.017424
RPL8	-0.017414
SCRIB	-0.017365
TNFRSF21	-0.017274
RPL15	0.017206
SCP2	0.017196
RPL35	0.017175
C14orf119	0.017163
FAM214A	-0.017128
GPD1L	0.017125
MYO1B	-0.017026
C6orf48	0.017025
C19orf10	0.017019
ATP5F1	-0.016975
RAD23B	-0.016932
IFITM1	0.016917
LITAF	-0.016854
PHACTR2	-0.016840
TIMP3	-0.016794
PHB2	0.016748
BCAP31	-0.016685
NSA2	0.016677
NDUFA13	0.016676
CERS2	0.016647
SCRN1	-0.016631
TMSB10	0.016620
PCBP1	0.016619
CA12	0.016598
SNRPB	0.016585
SHFM1	0.016581
UQCRQ	0.016477
RAN	0.016454
GDF15	-0.016372
CUTA	0.016320
DYNLL1	0.016316
CD47	-0.016270
ABAT	0.016214
KARS	0.016211
NCOA3	-0.016197
PSMB1	0.016176
MICA	0.016158
RPLP0	-0.016158
TCF25	-0.016051
MAGED2	0.016035
RPS16	0.016032
TKT	0.016020
VKORC1	0.015984
TPT1	-0.015956
TMED9	0.015919
TUBA1B	-0.015888
ALDH1A3	-0.015873
NUCB2	0.015854
TMEM208	0.015829
PSMA5	-0.015771
CD9	-0.015769
ACTG1	-0.015766
LINC00052	0.015749
COX5B	0.015730
FIS1	0.015723
ARPP19	0.015701
PRR13	0.015676
NTN4	-0.015669
RABAC1	0.015659
FAM220A	-0.015656
TUBB2A	-0.015649
ACTB	-0.015642
PGAM1	-0.015633
KLF4	-0.015627
ATP5E	0.015601
NDUFB11	0.015518
CLTC	-0.015445
CDKN2B	-0.015426
CCND1	-0.015422
PSME2	-0.015399
SRP19	-0.015390
EVL	0.015387
PPM1G	-0.015324
CEBPD	-0.015322
RPL37A	-0.015307
C6orf141	0.015263
GCH1	-0.015258
TFPI2	0.015150
NDUFS3	0.015147
SLC35B1	0.015124
NOP58	0.015034
AARS	-0.014993
GABBR2	-0.014869
RPS11	0.014855
SNHG19	0.014829
EIF4A1	-0.014817
GTF3C6	0.014815
PSAP	-0.014653
ELF3	-0.014650
GAPDH	0.014642
AUP1	-0.014587
ATP9A	-0.014583
IMP4	-0.014581
ZNF146	-0.014566
UGDH	0.014538
UQCR11	0.014516
CSRP1	-0.014492
NDUFV3	0.014443
MRPL14	0.014426
DUT	0.014406
DUSP4	-0.014400
WRB	0.014389
TFAP2C	-0.014359
SHISA2	0.014351
DYNLT1	0.014348
ARL8B	0.014330
ZG16B	-0.014305
PPIA	0.014266
CTSV	0.014240
TUFT1	-0.014239
SLC38A6	0.014218
NME3	0.014213