!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell_type	MCF7cells
!pert_name	ICI-182,780(Fulvestrant)
!pert_id	PubChemCID:104741
!organism	human
!pert_type	chemical
!end_metadata
RASGRP1	-0.093763
MCM10	-0.093737
SLC6A14	-0.092006
MGP	-0.081265
STC2	-0.075823
STC2	-0.075493
DTL	-0.073903
SOX3	-0.072737
UHRF1	-0.072199
ZNF367	-0.070845
MYBL1	-0.066201
CALCR	-0.066189
RMST	-0.062398
SULF1	-0.061414
RRM2	-0.059199
GINS2	-0.058758
SULF1	-0.057801
NT5E	-0.057087
GFRA1	-0.056354
GFRA1	-0.056278
LINC00173	-0.055822
ELOVL2	-0.054813
CXCL12	-0.054289
NPY1R	-0.054119
SULF1	-0.053621
RERG	-0.053098
RRM2	-0.050933
ELOVL2	-0.050902
MYB	-0.049974
SHCBP1	-0.049799
RBM24	-0.048356
ABCA12	-0.047377
GPR68	-0.047286
GFRA1	-0.046877
PGR	-0.046754
CDCA7	-0.046027
RAMP1	-0.045705
ADCY1	-0.045206
DSCC1	-0.045072
ADCY1	-0.044261
AGR2	-0.044085
PCP4	-0.044001
MCM5	-0.043153
CA2	-0.043145
FHL1	-0.043024
RERG	-0.042883
CD44	-0.042226
HSPB8	-0.041894
EPS15L1	-0.041658
CENPU	-0.041646
COL12A1	-0.041380
STARD13	-0.041323
INPP4B	-0.041032
CCNE2	-0.040995
OLFM1	-0.040882
CDC6	-0.040719
MAOA	-0.040475
PLIN5	-0.039865
SPC25	-0.039750
BLM	-0.039570
HMCN1	-0.039516
FOS	-0.039447
TK1	-0.039402
TYMS	-0.039333
ALDH1A3	-0.038847
SYTL5	-0.038647
ARHGEF28	-0.038292
PPM1K	-0.038002
SCUBE2	-0.037904
C6orf141	-0.037855
WISP2	-0.037180
CDC6	-0.037122
CD44	-0.036968
MND1	-0.036852
ATP2C2	0.036830
WIPF1	-0.036742
MREG	-0.036499
DSCAM	-0.036487
MYOF	-0.036330
NT5E	-0.036309
PBK	-0.036271
OIP5	-0.036194
ATAD2	-0.036106
TGFBI	-0.035871
PPFIBP2	0.035552
MALRD1	-0.035467
TYMS	-0.035213
CDC45	-0.035043
PDP2	0.035027
MYOF	-0.034957
RAD51AP1	-0.034936
SGPP2	0.034858
CENPK	-0.034841
CXCR4	0.034794
ATP2C2	0.034573
EXO1	-0.034535
DDIAS	-0.034436
DTL	-0.034076
GREB1	-0.033895
COL12A1	-0.033671
MICB	-0.033558
ITGB6	-0.033474
CD44	-0.033452
CXCR4	0.033037
ANLN	-0.032616
FANCI	-0.032613
GPATCH2	0.032522
ATAD2	-0.032450
ACHE	0.032132
ANKRD35	0.031704
CD44	-0.031678
ACHE	0.031598
CD44	-0.031517
C6orf141	-0.031356
MELK	-0.031346
TRIP13	-0.031031
TK1	-0.030946
PDCD4-AS1	-0.030944
MYOF	-0.030744
EGR1	-0.030689
TPD52L1	-0.030673
WIPF1	-0.030502
HELLS	-0.030268
ESPL1	-0.030145
ITPK1-AS1	-0.030040
MCM2	-0.029961
MTFR2	-0.029927
FHL2	-0.029857
FEN1	-0.029796
NRK	0.029676
CD44	-0.029553
MYBL2	-0.029440
MREG	-0.029419
MALAT1	0.029366
KIAA0101	-0.029240
ORC6	-0.029157
POLE2	-0.029038
HAUS1	-0.028990
INPP4B	-0.028938
FEN1	-0.028822
S1PR3	0.028775
ANLN	-0.028750
CXCR4	0.028728
CDCA5	-0.028715
CDK1	-0.028611
CDK1	-0.028603
EPS15L1	-0.028522
HINT3	0.028517
BRCA1	-0.028383
MKI67	-0.028345
NDC80	-0.028293
ITGB5	-0.028223
CHEK1	-0.028194
SYNPO2	-0.028094
NT5E	-0.027997
CD44	-0.027992
AGR2	-0.027901
PCNA	-0.027895
MKI67	-0.027839
WIPF1	-0.027693
NCAPG2	-0.027653
AMFR	-0.027628
CHEK1	-0.027566
BRCA2	-0.027513
CENPU	-0.027503
CAP2	-0.027255
CDT1	-0.027237
PLK4	-0.027204
INPP4B	-0.027175
GABBR2	-0.027113
CISH	-0.027036
RFC4	-0.027002
BARD1	-0.026760
ALDH4A1	0.026651
AURKB	-0.026644
MAD2L1	-0.026638
IL1R1	0.026558
TPD52L1	-0.026496
WDHD1	-0.026495
PRSS23	-0.026483
GINS1	-0.026419
LGI1	-0.026315
EGLN3	-0.026247
KIF15	-0.026109
SCNN1A	-0.026020
FANCD2	-0.025923
TULP4	-0.025843
ATAD2	-0.025827
PLOD2	-0.025812
FANCI	-0.025462
CAP2	-0.025403
PPM1K	-0.025397
LDLRAD4	-0.025277
TMEM64	-0.025202
GINS3	-0.025146
FAM83D	-0.025009
RAD51	-0.024995
DSCAM	-0.024778
BCL3	0.024665
NPY5R	-0.024647
IFIH1	0.024602
SUSD4	-0.024570
SLC22A4	0.024454
CDK1	-0.024341
MORF4L2-AS1	0.024339
MCM6	-0.024270
NEDD4L	0.024262
FAM110B	0.024234
OAS3	0.024159
FAM13A-AS1	-0.024128
TCEA3	0.024066
LRP2	0.024032
DSCAM	-0.024010
SGK3	-0.024005
SYNPO2	-0.023980
GMNN	-0.023950
BIRC5	-0.023943
ZNRF1	-0.023870
LPP	0.023833
UGCG	-0.023796
CEP55	-0.023766
TEX14	-0.023607
SOX9	0.023582
RAB31	-0.023562
MIR4296	-0.023534
PLOD2	-0.023445
IGF1R	-0.023433
SUSD4	-0.023430
MAN1A1	-0.023387
SIK3	0.023376
BIRC5	-0.023277
IRS1	-0.023262
TMEM64	-0.023250
CACNG4	-0.023184
SLC4A8	0.023169
ATP6V0A4	0.023094
FUS	0.023082
GEM	-0.023070
E2F7	-0.022938
UBE2F	-0.022911
IGF1R	-0.022883
GRHL3	0.022881
TMEM17	0.022874
SLC25A25	-0.022841
LOC100506325	-0.022803
LGALS3	0.022779
COL5A1	-0.022703
MYO16	-0.022690
RAPH1	-0.022689
CD44	-0.022645
TMTC3	-0.022585
PGM2L1	-0.022571
ARHGAP18	0.022570
KCNJ2	0.022556
COL21A1	-0.022546
MFAP3L	0.022504
NRIP1	-0.022502
RUNX2	-0.022490
DRD1	0.022450
MCM10	-0.022360
SUSD2	0.022275
ZNF516	-0.022264
CENPU	-0.022227
SPATA17	0.022184
PKIB	-0.022179
ACACB	-0.022134
SMG7	0.022123
CENPW	-0.022104
CAMK1	-0.022019
C1orf226	-0.021975
IRS1	-0.021970
UGCG	-0.021838
CCDC33	0.021826
AP1S2	-0.021816
HELLS	-0.021801
SUZ12	-0.021796
GPATCH2	0.021721
PRORSD1P	-0.021711
LINC01004	-0.021700
SMAD9	-0.021622
MED13L	-0.021558
CAV1	-0.021542
MAP2K5	0.021505
BRIP1	-0.021505
YBEY	-0.021455
ALDH6A1	0.021397
NCAPG	-0.021344
PRKAB2	-0.021340
ERP27	-0.021338
KCNN4	0.021334
ALMS1	-0.021285
DHX37	-0.021259
CENPA	-0.021253
ABCA1	0.021233
PFKFB3	-0.021201
MCM3	-0.021059
MUC1	0.021057
LRP8	-0.021030
C9orf3	-0.020978
THSD4	-0.020962
RPS16P5	-0.020956
ANKRD34A	0.020954
ATAD2	-0.020913
VIPR1	0.020866
GSK3B	0.020852
NEDD4L	0.020798
LINC01137	0.020766
SOX9	0.020766
ACACB	-0.020761
C3orf14	0.020760
CXCL12	-0.020711
KIAA1549	0.020679
BRIP1	-0.020669
RPAP2	0.020644
SYNPO2	-0.020611
CHEK1	-0.020570
RLN2	-0.020559
LINC01468	-0.020502
TBC1D2	0.020497
TMEM64	-0.020491
CHST14	0.020474
MED13L	-0.020464
CDS2	0.020449
CBFA2T3	-0.020436
NCAPG	-0.020407
HIGD1A	0.020400
TYW5	0.020396
MCM4	-0.020371
ACSS1	0.020358
FOXM1	-0.020357
ENDOD1	-0.020308
AFF3	-0.020269
CARD10	-0.020227
CCNA2	-0.020199
ZNRF1	-0.020171
H19	-0.020159
SLC1A2	-0.020144
NUDT16	0.020137
PLXNC1	-0.020058
MCM4	-0.020043
EGR1	-0.019998
PIK3R2	0.019962
SLC35E2	-0.019935
ZNF506	0.019933
PEX11A	-0.019895
NUDT4	0.019851
TOP2A	-0.019830
CXorf56	0.019828
EGR1	-0.019812
ETV3	0.019781
ZNRF1	-0.019777
SP6	0.019743
LOC389906	0.019737
TFF1	-0.019719
KIF2C	-0.019707
ATL2	0.019554
GLE1	0.019541
MCM10	-0.019537
LXN	-0.019525
SLC26A2	-0.019525
FAM105A	0.019520
GPC6	-0.019426
ASF1B	-0.019412
CA12	-0.019411
TPBG	-0.019347
ADIPOR2	-0.019340
PRKRA	-0.019338
STON2	0.019328
MME	0.019326
SLFN5	-0.019242
CCAR1	-0.019235
ZDHHC21	-0.019214
PRIM1	-0.019193
CCNE2	-0.019185
ITGB5	-0.019180
UBE2C	-0.019171
BOD1	-0.019134
SELM	0.019128
PSCA	0.019127
NRIP1	-0.019098
RAB37	-0.019071
CLMN	0.019048
ZWILCH	-0.019045
ZC3H7B	0.019001
ULK2	-0.018992
CA12	-0.018958
DLG3	0.018927
SLC26A2	-0.018883
RBM15	-0.018832
CA12	-0.018727
SMIM7	-0.018715
SLFN5	-0.018640
GAD1	-0.018635
VTCN1	0.018547
RMI2	-0.018495
C4orf46	-0.018483
CASC5	-0.018458
MCM5	-0.018451
RAB27B	0.018433
ARHGEF28	-0.018420
TGIF1	0.018379
HELLS	-0.018379
BICD1	-0.018361
RAPGEF1	0.018353
CYP4B1	0.018350
MED13L	-0.018347
ZXDC	-0.018317
ZNRF1	-0.018303
CAV2	-0.018267
MCM8	-0.018266
MCM4	-0.018264
CDCA8	-0.018259
SLC4A8	0.018229
ABCG2	0.018211
RAB31	-0.018205
ACTA2	0.018199
TSPAN5	-0.018185
CA12	-0.018137
UPK1A	0.018135
SYNPO2	-0.018129
MBNL1	0.018118
CD47	-0.018099
NRCAM	-0.018096
SPANXC	0.018054
CSTA	0.018036
ARHGAP18	0.018031
XBP1	-0.018019
AKR1C3	-0.018009
MYLIP	0.018008
LOC728061	-0.017987
DCAF8	0.017977
THBS1	-0.017947
MED13L	-0.017943
IRF6	0.017931
WWP2	0.017920
CLUHP3	0.017912
CENPM	-0.017903
TOP2A	-0.017872
TOLLIP-AS1	-0.017812
MTHFD1L	-0.017770
IRS2	-0.017760
CCNA2	-0.017727
POF1B	0.017705
CEP152	-0.017655
SEMA3C	-0.017642
AURKB	0.017619
LIG1	-0.017615
WDHD1	-0.017566
EPB41L2	0.017556
PITPNC1	0.017546
EPS15L1	-0.017545
CENPH	-0.017537
HINT3	0.017520
SNAP23	-0.017483
NRCAM	-0.017452
SLC9A3R1	-0.017435
PRKCA	0.017431
CCND1	-0.017427
TCHH	0.017423
ABCG1	0.017418
PDK4	0.017407
BOD1L1	-0.017385
FANCI	-0.017372
TNFRSF11B	0.017347
PLEKHF1	0.017309
ATM	0.017305
DCAF7	0.017303
DEPDC1	-0.017280
ARHGAP42	-0.017274
PDZK1	-0.017191
BUB1B	-0.017168
KIF18B	-0.017167
RFC3	-0.017156
ZNF224	0.017152
MRPL2	0.017148
DTNA	-0.017147
CDH26	-0.017118
ANK3	0.017081
LOC145474	-0.017049
MED13	-0.017040
MAN1A1	-0.017026
TRPM7	0.017026
DOCK10	0.017021
TSKU	-0.017013
PCSK6	-0.016964
USP25	-0.016956
IFI6	0.016906
C6orf52	0.016904
SORD	0.016896
ERCC6L	-0.016883
UBE2T	-0.016881
RDX	0.016863
DPF3	0.016853
REEP1	-0.016844
RXRA	0.016838
ACER3	-0.016838
GDAP1	-0.016834
E2F8	-0.016824
BUB1	-0.016800
NTRK2	0.016798