!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 4 Hour
!organism	rat
!end_metadata
PDK4	0.350030
MGP	0.280374
TRIM63	0.246158
GLUL	0.224151
ACTN2	0.196413
RHOB	0.184438
ERRFI1	0.137678
TUBA1A	-0.131004
TCAP	0.127728
NDUFS7	0.125262
UCP3	0.118686
XDH	0.116159
ZFP36	0.115589
TSC22D1	0.115522
NR4A1	0.104157
CEBPB	0.103139
PPP2R5A	0.099845
TXNIP	0.099014
KLF9	0.097283
TRIM54	0.091994
NFKBIA	0.090629
DYNLL1	-0.088231
LCN2	0.087269
HSPB6	-0.086815
ATP2A1	0.085988
EIF4EBP1	0.081697
ACTG1	-0.079605
HSP90AB1	-0.074786
RPL28	-0.074064
CRYAB	-0.074038
PDHA1	0.073570
MAP1LC3B	0.073532
SVIL	0.070078
MYL2	-0.067715
MYL12B	-0.066430
COX7B	-0.064363
OAZ1	-0.064065
MAPK14	0.063529
UBC	0.059901
PTP4A1	-0.058743
AQP1	0.058444
CKMT2	0.057615
SGK1	0.057586
HSPA8	-0.057373
MYADM	-0.057102
ATP5B	0.056312
ND5	-0.054901
FTL	-0.054577
SCHIP1	0.054349
CEBPD	0.053957
CHRNA1	-0.053372
PIM3	0.052904
ACADM	0.052438
PPIA	-0.052097
LGALS1	-0.051530
CD63	-0.051147
DNAJB5	0.050849
IFITM3	0.050213
ACTB	-0.050136
ATP5H	-0.049863
ND1	0.049783
GPX1	-0.049567
SPRY1	0.048710
CBFB	-0.048051
LAMC1	0.047561
MDH2	0.046725
CKM	-0.046691
TUBA1B	-0.046367
NDUFA4	-0.045364
EEF1A2	-0.045346
MYH2	0.045322
MPC1	-0.045099
UQCRC2	-0.044923
CTSS	0.044353
SDC4	0.042798
TUBA4A	-0.042700
SEPW1	-0.042039
PECAM1	0.041644
NDUFB10	0.040861
GOT1	0.040542
CA3	0.040085
ATP6	0.039701
GRB10	0.039600
MYL1	0.039583
PKM	0.039343
SLC3A2	0.039266
WIPF3	0.038731
MYLPF	0.038592
RPLP2	-0.038384
TNNC2	0.038358
GSTP1	-0.037878
KLHL41	-0.037698
MYOD1	-0.037640
AMPD1	-0.037633
ANKRD1	-0.037626
RPL22	0.037448
MGST2	0.037277
NDUFV2	0.037191
GOT2	0.036685
EMP1	-0.036637
PSMB5	-0.036573
PSAP	0.036335
YWHAH	0.036314
LDHB	-0.035675
LYZ	0.035406
PCBP4	0.035399
CYC1	-0.034660
ARL4A	0.034285
TNNT3	-0.034172
MYBPH	-0.034120
PSMD2	-0.034101
PSME4	0.033796
TNNI2	0.033770
ASB2	-0.033714
IGF2	-0.033675
ZFAND6	-0.033642
SDHA	0.033466
FTH1	0.033435
MYOG	-0.033388
LYVE1	0.033284
HIGD2A	0.033235
TMA7	-0.033208
PRDX2	-0.033099
MMP14	-0.032676
RPS6	0.032068
TECR	-0.031610
NDUFB8	-0.031485
ATP5C1	0.031392
B2M	0.031323
ATP5A1	0.031204
DBP	-0.030965
JUN	-0.030816
ENO3	-0.030490
NEU2	-0.030378
TUBA1C	0.030286
CACNG1	-0.030029
CCNG1	0.029925
RPL39	-0.029890
PFKM	-0.029731
RPS27L	-0.029680
MAPK6	-0.029630
PYGM	0.029611
AKR1A1	-0.029588
APOE	-0.029107
RPL26	-0.029049
MDH1	0.028855
JUNB	0.028816
ATP1A2	0.028617
CYP27A1	0.028536
ANGPT2	0.028525
RPL37	-0.028426
FAU	-0.028157
SLC25A5	0.028062
RHEB	0.027981
RPL17	0.027798
PAICS	0.027483
COX1	0.027405
PMEPA1	-0.027374
DDX3X	0.027358
RPS17	-0.027074
ATP1B1	-0.026879
NDUFB6	-0.026844
MYH7	0.026718
MYBPC1	0.026379
H2AFZ	-0.026378
DYNLRB1	-0.026075
DUSP1	0.025936
AK1	-0.025585
IDH3G	0.025535
DAB2	0.025328
CXXC5	-0.025170
RPL11	-0.025009
GPX4	-0.024998
BHLHE40	-0.024929
NOL3	-0.024809
ATP1B3	-0.024754
PVALB	0.024511
RPL3L	-0.024478
MYL4	-0.024362
COX4I1	-0.024057
DES	-0.023944
KLHDC3	0.023908
ENO1	0.023848
PPARD	0.023566
CTSV	0.023403
C1QB	0.023344
ND4	-0.023308
CST3	0.023299
ACADL	-0.023292
TCP11L2	0.023221
COX8A	-0.023212
LGALS3	0.023196
CLU	0.023076
POMP	-0.023022
UACA	-0.022987
ANXA5	-0.022941
SOD1	-0.022858
TUFM	0.022642
PTPN3	-0.022546
TPI1	0.022414
PXN	0.022365
YWHAG	-0.022334
CDC42EP3	-0.022247
FLNC	-0.022223
CAPZA2	-0.022176
TUBB	-0.022141
SLC28A2	0.022122
PARK7	-0.022024
PLA1A	0.021947
SIRT2	-0.021852
PPP1CA	-0.021789
NUDT4	-0.021765
UBE2G2	0.021717
NDUFV3	0.021597
MAPK3	-0.021564
NRP1	-0.021523
MGST3	-0.021486
ECE1	0.021338
MYL12A	-0.021264
NDUFC2	0.021231
GNPAT	0.021162
NDUFA5	-0.021097
DECR1	-0.021081
SERPINH1	-0.021064
ANXA2	-0.021032
VIM	-0.020904
BTG1	0.020899
RPL10A	0.020712
MYCBP2	0.020701
LITAF	0.020620
PDLIM1	0.020608
SDCBP	0.020589
TPT1	-0.020510
RRAD	-0.020424
DTD1	-0.020395
MLLT3	-0.020223
ATP6V0C	0.020206
AUH	0.020176
CPA1	-0.020137
RBBP7	-0.020132
PFKFB4	0.020085
NEDD8	-0.020010
TMOD1	-0.019997
PGM2	-0.019974
PABPC4	0.019963
RPL4	-0.019940
NPHP1	0.019935
TOMM20	-0.019922
CD36	0.019900
NEXN	-0.019853
VEZF1	-0.019832
COX6A1	-0.019770
ITM2B	-0.019745
LUM	-0.019733
CYTB	0.019621
RPS7	-0.019610
RPS15	-0.019531
COL5A2	0.019519
AP2M1	-0.019446
PSMD11	0.019385
SERPINE1	0.019322
EGR1	-0.019270
HSPB1	0.019205
H1F0	-0.019185
HADHB	-0.019142
RPS14	0.019025
PDE4A	0.018854
SCN1B	-0.018850
SSR3	0.018781
RPS29	0.018779
NEB	0.018743
LDB3	0.018658
AMD1	0.018599
VEGFA	0.018561
CYCS	-0.018430
MEOX2	-0.018370
PIK3IP1	0.018316
CASQ1	-0.018044
NUCB1	0.017943
P2RY2	-0.017825
PLAGL1	0.017803
RPS9	-0.017590
CAV1	0.017587
GNAS	0.017577
COX7A2	0.017568
RPLP0	0.017568
RPS10	-0.017553
SLC16A3	-0.017523
GNB2L1	-0.017378
TMEM59	-0.017329
CLEC10A	0.017280
KCNC4	-0.017266
UQCRFS1	0.017169
RPL27	-0.017149
TSPAN3	-0.017135
PEBP1	-0.017120
CFB	0.017082
ID3	-0.017029
COX3	-0.016999
PRKAR1A	-0.016943
S100A4	-0.016914
QDPR	-0.016849
CSNK2B	0.016848
MORF4L2	-0.016816
PGAM2	-0.016745
RPL6	0.016716
IRS1	-0.016711
ARNTL	0.016650
TSPO	0.016617
LMNA	-0.016540
SERBP1	-0.016525
GAS6	0.016496
CSRP3	-0.016489
TFRC	-0.016455
CXCL2	0.016423
PSMB2	-0.016410
LDHA	0.016404
SLC25A3	0.016392
MYH1	0.016386
GPD1	-0.016373
PRNP	-0.016355
PTPN1	0.016339
NRARP	-0.016224
ASPH	0.016101
UCP2	0.015951
CSNK1D	0.015943
AHNAK	0.015936
CPT1B	-0.015860
MYBPC2	0.015785
PRDM2	0.015776
DACT2	-0.015750
LOX	0.015750
CAPN3	-0.015704
SLC6A8	-0.015701
SDC2	-0.015613
BIN1	-0.015557
GNG11	-0.015458
CLCN1	-0.015421
CAPG	0.015406
CD81	-0.015401
DCN	0.015389
SLC41A3	0.015356
RPS25	-0.015338
G0S2	-0.015278
MYOC	-0.015209
RAB5B	-0.015196
CPE	0.015171
ANAPC16	0.015146
VDAC1	-0.015138
NDUFB9	-0.015126
TRIM8	-0.015055
PPP2R1A	-0.015011
CD74	-0.014944
ACTA1	-0.014929
CAP2	-0.014892
TIMM17A	-0.014852
HSPB2	-0.014748
HDAC2	-0.014739
CTSH	0.014695
IQSEC1	0.014633
ADM	0.014628
RCHY1	0.014616
FXYD1	-0.014542
DDIT3	-0.014467
ND2	-0.014419
FSTL1	-0.014417
SNN	-0.014396
PGAM1	0.014364
IFRD1	0.014316
GABARAP	-0.014307
SLC37A4	0.014269
HBP1	0.014267
HIBADH	0.014229
KLF4	-0.014206
MYH6	0.014199
RPS11	0.014182
PSMB3	-0.014169
RPS16	-0.014137
RPL7A	-0.014137
SERINC5	0.014130
GFM1	0.014034
IGFBP3	0.013850
NEK7	0.013759
ITGB1	0.013732
ATF3	-0.013721
ATP1B2	-0.013697
NDUFS8	-0.013692
FMO1	0.013690
GRINA	0.013620
CUTA	-0.013615
PGK1	-0.013581
PTTG1IP	0.013566
NDUFA8	0.013563
CLTC	-0.013528
CSRP1	-0.013520
SUCLG1	0.013465
TRAPPC6B	0.013305
RPS8	-0.013253
RPS12	0.013233
DNAJA1	-0.013203
CD14	0.013084
BLVRA	-0.013058
CCND2	-0.013048
NDUFAB1	0.013007
PF4	-0.012969
RAB11FIP5	0.012959
EIF4H	0.012942
PSMD13	-0.012924
FOS	-0.012879
MGLL	-0.012873
AGTPBP1	0.012792
HSF1	-0.012714
FABP6	0.012650
SPP1	0.012603
ARF1	-0.012582
BTG2	0.012581
PSME2	0.012528
CTDSP1	-0.012523
IMP3	0.012520
RUNX1	-0.012487
TST	0.012484
SLC25A20	-0.012477
TOM1L2	0.012386
TIMM23	-0.012354
STAT5B	-0.012346
FKBP1A	-0.012323
PIK3CD	0.012313
H19	0.012299
JUP	-0.012284
SNRPB	-0.012234
BCL2L1	0.012201
GADD45A	0.012148
ACSL1	-0.012144
ATP2A2	0.012143
DAPK2	-0.012136
PSMB4	-0.012037
APRT	-0.012020
PICALM	0.012009
JPH2	-0.012002
TLE1	-0.011995
IMPA1	-0.011932
PRDX1	-0.011926
TJP1	-0.011912
TIMP1	0.011865
POSTN	-0.011857
MAPK12	-0.011842
HMOX1	0.011783
PDLIM4	-0.011774
CYB5R1	-0.011763
SNRNP70	-0.011759
TCEB1	-0.011756
SH2B2	-0.011740
CD38	0.011704
TGFB1	-0.011683
INSIG1	0.011636
ERCC1	0.011632
MAFK	0.011578
FBP2	-0.011577
KTI12	0.011572
SFXN3	-0.011540
COPZ1	0.011511
NR1D2	-0.011502
PLAT	0.011470
NDUFC1	0.011454
PMP22	0.011318
RPS15A	-0.011306
SOD2	0.011285
ATP5F1	-0.011243
MRFAP1	0.011201
ORAI1	-0.011185
NDUFS4	-0.011128
CCDC23	-0.011073
GNB2	-0.011060
ZNRF1	0.011043
AGO2	0.011026
NUTF2	-0.011023
SLC25A17	0.011017
ACTA2	-0.010995
IVD	0.010918
CALR	-0.010858
ID1	-0.010856
MAGT1	0.010851
PSMA6	0.010847
CDK4	-0.010833
EIF5	0.010765
CCNL1	0.010757
SQSTM1	0.010728
EIF2B4	0.010705
NINJ1	-0.010667
TNS1	0.010627
PSMC2	-0.010618
SYNJ2	0.010611
DNM1	-0.010610
CRISPLD2	0.010550
GRN	-0.010547
GNAI2	0.010543
DBN1	-0.010455
PPIF	-0.010420
TXNL1	-0.010419
ETFDH	-0.010346