!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Halothane
!smiles	C(C(F)(F)F)(Cl)Br
!drugbank_id	DB01159
!pubchem_cid	3562
!cell_type	Whole brain - 10 exposures
!organism	rat
!end_metadata
TTR	0.246666
PRNP	0.184277
SPARCL1	0.161896
PABPC4	-0.161312
RPS29	0.161171
NDRG4	-0.155433
MBP	-0.153384
LDHA	-0.125045
RPL19	0.123389
RPL9	0.123062
HSPA8	0.121673
COX3	-0.112622
ATP6V0C	-0.109974
TPI1	-0.103022
TPT1	0.100720
CYTB	-0.099360
ACTB	-0.097279
COX1	-0.094178
GABRA6	0.092626
CST3	0.092060
RPL26	0.091304
RPL17	0.091081
NDRG2	0.089444
TUBA1B	-0.086429
RPL24	0.085383
RPS26	0.084987
SLC25A5	0.082652
TUBA1A	-0.082373
MPC1	0.081138
ATP6	0.080713
ALDOA	-0.080498
CALB1	0.080149
COX7A2	0.079768
ATP1A3	-0.079068
RPL31	0.078825
DNM1	-0.077803
PKM	-0.077698
EIF4A2	0.076930
ND2	0.076848
ENO1	-0.074398
RTN1	0.073883
RPS15A	0.073743
NDUFA4	0.071043
NCKAP1	0.070512
PVALB	0.070211
TUBB	-0.070151
FTH1	0.070013
NNAT	-0.068864
RPL15	0.067748
SLC25A3	0.065647
RPS27A	0.064274
BASP1	-0.063784
COX4I1	0.063432
RPL12	0.062984
NELL2	0.062973
ND5	0.062649
CAPNS1	-0.062513
MRFAP1	-0.062083
ALDOC	0.061907
ENO2	-0.060074
GLUL	0.059503
UCHL1	-0.059485
PGK1	-0.059291
GABARAPL2	0.059184
MOBP	-0.058612
ACTG1	0.058601
CTXN1	-0.058550
RPS23	0.058270
CHN1	-0.058152
ND4	0.057959
ATP5O	0.057124
PCP4	0.057114
RPS12	0.056313
CTSS	0.056220
NDUFC2	0.056073
PMEPA1	-0.056050
VAMP2	-0.055800
GPX4	-0.054928
YWHAH	-0.054001
SPARC	0.052417
RPS21	0.052382
CNP	-0.052096
RPL37	0.050592
RPS4Y1	0.050243
VGF	-0.050026
APOE	-0.049828
RPS25	0.049404
RPL27A	0.049013
GAPDH	-0.048734
ENPP2	0.048520
HSP90AB1	0.048282
RPS11	0.047571
RPL5	0.047454
CACNA2D1	0.046943
CCNG1	-0.046903
MAP1LC3A	-0.046507
RPS6	0.044309
VSNL1	0.043949
CAPZA2	0.043786
SNAP25	0.043505
GDI1	0.043142
CAMK2B	0.042903
CSPG5	-0.042814
CLU	-0.042651
RPS17	0.042600
RPS5	0.042283
PLP1	-0.042105
ATP5C1	0.042066
GSTM5	0.041706
PITPNA	0.041497
SLC4A4	0.041284
CKB	-0.040974
CLTA	0.040938
TMEM59	0.040853
CYC1	0.040769
RPL18	0.040722
CYCS	0.039725
NDUFB9	0.039312
DDN	-0.039178
EGR1	-0.038729
HMGCS1	-0.038696
SPOCK2	-0.038499
ATP5F1	0.038493
RPS14	0.038413
UQCRC2	0.038372
ATP5A1	0.038342
SST	-0.038290
CPE	0.038260
RELN	0.038212
NEUROD1	0.038212
ST3GAL5	-0.038043
FKBP1A	0.037830
RPL10A	0.037679
RPL13A	0.037296
ARF1	-0.037234
CD63	0.036855
SNRNP70	-0.036795
RPS7	0.036566
IDH3G	0.036457
ATP5B	0.036347
TECR	0.036257
COX7B	0.036130
SYP	-0.036036
CD81	0.035995
RPL4	0.035188
ATP6V1F	0.035053
BIN1	-0.034776
ID2	0.034697
PAICS	0.034472
ARC	-0.034431
OAZ1	0.034015
SDCBP	0.033955
PSMC5	0.033827
LPHN1	-0.033611
RAB3A	-0.033328
RPS8	0.033260
PTOV1	-0.033091
COLQ	-0.033087
RPL18A	0.032916
CAMK2N1	-0.032652
UBE2J2	-0.032601
ATP5H	0.032510
RPS16	0.032139
SLC25A11	0.032097
RPS13	0.031997
PRKAR1B	-0.031797
GAP43	-0.031374
TUBA4A	-0.031315
RPS3	0.031308
STX1B	-0.031264
RPSA	0.031027
KCNC1	0.030618
ATP9B	-0.030534
CCK	-0.030480
RPL35	0.030268
RPS15	0.029871
SLC6A1	0.029781
CHN2	0.029415
RNF4	0.028963
GPD1	0.028831
S100B	0.028538
CX3CL1	-0.028411
SLC12A5	0.028358
COX8A	-0.028319
SV2B	0.028211
FASN	-0.028109
CDC37	-0.028023
TMEM55B	-0.027816
MDH2	0.027776
PPP1CA	0.027569
NDUFB6	0.027369
TMEM47	0.027210
IQSEC1	-0.027187
MDH1	-0.027086
GABRA1	0.027015
GUCY1B3	0.027005
YWHAG	0.026801
SEPP1	0.026676
RPL3	0.026663
GLS	0.026631
FAM160B1	-0.026534
INSIG1	-0.026456
DBP	0.026395
CFL1	0.026378
RPS10	0.026378
GFAP	-0.026261
GSTM2	-0.026188
HSD11B1	0.026140
BTG1	0.026039
GABRG2	0.025996
ATP5G1	0.025826
RPS9	0.025664
YWHAB	0.025494
COX7A2L	0.025270
SLC6A15	0.025067
RPL6	-0.025016
B2M	0.025007
INF2	-0.025000
SLC3A1	-0.024970
GNAI2	-0.024787
ZNF580	-0.024707
TCEB1	0.024685
LDHB	0.024675
TAGLN3	0.024610
MAPK8IP2	0.024575
DYNLRB1	-0.024375
STX1A	-0.024042
GABRB2	0.024005
MFGE8	-0.023811
PPP3R1	0.023765
SCN1B	-0.023708
GDA	-0.023688
INPP4A	0.023370
SDHA	0.023311
CSRP1	-0.023225
ATP5D	0.023180
APEX1	0.023118
HYAL2	-0.022863
HAGH	-0.022721
PPT2	-0.022477
WBP4	-0.022358
PPP2CA	0.022334
RPL23	0.022314
NPY	-0.022305
UNC5B	-0.022166
LAMP1	-0.022038
BAG6	0.022025
COPZ1	-0.022004
MATK	-0.021959
DNPEP	-0.021958
CPLX1	0.021872
ITPR1	0.021854
COX5A	0.021687
NR4A1	-0.021673
RPL30	0.021602
ATP2A3	0.021590
TNKS2	0.021529
UQCR11	0.021485
RPL8	0.021442
HMGCS2	0.021257
SCN1A	0.021028
GRIN2C	-0.020999
SLC14A2	-0.020982
PRKAG1	-0.020927
ACAA2	0.020904
MBOAT7	-0.020871
PRKAR1A	0.020847
RASA2	-0.020751
VPS4A	-0.020712
NDRG3	-0.020660
ITIH3	-0.020610
SCAMP1	0.020544
NGFR	-0.020443
CTBP1	-0.020397
TSPAN17	-0.020372
RALGDS	-0.020345
PTPRS	-0.020343
AQP4	0.020317
MSMO1	-0.020297
TESC	0.020293
PPP2CB	0.020252
YBX1	0.020125
MVD	-0.020084
ALAS2	-0.020039
NDUFA5	0.019984
DNAJA2	0.019912
GAA	-0.019883
PRKCB	0.019822
BTF3L4	0.019745
H2AFZ	0.019506
PSMB4	0.019352
ACAT2	-0.019294
GDI2	0.019284
PTPRJ	-0.019147
GOT1	-0.019023
NEFL	-0.018965
STARD3	-0.018959
MGST3	-0.018927
KLK6	-0.018871
HSPD1	0.018844
VPS29	0.018829
EEF2	0.018717
DCTN1	-0.018638
ACOT7	-0.018609
CXXC5	-0.018357
TSPAN3	-0.018344
MAP1A	-0.018325
CELSR2	-0.018325
TCF4	0.018260
RABAC1	0.018234
ARPC4	-0.018214
MARC2	-0.018192
RPLP0	-0.018165
NDUFB2	0.018152
PPT1	0.018106
MIF	-0.017949
NDUFB8	0.017913
VIM	-0.017860
AURKAIP1	0.017850
AZIN1	0.017791
NR1D2	0.017786
GABRD	0.017720
LIN7B	-0.017710
FABP5	-0.017692
NDUFAB1	0.017668
ARFGAP2	-0.017667
YWHAZ	-0.017650
BNIP3L	0.017567
B3GAT1	-0.017551
NTM	0.017545
CELA2A	-0.017515
BAX	-0.017493
PEBP1	0.017477
CXCR1	-0.017440
RABGGTB	0.017417
MAP2K6	-0.017408
PJA2	0.017401
RASGRF1	-0.017190
EEF1A2	-0.017164
ARF5	-0.017143
SHC3	-0.017044
DOCK9	0.017037
HNRNPAB	0.017007
PLS3	0.016942
NAPA	-0.016918
DBN1	-0.016834
IL33	0.016831
LEP	-0.016745
RAB5B	0.016685
PSMA2	0.016621
PFKFB4	-0.016583
PSAP	-0.016540
BLVRA	-0.016527
GSTP1	0.016526
PCBP4	-0.016524
KLC1	-0.016513
EXOC6	-0.016457
MAP1LC3B	0.016418
FXYD1	0.016278
SUB1	0.016256
PMCH	0.016213
ITPKA	-0.016119
GATM	0.016094
PADI2	-0.016021
GRIK5	-0.016012
TMEM255B	-0.016008
NDUFC1	0.015991
ARF4	0.015990
C11orf73	0.015985
STRN4	-0.015984
GPR176	-0.015984
ECHS1	-0.015963
TNFRSF1A	-0.015952
PRKACB	0.015919
VMP1	0.015915
HIBADH	0.015904
NUDT4	0.015881
GAD1	0.015879
PENK	0.015875
MOG	-0.015830
LCK	-0.015813
RRAGA	0.015789
PSMB1	0.015697
YWHAE	0.015576
SKIV2L	-0.015576
RPL14	0.015562
RPL7A	-0.015552
BCAN	-0.015488
ATP6V1A	0.015452
UBE2B	0.015405
RAF1	0.015383
CRYAB	0.015347
VPS45	-0.015341
ADCY3	-0.015327
MTOR	-0.015299
SLC2A1	0.015248
HPCA	-0.015237
CPLX2	0.015232
PTCH1	-0.015232
SREBF1	-0.015218
GPX1	0.015216
ATN1	-0.015172
C17orf103	0.015149
GRN	-0.015111
SYNJ2	-0.015111
RAB6A	-0.015007
PPP1R9B	-0.014947
SPTLC1	-0.014943
RPL36AL	0.014938
NDUFA9	-0.014926
SPOP	-0.014903
ARHGEF9	0.014857
APOD	-0.014831
SVOP	-0.014799
SCG5	0.014784
PRKACA	0.014758
CHRM3	-0.014755
TUBB4B	-0.014752
PSMD11	0.014736
DHX9	0.014728
LYZ	-0.014725
EEF1G	0.014714
CORO1B	-0.014649
GSTA5	0.014633
DLK1	-0.014627
ZFAND6	0.014604
NDUFA8	0.014595
RAB11FIP5	-0.014592
BSG	-0.014557
HADHA	-0.014545
GSTO1	0.014530
VPS52	0.014522
CNIH2	-0.014516
PFKP	0.014489
DYNC1H1	-0.014482
PPIA	0.014473
POMP	0.014443
SMIM5	-0.014421
GNB2	-0.014384
TRAPPC10	-0.014384
PSMD1	0.014362
NPHP1	0.014338
CACNB3	-0.014323
PHLDB1	-0.014312
SERBP1	0.014305
KCND2	0.014282
MPRIP	0.014249
NCAPH2	-0.014228
SPTAN1	0.014220
FABP6	-0.014216
GABBR1	0.014161
CNR1	0.014123
LSAMP	0.014123
CHGA	-0.014117
TTC3	0.014107
SLC32A1	-0.014089
NRN1	-0.014075
SYN1	0.014047
CFTR	-0.014044
THRA	-0.014039
SOD1	-0.014029
PRDX6	0.014023
ATP6V1B2	0.013999
DPYSL4	0.013998
FABP3	-0.013961
CDC42BPB	-0.013931
ALPL	-0.013907
PDCD10	0.013844
CAP2	0.013809
PAIP1	0.013801
DPP6	0.013699
GNG10	0.013693
SPTBN2	-0.013636
CALB2	-0.013603
CPSF4	-0.013601
MGST2	-0.013585
AGTPBP1	0.013575
GRIP2	-0.013542
KCTD15	-0.013505
INA	0.013437
GJB1	-0.013437
OAS1	-0.013411
FDXR	-0.013401
PTN	-0.013395
CYP51A1	-0.013359
NRCAM	0.013357
CREG1	-0.013340
GSK3A	-0.013319
AP1S1	-0.013316
UBXN1	-0.013315
TOMM6	-0.013220
NFKB1	0.013204
NSG1	0.013203
PPP2R2B	0.013147
ATPIF1	0.013146
ND1	0.013101
SLC1A6	0.013085
DLG4	0.013072
SLC4A3	-0.013050
ACP2	-0.012963