!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 45 minutes
!organism	rat
!end_metadata
SLC25A4	0.176331
PYGM	0.163835
CRYAB	-0.155713
HSPB6	-0.155301
RHOB	0.147830
TCAP	-0.141761
PVALB	0.137102
NFKBIA	0.132540
TPI1	0.126705
MYL2	-0.123292
LDHB	-0.115505
ITGB1	-0.115361
ACTG1	-0.107843
MYL12B	-0.106835
MYLPF	-0.106638
MYBPC1	0.105143
MYL1	0.104770
COL3A1	0.100841
NDUFC2	-0.098456
DYNLL1	-0.097331
MDH2	0.097038
NDUFV2	0.093664
ACADM	0.093505
GNB2L1	-0.093396
RPL37	-0.093126
ATP5B	0.089471
ZFP36	0.088291
LDHA	0.087134
CASQ1	-0.087008
UBC	-0.086462
NDUFS7	0.085672
HSPA8	-0.083866
FTL	-0.083758
IDH2	-0.081795
HSPB1	-0.081375
COX5A	0.080441
RPL17	0.080270
CHRNA1	-0.074516
UCP3	0.073325
H19	0.072703
TNNI1	-0.072628
CSRP3	-0.072431
RPL10	-0.071425
MYH7	-0.070478
GOT1	-0.070412
NDUFB9	0.070167
PTP4A2	0.069318
MGP	0.069247
TPT1	-0.067976
CD63	-0.067234
MYH1	0.065868
LGALS1	-0.065548
FLNC	-0.065028
RPL39	-0.064040
PSMD2	-0.062909
FLOT1	0.062868
RPL18A	-0.062230
ALDH1A1	0.061108
NDUFA5	0.060958
ANKRD1	-0.060712
RPS9	-0.060481
RPS8	-0.059930
ATP5F1	-0.059802
GAA	-0.059543
LDB3	-0.059265
ERRFI1	0.058701
POSTN	-0.058171
KLF9	0.057994
PPP2R5A	0.057245
MDH1	0.057192
TUBA1B	-0.057034
RPL19	-0.056165
COL1A2	-0.055791
ACTC1	-0.055060
RPL9	0.055044
THBS4	-0.055036
ATP6	0.055001
RPL22	-0.054821
HADHB	-0.054753
GAPDH	0.054540
RPS17	-0.054536
ACTN2	0.054300
RPS10	-0.054019
RPS15A	-0.053930
MYH2	-0.053457
ASB2	0.053414
TUBA4A	-0.053295
CTSV	-0.052297
TNNC2	0.052182
RPS21	-0.050903
SLC37A4	0.050890
MYLK2	0.050718
CNBP	0.050694
G0S2	-0.050652
TRIM54	-0.050370
SQSTM1	0.050316
ZFP36L1	-0.050065
SMPX	-0.050014
ATP1B1	-0.049711
RPL26	-0.048924
PDK4	0.048768
COX3	0.048691
SLC41A3	0.048676
CCNG1	0.048392
GPX1	-0.048142
NDUFB2	0.047901
SDHA	-0.047773
SNRPB	-0.047442
NAPA	0.047272
SLC25A3	-0.046956
TIMM23	-0.046730
AMPD1	0.046705
IGF2	0.046548
ND1	0.046373
ND5	-0.046301
TIMM17A	-0.046211
RPL3L	-0.046077
GNAS	0.045945
CEBPB	0.045895
RPLP2	0.044848
RPL31	0.044569
PKM	0.044399
LUM	-0.044334
MORF4L2	-0.043514
MYL4	-0.043430
ACADL	-0.042938
NEB	0.042193
EEF1G	-0.041870
FTH1	0.041787
PSME1	0.041700
CACNA2D1	-0.041674
NDUFC1	-0.041023
PSME4	-0.040973
TNNI2	-0.040257
ID3	-0.040252
EGR1	-0.040045
AHNAK	-0.040030
PSMD11	-0.039852
ATP5J	-0.039847
OAZ1	0.039722
PTGIR	0.039464
NR4A1	0.039290
ACTA1	-0.039254
NDUFB3	-0.039099
RPL8	-0.039064
COX4I1	-0.038551
TMEM59	-0.038360
TNNT3	-0.038160
ARF1	-0.037789
TCP11L2	-0.037658
MYBPC2	0.037600
SCN1B	0.037225
RPL12	-0.037048
SIRT2	-0.036900
PFKM	0.036836
RPS13	-0.036778
KLHL41	-0.036589
NDUFA8	0.036495
ACTA2	0.036465
NDUFB4	0.036099
PHKG1	0.036041
RPSA	-0.036039
RPL13A	-0.035515
H1F0	-0.035240
NEU2	-0.035117
MGST3	-0.034963
PPIA	-0.034872
RPL18	-0.034146
DBP	-0.034088
GNG5	-0.033821
GPD1	0.033328
NDUFA3	-0.033194
ARL4A	0.033064
APOE	-0.032955
COX2	0.032724
RPS29	0.032290
MMP14	-0.032287
ATP5D	-0.032222
MYADM	-0.032150
CAV1	0.031677
ATP2A1	0.031595
FABP6	0.031509
ACAA2	-0.031478
CTSB	-0.031280
FXYD1	-0.031208
CTSD	-0.031153
CPT1B	-0.031152
ND2	0.031120
NDUFB6	0.031019
PPP1CB	0.030740
GPX3	-0.030660
TXNIP	0.030603
RXRG	0.030349
CITED2	-0.030041
BTG1	-0.029798
APH1A	-0.029352
COLQ	0.029037
JPH2	0.029014
RPL28	-0.028940
ATP5H	0.028856
DLAT	0.028764
FABP3	-0.028757
DCN	-0.028630
PRKAR1A	-0.028536
TRIM63	0.028484
TUBA1A	-0.028317
NAA15	-0.028310
GAS6	0.028308
CTBP1	0.028273
RPL11	0.028234
CD151	-0.028210
SDHAF2	-0.028140
HIBADH	-0.028128
NUDT4	-0.028098
ENO1	-0.027870
CDC42EP3	0.027756
NR1D1	-0.027745
COX6A1	-0.027678
NOL3	-0.027480
UACA	-0.027269
PTP4A1	-0.027253
NDUFA4	-0.027112
TSPAN3	-0.027078
JUN	-0.027037
CAPZA2	-0.027033
NDUFV3	0.026918
DYNLRB1	0.026829
NEK7	0.026391
ATP2A2	-0.026346
CBX1	0.026343
MFGE8	-0.026328
PDYN	0.026296
ACTB	-0.025822
ATP6AP1	-0.025788
LYZ	-0.025684
SGK1	0.025373
RPS14	0.025353
ACKR3	0.025301
NRARP	-0.025136
ATP6V1F	-0.025120
PSMB4	0.024892
RPLP0	-0.024862
ECHS1	-0.024690
AP2M1	-0.024479
LAMTOR1	-0.024467
CKM	-0.024403
APP	0.024382
ATP5A1	-0.024343
NDRG2	-0.024323
RPL6	-0.024283
DNAJA1	-0.024272
YBX1	0.024213
KCNC4	0.023925
ADM	0.023906
ORAI1	-0.023801
HSPD1	-0.023630
PNRC2	-0.023506
ACSL6	0.023338
AES	0.023252
BECN1	-0.023233
ATP1A2	0.023206
EIF4A2	-0.022997
RPL35	-0.022952
MYF6	-0.022912
COL1A1	-0.022880
FOS	-0.022751
AKR1A1	0.022717
PAICS	0.022632
SPARC	-0.022503
PSMC4	-0.022476
SLC16A1	-0.022464
PSMC3	-0.022454
GLUL	0.022226
PABPC4	0.022223
METAP2	0.022006
PSMC2	-0.021970
CYC1	-0.021928
EIF4EBP1	0.021899
B4GALT6	0.021879
RPL5	-0.021826
PSME2	0.021813
RPL15	0.021769
SEPW1	0.021685
ATP1B2	0.021659
VCP	-0.021559
MAP2K2	0.021556
ACSL1	-0.021455
NSFL1C	-0.021423
CS	-0.021167
MAPKAPK3	0.021029
CPT2	-0.020954
CBFB	0.020858
YBX3	0.020690
NPHP1	0.020515
ATP9B	-0.020449
ACADVL	-0.020439
DDIT3	-0.020326
GPC1	-0.020306
TFRC	-0.020296
ATP5C1	-0.020285
MGST2	0.020269
MPC1	0.020250
GAMT	0.020146
PTOV1	0.020098
CACNA1S	0.020082
PCBP4	0.019858
PPP2R1A	-0.019817
B2M	-0.019624
KCNA5	0.019601
PRKCG	0.019586
CYCS	0.019581
TOMM6	-0.019356
NDUFB8	0.019138
TSC22D1	0.019124
TAF6	0.019094
NDUFS1	0.019052
MYOG	-0.018917
KLF10	-0.018893
NR1D2	-0.018891
TXNRD1	-0.018822
ATP6V0C	-0.018798
PSMC5	-0.018776
PTPN3	-0.018703
RUNX1	-0.018675
CEBPD	0.018637
HES1	-0.018568
DNAJB9	-0.018478
RPL23	0.018464
ANXA6	-0.018438
ATP5G1	0.018338
SEPP1	0.018306
GMPR	0.018263
RPS6	-0.018252
COL5A2	-0.018131
SLC6A8	0.018114
CST3	0.018023
SPARCL1	0.018006
PPM1A	0.018005
PDK2	-0.017968
COX7A2	0.017854
COX7B	0.017735
JUP	0.017724
YWHAH	-0.017686
CSNK1D	0.017569
F2R	-0.017544
TCEB1	-0.017475
ARC	0.017405
APRT	-0.017337
CD74	-0.017335
PPP3CA	0.017274
CAP2	-0.017263
YWHAZ	-0.017171
PXN	0.017148
EFNA1	-0.017119
RPS3	0.017084
ME1	0.017083
BCKDHA	-0.017043
ACO1	-0.016867
PADI2	0.016792
TRIM8	-0.016752
HRAS	0.016703
PDP1	0.016689
IGFBP6	0.016655
BLVRA	0.016549
FAU	-0.016515
VEGFB	0.016507
EDF1	-0.016414
SFRP4	0.016413
EGFL7	-0.016335
STAT5B	-0.016192
PMP22	0.016166
BNIP3L	-0.016153
SCD	-0.016095
PRKCDBP	0.016091
GRN	-0.015952
MYL9	0.015901
DACT2	-0.015884
TEF	0.015838
FURIN	-0.015829
ANXA4	-0.015803
MYH8	-0.015777
COX6A2	0.015738
GNG11	0.015720
HPCA	0.015636
PSMC1	-0.015613
VIM	-0.015544
UQCRFS1	0.015532
RPL27	-0.015459
VEGFA	0.015447
SOD1	0.015374
IFITM3	-0.015321
SLC16A3	0.015299
IRF1	-0.015289
RPL36AL	-0.015178
TOMM20	-0.015171
EIF4E2	-0.015141
BTG2	-0.015109
SNN	-0.015098
KARS	-0.015093
PGAM2	0.015088
CD1D	0.015085
EIF2S3	-0.015054
COX8A	-0.015042
CLTA	0.015024
LPHN1	0.015015
P4HA1	-0.015003
LOXL1	-0.014894
ALPL	0.014891
YWHAE	0.014864
TNFRSF21	-0.014859
CXCL14	-0.014856
SLC29A1	-0.014812
DES	-0.014771
BHLHE40	-0.014699
NGFR	0.014690
VDAC1	0.014677
HIGD2A	-0.014670
CSTB	0.014649
RPS4Y1	-0.014623
PEBP1	-0.014622
NACA	-0.014607
PRMT1	-0.014571
ANXA2	0.014567
RPL30	0.014564
PRKAA2	0.014559
GSK3A	0.014494
JTB	0.014351
SPRY1	0.014322
CD36	0.014291
TCTA	-0.014285
RPL3	-0.014276
LYVE1	0.014256
ZFAND6	-0.014192
MEF2D	0.014145
CXCR1	0.014105
RPL24	-0.014050
NUCB1	-0.014029
TMA7	0.013975
MSTN	0.013974
CLTC	-0.013868
S100A4	-0.013862
DLST	0.013811
TXN2	-0.013770
GABARAP	-0.013740
ECH1	-0.013728
PRKAG1	0.013726
ADRB2	0.013718
CSDE1	0.013694
MARC2	0.013684
RPL14	-0.013646
GRB10	-0.013640
CCT3	-0.013631
ALAS1	-0.013620
TSPAN8	-0.013602
PDHA1	0.013601
SCARB1	-0.013601
MC3R	0.013587
MAPK14	0.013579
MYH6	-0.013489
RHOC	-0.013488
NCL	-0.013465
NFIB	0.013462
TXNL1	-0.013366
KAT5	0.013342
CPSF4	0.013293
HSD11B1	-0.013275
PRKACA	0.013271
TUBB	-0.013261
ARF6	-0.013254
PSMD13	-0.013253
KTI12	0.013249
PNRC1	-0.013238
CAT	0.013202
EEF1A2	-0.013183
IGFBP5	0.013178
FOXS1	-0.013176
TULP1	0.013151
PPP1CA	-0.013119
HSPA9	-0.013094
NDUFS8	-0.013083
VMP1	-0.013056
PLOD1	-0.013053
RARA	0.013037
RPS23	-0.013030
APEX1	0.013025
CHURC1	-0.012963
ANAPC5	-0.012929
PDE4B	-0.012917
SPRR1A	0.012909
UBQLN1	-0.012853
RPL7A	-0.012822
ARF4	-0.012799
RGCC	0.012793
UNC5B	0.012722
CHORDC1	-0.012720
CLUH	-0.012714
GINM1	-0.012698
GDI2	-0.012687
SOD2	0.012672
CLCN1	-0.012645