!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 18 Hour
!organism	rat
!end_metadata
UBC	0.220697
GLUL	0.217372
HSPB1	0.176183
TCAP	-0.175045
RRAD	0.160046
COL1A2	-0.153199
COL3A1	-0.148357
ACTG1	-0.147607
CST3	0.143831
AK1	-0.138422
MYL2	-0.131162
ACTB	-0.123604
TUBA1B	-0.117102
EIF4A2	0.115020
ACTN2	0.111691
GPX3	0.105940
ATP2A1	0.105148
COL1A1	-0.101177
PSMD11	0.098892
HSPA8	0.094819
PYGM	0.093355
FLNC	0.090611
CSRP3	0.087567
MYBPC1	0.087081
TUBA1A	-0.086375
ENO3	-0.084557
TRIM54	0.084381
TSC22D1	0.083777
LYZ	0.082695
JPH2	-0.080388
HADHB	0.076595
CKM	0.076546
TUBA4A	-0.075658
AMPD1	-0.074818
MYL12B	-0.073417
ALDH1A1	0.073229
COX5A	0.073211
ASB2	-0.073085
ANKRD1	0.072743
NDUFC2	-0.071660
FXYD1	-0.071655
ACADL	0.071152
SLC37A4	-0.070712
RPS21	0.068962
MAP1LC3B	0.067837
LUM	-0.066942
CD36	0.066646
EIF4EBP1	0.065643
CACNG1	-0.064543
NEU2	-0.064134
SPARC	-0.063906
NDUFB6	-0.063014
UQCRC2	-0.062781
SVIL	0.062567
PVALB	-0.062193
PFKM	-0.062157
CBFB	0.061605
COX2	0.061467
NDUFB3	-0.060488
ACAA2	0.060075
GPD1	-0.059479
DES	0.058718
G0S2	0.058618
YWHAH	0.058173
H19	-0.057932
MYBPH	-0.057895
COX7B	-0.056391
CTSV	0.055751
MPC1	-0.054857
NDRG2	0.053179
RPS27L	-0.052884
ND4	-0.052858
CACNA2D1	-0.052388
ATP6	-0.052218
LDHA	-0.051502
EEF1G	-0.051354
CKMT2	0.051315
RPL15	0.051219
NPHP1	-0.050753
PPIA	-0.050719
TIMP2	0.050672
ACADM	0.050387
RPL17	0.050226
ENO1	-0.049875
MDH2	0.048905
CCNG1	0.048747
ECH1	0.048670
SLC25A4	-0.047562
LPL	0.047504
RPL27A	-0.047448
RPS14	0.047087
HADHA	0.046247
B2M	-0.046231
TNNI2	-0.045992
DYNLL1	-0.045651
SCHIP1	0.045648
TXNIP	0.045577
DCN	-0.045566
NR1D2	-0.045026
GRINA	0.044740
UCP3	-0.044367
GOT1	0.044237
RPL39	-0.043758
PHKG1	-0.043719
PSMC4	0.043646
APOE	0.043515
HSP90AB1	0.043331
UCP2	0.043309
EIF2B4	0.043045
ND2	-0.042623
PGK1	-0.042063
NDUFB8	-0.041844
IGFBP6	0.041659
SNRPB	-0.041518
H2AFZ	-0.041457
CHRNA1	-0.041289
PSMB2	0.041085
NR4A1	-0.040758
HSP90AA1	0.040757
PSAP	0.040435
PSMB4	0.040276
FSTL1	-0.040216
PSME4	0.039606
CACNA1S	-0.039599
RPL10A	-0.039479
NSFL1C	0.039351
PCOLCE	-0.039130
NDUFC1	-0.039082
KLHDC3	0.039003
GSTM1	0.038567
NOL3	0.038480
KCNJ11	-0.038121
RPL18A	0.038115
HSPB6	-0.038070
RPS17	-0.037500
NR1D1	-0.037205
OAZ1	-0.037182
MRFAP1	-0.036676
AQP1	-0.036613
CA3	0.036376
NDUFB4	0.036369
ACTC1	-0.036143
PSMD1	0.035813
TPT1	-0.035753
MYH7	0.035638
TNNI1	-0.035629
RPL23	0.035627
ATP5J	0.035268
RPLP0	0.035230
MYBPC2	0.035186
SLC25A3	-0.034984
NDUFS7	0.034921
ATP5G1	-0.034797
CAPZA2	-0.034706
SLC3A2	0.034493
HDLBP	0.034226
GAA	0.033648
PSMC2	0.033589
GABARAP	0.033466
PPP2CA	0.033432
SPARCL1	-0.033333
GPX1	-0.033245
IGF2	0.032906
CHRNB1	-0.032828
SIRT2	0.032528
RPL3L	-0.032519
PSMD2	0.032405
MGST3	-0.032148
MAPK14	0.031713
DDX3X	0.031566
MYF6	0.031528
COL15A1	-0.031374
PABPC4	-0.031330
RHEB	0.030949
TECR	-0.030911
CPT2	0.030801
CTBP1	0.030484
CAPNS1	0.030473
P4HA1	-0.030420
VCP	0.030385
SLC6A8	0.030340
PPP1CB	0.030172
CYC1	-0.030121
UBE2J2	0.030087
LOX	0.030041
ATP5A1	-0.029958
CAV3	-0.029856
PSMC1	0.029842
TIMM17A	-0.029712
PDLIM1	-0.029695
PTP4A1	0.029689
THBS4	0.029434
SLC2A4	0.029349
PSMA7	0.029308
TUBB	-0.029142
CTSS	0.029074
RPL4	-0.028817
RPS11	0.028812
NDUFV2	0.028746
CD74	-0.028724
COX4I1	-0.028645
SERPINH1	-0.028367
NDUFA5	0.028195
MAPK6	-0.028174
RPS8	-0.028174
PSMD4	0.028132
PTP4A2	-0.028107
RPL35	0.027980
MMP14	0.027960
SHFM1	-0.027909
DNAJA4	-0.027744
MAP2K6	-0.027658
DHRS7C	-0.027519
TXN2	0.027247
DBP	-0.027108
MAP1LC3A	0.027070
PPP3R1	-0.026929
PDHB	-0.026843
BSG	0.026750
SOD1	0.026686
RPSA	-0.026584
PSMB1	0.026187
MYLK2	-0.025678
FTL	-0.025658
PDK4	-0.025646
MYL1	-0.025618
PCBP4	0.025605
TNFRSF21	-0.025555
RABAC1	0.025431
KCNC4	-0.025306
PFN1	-0.024963
ITGB1	0.024924
PSMA6	0.024784
TCEB1	-0.024712
PPIF	-0.024631
PHKA1	-0.024605
ARNTL	0.024522
ORAI1	0.024499
UBR5	0.024302
EEF1A2	0.024109
CYP27A1	0.024054
TOM1L2	0.023926
HIGD1A	-0.023756
TMED10	0.023697
SPP1	0.023429
HGS	0.023406
DYNLRB1	0.023401
PPP2R5A	0.023198
PEBP1	-0.023127
ACSL6	-0.023106
DNAJA2	0.023013
DCAF6	0.022888
CLU	-0.022791
ATP5H	0.022759
NDUFB2	0.022559
COX6A2	0.022538
RRAGA	0.022524
COX7A2	-0.022486
PRDX2	0.022087
PHB2	0.022034
COA5	-0.021983
CLTC	-0.021934
COX1	-0.021792
HP	0.021735
PSMA1	0.021707
OAT	0.021689
CPE	-0.021682
RPL7A	0.021660
CXCL14	-0.021660
DNAJB5	0.021655
SEC61B	-0.021597
ATP1B3	-0.021554
SNRNP70	0.021425
CASQ1	0.021305
PSMB3	0.021254
ATP6V0C	0.021154
SNRPN	-0.021007
NDUFB9	-0.020969
MYLPF	0.020944
DLST	-0.020804
CPT1B	0.020792
TMBIM6	-0.020708
NDUFA3	0.020535
TNNT3	-0.020465
TMEM59	-0.020266
PSMC5	0.020210
PPP3CA	-0.020192
NUDT4	-0.020179
H1F0	-0.020166
MYL4	-0.020094
COX6A1	-0.020000
RPLP2	0.019850
USE1	0.019812
CAPN2	0.019796
ANXA6	-0.019732
CYCS	-0.019662
ZFAND6	-0.019633
IPO7	0.019582
MYL9	-0.019534
CLCN1	-0.019512
ATP5F1	-0.019502
CITED2	-0.019378
NACA	0.019354
COX3	-0.019302
DAB2	-0.019266
ARF1	-0.019230
GINM1	0.019189
PPP1CA	-0.019112
SCN1B	-0.019065
ATP5C1	-0.018936
NDUFA9	0.018808
VEZF1	-0.018799
HUWE1	0.018771
TCP11L2	-0.018751
GSTM2	0.018680
GPC1	-0.018665
PSMA5	0.018647
IL15	0.018630
HSPD1	-0.018606
HIGD2A	0.018507
ALDOA	-0.018496
NDUFS8	-0.018429
CD81	-0.018322
IVD	0.018153
SDHA	-0.018030
GRB10	0.017915
IDH2	-0.017885
RPS25	-0.017735
ADK	-0.017709
UACA	-0.017654
ND5	-0.017635
RPS15A	-0.017538
NXF1	0.017526
NDUFB5	-0.017469
APRT	-0.017447
ZFP36L1	0.017424
CTDSP1	0.017423
BNIP3L	0.017414
NFIX	-0.017343
HNRNPU	0.017333
UQCR11	0.017253
VDAC1	-0.017251
ALDH6A1	0.017175
COX7A2L	-0.017171
PKIA	-0.017139
FN1	-0.017080
EIF3B	0.017076
PTN	-0.017011
FABP3	0.016982
EIF5B	0.016956
FDFT1	-0.016941
LGALS3	0.016938
METAP2	0.016931
MYADM	-0.016930
ARF4	-0.016880
MTDH	0.016872
SRPX	-0.016815
KLC1	0.016780
RPS5	0.016744
SSR3	0.016699
CPA1	-0.016685
GNG5	-0.016609
HIBADH	0.016554
RPL19	0.016475
RPL28	0.016474
RPL37	0.016440
SEPP1	0.016435
VIM	-0.016421
OXR1	-0.016416
RPL8	0.016335
CRP	-0.016301
CYTB	-0.016278
PRDX6	0.016260
BECN1	-0.016147
PXMP2	0.016124
SMAD3	-0.015977
PRKAR1A	-0.015840
SERBP1	-0.015791
TMA7	-0.015788
SERPING1	0.015719
SH3KBP1	-0.015682
DARS	0.015649
KANK2	0.015627
DDIT3	-0.015581
MFN2	-0.015536
PMEPA1	0.015526
RPL5	0.015341
ANXA5	-0.015249
CAPN3	-0.015206
PMP22	0.015180
CRYAB	0.015140
RAB5B	0.015093
GRB14	0.015074
IGFBP5	-0.014892
FAM160B2	-0.014842
GPD2	-0.014753
C1QB	0.014708
PPIB	-0.014703
ACTA1	0.014693
LIMS1	0.014644
PDIA6	-0.014486
PDHA1	0.014445
ND1	0.014415
NPEPPS	0.014415
COX8A	-0.014407
RPS9	0.014388
CNBP	0.014363
PAICS	-0.014354
CALU	-0.014254
CD48	-0.014234
CSRP1	-0.014222
LITAF	0.014203
PADI2	-0.014192
YBX3	0.014157
RAB12	0.014145
MRPL45	0.014079
CTSD	0.014066
GNPAT	0.014062
UBXN1	0.013924
XDH	0.013921
SLC25A5	-0.013907
SH2B2	-0.013855
SERPINE2	-0.013820
PSMC3	0.013776
S100A10	0.013758
CDKN1A	0.013675
ITGA1	0.013638
ARL4A	0.013624
AK3	-0.013567
NAPA	0.013562
GRPEL1	0.013556
ATP9B	-0.013540
NFYC	-0.013536
ACADS	0.013497
AKR1A1	-0.013439
TXNL1	0.013413
EIF3D	0.013329
RAB10	0.013321
DNPEP	-0.013315
DGAT1	0.013289
VAMP5	-0.013253
PNRC1	0.013206
ATP5D	-0.013195
RNASE4	0.013191
LMNA	0.013171
RPS27A	-0.013130
CYHR1	-0.013008
MYOG	-0.013002
RCN3	-0.012987
ACADVL	0.012959
CSDE1	-0.012947
NRP1	-0.012905
CDC37	-0.012898
URGCP	0.012841
BTG2	-0.012790
SDC4	0.012776
SGK1	-0.012717
ACSL1	-0.012699
LDB3	0.012674
PIK3IP1	-0.012626
SLC25A11	-0.012540
MYH2	-0.012513
ACOX1	0.012469
PIK3CD	-0.012451
RAB28	-0.012417
AZIN1	-0.012415
CMSS1	-0.012393
USP19	0.012387
NDUFAB1	-0.012347
ECI1	0.012341
BCKDHB	0.012329
CCT3	0.012273
MTCH2	0.012251
MMP23B	-0.012220
SDCBP	0.012204
RPL26	0.012195
TMEM255B	0.012194
GSTA5	0.012140
CIDEA	0.012136
BHLHE40	-0.012132
IDH3G	0.012129
GNB2	-0.012087
GM2A	-0.012075
CPQ	-0.012070
RPL24	0.012061
CNN3	-0.011965
EMP1	-0.011955
PRKCDBP	0.011927
NUP88	0.011917
JUN	-0.011900
PLK1	-0.011882
VPS45	0.011855
CXCR1	0.011854
CXCR4	0.011801
CGRRF1	-0.011771
APH1A	-0.011716
MGST2	0.011690
DLAT	-0.011674
PSMA2	0.011630
TNRC6B	-0.011559