!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!gene	PDK1
!cell	BrafV600E (Pten/-::Pdk1+/+)
!perturbation	Knockout
!disease	Melanoma
!end_metadata
SSPN	0.103036
GAL	0.100963
TAC1	0.098451
BRINP3	0.073187
SLC4A1	0.072776
SLPI	0.064744
ALAS2	0.063932
FOSB	0.063897
NPY	0.063097
TNN	0.058255
HIST1H2AB	-0.056621
ATP13A4	0.055680
EBF2	-0.055306
CSN3	-0.055224
ARNTL2	0.054050
FOXS1	-0.053884
COL26A1	-0.053444
NOTUM	0.052290
HBB	0.052194
SP5	0.051325
IL6	0.050147
PDRG1	0.050003
TREML1	0.049685
MEOX2	-0.049656
NXPH1	0.049542
MXD3	-0.049212
KDM5D	-0.049100
HIST1H2AA	-0.048618
RAD54L	-0.048526
CORIN	0.048170
IL10	0.047912
STRA6	-0.046456
FAM110C	0.045991
FAM84A	0.045726
KIF18B	-0.045353
CDCA8	-0.045352
CLU	0.045206
GDF10	-0.045017
HIST1H2AM	-0.044917
BRIP1	-0.044817
RAMP3	0.044708
KIF11	-0.044592
IL11	0.044417
HIST1H2AH	-0.044252
GREM1	0.044127
FOS	0.043802
SPC25	-0.043325
MCM3	-0.043112
SYBU	0.042843
REM2	0.042762
IQGAP3	-0.042650
CSRP1	0.042472
PTGES	0.042374
HIST1H2AJ	-0.042183
CENPM	-0.041942
HIST1H4H	0.041521
MEOX1	-0.041397
LUM	-0.041354
IL1B	0.041301
KIF23	-0.041236
CDCA2	-0.040851
GATA6	0.040835
KCNAB2	-0.040644
OSBP2	0.040626
SKA3	-0.040401
CCL11	-0.040365
ARHGEF39	-0.040264
TPMT	-0.040242
TNFRSF9	0.040093
CEP55	-0.039715
RAD54B	-0.039700
RAB6B	0.039483
FETUB	0.039331
HIST1H2AG	-0.039326
AMN	-0.039112
ASPM	-0.039070
GLDN	0.039035
MNS1	-0.039029
CLDN11	0.038982
SLC15A2	-0.038880
TRPC3	-0.038874
ALDH3A1	0.038857
FANCI	-0.038822
KRT8	-0.038765
SOX8	-0.038553
KIAA0101	-0.038403
RRM2	-0.038311
POLE	-0.038203
HIST1H4L	0.038112
FANCD2	-0.038055
ESCO2	-0.038011
ERCC6L	-0.038000
ARG1	-0.037942
OSR2	0.037919
PLK1	-0.037840
FGFR1OP2	0.037834
CYR61	0.037792
NUP210	-0.037655
CXCL3	0.037629
DUSP1	0.037467
CDCA3	-0.037403
KIF2C	-0.037316
COL28A1	-0.037293
TFAP2C	0.037096
CCNE2	-0.036931
COL23A1	0.036908
PRC1	-0.036820
STMN2	-0.036586
MCM10	-0.036534
CHTF18	-0.036485
KIF22	-0.036485
MCM5	-0.036323
FIGNL1	-0.036114
HMGCS2	0.035953
DEPDC1B	-0.035853
APCDD1	0.035777
SIGLEC1	-0.035542
MMP10	0.035539
BIRC5	-0.035416
FAM19A2	0.035416
MMD2	0.035246
FAM132B	-0.035113
PDK4	0.035066
THBS1	0.034821
CHAF1B	-0.034772
CENPI	-0.034723
CCNB1	-0.034689
KIF4A	-0.034642
ASPHD2	-0.034489
CLDN1	-0.034391
RORB	0.034376
SMOX	0.034325
SCRG1	0.034243
KRT27	-0.034129
PDE1A	0.034076
CDC20	-0.033999
PTPRN	0.033983
IER3	0.033876
B3GALT6	0.033695
FAM107A	0.033654
ACER2	0.033594
PLXDC1	-0.033514
KRT71	-0.033482
SPDL1	-0.033399
MMP3	0.033339
COL15A1	-0.033159
ADM	0.032990
HPSE	0.032936
C1QTNF2	-0.032765
TOP2A	-0.032752
FBXO2	0.032660
PIP5K1B	0.032621
SP7	-0.032451
CDH13	0.032422
PIF1	-0.032410
FBXO32	0.032288
KLK10	-0.032275
LCN2	0.032135
RBL1	-0.032107
PTX3	-0.032061
PIDD	-0.032016
WNT7B	0.031967
LGI3	0.031680
NTM	0.031673
CDCA7	-0.031532
ISLR2	-0.031455
SNCA	0.031453
AREG	0.031379
RUNDC3A	0.031367
HOXD8	0.031343
CRHBP	0.031331
RGS1	0.031307
ASF1B	-0.031279
HEYL	-0.031114
CKAP2L	-0.031041
IL4I1	-0.031022
SLC16A11	0.030957
CENPP	-0.030892
CENPN	-0.030878
KBTBD6	-0.030724
PTGS1	0.030680
SRPX	-0.030645
TENM4	0.030480
FAM64A	-0.030446
DLGAP5	-0.030397
AIG1	0.030378
CCDC80	-0.030338
WNT4	-0.030325
AURKA	-0.030288
NFIL3	0.030281
PBK	-0.030242
TPX2	-0.030031
MELK	-0.029953
TPBG	0.029945
SLC14A1	0.029943
RASL10A	0.029936
MMP12	0.029932
CRTAC1	-0.029872
NCAPH	-0.029845
CCL13	0.029832
CXCL2	0.029694
FAM19A4	0.029676
GRAMD4	0.029611
SLC22A4	0.029560
PHF19	-0.029510
BUB1B	-0.029482
NCAPD2	-0.029467
DLX1	-0.029391
ACE	0.029385
RAD51AP1	-0.029270
FCER1A	0.029241
HSD11B1	0.029226
NUDT6	0.029119
FGF7	0.029118
HIST2H2AB	-0.029088
CCL17	-0.029054
DCK	-0.029047
VAT1L	0.028981
CENPH	-0.028902
ATF3	0.028892
GDPD2	0.028873
UGT1A6	0.028848
F2RL3	-0.028847
HJURP	-0.028839
ZFP36	0.028758
WDHD1	-0.028717
RAPGEF6	-0.028539
SCG3	0.028504
SEMA4G	0.028481
CLEC11A	-0.028424
PLK4	-0.028423
ITGA7	0.028341
GZMH	0.028286
SOCS3	0.028238
MCM2	-0.028230
GPR34	-0.028210
HIST2H2AC	-0.028194
FAM20C	-0.028189
HIRIP3	-0.028133
GINS3	-0.028118
SLC2A6	-0.028094
FBN2	-0.028070
VMP1	0.028024
HIST1H4I	0.028011
TNFSF11	0.028003
TMEM179	0.027908
INCENP	-0.027833
ADH7	0.027741
TNFRSF18	-0.027739
NCMAP	-0.027558
TMEM108	0.027513
HIST1H4F	0.027480
CX3CR1	-0.027476
DLL1	0.027464
DUSP4	0.027460
SERINC2	-0.027356
PLA2G7	0.027306
OAS2	-0.027239
HDC	0.027239
CHST8	0.027118
RAMP1	-0.027104
ST8SIA2	-0.027041
CLDN10	0.027033
IPMK	0.027031
CHRD	0.026789
FOXG1	0.026659
TICAM2	-0.026651
STMN1	-0.026616
ROR2	-0.026616
SLIT2	0.026567
PTHLH	0.026509
RBP7	0.026460
GPR176	0.026448
SFRP1	-0.026436
THBS2	0.026423
PGM2L1	0.026397
CYB561	0.026396
GPATCH11	-0.026395
GNG8	0.026372
CXCL14	-0.026230
IRF7	-0.026161
SERPINB2	-0.026158
KRT34	-0.026107
TGIF1	0.026008
SMPDL3B	-0.025878
USP53	0.025861
AARD	0.025826
CSTA	0.025799
LMNB1	-0.025783
MS4A8	-0.025779
NAT8B	-0.025752
C14orf80	-0.025691
CLCF1	0.025676
RASL11A	-0.025672
FAM111A	-0.025643
RTN2	0.025569
YPEL5	0.025566
CCL5	-0.025559
HIST1H4K	0.025554
CDCA5	-0.025549
YIPF4	0.025545
POLD1	-0.025532
PTRF	0.025513
CTSW	-0.025431
TGFBR3	0.025431
CDC25C	-0.025418
MIS18BP1	-0.025324
UBE2T	-0.025282
HOXD4	0.025265
TBX2	-0.025199
ENO2	0.025186
PPM1L	0.025175
CCL4	0.025102
CLIC6	-0.025081
CMAS	0.025053
C8orf4	0.024902
MAPK13	0.024865
SH2D2A	-0.024834
POPDC3	0.024831
GP9	0.024793
PHF11	-0.024783
CITED2	0.024767
GPR183	-0.024711
TK1	-0.024711
TCF19	-0.024710
TWIST2	0.024654
NNMT	0.024653
RASGRF1	0.024621
LTB	-0.024498
FST	0.024459
MCM7	-0.024456
GPC3	-0.024432
CXCR3	0.024419
PKMYT1	-0.024260
SVEP1	-0.024251
CD3G	-0.024244
A4GALT	0.024224
FGD2	-0.024174
HIST1H4A	0.024142
SERPINB4	-0.024049
OPLAH	0.024010
BNC1	0.023999
RNASE6	-0.023950
MRVI1	-0.023937
COL9A2	-0.023936
H1FX	-0.023896
HELB	-0.023781
CD180	-0.023774
SLAMF9	-0.023766
TSC22D3	0.023754
CCL3L3	0.023749
EML5	0.023743
IL6R	0.023732
CTSV	0.023721
ATP12A	-0.023653
RRAGD	0.023624
FAM213A	0.023594
B3GNT3	0.023590
MYLK	-0.023584
CHAF1A	-0.023569
NDN	-0.023562
MYCL	-0.023553
LOX	-0.023535
NMRAL1	-0.023528
SMIM3	0.023483
TINAG	0.023451
CENPA	-0.023395
SGIP1	0.023315
MEDAG	0.023286
MSLN	0.023284
FOLR2	-0.023280
ADAMTS18	-0.023265
C8orf46	-0.023250
IL18R1	-0.023231
RNASE2	-0.023225
GTSE1	-0.023182
ZWILCH	-0.023179
MAD2L1	-0.023124
APOE	0.023102
TNFSF13B	-0.023095
KIAA1755	-0.023061
CAP1	0.023060
BMP3	-0.023041
EPS8	0.022998
DRP2	-0.022976
ZBTB46	-0.022919
FAM126A	0.022899
SLC10A6	0.022890
LIPH	0.022875
RRM1	-0.022847
FGFR1	0.022806
KRTDAP	-0.022795
CEBPB	0.022780
RASGRP3	-0.022767
ZDHHC14	0.022750
GFOD1	0.022696
HOXD9	0.022676
H2AFX	-0.022664
RPA2	-0.022663
ACTA2	-0.022660
GADD45A	0.022558
KRT73	-0.022557
KANK4	-0.022532
C10orf10	0.022531
TUBE1	-0.022513
ZCWPW1	-0.022513
SOSTDC1	-0.022495
ARTN	0.022434
SCG2	-0.022422
TMOD1	0.022416
ANXA4	-0.022413
CRYBA4	-0.022362
RASL12	-0.022360
SCX	0.022355
LMNB2	-0.022317
ETV1	0.022309
CLSPN	-0.022217
WISP2	0.022211
FOXM1	-0.022175
MTSS1L	0.022163
CD3D	-0.022160
TRIM62	-0.022160
FLYWCH2	-0.022127
VSIG4	-0.022046
ZNF235	0.022041
CDH19	0.022017
PEX5L	0.021994
DMP1	-0.021993
IL34	0.021977
RPTN	-0.021881
ANKRD61	-0.021869
ZNF365	-0.021867
AGTR1	0.021842
KIRREL3	-0.021838
SCARA5	0.021824
SERPINI1	-0.021794
MEIS2	0.021780
GDPD5	-0.021758
NDC80	-0.021756
KANSL1L	0.021732
PSMB9	-0.021683
FGD6	0.021656
SLC23A2	0.021654
RHOU	0.021641
VSTM2A	0.021628
SOX4	0.021616
NEURL1	-0.021613
KANK1	-0.021602
DIO3	-0.021597
DPP4	-0.021575
ESPL1	-0.021571
SEC14L2	-0.021518
PPP1R15A	0.021501
HIST2H4A	0.021499
IL1R2	0.021465
FCHO1	-0.021463
PDGFRB	-0.021458
RGS14	-0.021446
ISG15	-0.021413
HPGD	-0.021377
PDE1B	0.021371
IGF1R	0.021363
HIST1H4J	0.021358
PHGDH	-0.021348
RNASE1	-0.021345
YDJC	-0.021343
PDE10A	0.021311
FOSL1	0.021308
ADAM12	-0.021296
CDT1	-0.021287
GJB3	-0.021235
FGF1	-0.021202
CD3E	-0.021168
PGF	0.021165
PRELP	-0.021144
PNLIP	-0.021133
MVD	-0.021129
PSMC3IP	-0.021118
NPTX2	0.021080
CYP2S1	-0.021038
IL36RN	-0.021016
LRRC15	-0.020992
SATB1	0.020966
DAPK1	0.020948
PTPRO	-0.020932
TONSL	-0.020930
CLMP	0.020912
SLC7A11	0.020853
CALN1	-0.020826
RALGDS	0.020821
KRT86	-0.020770
C1orf112	-0.020735
ITGAV	0.020732
SUCNR1	0.020718
AIF1L	0.020694
HLA-DOA	-0.020689
MARCH4	0.020650
HCAR2	0.020647
RGS2	0.020595
ANGPTL7	0.020553