!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Doxorubicin
!smiles	CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
!drugbank_id	DB00997
!pubchem_cid	31703
!cell_type	A673
!organism	human
!end_metadata
MMP1	0.214355
KRT18	0.173482
MMP3	0.141102
HIST1H2BK	0.139427
FUCA1	0.114231
NELL2	-0.109276
ANXA1	0.109086
MKNK2	0.108262
RPL39	0.102724
PSMA1	-0.102121
GLO1	-0.095108
RAB13	0.092955
IARS	-0.091972
RPSA	0.091542
TMA7	0.089758
PHB2	-0.088200
MLLT11	-0.087019
MT2A	0.083952
TUBB	-0.080969
RPS27A	0.080584
TMSB4X	0.080545
PSMD14	-0.080155
TIMP1	0.079318
ATP1B3	0.078772
PABPC3	0.072868
CES1	0.072005
MRPL3	-0.071825
HIST1H4C	-0.071707
HMGN2	-0.071278
HNRNPA2B1	-0.070763
DYNC1I2	-0.069186
HIST1H2BD	0.066149
PFN2	-0.066060
CD63	0.065536
TMSB15A	-0.064043
YPEL5	0.063898
MCM6	-0.063275
ASNS	-0.063004
CCT3	-0.062783
PTGES3	-0.061923
ARL6IP1	0.060728
RPS23	0.060560
ATP5C1	-0.060467
MEST	0.059994
NRD1	-0.059958
HMGN3	-0.059192
CCT4	-0.058429
RPL3	-0.058067
SDCBP	0.057733
C20orf24	0.057559
CCT5	-0.057400
ATF4	-0.056524
TRMT5	-0.056131
ATP5E	0.055628
HIST1H2AC	0.055347
DLK1	0.054382
RPS27	0.054183
ARMCX6	0.054144
ATP1A1	0.052997
AKAP12	0.052289
TRIB1	0.051380
IRAK1BP1	-0.051376
CCNG1	-0.050922
SRSF3	-0.050276
NCKAP1	-0.049831
MTCH1	0.049771
H3F3A	-0.049519
GINS1	-0.048967
NGFRAP1	-0.048965
FTL	0.048595
RPL27	0.048501
BANF1	-0.048435
LDHA	-0.048089
ANXA2	0.048053
PABPC1	0.047987
ATP5G3	-0.047880
PEA15	0.047441
SLC25A5	-0.047061
CHCHD2	-0.046836
TUBB2A	0.046470
ATP6V1G1	0.046064
PSMA3	-0.046007
UTS2	0.045988
FTH1P5	0.045835
MDH1	-0.045806
S100A10	0.045788
HEXB	0.045514
PSMC1	-0.045454
DHX15	-0.045166
GMPS	-0.045021
FADS1	-0.044020
DNTTIP2	0.043977
RPLP1	0.043879
GINS2	-0.043610
ARMCX3	0.043199
EIF4EBP1	-0.043132
TUBA1A	0.042999
TFPI2	0.042867
CALM2	0.042841
ARPC5L	0.042608
HSPD1	-0.042533
PHLDA2	0.042270
HSPE1	-0.042132
VIM	0.041656
XRCC5	-0.041576
BASP1	-0.041203
UQCR11	0.040652
JTB	-0.040610
FAU	0.040559
PSMD1	-0.040546
IDH1	-0.040534
NME4	-0.040499
ADAR	-0.040371
HDAC1	0.040148
TXNDC5	-0.039932
B2M	0.039580
RPS21	0.039547
PSAP	0.039411
RPL10A	-0.039343
PSMB4	-0.039244
DDX1	-0.039209
HSD17B4	-0.039184
CXCL8	0.039103
OAT	0.038543
PRNP	0.038379
PBK	-0.038308
CLTC	-0.038284
H2AFY2	-0.038079
APEX1	-0.037935
RPS29	0.037839
CKS2	0.037752
MYL12B	0.037527
TRMT112	-0.037410
HNRNPR	-0.037364
CHST6	0.037352
HIST2H2AA3	0.037323
SNRPF	-0.037291
CS	-0.037236
YARS	-0.037230
LBH	0.037075
PCNA	-0.037067
NCOA4	0.037054
NDUFAB1	-0.036967
IMMT	-0.036910
IER3	0.036614
PHIP	-0.036589
OLFML3	-0.036408
UCP2	-0.036354
ANP32B	-0.036163
HSPA1A	-0.036039
PSMD7	-0.035985
ITGB3BP	-0.035923
FTH1	0.035817
RPF1	-0.035616
MSX1	0.035412
BTBD1	-0.035323
TAX1BP3	0.034885
RPS25	0.034739
GMNN	-0.034464
SOD1	-0.034456
NSA2	-0.034355
DARS	-0.034355
ZNF280A	0.034289
UQCRC1	-0.034213
TUBB6	0.034189
RRAGC	0.034142
RPA3	-0.034110
TUBB4B	-0.033921
MYL6	0.033902
EIF3C	-0.033690
PHGDH	-0.033640
CLTA	0.033567
HAT1	-0.033311
NDUFB4	-0.033050
BTG1	0.033011
RND3	0.032943
PKIG	0.032877
COL1A2	-0.032876
COX7C	-0.032727
BLCAP	0.032509
PRDX1	0.032475
DYNLT1	-0.032261
SNX3	-0.032248
GNG11	0.032195
EIF2S2	-0.031876
RPL21	0.031583
HINT1	-0.031543
SRSF2	-0.031420
RHBDL2	-0.031172
WBP5	0.031007
SSRP1	-0.030929
TMSB10	0.030929
DLD	-0.030827
PTPRK	-0.030818
ARF3	-0.030787
GLA	0.030567
DENR	0.030414
FAM21A	0.030377
DBI	-0.030345
CFL1	0.030336
HAX1	-0.030280
RPS24	0.030268
GCSH	-0.030178
FBN2	-0.030021
KIAA0101	-0.029946
LITAF	0.029812
SARS	-0.029728
HPRT1	-0.029691
UBE2C	0.029473
EIF4H	-0.029299
BRD2	0.029293
FLNC	0.029219
RPS16	-0.029194
ARF4	0.029129
WDR12	-0.029083
PPIB	-0.029031
TYMS	-0.028980
PSMC2	-0.028969
DHCR24	0.028963
CKS1B	0.028961
PDE1A	-0.028959
MAPK6	-0.028854
CBS	-0.028802
PNP	0.028706
RPS3	0.028688
RPL8	0.028628
MAFB	0.028627
ATP5A1	-0.028562
RPS5	0.028540
ARHGEF6	-0.028490
MORF4L1	-0.028441
KPNA2	0.028434
ACAT2	-0.028293
FAM162A	-0.028268
UPP1	0.028231
HNRNPC	-0.028181
RPL41	-0.028167
FNBP1	-0.028125
BUB1B	-0.027964
MMD	-0.027810
RPL28	0.027787
CACYBP	-0.027781
GNPAT	-0.027779
PPA2	-0.027661
UBA52	0.027589
HSD17B12	-0.027556
COX6B1	-0.027467
AARS	-0.027432
TAGLN2	0.027398
RBM15	0.027366
ACTN1	0.027174
LTA4H	-0.027130
MORF4L2	-0.027123
SRP9	-0.027008
EEF2	0.026980
VBP1	-0.026905
PIR	-0.026813
NAE1	-0.026727
HN1	0.026632
PDHA1	-0.026551
HSPA5	0.026508
HIRA	-0.026507
DSTN	0.026482
TPM2	0.026367
MARS	-0.026281
PGAM1	-0.026268
CTSL	0.026203
HNRNPA3	-0.026128
KRT8	0.025999
RPL37	0.025989
ARPC2	0.025958
STX3	0.025890
GLG1	-0.025863
SERPINE2	0.025859
ROBO1	-0.025849
TBCB	-0.025798
C1QBP	-0.025787
CEP55	-0.025770
TPT1	0.025734
EIF4A2	0.025667
HNRNPK	-0.025585
CSE1L	-0.025548
NCL	0.025530
ITM2A	0.025467
POLR2G	-0.025458
EFNB2	0.025376
LAMP1	0.025338
ANP32E	-0.025337
ATXN10	-0.025281
GOLT1B	0.025262
NDUFA13	-0.025205
RPL17	-0.025201
GABARAPL2	-0.025043
ILF2	-0.024902
TAF10	-0.024900
RPL12	0.024711
HSD17B10	-0.024621
TPM1	0.024563
CRYZ	-0.024548
RBMX	-0.024511
RPL14	0.024511
NKX2-2	-0.024442
ESD	-0.024417
UQCRQ	-0.024408
MAFF	0.024295
TIMM8B	-0.024246
LRRC47	0.024202
SGK1	0.024185
PCBP1	-0.024155
MAGED1	-0.024151
ACTB	-0.024026
NTS	0.023973
ATP1B1	0.023881
RGS5	0.023853
PSMB7	-0.023824
GBAS	-0.023776
DDX39B	-0.023768
SEC61G	-0.023713
PSMD2	0.023674
GNL2	0.023662
UBE2E3	-0.023616
POLR2L	0.023501
EEF1A1	0.023429
MIF	-0.023375
ENO2	-0.023359
ATP5O	-0.023304
AMIGO2	0.023181
ETFA	-0.023059
EIF4B	-0.023054
EMG1	-0.023019
GNB1	-0.023001
MAP1LC3B	0.022890
PRIM1	-0.022800
VRK1	-0.022759
PSMG2	-0.022744
XPOT	-0.022699
RAP1B	0.022687
RCN1	0.022680
KDM1A	-0.022667
SRSF4	-0.022667
IGFBP2	-0.022646
EPB41L2	-0.022638
DCLRE1A	-0.022596
LAPTM4A	0.022562
DUSP6	0.022549
C14orf166	-0.022517
SAC3D1	-0.022514
VOPP1	0.022513
CCBL2	-0.022505
YRDC	0.022470
SCD	-0.022437
NPC2	0.022395
COX7B	-0.022343
GSTA4	-0.022342
MRPL16	-0.022340
IARS2	-0.022326
PLK2	0.022280
NDUFB6	-0.022193
FAM21C	0.022170
FKBP1A	0.022154
SHMT2	-0.022134
MTCH2	-0.022070
BNIP3	-0.022063
ALDH2	-0.022051
DAPK1	-0.022028
SHC1	0.021927
COX8A	-0.021896
DUT	-0.021892
RPS19	0.021875
TOP1	0.021803
HYOU1	-0.021800
DPM1	0.021775
DDIT4	-0.021764
NDUFA9	-0.021743
SRI	-0.021723
RPL34	0.021694
SNRPD2	-0.021690
RNASEH2A	-0.021679
BAG3	0.021672
PSMC6	-0.021620
GADD45A	0.021581
FABP5	0.021580
PDIA3	-0.021570
VDAC2	-0.021539
DLGAP5	-0.021485
CDC34	0.021475
GPNMB	0.021472
PDIA6	-0.021453
THYN1	-0.021443
PFKP	-0.021414
GARS	-0.021383
RPL24	0.021355
VCP	-0.021352
PTRH2	0.021257
AHCY	-0.021219
CYC1	-0.021187
RPL4	-0.021183
RDX	-0.021102
PSMA6	-0.021081
MMADHC	-0.021069
PNRC2	-0.021023
PSAT1	-0.021018
FAM35A	-0.021013
ATP6V0E1	0.021002
POLR3K	-0.020963
MELK	-0.020963
NAT10	-0.020951
CDC37	0.020930
LY96	0.020928
FADS2	-0.020873
SNRPA	-0.020842
TALDO1	-0.020820
PDHB	-0.020806
MCM3	-0.020780
ARHGAP29	0.020767
RFC4	-0.020716
TCEA1	-0.020715
RPL13	-0.020688
GAPDH	-0.020663
EIF6	0.020566
MATR3	-0.020509
MRPL39	-0.020436
ZFAND5	0.020394
DDX50	-0.020366
ATP6V0D1	0.020344
TOR1B	0.020307
DYNLT3	-0.020302
CAPRIN1	-0.020298
YWHAE	-0.020285
GPN1	-0.020265
DNM1L	-0.020236
PDCD6IP	-0.020225
TUBB3	-0.020192
PSMD6	-0.020182
CAPNS1	-0.020174
BAG6	-0.020171
TRIM8	0.020140
GOT2	-0.020137
UBAP2	0.020136
RPS4X	0.020115
CDK2AP1	-0.020101
FAM171A1	-0.020089
GNAS	-0.020067
HIGD1A	-0.020045
NDUFS1	-0.020033
ATP5F1	-0.019983
MRPS35	-0.019959
VPS51	-0.019957
SF3A3	-0.019940
ARL8B	0.019929
PRMT1	-0.019925
YBX1	0.019898
NUDT11	-0.019878
ACAT1	-0.019869
RPL11	0.019866
DCTN2	-0.019842
RGS10	0.019827
MYL12A	0.019785
RPL38	0.019769
SLC24A3	-0.019717
ANXA5	0.019700
HSPA9	-0.019692
CD81	0.019654
DNMT1	-0.019613
SNRPB	-0.019613
UCK2	-0.019600
S100P	0.019554
PSMA5	-0.019523
PSMB6	-0.019496
HSPB1	-0.019454
RPN2	-0.019445
RPL18	0.019329
LAMTOR5	-0.019270
CDKN3	-0.019232
RPL29	-0.019220
SNRPB2	0.019051
NUP37	-0.019042
IER5	0.018992
SLC5A3	0.018976
TM9SF3	0.018946
SMC4	-0.018940
RARS	-0.018938
PSMD4	-0.018936
RIN2	0.018913
PPA1	-0.018878
TCEB2	0.018856
ESF1	0.018847
COCH	-0.018799
PTTG1	-0.018735
TMED10	-0.018723
PRKCB	-0.018715
HCLS1	0.018703
GSTO1	-0.018693
PLA2G4A	-0.018653
NAA50	0.018626
PSMD12	-0.018618
PSMC4	-0.018615
NET1	0.018603
ACTR10	-0.018600
RRM1	-0.018570