!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!drug_name	Rosiglitazone
!smiles	O=C1NC(=O)C(S1)Cc1ccc(cc1)OCCN(c1ccccn1)C
!drugbank_id	DB00412
!cell_type	NA
!organism	rat
!end_metadata
FABP4	0.259645
INMT	0.208249
PAH	-0.154664
RETSAT	0.124554
PCK1	0.121807
CTSV	-0.117280
KLK3	0.113828
GPX3	-0.108925
UCP1	0.107543
TFF3	0.097339
GSTP1	0.096034
CD36	0.092479
SLC22A2	0.090833
PROM1	-0.090446
PLAU	-0.083289
DAB2	-0.083246
AKR1A1	-0.081667
NAPSA	-0.080002
ATP1B1	0.079929
FABP5	0.078535
FMO3	0.076074
CNDP2	-0.074893
MAT2A	0.072722
COMT	-0.068093
LPL	0.064284
NAT8B	-0.063696
RPL31	-0.063575
BSG	-0.063438
ACSM3	0.063175
SPP1	-0.062624
ALDH6A1	0.062399
CTSB	-0.062139
ATP5L	-0.061583
SLC3A1	0.060508
SLC34A1	-0.060170
SCD	-0.060116
SLC17A3	-0.059878
CIDEA	0.059742
GSS	-0.059460
SOD1	-0.058912
FTL	-0.058263
SOSTDC1	0.057834
NCOA4	0.057435
ATP1A1	0.057377
CST3	-0.056899
CRYAB	0.056249
APMAP	-0.056241
LACTB2	-0.055986
CA3	0.055299
PLLP	-0.054889
AADAT	-0.054794
AHCY	0.053970
HAAO	-0.053620
ID2	0.052726
ND1	0.052534
CTSA	-0.050750
ACSS2	-0.050315
AQP2	-0.049405
PDZK1IP1	-0.048906
SLC17A1	-0.048868
HSP90B1	-0.048800
TMEM27	-0.048673
CNDP1	-0.048640
DAO	-0.048634
GCSH	-0.048608
PGRMC1	-0.048326
ACY1	-0.048287
FTH1	-0.048286
SLC15A2	0.047248
CYS1	-0.047177
OSGIN1	-0.046221
RPL7A	-0.046203
SLC6A6	0.045974
PGPEP1	-0.045723
FABP3	0.045660
CCNG1	-0.045567
NID1	-0.045257
HRSP12	-0.045126
GRINA	-0.044664
PRDX5	0.044450
CALB1	0.044230
GPR56	-0.044165
TMLHE	-0.044083
ACTG1	0.044044
COTL1	-0.044004
IGFBP7	0.043844
NDUFB9	0.043509
CLIC1	-0.043181
MATN1	0.043030
MEP1A	0.042799
GABARAPL1	-0.042376
HAO2	0.042112
EGR1	0.041924
MTCH1	-0.041852
PHYH	0.041764
GLYAT	-0.041639
UBD	-0.041621
LDHB	0.041257
NME2	-0.040835
CCBL1	-0.040661
TMIGD1	-0.040314
SLC7A13	0.040292
ALDH9A1	-0.040133
RPS2	-0.040003
CPQ	-0.039983
UMOD	0.039725
CD63	-0.039550
SULT1B1	-0.039549
RPS5	-0.038774
PTER	-0.038441
APOM	-0.038420
FAHD2B	-0.038369
GNPNAT1	0.038278
RPS11	-0.038004
DHRS7	-0.037794
ATP5H	-0.037779
MIOX	-0.037030
CALML4	-0.036720
SLC4A11	0.036549
PIGR	0.036238
MYH10	0.036098
CISD1	0.036052
OSBPL8	0.035979
RPL10	0.035587
G6PC	0.035425
F2R	0.035375
RPL26	0.035348
ERRFI1	-0.035238
CTDSP2	-0.035186
HSPE1	-0.035147
TMEM174	-0.034980
ATP5G3	-0.034954
PLAC8	-0.034900
SMIM24	-0.034856
TINAG	-0.034511
PRDX1	-0.034467
ESD	-0.034322
HSD11B1	-0.034314
IGSF11	-0.034291
TSC22D1	-0.034288
AP2S1	-0.034030
HINT2	-0.033942
RPS16	0.033834
DDT	-0.033704
PSAT1	-0.033674
RPS29	-0.033356
SLC25A5	0.033171
RGN	0.033132
NIT2	-0.033081
PTGES3	-0.033025
FUCA1	-0.033013
LRP2	-0.032862
SLC34A2	-0.032845
ALDH1A1	0.032826
ID4	0.032443
ACADSB	0.032252
PPP2R1B	-0.032183
S100A6	0.032180
LAPTM4A	0.031965
TPP1	-0.031850
MRPS33	-0.031719
FCER1G	-0.031647
COL4A2	-0.031636
ATP6V0D1	-0.031485
CHDH	-0.031460
PTH1R	-0.031395
RPS3	-0.031390
SUCLG2	-0.031236
PRSS35	0.031180
XYLB	-0.031056
TMA7	-0.031032
SLC25A4	0.031007
ESPN	-0.030926
ACLY	-0.030817
CD74	-0.030769
ND2	0.030629
TMBIM6	0.030619
IER3	0.030610
SLC26A1	-0.030501
TIMM8B	-0.030330
TMEM30A	0.030290
NAT8	0.030196
RPS9	-0.030182
KCNJ1	0.030141
SDC4	-0.030095
COX1	0.030052
NUDT4	0.029931
SLC27A2	-0.029812
BCL6	0.029800
FBP1	-0.029797
SDHC	-0.029672
MGST3	0.029612
FXYD4	-0.029446
CALR	-0.029345
CYP1A1	0.029215
CLTA	-0.029067
ND3	-0.029032
RPL5	0.028971
POLR2L	-0.028906
IL33	-0.028894
AMACR	-0.028882
ATP5D	-0.028799
IDH1	-0.028732
HDAC6	-0.028576
IAH1	-0.028567
ASPA	-0.028548
COX6A1	-0.028523
SLC13A3	0.028461
QDPR	-0.028445
TPMT	-0.028395
RHOB	-0.028338
DPP7	-0.028313
ZFP36	0.028235
ODC1	-0.028003
ID1	0.027927
PCBP1	0.027926
NR4A1	0.027868
SLC22A1	-0.027831
AQP3	0.027747
KMO	-0.027666
GLUL	0.027523
FHL1	0.027397
EMCN	0.027365
PDIA3	-0.027335
TMEM37	-0.027307
NOP10	-0.027216
SORD	-0.027194
NME7	-0.027189
ADIPOR1	-0.027159
OAT	0.027031
SCN1B	0.026997
SERF2	-0.026917
CCRN4L	0.026634
RPN2	-0.026589
DHX15	0.026557
HMGN1	-0.026501
CASKIN2	0.026429
LGALS1	0.026331
COX14	-0.026321
LITAF	-0.026311
SNRPD2	0.026253
CPT1B	0.026235
RELL1	-0.026206
MGLL	-0.026155
CCNI	-0.026136
APOPT1	0.026017
KDELR2	0.025954
GNG13	0.025924
ATP5B	-0.025900
NDRG2	0.025898
IRS2	-0.025772
ATP1A2	0.025739
TUBA4A	0.025671
GCDH	0.025670
ARG2	0.025661
RESP18	-0.025661
ME1	0.025654
DBI	-0.025584
GPRC5C	-0.025545
RPL8	-0.025517
MLC1	0.025349
HNF1B	0.025347
ABCB10	0.025143
ACADL	0.025142
NDUFA3	0.025129
RBM3	0.025101
SLC29A3	-0.025061
IDH3G	-0.025033
ARL4D	0.024969
TSPAN3	-0.024877
DNASE1	0.024811
ANPEP	-0.024772
PPP1R1A	0.024761
SACM1L	0.024752
ACADM	0.024735
CYCS	0.024586
SUGCT	0.024574
ABCG2	-0.024522
HSPA5	-0.024491
ALDH7A1	-0.024456
RPN1	-0.024456
DPP4	0.024385
UGP2	0.024344
COX4I1	-0.024339
NDUFB3	-0.024335
SMG9	-0.024335
CCND1	0.024327
ECHS1	0.024314
ALDH2	-0.024289
PSMB2	0.024145
RBP7	0.024114
CKB	0.024113
SLC26A4	0.024112
STARD10	0.024053
GATM	-0.023894
PRELID1	-0.023886
SLC13A2	0.023834
RPS15A	0.023831
SLC7A9	-0.023788
CCDC6	-0.023774
GNL3L	-0.023762
SLC22A18	-0.023711
ACOX1	0.023682
CA2	0.023643
CSRP2	0.023642
RTN4	0.023608
PIM3	0.023605
ARPC4	0.023547
SLC47A1	-0.023486
GLRX5	-0.023361
CXCL16	-0.023181
SARNP	0.023176
CMAS	-0.023139
NPY	-0.023066
NQO2	-0.023015
COX5A	0.022950
DDAH1	-0.022944
GOT1	0.022857
STEAP4	0.022793
HIBADH	0.022691
UQCRQ	0.022653
PPDPF	-0.022589
DDX5	0.022538
TFCP2L1	0.022475
PRDX3	0.022378
UBL3	-0.022373
FXR2	-0.022341
SLC22A12	-0.022305
PF4	-0.022280
HYKK	0.022253
ARCN1	0.022232
RBP4	-0.022183
PCBD1	-0.022172
EPHX1	-0.022086
GGCT	-0.022080
IVNS1ABP	0.022069
IGFBP5	0.022056
SMAGP	-0.021995
RAP1GAP	0.021880
MECOM	0.021851
GRN	-0.021843
RNF10	-0.021841
HSD17B12	0.021840
AK2	0.021827
SLC12A1	-0.021791
ALG9	-0.021721
SAP18	-0.021664
PREP	-0.021645
GPX1	-0.021594
ABHD17C	-0.021590
ATP6V1G3	0.021498
RPS12	-0.021489
NAA38	-0.021478
TEX264	-0.021459
DNPEP	-0.021451
CIB1	-0.021388
RASL12	-0.021341
UGDH	-0.021322
GGH	0.021290
SERINC3	-0.021279
BSND	0.021216
SLC25A10	0.021195
UQCRC2	-0.021187
MRFAP1	0.021152
FKBP9	-0.021140
TMEM176A	-0.021130
PDHB	0.021119
MYLIP	0.021112
RBKS	-0.021103
EGF	0.021089
TMEM98	-0.021081
PCCB	0.021070
ERGIC3	-0.020836
YWHAQ	0.020827
TRRAP	-0.020809
FST	-0.020739
NDRG1	-0.020722
TMEM140	-0.020720
ARL2BP	-0.020694
MID1IP1	0.020684
STOM	-0.020665
S100A4	0.020655
VDAC3	0.020639
KHK	0.020565
SRI	-0.020517
CLDN10	-0.020495
SPCS1	-0.020481
COLEC12	0.020474
ILF2	0.020443
GRPEL1	0.020440
POMP	-0.020423
KDELR1	-0.020390
PHYHD1	-0.020334
MCL1	-0.020275
IFI30	-0.020262
COX8A	-0.020227
SLC6A18	-0.020184
OAZ1	-0.020152
TEK	0.020136
MIPEP	-0.020097
LAMP2	-0.020091
HSP90AB1	-0.019990
BCAT2	0.019944
GGT1	-0.019936
CLPTM1L	-0.019906
OPLAH	-0.019866
COPZ1	-0.019861
ANAPC13	-0.019857
HSD17B4	0.019853
RAB8A	-0.019787
ACSL1	0.019779
TRMT112	-0.019765
TMEM50A	-0.019761
ZDHHC6	-0.019721
MCCC2	-0.019709
ECHDC2	0.019707
PRLR	0.019703
VCP	-0.019607
THUMPD1	-0.019530
PTTG1IP	-0.019523
ITGB1	-0.019483
LRRC58	0.019478
RCE1	-0.019443
ABHD14B	-0.019366
HOXD9	-0.019323
CHPT1	-0.019244
ATP5J2	0.019193
PXMP4	-0.019177
DAD1	-0.019128
MBD2	-0.019116
NID2	-0.019115
NIT1	-0.019114
FN1	0.019113
FAHD1	-0.019083
MAPKAPK2	-0.019047
VPS35	-0.019033
NDST1	0.019027
MSN	-0.019012
STMN1	-0.018972
HACL1	0.018950
AK3	-0.018941
CLIC4	-0.018940
GSTM1	0.018898
HSP90AA1	-0.018897
COMMD3	-0.018843
RPS7	0.018801
SLC17A5	0.018793
EIF5A	-0.018773
IGF2R	-0.018732
SREBF1	0.018703
BTD	-0.018690
RHOBTB1	-0.018688
SPP2	0.018659
ACSS1	0.018600
ENY2	-0.018555
CIDEB	-0.018524
SEMA4B	-0.018484
SPINT2	-0.018474
DHCR24	-0.018471
HSPA8	-0.018429
LASP1	-0.018403
CLDN2	-0.018394
EDF1	-0.018369
TMEM256	-0.018328
RPL14	0.018311
DNAJC19	-0.018298
NDUFB11	0.018280
KCNJ16	0.018249
TINAGL1	0.018195
ADIPOQ	0.018159
EHHADH	0.018158
PPP1CA	-0.018129
CMBL	-0.018092
LDB1	-0.018092
SMIM22	-0.018063
NDUFA12	-0.018055
DCTN1	-0.018027
NDUFB7	-0.018019
RPL11	0.018002
PDGFRA	-0.017987
RHCG	0.017942
ARPC3	-0.017925
SLC25A30	0.017872
CDHR5	-0.017858
HSPD1	-0.017830
PGAM1	0.017815
SGK1	0.017809
SFXN1	-0.017808
JUNB	0.017753
UCP2	-0.017735
PPIC	0.017723
TNFAIP8	-0.017715
HSD11B2	-0.017697
TALDO1	-0.017688
G0S2	0.017676
ATP6V0E2	-0.017673
SEPT4	0.017662
MMD	-0.017660
DYNLL1	-0.017649
SLC13A1	-0.017611