!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Doxorubicin
!smiles	CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
!drugbank_id	DB00997
!pubchem_cid	31703
!cell_type	SCC25 tongue epidermal keratinocyte
!organism	human
!end_metadata
VASN	0.067174
RASD1	0.062176
GLRX	0.060295
ID2	0.060258
TUBB2B	0.056570
FUCA1	0.055611
CCNA1	0.055184
HIST3H2A	0.053966
SH3PXD2A	-0.053887
CEBPA	0.053692
CRISPLD2	0.052171
EPHX1	0.051962
ULBP2	0.051779
SPANXA2	0.051686
OLR1	0.050935
NEU1	0.050333
S100A2	-0.049851
ZNF280A	0.049213
BAMBI	0.048853
IFIT2	0.048514
FOXO4	0.048373
FAM46A	0.047711
SCG5	-0.047243
RARRES3	0.046996
EFHD1	0.046302
TMEM27	0.046103
FOXQ1	0.046026
ULBP1	0.045682
CLIC3	0.045277
CITED2	0.044932
THBS1	-0.044778
FAM222A	0.044173
PLCH2	-0.043662
RTTN	-0.043159
SERPINE1	-0.042919
FAM64A	0.042579
LPXN	-0.042562
H2AFJ	0.042459
TUBB3	0.042015
MMP9	-0.041948
YPEL5	0.041887
SNHG9	0.041713
ZCCHC12	0.041098
EPOR	0.041086
SNAR-A1	-0.040684
CRTAC1	0.040270
AKR1B10	0.039903
IDH1	0.039747
HIST2H2BE	0.039544
ENDOG	0.039440
NXF1	0.039146
CYSRT1	0.038950
KRT13	0.038721
CSRP2	0.038635
CTGF	0.038535
SPANXC	0.038068
PLEK2	-0.037609
CARD10	-0.037608
CABYR	0.037507
PLAT	0.037271
MAP1LC3B	0.037154
PTGES	0.036720
TRAFD1	0.036688
CDK2AP2	0.036609
MAFB	0.036593
HIST1H4H	0.036311
CLDN7	0.036201
LDLR	-0.036199
POLR2A	0.036100
FAM109A	0.036044
CKB	0.035971
GTF2B	0.035822
HIST2H2AA4	0.035751
FSTL1	0.035638
BCAR3	-0.035637
CSPG4	-0.035538
HIST1H2AE	0.035418
UCA1	0.035395
CRABP2	0.035376
SNAI2	-0.035170
FOSB	0.035146
HIST2H2AC	0.035071
INSM2	0.035046
CCND2	-0.035000
SLPI	0.034994
FRAT2	0.034989
COL22A1	-0.034930
CDIPT	0.034887
HIST1H3F	0.034865
BCL6	0.034812
VPREB3	0.034784
SLC4A11	0.034695
GABARAPL1	0.034605
HNRNPA1P33	-0.034390
SPANXA1	0.034356
CHCHD7	0.034181
ALPP	0.034018
ESPN	0.033879
HSPA2	0.033790
TMEM2	0.033782
SLC30A3	0.033776
PGD	0.033765
TUBB2A	0.033725
BAIAP2L2	-0.033650
SLU7	0.033573
C7orf50	-0.033524
HIST2H2AA3	0.033460
FOS	0.033330
ASF1B	0.033245
MAPKAPK3	-0.033202
DDIT3	0.033182
CCL26	0.033179
OASL	0.033149
SAMD9	0.032901
HERC5	0.032881
GADD45B	0.032819
CA2	0.032785
IGFL1	0.032649
SOX8	0.032468
NEFH	0.032411
IL1A	-0.032394
RAC2	-0.032392
CBR3	0.032328
SRSF1	-0.032251
CREG1	0.032239
UBE3B	0.032168
IQCD	0.032158
MICB	0.032148
KCTD13	0.032092
CLDN1	0.032087
ACTA2	0.031979
IL1B	-0.031884
LSM2	-0.031873
KRT80	0.031854
SERTAD4-AS1	0.031845
HIST1H3H	0.031824
ADSL	-0.031810
DLX3	0.031788
CCM2L	0.031746
SLC16A3	0.031722
CENPT	0.031650
HOXC13	0.031469
HSPB8	0.031264
C1orf61	0.031238
SERTAD1	0.031175
RGCC	0.031125
LOC729970	0.031079
NUDT16L1	0.031026
CSRNP2	0.031003
HOXD1	0.031002
CTSV	0.030993
GSTT2	0.030732
TUBB	-0.030729
FAM107B	0.030517
RBM14	-0.030504
ARID5B	0.030489
NMB	0.030421
SERPINB1	0.030406
TNFSF10	0.030398
ANXA2R	0.030236
G0S2	-0.030185
NINJ1	0.030159
MYLIP	0.030159
IL6	0.030016
RAET1G	0.029925
C16orf93	0.029880
MPC2	0.029874
ATG2A	0.029722
SOX9	0.029660
DUSP5	0.029522
RHOBTB3	0.029502
NARF	0.029378
COMMD7	-0.029320
CGN	0.029131
GSTM3	0.029050
LAMC2	-0.029043
NAPRT	-0.028973
KIFC2	0.028958
HIST1H2BF	0.028925
GMFB	-0.028925
KRT8	0.028908
ACSS1	0.028705
PPP2R3C	0.028684
NFE2L1	0.028672
TMBIM4	-0.028657
GPRC5A	0.028630
S100A3	-0.028604
NCKAP5L	0.028492
MOK	-0.028491
PLSCR3	-0.028486
CBX4	0.028447
HIST1H3D	0.028445
CDK6	-0.028430
TNC	-0.028329
GNA15	-0.028304
NTF3	0.028299
CDC26	-0.028295
MRPS10	-0.028293
LPP	-0.028153
HIST1H2AM	0.028147
IRF3	0.028138
HAPLN3	0.028127
FERMT1	-0.028056
CD27-AS1	0.028018
TMEM158	0.028000
CYP1B1	0.027968
SLC16A10	0.027946
DPH5	-0.027893
LINC00936	0.027870
SAAL1	-0.027838
CST6	0.027688
EPRS	-0.027680
SOX18	0.027660
SLC6A8	0.027588
KDM5B	0.027588
CDH11	-0.027542
EPHA2	0.027500
SLC7A1	-0.027471
HAUS7	-0.027471
MRFAP1	-0.027430
MARCKSL1	0.027326
GALR2	0.027311
STC2	0.027292
CABLES1	0.027280
FBP1	0.027215
GPSM2	-0.027191
RAI14	-0.027119
ZBED2	-0.027115
GFI1	0.027113
IFIT3	0.027057
NT5C	-0.027005
CDC25B	0.027002
NOV	0.026997
USP18	0.026975
ADM	0.026963
ACE2	0.026958
GDF15	0.026895
CHMP4A	-0.026806
PTGS2	-0.026747
CCDC3	0.026735
CD70	0.026590
RP9	-0.026588
ADIRF	0.026578
GNB1	-0.026539
FAM136A	-0.026478
SLC30A1	0.026474
RBM38	0.026403
HCP5	0.026326
IRX2	0.026286
AP3B2	0.026278
C20orf27	-0.026223
HBP1	0.026148
NRIP3	0.026115
MRPL15	-0.026040
CAV2	-0.025996
GSTO2	-0.025992
MXD4	0.025946
CDKN1C	0.025868
SORL1	-0.025847
TXNRD1	0.025843
ABTB2	0.025831
TNFSF9	0.025791
PTPMT1	-0.025785
EXOSC8	-0.025784
ITGA2	-0.025780
ACTG1	-0.025752
SRPRB	-0.025731
PTPRK	-0.025709
OVOL2	0.025693
ALPPL2	0.025689
DEDD2	0.025542
FOXC1	0.025522
MAP3K7CL	-0.025515
RPS7	-0.025484
HTATIP2	0.025430
TPCN2	-0.025403
ZCCHC17	0.025365
SPSB1	0.025365
SDC4	0.025364
TMEM138	-0.025359
GADD45G	0.025325
IL13RA2	-0.025320
DPYD	-0.025152
RNF39	0.025150
TK1	0.025117
TRIM26	0.025084
HIST1H3G	0.025019
GSTO1	-0.025000
SKIDA1	0.024993
POU3F1	0.024905
BCKDK	-0.024884
C9orf89	0.024859
ZNF488	0.024809
RHBDD2	0.024724
AGPAT2	0.024723
TRA2B	-0.024702
MTSS1	-0.024695
HIST1H2AC	0.024671
PTDSS1	0.024643
HLA-E	0.024591
ETS1	-0.024585
LPCAT3	0.024580
TP53INP2	0.024534
HCFC1R1	0.024490
ARHGEF17	0.024487
PFAS	-0.024479
CCL20	-0.024452
UBE2E2	-0.024451
VPS29	-0.024436
ZCCHC24	0.024393
MCOLN1	0.024349
SLC44A2	0.024290
NIPAL3	0.024286
SPANXD	0.024276
KLF9	0.024271
TRIB3	-0.024259
CRELD2	0.024248
TRABD	-0.024233
EIF3A	-0.024212
TOR1B	0.024144
ITFG3	0.024136
CTSK	-0.024127
HBA2	0.024082
SLC37A4	-0.024070
AP1M1	-0.024066
CHMP1B	0.024049
PTMS	0.024035
COQ3	-0.023974
APOD	0.023928
RFTN1	-0.023859
NDUFA2	0.023830
NTN4	0.023830
ACLY	0.023830
RAD9A	0.023800
HEATR1	-0.023794
TSPAN5	-0.023784
DUSP19	0.023772
PTHLH	-0.023748
SUPT4H1	0.023713
MLEC	0.023709
SLC25A22	-0.023675
TUBA4A	0.023670
BRMS1	0.023645
HDDC2	-0.023600
TENM3	-0.023591
MRGBP	-0.023589
INPP4B	-0.023582
FLOT1	0.023534
FADS1	0.023516
HS3ST2	0.023487
ABHD15	0.023477
ADCK3	0.023457
PLA2G15	0.023457
NT5C3A	0.023448
BRAT1	-0.023422
SAT1	0.023378
SSR1	-0.023373
NAA38	0.023371
RRAGA	0.023371
TFAP2C	0.023343
PPM1F	-0.023342
CLDN12	-0.023341
STMN3	-0.023329
ARPC5	-0.023324
SLC41A1	0.023287
NAT10	-0.023279
ISG15	0.023270
NADSYN1	0.023257
SLC44A3	0.023240
RNF167	0.023237
TMEM45A	0.023196
CHST7	0.023190
TWIST1	0.023127
TIPARP	-0.023125
FAM83A	-0.023106
PATL1	-0.023061
SF3A3	-0.023060
SYNCRIP	-0.023045
ZW10	-0.023005
GPX8	-0.022969
ARL2BP	-0.022965
NUTF2	-0.022952
MALL	-0.022941
ARC	0.022939
GSK3B	-0.022915
DCXR	0.022911
DBI	0.022908
PTPN11	-0.022903
SPOCD1	-0.022894
IMPA2	0.022889
TRAPPC3	-0.022858
C17orf96	0.022836
PI3	0.022827
CDCA4	-0.022779
LYPD1	0.022749
IFIH1	0.022728
FZD9	0.022704
KIAA2013	0.022685
DIO3	0.022679
KRT3	0.022673
NXN	-0.022668
GARS	-0.022659
TRIP13	-0.022654
MAGT1	0.022649
F3	-0.022645
DUSP1	0.022607
TMEM154	-0.022597
C18orf8	0.022576
CCNF	-0.022531
LCP1	-0.022483
POR	0.022481
RRAS	-0.022463
SFXN4	-0.022449
WDR54	-0.022447
HNRNPD	-0.022438
CXADR	0.022434
MIR205	-0.022399
RTCA	-0.022294
DIRC2	0.022291
DUSP28	0.022263
ACTN1	-0.022236
IRF7	0.022225
PGAP2	-0.022217
LINC00294	0.022202
SRSF6	-0.022198
TOMM20	-0.022191
EVL	-0.022182
IFI30	0.022145
MSX1	0.022132
MLF2	0.022088
TMEM134	0.022084
HBEGF	0.022050
ISYNA1	0.022043
SOWAHC	-0.022026
BTG2	0.022017
SLC13A5	0.022003
RSRP1	0.021995
EIF4A3	0.021977
KRT9	0.021942
OAT	0.021936
AMTN	-0.021934
MYH10	0.021883
MRPS6	0.021875
ZNF22	-0.021871
FGF19	0.021841
NSMCE4A	-0.021841
ALDH18A1	-0.021810
HOOK2	0.021803
DUS2	-0.021795
MOAP1	0.021791
RTP4	0.021770
STAT2	0.021765
RNF181	0.021755
SLC25A4	0.021752
COBLL1	0.021744
CDT1	-0.021725
ANKRD37	0.021717
PPP1CC	-0.021706
FAM84B	0.021618
COQ10A	0.021615
DHDH	0.021572
FURIN	0.021533
FAM210B	0.021493
METTL5	-0.021488
RPP25	0.021473
TCTEX1D2	-0.021469
PIGU	-0.021467
PDCD2L	-0.021442
TMEM60	0.021434
RPL21	-0.021416
CRIP1	0.021402
SMIM14	0.021382
TMEM140	0.021375
MAFG-AS1	0.021371
TIGD5	-0.021369
HOXA5	0.021342
EIF4A2	-0.021330
RDH10	0.021291
DRG1	-0.021260
TMEM171	0.021248
DOLK	0.021232
FBXO32	0.021229
PPL	0.021167
EIF2B2	0.021166
TIMP2	0.021161
RBM3	-0.021154
MED20	-0.021141
C10orf35	-0.021140
HELZ2	0.021123
EPHA4	0.021116
ATP1A1	0.021113
C12orf57	0.021113
RNF19B	0.021101
CMSS1	-0.021090
CNKSR3	0.021089
JAG1	-0.021086
C1orf174	-0.021081
DAPK1	0.021076
NUP37	-0.021052
ANO1	-0.021040