!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	MCF-7 cells
!organism	human
!end_metadata
VTCN1	-0.092668
PTGS2	0.091105
PLAC1	0.081799
COL21A1	0.079351
CXCL12	0.078532
GNE	-0.075186
NPY1R	0.074835
HCAR3	-0.073840
CXCL10	0.070750
TMPRSS3	0.069680
MMP13	0.069456
CCL2	0.068880
LMO3	-0.068308
BIRC3	0.066753
EGR3	0.065659
TFF1	0.065124
BLNK	-0.064967
PRSS23	0.064225
PGR	0.063887
IL17RB	0.062281
PLAT	0.061883
TM4SF1	-0.060450
STON1	-0.059623
PDZK1	0.058630
WISP2	0.057359
FOS	0.057006
IGFBP3	-0.056306
CALML5	-0.055778
MYBL1	0.055411
OLFML3	0.054708
OLFML2A	0.054530
KIAA0226L	0.054404
SGK1	0.053613
ASB9	-0.052427
FGB	0.052161
PMAIP1	0.050945
ODAM	-0.050725
EPB41L3	0.050713
IGFBP4	0.050164
LINC00341	0.050077
RNF43	-0.049326
CEACAM6	-0.048540
SYTL2	-0.048206
IRF6	-0.048138
ABCG2	0.047574
PIK3IP1	-0.046658
CAV1	0.045573
RAB31	0.045234
AGR2	0.045164
CCNG2	-0.044965
FGG	0.044028
CXCL8	0.044007
PCP4	0.043789
RIN2	-0.043758
TCN1	0.043576
HOXC6	0.043570
GABRE	-0.043495
TTR	0.043401
VEGFC	-0.043349
C1QTNF3	-0.043265
TSPAN5	0.043030
CYP4B1	-0.042598
TSPAN8	-0.042539
PARM1	0.042229
CXCL11	0.042124
HOXC4	0.042058
CCDC176	-0.041925
GREB1	0.041832
KLRC3	0.041459
IL1R1	-0.041438
ISG20	0.041429
TNF	0.041376
HCRP1	-0.041289
AREG	0.040892
KRT81	-0.040575
CXCL1	0.040516
TPD52L1	0.040140
RHOBTB3	0.039712
PARP8	-0.039557
BIK	-0.039076
ENDOD1	0.038780
DOCK4	0.038737
SLC19A2	0.038665
TLR2	0.038598
LIF	0.038532
EXO1	0.038318
TBX3	-0.038199
JAM2	-0.038142
LEPREL1	0.037983
FHL2	0.037859
DHRS3	-0.037657
FAM189A2	0.037534
APOBEC3A	-0.037381
UCP2	-0.037272
SH2D4A	-0.036767
ELOVL2	0.036721
TSPAN12	-0.036654
SOX3	0.036633
TGFB3	-0.036619
OPN3	0.036612
ORC1	0.036357
AOX1	0.036013
SPANXC	-0.035925
PDZD2	-0.035797
KLHL24	-0.035785
BAMBI	-0.035652
ASCL1	0.035613
SEC14L2	0.035279
NEDD4L	-0.035256
CCL20	0.035218
LIMA1	-0.035096
LINC00597	-0.034685
CAPN15	0.034625
PTK6	-0.034623
RBKS	-0.034493
CA12	0.034396
FAM216A	0.034306
ALDH4A1	-0.034304
RCAN2	-0.034287
SGCG	-0.034261
MBOAT2	-0.034046
ANKRD1	0.033833
PPP1R3C	-0.033832
CLMN	-0.033785
NAIP	-0.033695
SLC17A5	-0.033642
LMCD1	-0.033533
LRP2	-0.033335
INSIG2	-0.033290
ABCC5	-0.033259
LAMP3	-0.033219
PRR14L	0.033164
RET	0.033115
RAMP1	0.033017
ING4	-0.032955
RASL11B	-0.032889
AKR1B10	-0.032882
ANGPTL4	-0.032810
GRB14	-0.032799
SFTPA2	0.032737
SIDT1	-0.032706
TFPI2	0.032625
CRISP3	-0.032582
KIF15	0.032568
UPK1A	-0.032549
DEPTOR	0.032543
SYCP2	-0.032470
FOXC1	0.032325
ATP7B	-0.032302
RPRM	-0.032299
CD83	0.032261
HOXC5	0.032231
PPOX	-0.031997
PROCR	0.031937
MOCOS	0.031724
AURKB	0.031722
NRIP1	0.031716
ARHGAP11A	0.031690
MCM10	0.031675
ENC1	-0.031622
CALCR	0.031598
ID1	0.031592
S100A7	0.031587
RND1	-0.031470
BAG2	0.031426
KCNK5	0.031398
HIST2H2BE	-0.031330
TFF2	0.031320
TNFSF15	-0.031223
GDPD3	-0.031197
CXCL3	0.031190
POLQ	0.031082
SLC7A5	0.031011
ANXA3	-0.030914
TSGA10	-0.030858
RAB26	-0.030814
ZNF750	-0.030673
ZNF185	-0.030568
IFI44L	-0.030506
BCL2A1	0.030369
OSMR	0.030367
CXCR4	-0.030300
GRIA2	0.030292
TMEM135	-0.030204
HIST1H2AC	-0.030159
KCNN2	-0.030147
SLC4A8	-0.030004
TNFSF10	-0.030000
SLC12A5	-0.029791
NBEA	-0.029783
GLB1L2	0.029720
CA5B	-0.029616
TARP	-0.029542
SYBU	0.029524
VASH2	-0.029483
MAMLD1	0.029479
TIPARP	0.029444
CDC6	0.029425
SUV39H2	0.029396
MGC12488	-0.029375
ASRGL1	0.029334
CD47	-0.029289
SUOX	-0.028996
FKBP4	0.028868
LRRC1	-0.028854
PELI2	-0.028808
SIAH2	0.028789
GLTSCR1	-0.028643
ABCC4	-0.028625
ADAMTS1	0.028470
CA8	0.028322
PODXL	0.028080
F5	0.028050
A2M	-0.027983
LAMB3	0.027982
RAD54L	0.027977
FGF13	-0.027972
PALMD	-0.027954
MYC	0.027941
ASF1B	0.027859
NUDT6	-0.027832
ACPP	-0.027826
COL4A5	-0.027806
CXADR	-0.027770
CXCL2	0.027732
TMEM158	0.027729
MYO19	0.027550
ACSS3	-0.027473
GPNMB	-0.027433
GRINA	-0.027399
MATK	0.027394
ABCG1	-0.027235
PCOLCE2	0.027070
SLC16A7	0.027058
TXLNG	0.027041
LYPD3	-0.026981
ATP8A1	-0.026965
ATXN1	-0.026940
ELF5	-0.026915
SLC52A2	0.026873
SELENBP1	-0.026863
SMYD2	-0.026845
ZNF254	-0.026756
EFEMP1	-0.026738
RAB27B	-0.026738
NPM3	0.026725
DDC	-0.026708
LRP8	0.026703
SIK1	0.026679
BBS7	0.026650
APOLD1	-0.026624
MYBL2	0.026616
FAM134B	-0.026538
PPIF	0.026515
KCNV1	0.026468
HDAC7	-0.026443
SLC2A10	-0.026417
TTC33	-0.026389
ENPP2	0.026363
TAF5	0.026313
ZNF571	-0.026293
THNSL2	-0.026226
FAM114A1	-0.026213
GAS1	-0.025867
C1orf21	-0.025817
IL1RAP	0.025804
PDGFRL	0.025792
C11orf95	-0.025771
EFHD1	-0.025736
ACKR3	-0.025649
CTSO	-0.025643
PIK3R3	-0.025593
FABP5	0.025466
TTC30A	-0.025446
NEIL1	-0.025438
UTP20	0.025418
PRRG4	0.025366
FN1	0.025354
STC2	0.025346
UCK2	0.025329
CDCA3	0.025291
MYO1B	-0.025275
SREK1IP1	0.025226
AUNIP	0.025181
NCS1	0.025155
TMC5	-0.025124
ATP6V0A4	-0.025065
ARID5B	-0.025050
TFF3	0.024971
NAT1	0.024947
GLA	0.024942
IQCC	0.024906
CAMK2N1	-0.024889
EPB41L5	-0.024822
RND3	-0.024757
KIAA0020	0.024740
NOL6	0.024670
CD24	-0.024507
MBTD1	-0.024503
SATB1	-0.024490
NR1D2	-0.024473
PMP22	-0.024344
GSAP	-0.024306
NELL2	-0.024295
CTSH	-0.024239
DZANK1	-0.024196
RASGRP1	0.024179
CHEK1	0.024144
HIPK2	0.024101
ID4	0.024086
PKMYT1	0.024067
TRAM2	-0.024029
SDC2	0.023898
YPEL5	-0.023895
POLI	-0.023877
MMD	-0.023842
RUNDC3B	-0.023838
TRIM68	-0.023832
GAL	0.023805
BCAS3	-0.023753
FZD4	-0.023723
SNHG3	0.023682
KIF2C	0.023673
CD55	-0.023649
GINS4	0.023622
SEPP1	-0.023615
UBE2S	0.023603
ABHD2	0.023595
NME1	0.023579
ZFP2	-0.023531
SYT17	-0.023433
TPK1	-0.023429
TRIP13	0.023404
HILPDA	-0.023335
RPS6KA5	-0.023333
ARHGAP12	-0.023279
PIK3C2B	-0.023269
PRSS8	-0.023248
FADS1	0.023213
COA7	0.023180
TMEM97	0.023177
ASAP3	-0.023159
TIPIN	0.023156
NDRG1	-0.023152
HAUS7	0.023068
EMG1	0.023060
TUBB6	0.023023
PAQR6	-0.023014
SERPINB9	0.023004
GAD1	0.023003
ZNF211	-0.022979
AUH	-0.022975
PUS1	0.022967
CDC45	0.022874
CCDC86	0.022835
PADI2	-0.022820
SEC14L5	-0.022808
VGLL1	-0.022807
CDCA8	0.022804
CHRNA5	0.022801
PAK3	-0.022736
DDIT4	-0.022694
MANEA	0.022693
ZMYND8	-0.022683
KAT2B	-0.022675
HIST1H2BC	-0.022603
PLEKHF2	-0.022587
DDX10	0.022562
KIAA0513	-0.022551
TSPAN1	-0.022532
NOLC1	0.022475
UBE2C	0.022463
LOC100272216	-0.022426
SH3BP4	-0.022416
TCOF1	0.022393
ECH1	-0.022376
PDSS1	0.022374
CCDC28A	-0.022363
RTN2	-0.022325
GSTA4	-0.022302
WDR74	0.022286
MRTO4	0.022272
DHRS2	0.022248
RBBP8	0.022237
CSTA	-0.022232
SESN1	-0.022218
ZBTB10	-0.022189
CLPB	0.022184
TAOK1	-0.022167
HIST1H3H	-0.022158
GNAI1	-0.022100
FBN2	-0.022048
SMG9	0.022029
GFOD1	0.022006
FKBP14	0.021969
PER3	-0.021886
TFEB	-0.021837
MAGED2	-0.021804
UBIAD1	0.021794
C1orf115	-0.021730
SLC22A5	0.021729
NET1	-0.021724
SLIT2	-0.021709
PLBD1	-0.021709
LPIN2	-0.021694
INHBB	-0.021679
ARHGEF40	-0.021635
IFIT1	-0.021615
SLC39A6	0.021587
CLU	-0.021576
RELB	0.021568
URB2	0.021567
WNT4	0.021553
PLSCR4	-0.021546
IFRD2	0.021516
POP1	0.021508
ZWILCH	0.021505
CHST8	0.021499
PCMTD2	-0.021497
SH3BGRL	-0.021495
FILIP1L	-0.021492
PIBF1	-0.021483
CUEDC1	0.021479
CDH3	-0.021436
PAPSS2	0.021434
FNDC3B	0.021430
FJX1	0.021406
PPP1R9A	-0.021397
FAM13A	-0.021396
DPH2	0.021361
SLCO4C1	-0.021360
ERCC6L	0.021357
HIST1H2AG	-0.021354
SCAI	-0.021316
ARHGEF10L	-0.021238
CBX6	-0.021232
LAMB1	-0.021212
SKA1	0.021211
ZNF83	-0.021188
RNF130	-0.021153
TNS3	-0.021147
GINS2	0.021134
POLR3K	0.021129
UCHL3	0.021125
KCTD12	0.021125
LHFP	0.021104
HAUS6	0.021096
ATP2B1	-0.021094
TACC3	0.021082
SEMA3B	0.021074
RHBDF2	0.021062
CLDN1	-0.021052
IFI44	-0.021049
METTL1	0.021021
CALML4	0.021012
SLC24A3	-0.020987
RASSF8	0.020978
SLC7A6	0.020973
SRM	0.020969
ATG14	-0.020965
DTL	0.020961
LDOC1	-0.020957
CERK	-0.020927
CHAF1A	0.020917
PLK2	-0.020915
SASH1	-0.020901
L1CAM	-0.020901
C1orf106	-0.020896
RABEP1	0.020839
ACSL3	-0.020832
ATP2C2	-0.020817
DCAF13	0.020788
RAB20	-0.020779
DRAM1	-0.020778
BCAS1	-0.020757
DLEU1	0.020723
SLCO4A1	0.020723
BRCA2	0.020715
XPO4	0.020691
SCCPDH	-0.020685
CTNND2	-0.020640
SPC25	0.020630
OAT	-0.020607
CDV3	0.020574
SHROOM2	-0.020554
DCLK1	-0.020553
GUSBP3	-0.020546
HIST1H3F	0.020541
MYO6	-0.020502
EXOSC5	0.020486
TENC1	-0.020477
RNF126	0.020465
HOPX	-0.020459
FBXL6	0.020439
HEY1	-0.020435
GLRB	0.020398
PPAN	0.020389
WNT5A	0.020380
MUC1	-0.020374
FTSJ1	0.020366