!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Cisplatin
!smiles	N.N.Cl[Pt+2]Cl
!drugbank_id	DB00515
!pubchem_cid	441203
!cell_type	HeyA8 ovarian carcinoma cell line
!organism	human
!end_metadata
GDF15	0.086703
TNFSF4	0.074183
HIST1H2BM	-0.070737
CXCR4	0.062021
HIST1H3J	-0.060039
TXNIP	0.059348
CCND2	0.058116
HIST1H2AB	-0.052933
TLR4	0.051630
HIST1H2AJ	-0.049343
TP53INP1	0.048403
DCLK1	0.047894
GPR87	0.047367
IL7R	0.047300
ANKRD1	0.046442
TGFA	0.045753
PLAT	0.045550
DDIT3	0.045509
HIST1H2AK	-0.045132
MAMDC2	0.044605
HIST1H1D	-0.043796
HIST1H2BI	-0.043794
HIST1H1A	-0.043484
IGFBP5	0.043388
MCM6	-0.043325
FAM111B	-0.043170
HIST1H4B	-0.042322
IL1B	0.041695
CSMD3	0.041667
HIST2H4B	-0.041221
HIST2H4A	-0.041221
NID2	0.040983
LACC1	0.040909
DYSF	0.040468
RRAD	0.040339
SLC16A12	0.039840
TNFSF15	0.039565
TRIM55	0.039490
HIST1H2BF	-0.039326
HIST1H1B	-0.039256
HIST1H2BB	-0.038898
PSTPIP2	0.038862
FUCA1	0.038821
SPATA18	0.038516
BTG2	0.038241
HIST1H2AL	-0.038161
ADHFE1	0.037961
GALNT5	0.037908
CRYAB	0.037517
CPA4	0.037067
WDR76	-0.036828
GPRC5B	0.036747
HIST1H1C	-0.036481
GMFG	0.036310
CDKN1A	0.036213
HIST1H2AH	-0.036064
IGFBP7	0.036064
NOG	0.035723
HIST1H3F	-0.035681
NLRP10	0.035622
HIST1H2BH	-0.035472
SERINC2	0.035289
HIST1H3A	-0.035094
SAT1	0.035069
TSPAN1	0.035051
HIST1H2AM	-0.034911
CD82	0.034798
GINS2	-0.034762
CDCA7	-0.034649
CCDC148	0.034505
CLDN1	0.033929
ICAM1	0.033924
HIST1H4D	-0.033870
PAG1	0.033822
MYH16	0.033339
HIST1H3B	-0.033255
S100A4	0.033084
SCN2A	0.032952
SLAMF7	0.032866
IL24	0.032761
CD274	0.032688
STC1	0.032587
CD70	0.032269
HIST2H2AB	-0.032105
UBA7	0.032082
LOXL4	0.032034
DLEU2	-0.031905
SGK223	0.031631
ATP6V0A4	0.031600
CCNE2	-0.031566
KCNJ2	0.031483
MR1	0.031453
HIST1H2AE	-0.031445
TOB1	0.031443
UNG	-0.031260
SERPINE2	0.031224
XPC	0.031132
HIST1H2AI	-0.031084
SNORD30	-0.031063
MCM3	-0.031003
HIST1H2BL	-0.030937
FABP3	0.030830
DSC3	0.030684
HSD11B1	0.030675
IRAK2	0.030455
E2F8	-0.030419
PTX3	0.030302
SMOC1	0.030272
FAM81A	-0.030247
CLSPN	-0.030059
MCM5	-0.029954
SMIM14	0.029832
PLA2G4A	-0.029797
HIST1H2BK	-0.029631
FDXR	0.029597
LIPH	0.029467
HIST1H2BC	-0.029411
TMEM40	0.029400
HIST1H1E	-0.029394
MCM10	-0.029303
SNORD116-14	0.029275
KIF15	-0.029192
SAA1	0.029132
EML2	0.029061
TENM2	0.028983
LINC01152	0.028968
FRMD5	0.028882
HIST1H4C	-0.028827
SAA2	0.028801
COL1A1	0.028650
PTPN22	0.028484
MCM4	-0.028413
DUSP5	0.028341
ALOX5AP	0.028326
SESN1	0.027870
HIST1H3H	-0.027792
CNIH3	0.027777
INPP5D	0.027776
FBXW7	0.027750
ITGA2	0.027634
ACER2	0.027613
RGS4	0.027584
SERPINF1	0.027578
CDC45	-0.027569
PRKG1	-0.027542
ORC1	-0.027441
FERMT3	0.027402
HSD17B14	0.027368
MCM2	-0.027362
LRRC17	0.027194
HIST1H3C	-0.027172
THSD1	0.027148
RBMY2EP	0.027121
CALML4	-0.027091
CHAF1B	-0.027022
LRP1	0.026894
SNORD50B	-0.026884
GPR110	0.026708
SNORD116-21	0.026708
STAG1	-0.026690
POLE2	-0.026588
NCF2	0.026556
TM7SF2	0.026350
TMEM173	0.026243
HIST1H4L	-0.026230
ADAMTS5	0.026050
LIPK	0.025949
JPH1	-0.025923
KITLG	0.025866
PGPEP1	0.025860
SPC25	-0.025847
PPME1	0.025843
CITED2	0.025838
CD163L1	0.025757
C4BPB	0.025746
SULF2	0.025603
PRKAR2B	-0.025557
HELLS	-0.025528
FEZ1	0.025404
SIRPG	0.025333
EBI3	0.025300
DSCC1	-0.025219
DRAM1	0.025216
ST6GALNAC3	-0.025127
TRIML2	0.025124
ESCO2	-0.025020
HIST1H3I	-0.024956
CASK	0.024916
SLC22A15	0.024837
TGFB2	0.024763
SNORD116-20	0.024683
ITGB4	0.024573
GABPB1	-0.024569
EXO1	-0.024545
MMS22L	-0.024505
NDUFAF4	-0.024502
SNORD116-15	0.024490
SERPINB5	0.024412
LRRN4CL	0.024366
HIST3H2A	-0.024358
DDB2	0.024260
GPD2	-0.024240
APOBEC3C	0.024062
NREP	0.024014
LAMP3	0.023967
DGKA	0.023945
DEPDC1B	-0.023936
RRM2B	0.023887
LGALS9	-0.023849
PDLIM1	0.023848
AADAT	-0.023759
DNA2	-0.023684
CDC7	-0.023654
KISS1	0.023614
HIST1H4A	-0.023592
TMEM229B	0.023585
HIST1H2BO	-0.023552
LINC00518	0.023527
S100A2	0.023501
APOBEC3H	0.023500
ADAMTS12	0.023405
PIGW	-0.023384
ELOVL2	-0.023326
CDC6	-0.023282
NUPR1	0.023282
CXCL8	0.023219
SULT1C2	0.023203
CYFIP2	0.023174
PIK3IP1	0.023148
SLC12A8	0.023145
CHEK1	-0.023134
ARRDC3	0.023123
IFI30	0.023070
PFN4	0.023063
COL4A5	0.023058
SAA4	0.023046
FAS	0.023010
RFC4	-0.022989
ITGB8	0.022972
UCP2	0.022852
CDK17	-0.022848
PLCD3	0.022841
ANKRA2	0.022753
POLA1	-0.022709
CALCOCO1	0.022670
HIST1H2BJ	-0.022638
RINL	0.022632
MFGE8	0.022613
S100A3	0.022573
DDIT4L	0.022541
GSN	0.022513
ANGPTL2	0.022483
TRAPPC6A	0.022461
HIST2H2AC	-0.022458
BIRC3	0.022376
XRCC2	-0.022371
ATAD5	-0.022333
HIST1H2BG	-0.022312
MIR15B	-0.022219
SDC2	0.022218
MKNK2	0.022200
FREM2	-0.022148
STYXL1	0.022117
PWAR6	0.022068
WDR63	0.022028
CHAC2	-0.022020
FST	0.022014
SEMA3B	0.022009
ZNF737	-0.021942
PLK4	-0.021908
LRRC34	-0.021903
TIPIN	-0.021899
TNFRSF11B	0.021874
ALDH1L2	0.021852
SLC2A3	0.021811
AMPD3	0.021795
FJX1	-0.021786
SLC16A6	0.021771
LINC00341	0.021757
MNS1	-0.021748
CES4A	0.021668
MND1	-0.021636
RAD51AP1	-0.021630
LOC100506990	-0.021625
SNAPC1	-0.021544
SERTAD4	-0.021518
CDCA3	-0.021497
GMNN	-0.021496
USP1	-0.021429
SSBP2	-0.021409
ESPL1	-0.021397
CDKN2C	-0.021386
SNORA75	-0.021379
FAM84B	0.021372
KDM5B	0.021301
ALPK2	0.021244
PTCHD4	0.021241
DIS3L	-0.021232
NTSR1	0.021183
HIST1H3G	-0.021077
CBLB	0.021075
C22orf46	0.021063
CDC25A	-0.021035
TEP1	0.020996
FLG	0.020987
IFI44	0.020949
CCDC138	-0.020948
SHISA3	-0.020940
HIST1H4H	-0.020905
LURAP1L	0.020903
RGS5	0.020902
KCNN4	0.020853
FAM71D	0.020836
SLC16A7	-0.020820
SESN3	0.020797
POLD3	-0.020784
MDM2	0.020783
GRAMD3	0.020782
LRP8	-0.020773
KRT80	0.020726
OR52K3P	0.020726
JPH2	0.020673
AREG	0.020635
DUT	-0.020611
SLCO1A2	0.020570
C5orf34	-0.020567
JUNB	0.020565
RNU5D-1	-0.020553
ISOC1	-0.020546
PLXNB2	0.020536
CA2	-0.020510
RARRES3	0.020501
ACSS3	0.020464
PARPBP	-0.020463
STAT4	0.020457
ANKRD29	0.020410
MCM7	-0.020387
WDR17	-0.020369
NCAPH	-0.020369
PSG4	0.020350
ZNF367	-0.020334
HSD17B2	0.020294
FABP4	0.020288
TSEN2	-0.020228
FEN1	-0.020201
RAD51	-0.020193
SNORA62	-0.020185
FBXO32	0.020117
GALNT15	0.020079
SNORD116-28	0.020053
KIAA1217	0.020044
ARID5B	0.020038
TCP11L2	0.020003
PHLDA3	0.019965
PHLDB1	0.019960
ZWINT	-0.019955
PCAT4	0.019947
LRRCC1	-0.019940
MSLN	0.019929
MSH6	-0.019927
POLR3B	-0.019903
KIAA0247	0.019885
LPXN	0.019880
TPCN1	0.019879
CARD16	0.019851
LOC1720	-0.019844
PCDH18	-0.019841
CES2	0.019823
C3AR1	0.019811
CD46	0.019795
REEP6	0.019789
LOX	0.019742
ICAM2	0.019732
SH2D2A	0.019679
CEP152	-0.019679
C1orf116	0.019668
BLOC1S2	0.019664
LMNB1	-0.019662
BMP4	0.019650
BDKRB1	0.019633
SNORD52	-0.019617
RFC5	-0.019558
STOM	0.019546
MAP2	0.019522
FHL2	0.019512
DTL	-0.019508
RBL1	-0.019495
ITGA10	0.019475
WIPI1	0.019455
ORAI3	0.019437
ADARB1	0.019379
RMI1	-0.019377
BLM	-0.019373
SNORA6	-0.019361
C1RL	0.019337
MKI67	-0.019334
DCP1B	0.019320
EDA2R	0.019302
CENPK	-0.019253
FHIT	-0.019250
CDR1	0.019235
EVI2B	0.019230
CLDN7	0.019163
F3	0.019159
KIF11	-0.019151
SCFD2	-0.019130
CCNF	-0.019130
SHROOM3	0.019095
CEP78	-0.019086
SLC7A2	-0.019046
OR5M10	-0.019032
OSBPL3	0.019016
GPR17	-0.019013
MDM1	-0.019011
USP44	0.019008
C1orf112	-0.018966
RAB27B	0.018965
TRIM8	0.018961
IL1RAPL1	0.018955
MTHFD1	-0.018927
SNORD14E	-0.018922
CYP4F11	0.018905
GAS6	0.018865
ZFYVE1	0.018862
SCN5A	0.018856
CEP135	-0.018856
ASS1	0.018828
KNTC1	-0.018827
SERPINH1	0.018799
NDRG1	0.018772
ORC6	-0.018766
HBEGF	0.018743
EHF	0.018736
P2RX4	0.018728
UCA1	0.018720
IER3	0.018704
HIST1H2AG	-0.018700
PCNXL2	0.018698
LRRIQ1	-0.018695
ASRGL1	-0.018674
TRAF3IP2	0.018630
PDGFD	-0.018597
TGFBI	0.018585
ULBP3	-0.018577
MYBL2	-0.018566
ISCU	0.018564
UBR7	-0.018540
MTSS1	0.018534
SKA1	-0.018506
LAPTM5	0.018479
TCEA3	0.018469
BTG1	0.018456
SFRP1	-0.018454
CSF1	0.018440
SYT14	-0.018439
KIFC1	-0.018439
SNORD20	-0.018438
CASC5	-0.018410
MIS18BP1	-0.018398
HAUS2	-0.018380
MYLK	0.018375
MTERF3	-0.018374
TAF5	-0.018365
PPM1D	0.018357
ACTBL2	0.018353
C3	0.018348
ATAD2	-0.018331
TSGA10	0.018308
OR13H1	-0.018268
PNRC1	0.018253
HSP90AA6P	-0.018252
ACVRL1	0.018247
CCDC51	0.018246
CDCP1	0.018244
NDC1	-0.018232
WARS	0.018225
FAM83B	-0.018202
RPEL1	-0.018196
TM6SF1	0.018189
VEGFA	0.018138
IFI44L	0.018120
PLD3	0.018117
SMC2	-0.018113
ABCG2	-0.018098
RELB	0.018075
MARCO	0.018056
XYLB	-0.018052
THOC1	-0.018033
B3GNT5	-0.018015
FANCM	-0.017996
ZNF841	0.017986
DSN1	-0.017960
RAVER2	-0.017960
CKAP2L	-0.017957
HHIP	0.017937
DENND2C	0.017928
SNORA33	-0.017927
INHBE	0.017917
GNGT2	0.017887
PBK	-0.017876