!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	PubChemCID:5757
!cell_type	MCF7cells
!organism	human
!end_metadata
IFI27	0.111895
VTN	0.090413
APOD	0.089343
SGCE	-0.084821
MUCL1	0.083266
BST2	0.082832
CDH10	-0.075531
NME4	-0.074802
SHISA2	0.070399
ZNF175	-0.068496
H19	0.068477
PLEKHS1	-0.066696
SIGLEC6	-0.066428
S1PR3	0.065426
KRT81	0.065316
ACTG2	0.064338
VTCN1	-0.063877
KIAA1324	0.062725
ABCC2	0.062116
SLC2A3	-0.060934
TEX19	0.060835
PRSS23	0.060699
ANXA1	0.060650
HIST1H4H	0.060634
CYP26B1	0.060576
CTGF	-0.060385
HSPB8	0.060349
ZNF22	-0.060305
STC1	-0.058920
GJA1	-0.056623
TIMP3	0.055949
NDRG1	-0.055627
GPNMB	0.055415
GGT6	0.053601
TARP	0.051159
TM4SF4	0.048770
SUSD2	0.048641
MT2A	-0.048567
C1orf106	0.048385
AKR1C3	0.047878
MT1A	-0.046607
SLC2A10	0.046092
TENM3	0.045856
ERP27	0.045813
GHDC	0.045743
CLDN1	0.045346
PMEL	0.045342
DNASE1L2	0.044997
NRCAM	0.043640
C9orf152	0.042750
EDN1	-0.042485
CEACAM5	0.042245
SCARNA13	0.042229
RHOBTB3	0.042166
TSKU	0.042028
PMS2P4	0.042016
DNAJA4	0.041931
MT1X	-0.041793
MMP10	-0.041575
ACTA2	-0.041276
UPK3A	0.041120
EFHD1	-0.041102
TFF3	-0.040354
NPHP3	-0.040208
CDC45	-0.040196
CYP4B1	0.040009
MOB3B	-0.039862
CAPN9	0.039073
PAQR7	0.038885
PALLD	0.038830
FAM214A	-0.038730
HIST1H2AC	0.038695
IFI6	0.038576
MYO16	0.038525
AOX1	0.038190
ANXA3	0.038175
CRABP1	0.038174
TK1	-0.038140
NUPR1	0.038101
HBEGF	0.037848
PYGL	-0.037506
ALCAM	-0.037492
GULP1	0.037444
QPRT	0.037357
ADIRF	0.037240
KRT24	-0.036910
LIMCH1	-0.036356
DUSP16	0.036309
CDKN2B	0.035787
ISG15	0.035617
ARPP19	-0.035585
SERPINE2	-0.035572
GFRA1	0.035507
PRR11	-0.035460
MESP1	0.035262
GBP2	0.035059
LEO1	-0.035001
ACACB	0.034599
MGLL	0.034402
OPTN	0.034381
CCDC83	0.034320
KIAA0513	0.034261
TYMS	-0.034246
TYMSOS	-0.034240
DOK7	0.034146
GDPD3	0.034043
NCAM2	0.033948
UPK3B	0.033768
LAMB1	-0.033692
STOM	0.033611
MAPK4	0.033547
BLACAT1	0.033544
CLIC3	0.033458
RERGL	-0.033275
FAM46C	0.033262
MAPK6	-0.033210
TMEM123	-0.033140
MYEOV	0.033136
KLF6	0.033087
KITLG	0.032944
MUC1	0.032494
TMEM79	0.032491
TGFB3	0.032358
S100A14	0.032281
UGT1A6	0.032274
FAM46B	0.031956
MGP	0.031763
CLIP4	0.031619
CELSR2	0.031569
WNT10B	-0.031473
BHLHE40	-0.031344
HIST1H2BG	0.030998
MCM3	-0.030989
MIR503HG	0.030952
E2F2	-0.030846
TMEM139	0.030799
MAST4	0.030550
LPIN1	0.030467
BCO1	0.030432
ZNF467	0.030423
LURAP1L	0.030421
TSPAN1	0.030416
BCYRN1	-0.030216
PRPS1	-0.030215
MVP	0.030206
CKMT1A	0.030162
SLC25A30	0.030162
S100A9	-0.030021
CMBL	0.030000
UPK2	0.029957
KIFC1	-0.029854
RMI2	-0.029829
VGLL1	-0.029819
NUCB2	0.029726
LEMD1	0.029603
ENTPD1	0.029600
CBX5	-0.029558
JAK2	0.029536
PLOD2	-0.029438
FXYD3	0.029396
SPPL2A	-0.029376
HPN	0.029335
NELL2	-0.029258
BNIPL	0.029241
HIST1H2BK	0.029198
KIAA1324L	0.029159
TLN2	0.029146
PLA2G4F	0.028981
KIF5C	-0.028965
ZNF91	-0.028886
HSD17B1	0.028850
ERC2	-0.028773
TUBB3	0.028753
CYSRT1	0.028737
DPY19L1	-0.028708
RHOB	0.028659
USP8	-0.028594
AFAP1L2	0.028586
PRKCA	-0.028565
TGFB2	-0.028506
MCM2	-0.028469
ST8SIA4	0.028436
PXMP4	0.028397
ATP1B1	-0.028339
ATAD2	-0.028319
LPAR5	0.028279
RASL11B	0.028261
AURKB	-0.028238
MYO5C	-0.028235
PROM2	0.028144
FLRT3	0.028034
ISG20	0.027970
CKB	0.027966
ZDHHC7	0.027939
CKMT1B	0.027936
CAPN5	0.027863
CDKN3	-0.027834
RAB32	0.027805
HMGB2	-0.027798
DEGS1	-0.027789
NCAPD2	-0.027728
CDCA5	-0.027715
MIR21	-0.027707
TRPM4	0.027604
UBE2E2	0.027579
LY6G6C	0.027543
TIMP2	0.027441
FAM3C	0.027420
CYB5R1	0.027362
PGM1	-0.027355
SPC24	-0.027327
BCL2	0.027318
TFAP2A	-0.027313
GPR115	0.027237
TFF1	-0.027209
XG	0.027112
EFNB2	0.027078
NFIA	0.027061
DTWD1	-0.027038
GRAMD2	0.026966
PSCA	0.026944
CCNB2	-0.026939
CGA	0.026923
RAD51AP1	-0.026914
LCP1	0.026811
CHEK1	-0.026801
CMYA5	0.026799
DDIAS	-0.026790
LINC00294	-0.026774
COLEC10	0.026734
MYB	-0.026685
CDT1	-0.026665
SSPO	0.026555
MELK	-0.026541
MB21D2	0.026472
PRC1	-0.026419
KYNU	0.026386
CDSN	0.026296
MND1	-0.026289
DRAM1	-0.026244
PARVA	0.026217
F2RL1	-0.026216
WFS1	0.026134
RHOD	0.026089
TCHHL1	0.026074
HIST1H2BD	0.026038
KCNK13	0.026034
PKMYT1	-0.026026
C15orf48	0.025957
IRX4	0.025909
CLDN23	0.025881
PRIM1	-0.025864
HIST1H1C	0.025861
PIK3C2B	0.025860
TEAD2	0.025846
HIST1H2BC	0.025766
TMCO3	0.025742
OXTR	0.025671
ZNF597	-0.025658
IGFL1	0.025636
CPE	0.025634
IRF9	0.025566
CYP1B1	-0.025566
ASPM	-0.025539
CDCA3	-0.025528
SAP30	-0.025502
PROM1	-0.025494
LYSMD2	-0.025494
MCM5	-0.025487
TESC	0.025486
FFAR2	0.025274
CAV1	-0.025273
IGFBP3	-0.025193
DLGAP5	-0.025187
MYO5A	-0.025143
HOPX	0.025030
TPBG	-0.024909
RFTN1	-0.024819
FANCI	-0.024778
PLEKHA6	0.024773
AMTN	0.024771
CASQ2	0.024741
KLF13	0.024725
NCAPG	-0.024700
KIF11	-0.024672
CENPK	-0.024658
HMOX1	0.024559
HIST1H4E	0.024518
RFC4	-0.024489
KRTCAP3	0.024487
A4GALT	0.024398
MCM6	-0.024332
CCNA2	-0.024296
RPRM	-0.024266
CRISPLD2	0.024236
NBEA	-0.024222
CROT	0.024217
ASF1B	-0.024207
PCGF5	-0.024201
CLDND2	-0.024196
C3orf52	0.024115
LYPD3	0.024061
IFITM1	0.024038
PKP2	-0.024032
NCOA7	0.024027
MCM10	-0.024014
CENPW	-0.024005
RRM2	-0.023997
HCAR1	-0.023981
MTHFD1	-0.023943
SALL4	0.023923
ATP6V0E2	0.023895
OIP5	-0.023890
KIF14	-0.023821
WNT3A	0.023804
S100A8	0.023798
PCGF6	-0.023752
LMO4	-0.023720
MATN3	0.023674
ST6GALNAC2	0.023657
HEY1	-0.023640
ANO6	0.023606
MMD	-0.023546
CDC42EP5	-0.023523
MT1F	-0.023522
EMP1	0.023520
CRIM1	0.023500
IGSF5	0.023456
SLC18B1	-0.023417
TACC3	-0.023389
PARM1	0.023377
TIFA	-0.023307
SLBP	-0.023242
IGFBP5	-0.023216
BRCA1	-0.023149
RAB30	-0.023102
LHFP	-0.023075
SSFA2	-0.023070
KCNJ13	0.023024
ACHE	0.022968
SPRY2	-0.022963
CDCA7L	-0.022928
EPHX2	0.022910
KLF4	0.022899
UBA5	-0.022897
FAM198B	0.022884
GSTK1	0.022827
VRK1	-0.022817
PLA2G4C	0.022790
MCM4	-0.022789
TMEM45B	-0.022768
TOP2A	-0.022767
MDC1	-0.022749
CITED2	-0.022747
PFKFB3	-0.022686
NUSAP1	-0.022669
LHFPL2	0.022642
SLURP1	0.022567
MAN1A1	-0.022555
TNFRSF11B	0.022544
CHST15	0.022521
ARID3A	0.022455
POLA2	-0.022401
BLM	-0.022395
DSCC1	-0.022375
PRCP	-0.022374
CAPN14	0.022285
CKS1B	-0.022263
TTK	-0.022238
GALNT12	-0.022220
ARSG	0.022202
ELF3	-0.022201
RPA3	-0.022184
PODXL2	0.022156
SDSL	0.022155
HIST1H2AE	0.022152
DDB2	-0.022152
THOC6	-0.022063
KRT16	0.022037
CENPM	-0.022005
TP53INP1	0.021995
HMCN1	-0.021825
NAV2	-0.021809
CAPN13	0.021790
FAM72D	-0.021781
GABRP	-0.021758
TST	0.021719
SLC16A9	-0.021684
SLC27A2	-0.021679
ALDH4A1	0.021620
GLDC	0.021586
ABCA4	-0.021550
CEMIP	-0.021533
KCNK2	-0.021496
SCCPDH	0.021488
LIG1	-0.021468
CYP4F11	0.021428
OAT	0.021424
SGOL1	-0.021413
TIGD2	-0.021389
GPR37	0.021354
NRM	-0.021347
C5	-0.021347
KIF15	-0.021337
DTL	-0.021331
AP4E1	-0.021313
APP	0.021306
PPIL1	-0.021295
SNORD12C	-0.021295
ASPH	-0.021261
EZR	0.021226
LXN	-0.021174
FZD4	0.021174
NXPH1	-0.021131
SNRPD3	-0.021082
TMEM132A	0.021078
TSPAN33	0.021073
RHOU	0.021026
KIF1A	0.020982
ALDOC	-0.020947
HENMT1	0.020929
LOC728323	0.020921
MAMDC2	0.020910
CALML5	0.020902
PCP4	0.020884
MYC	-0.020872
THBS1	0.020870
CLDN9	0.020852
CEP152	-0.020845
NADSYN1	0.020817
EVPL	0.020784
STX3	0.020747
CCDC103	0.020727
NR2F2	-0.020702
CTSH	0.020645
KRT80	0.020620
KCNK12	0.020613
PPP1R3C	0.020590
HIST1H3H	0.020526
GPSM2	-0.020517
NDC80	-0.020488
ZNF280D	-0.020486
KIF4A	-0.020459
CKAP2L	-0.020431
ZBED1	0.020402
ATOX1	0.020375
ACSL1	0.020370
NTN4	-0.020369
TFPI	-0.020339
FJX1	0.020331
C1QTNF6	0.020323
CRIP1	0.020311
HIST1H2BE	0.020300
LMO2	-0.020293
RORC	0.020291
UNC13D	0.020286
UBE2L6	0.020282
IL27RA	-0.020270
H1F0	-0.020261
CALHM2	0.020258
TBC1D31	-0.020256
BUB1	-0.020246
ITGB3BP	-0.020213
TIMP1	0.020199
PAWR	0.020196
ENO2	-0.020191
TRIM47	0.020170
NAMPT	0.020152
CHAF1B	-0.020132
KCNK15	0.020122
ZSWIM6	0.020111
SORT1	0.020101
ZKSCAN1	-0.019971
LIN7A	-0.019956
DHTKD1	-0.019950
TBC1D9	0.019943
SIRT4	0.019931
CARHSP1	-0.019924
ITPR3	-0.019880
SH3GL3	-0.019875
RNU1-3	0.019872
FOXM1	-0.019846
DUT	-0.019802
TMEM154	0.019786
PDE4D	-0.019748
CENPU	-0.019742
ANXA2	0.019650
STC2	-0.019616
SNORD13	0.019613
FAM111A	-0.019613
RAD54L	-0.019610
GDF15	-0.019600
RSL24D1	-0.019585
SIK1	0.019572
LRFN5	-0.019571
TUBB	-0.019504
ANXA9	0.019498
RAPGEF6	0.019474
EPAS1	-0.019471
TMEM125	0.019467