!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	4-Hydroxynonenal
!smiles	CCCCCC(C=CC=O)O
!pubchem_cid	5283344
!cell_type	RKO colorectal carcinoma cell line ( 6 Hours after exposure to 5uM)
!organism	human
!end_metadata
HMOX1	0.381860
TXNRD1	0.162345
SFN	0.124494
RPL34	-0.104380
MRPL33	0.094097
SOD1	0.091116
GCLM	0.086044
FTH1P5	0.074152
RPL9	0.068509
RAB13	0.066850
TUBB	-0.065969
LSM7	0.064785
SSR4	-0.063978
MT1H	-0.063435
HYOU1	0.063129
RPL14	0.062191
ATP5A1	0.061579
PRDX1	0.060830
HMGB2	0.059540
XPO1	0.059022
NQO1	0.058575
HMGA1	-0.057674
TALDO1	0.057336
UQCRH	0.056369
EIF4H	-0.056330
TUBB3	-0.054580
LSM1	0.054507
RPS11	-0.054381
RPL41	0.054166
DUSP5	-0.054022
NEDD8	0.053587
PTMA	-0.053423
NHP2	0.052941
RPL36	-0.052364
RPL23	-0.052102
HSPA4L	0.051885
IARS	0.051734
CTSL	0.051726
STIP1	0.051635
RPL24	0.051159
ABHD3	0.051038
TUBB4B	-0.050320
RPL23A	0.050155
HSPE1	0.049680
RPL36AL	0.049145
PUF60	-0.049070
TRIM28	-0.048933
S100A6	-0.048613
NDUFA1	0.048570
PLP2	0.048034
S100A16	-0.047748
POLR2H	0.047060
RPS8	0.046968
MGST1	0.046659
SLC16A14	0.046334
ANXA2P2	0.045664
SLC25A5	0.045305
RPL11	0.045077
RPL38	-0.044810
HSPA8	0.044655
EPHA2	-0.044478
ACTN4	-0.044411
RPL7A	0.044324
HSP90AA1	0.044316
RPL32	0.044243
OAZ1	0.043725
FBXL16	-0.043418
ACTG1	0.043315
COX1	0.043111
ND2	-0.042939
RPSA	0.042881
PROCR	-0.042631
EEF1B2	0.042490
UBC	0.042109
MT1F	-0.041850
UQCRB	0.041834
RNASEK	0.041814
PPME1	0.041784
CORO1C	0.041625
RPL35	0.041442
SNRPD3	0.041286
MALAT1	0.041284
VDAC3	0.041228
EIF6	-0.040984
KIAA0196	0.040797
RPS21	0.040735
RPS26	0.040517
NABP1	0.040515
RPS10	0.040299
SRFBP1	0.040281
SRSF2	-0.040231
NACAP1	-0.040156
SRM	-0.039931
SNRPF	0.039651
CWC15	0.039042
NDUFA13	-0.038505
FTL	0.038480
C2CD2	-0.038247
YTHDF2	-0.038095
SNHG6	0.038093
S100A11	-0.037972
ACVR1	0.037783
RPL12	0.037482
RPS7	0.037457
FAM35A	0.037429
PPP2R1A	-0.037364
SLC38A2	0.037312
MRPL51	0.037280
RPS25	0.037277
RPS17	0.037163
SLC25A3	-0.036905
RPIA	-0.036786
NME1	-0.036689
LMNB1	-0.036571
RPS13	0.036547
SPHK1	-0.036536
MAP2K1	0.036346
MAT2A	-0.036230
AHSA1	0.036055
LPCAT1	-0.035910
ARL6IP1	-0.035877
DNAJB11	0.035511
PSMD2	0.035451
SELT	-0.035192
RPL6	0.035028
BCL2A1	-0.034981
CCT3	0.034825
PKD1P1	-0.034572
ARRDC3	0.034393
MAP2K3	-0.034325
PRKRIR	-0.034324
ATP5I	-0.034323
EMC2	0.034169
FAM96A	0.034080
PDRG1	-0.034003
RSL24D1	0.033860
SLC7A11	0.033744
KLF10	-0.033478
RNASEH2A	-0.033369
TRAM1	0.033314
GLRX	0.033237
TUBA1C	0.033205
NEAT1	0.033026
ABL1	-0.033024
RPS3A	0.032841
MT1G	-0.032753
PGRMC1	0.032604
UBE2M	-0.032577
NPTN	0.032519
RPLP1	0.032386
PPIB	0.032302
UBE2C	-0.032197
CTGF	0.032192
ASUN	0.032103
PSMB7	0.032091
TPT1	0.031885
RPL30	-0.031821
CNBP	-0.031618
MICB	0.031616
MRPS30	0.031519
HMGB1	0.030942
TIMMDC1	0.030927
PARP4	0.030875
PHB2	0.030742
PA2G4	-0.030569
MRPL18	0.030290
PSMA1	0.030171
TOP1	-0.030153
BCAP31	0.030132
ERH	0.030125
CCNB1	-0.030103
HSP90AB1	0.030082
RPL26L1	-0.029967
OSTC	0.029885
DKC1	-0.029839
PLS3	0.029794
ATP6V1G1	-0.029736
MTERF3	0.029612
TMA7	-0.029512
NDFIP1	0.029505
GADD45A	-0.029482
RAB10	0.029377
BZW1	0.029343
ACSL3	0.029254
GPI	-0.029178
TMEM97	0.028954
SEC11A	0.028920
G0S2	-0.028884
CCDC86	-0.028769
CBR1	0.028746
MT1M	-0.028647
PABPN1	-0.028599
CDC37	-0.028566
HMGN4	0.028466
PRDX6	0.028458
HMGN2	0.028427
NOP2	-0.028417
SLC38A5	-0.028414
AP1S1	-0.028302
PFDN1	0.028236
CETN3	0.028097
SMAGP	-0.028063
PPP1R15A	0.028057
WDR82	-0.028030
EIF2S3	0.028017
DANCR	-0.027977
CCT2	0.027879
POMP	0.027795
SUMO2	0.027735
COX2	0.027651
SUGT1	0.027628
APOBEC3B	0.027606
ZDHHC6	0.027595
ARPC5L	-0.027577
CHCHD2	0.027547
UQCR10	0.027540
LAPTM4A	0.027443
PREPL	0.027091
RPL28	0.027081
ACOT9	0.027051
FAM216A	-0.027048
UFD1L	0.026994
BAG6	0.026954
MMADHC	0.026918
LINC00657	0.026861
RPS2	0.026848
IER2	0.026846
CCT4	0.026676
RAP1B	-0.026606
UQCRC1	-0.026499
FTH1	0.026415
TMEM165	0.026383
ABRACL	0.026333
GPX1	-0.026312
NDUFA4	0.026311
ATP5B	-0.026296
RNPS1	-0.026294
RPL13A	0.026181
DDX21	-0.026129
IER3	-0.026059
ZNF580	-0.026050
ARPC1A	-0.026045
SERPINH1	-0.025945
MAPK1IP1L	0.025865
BTBD1	0.025777
TMEM126A	0.025717
PPT1	0.025713
HIATL2	0.025596
HNRNPF	0.025562
RRP1B	-0.025549
SRSF6	-0.025508
RAB8A	0.025503
LRRC47	-0.025402
UBE2S	-0.025264
ANXA2	0.025210
USMG5	0.025203
COX3	0.025076
HDGFL1	0.025068
ANP32B	0.024993
NCKAP1	0.024969
UBB	0.024959
EMC10	-0.024946
GBE1	0.024922
MCM2	0.024848
SH3BGRL3	-0.024831
SNX3	0.024769
CACYBP	0.024623
WDR83OS	0.024593
SET	-0.024531
RPL7L1	0.024445
PRPF19	-0.024384
FKBP2	0.024347
MRPL3	-0.024345
CSRP1	-0.024227
BST2	0.024220
DPP9	0.024103
UCHL3	-0.024097
SLIRP	-0.024056
OXCT1	0.023996
PSMD14	0.023902
PCNA	-0.023828
NFKBIZ	0.023786
ACADVL	0.023773
OAT	0.023724
SLC44A2	0.023702
NACA	0.023698
ALAS1	0.023679
PPID	0.023558
RPS18	0.023545
TMEM258	0.023536
ELOF1	0.023501
COX6C	0.023457
ALDH2	-0.023380
SMTN	-0.023256
MIR22HG	0.023168
TVP23B	0.023133
GLO1	0.023015
ATP6V1F	0.023009
ATP6V1C1	0.022990
PRIM1	0.022963
SLC52A2	-0.022903
COLGALT1	-0.022838
TRMT10C	-0.022830
DPM1	0.022813
PSMC6	0.022811
MRPL13	0.022780
ACTB	0.022779
RBMXL1	0.022747
SNRNP40	-0.022722
MIF	0.022719
PITPNB	-0.022662
FAM206A	0.022640
IRAK1	-0.022504
VBP1	0.022496
DTL	0.022491
ODC1	0.022450
STAU1	-0.022358
BAK1	-0.022336
TIPARP	0.022258
MGEA5	0.022245
RPL21	0.022211
ACOT13	-0.022080
COX7C	0.022010
GABARAPL2	0.021954
RPL4	0.021948
LDHA	0.021907
RPS23	-0.021898
RFK	0.021775
KDELC2	-0.021719
C12orf5	-0.021713
FRG1	0.021657
RHOF	-0.021550
FAM210B	-0.021504
CHMP5	0.021475
NPIPA1	-0.021464
GTPBP3	0.021417
ERO1L	0.021390
SLC3A2	0.021354
UFC1	-0.021330
FUCA2	0.021316
ERLIN1	0.021315
NARS	0.021309
GHITM	0.021306
DPY30	0.021288
CTCF	-0.021275
LYAR	-0.021269
BET1	0.021168
MPST	-0.021123
SNRPA	-0.021113
RUSC2	0.021113
FZD6	0.021112
ARHGDIA	-0.021096
ZNF593	-0.021051
SH2B3	-0.021045
MAT2B	0.021031
LINC01504	-0.020968
PRC1	-0.020934
PTPLAD1	0.020901
ZYX	-0.020898
TMX1	0.020845
LOC100134445	0.020831
COLCA1	-0.020754
GPR108	0.020684
TKT	-0.020533
UQCRQ	-0.020516
FAM171A1	-0.020495
NUDT19	-0.020476
IFI16	0.020473
TMEM14B	0.020455
DNAJB1	-0.020450
AP3S1	0.020430
WBP5	0.020376
IRF2BPL	0.020326
TPX2	-0.020315
POLR2F	0.020265
URM1	0.020204
PHB	0.020200
CPOX	0.020165
HJURP	-0.020160
SURF4	0.020156
SNHG1	0.020126
NOLC1	-0.020113
HNRNPA2B1	0.020082
RHOC	-0.020028
C1orf52	-0.019998
ADORA2B	-0.019973
CIAO1	-0.019966
TOMM22	-0.019931
TMED2	0.019926
SFTA1P	0.019904
PFKM	0.019873
HSPA4	0.019849
RNF11	0.019818
GLA	0.019783
MRPL43	-0.019762
ARL6IP4	-0.019757
SRXN1	0.019718
TYW3	0.019675
GLIPR1	0.019672
SLBP	0.019665
GAPDH	0.019643
SEC61G	0.019598
CTBP1	-0.019589
GPX4	-0.019582
ISCU	0.019577
EIF4A1	0.019559
HOXC6	0.019554
TBK1	-0.019526
ALDOA	0.019525
BCAS2	-0.019523
GPX8	0.019512
HMGN1	0.019512
R3HDM4	-0.019509
NAA50	0.019474
FAM188A	0.019459
ATP5J2	0.019450
SPCS1	0.019432
ID3	0.019423
STUB1	-0.019383
MEPCE	-0.019331
POLR2E	-0.019302
MRPS2	-0.019294
FKBP11	0.019254
C12orf45	0.019252
PPAN	-0.019228
TRMT6	-0.019226
STX17-AS1	-0.019206
SRP9	0.019128
USP1	0.019115
PABPC3	-0.019078
TATDN1	0.019054
OTUD6B	0.019039
GEMIN5	-0.019019
SLC35F2	-0.019002
NANP	0.018997
STAT3	0.018949
EEF1D	0.018945
NGFRAP1	-0.018944
PPP1R8	-0.018936
CALR	-0.018932
HNRNPH1	0.018905
LMNB2	-0.018897
ACTR3	0.018863
GTF2H2	0.018825
BLVRB	0.018778
WDR43	-0.018683
NEU1	0.018672
HK2	0.018629
POLR2L	-0.018607
ASH2L	-0.018566
TTYH3	-0.018562
DEK	0.018558
HSPB1	0.018558
UNG	0.018530
DHX36	0.018527
KARS	0.018490
BLOC1S2	0.018488
XPC	0.018464
LBR	0.018451
ANLN	0.018451
RAD51AP1	0.018441
CDC42SE1	-0.018390
SNRPB	-0.018341
VPS26A	0.018312
SLC5A6	-0.018308
LDHB	0.018299
MNX1	-0.018298
RAB5C	0.018280
FAM169A	0.018276
NPDC1	-0.018272
MSMO1	0.018254
HIGD2A	0.018220
CYC1	0.018219
HNRNPUL1	-0.018218
CCNE2	0.018187
UBQLN1	0.018170
NDUFB4	0.018114
CDCA4	0.018105
TEX2	-0.018060
GNB2	-0.018042
NDUFA3	-0.018038
RFC4	0.018031
PSME2	0.017962
CLCN3	0.017954
CLN5	0.017943
NQO2	0.017934
RPLP0	0.017922
UBL5	0.017922
PSMA2	0.017920
DTD1	-0.017857
RPL8	0.017798
C19orf48	0.017744
OR7E104P	-0.017641
RTN3	0.017637
VKORC1	0.017630
RFNG	-0.017613
GDI2	0.017582
RYBP	0.017576
NDUFA9	0.017556
ATP6V0B	0.017525