!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	Uterus - single injection of 400 ug/kg - 8 Hours after treatment
!organism	mouse
!end_metadata
RPS19	0.183916
PLET1	0.171429
CSTB	0.138447
LAPTM4A	0.135197
IER3	0.128268
LTBP4	-0.126343
DSTN	0.122232
COL1A1	-0.121790
DYNLL1	0.107338
HIF1A	0.102247
JUND	0.101220
HSPA5	0.100363
DIO2	0.099059
ACTG1	0.098943
ANXA2	0.096899
GADD45G	0.096805
TAGLN	0.092704
CHD4	0.090672
ERRFI1	0.089770
GAS6	0.087821
MYH11	-0.086951
ENG	0.083376
HSP90B1	0.083015
BCAT1	0.082429
RPS26	0.080971
COL6A2	-0.079589
LSP1	-0.076221
ERH	0.075980
CFL1	-0.075100
KCTD12	-0.074467
LUM	-0.073036
ID2	-0.069153
PABPC1	0.068359
DMPK	-0.065466
ISYNA1	0.065265
CEBPB	0.064592
SOX18	0.063891
TUBA1B	-0.063392
EMP1	0.063155
SERP1	0.063150
FSCN1	-0.062834
SURF4	0.062669
MDH2	0.062254
APCDD1	-0.062131
MANF	0.061903
PPIA	0.061721
WDR6	-0.060953
NHP2	0.060348
ISLR	-0.059497
PTOV1	-0.059010
KDELR1	-0.057273
HSD17B11	0.056045
AES	-0.055310
KRT7	0.054249
SOCS1	0.054043
GNG5	0.053985
WDR77	0.053395
TWIST2	0.053373
MORF4L2	0.053322
LAMC2	0.053150
SPARC	-0.052938
HSPD1	0.052923
ALDOA	0.052664
CRTAP	-0.051907
TUBB	-0.051553
SLC35B1	0.051408
PLP2	-0.050966
GJA1	0.050344
SMTN	-0.049647
CCT7	0.049567
COL5A2	-0.049305
FMO1	-0.049261
GLRX3	0.049105
RABAC1	-0.048864
MYH9	0.048180
ANAPC5	-0.048058
RPS15A	0.047276
RPL7	0.047158
HSPA8	0.047157
SELT	0.047097
RPS12	0.046781
TRAM1	0.046726
PADI2	0.046620
RBM3	0.046265
ANXA3	0.046079
PTPN1	0.045972
RAMP3	0.045941
MDK	-0.045697
C11orf31	-0.045545
COL1A2	-0.045424
STMN1	-0.045329
NPNT	-0.045271
MRFAP1	0.045044
TUBA1A	-0.044942
RNF10	0.044475
NFIX	-0.044053
ARPC2	0.042810
GNB2L1	-0.042777
CNN1	0.042484
RAC1	0.042383
C12orf57	-0.042246
SSR3	0.042082
NPM1	0.041831
H2AFV	-0.041744
TUBB6	0.041517
RPL5	0.041259
PADI1	0.041232
CA2	0.041230
C3	0.040800
TUBA1C	-0.040784
TKT	-0.040757
CDK2AP1	-0.040706
ANXA6	-0.040478
ATP6V0C	0.040358
MFAP2	-0.040058
ACAA2	-0.039814
S100A10	-0.039718
RPLP0	0.039670
MFGE8	0.039623
MYADM	0.039542
RPS3	-0.039489
HOXA11	-0.039307
ZBTB20	-0.039297
INPPL1	-0.039239
COL15A1	-0.039058
IGFBP6	0.038830
CSNK1G2	-0.038685
TIMM13	-0.038635
BGN	-0.038592
SLC25A39	0.038174
PRMT1	0.038129
RASD1	0.038064
HTRA1	0.038036
EEF2	-0.037981
DEK	-0.037633
PLK2	0.037248
PLTP	-0.037037
MIDN	0.036927
GORASP2	0.036368
SUMO3	0.036323
SOX17	-0.036300
ARF5	-0.036274
CCNB2	-0.036238
OSTC	0.036184
ARL2BP	-0.036078
SRSF6	0.035923
CTSB	0.035803
BZW2	0.035717
COL4A1	0.035695
PSMA3	0.035307
PKM	-0.035299
HNRNPH1	0.035260
G6PD	0.035242
LRRC59	0.035127
AKR1A1	-0.035078
MORF4L1	0.034959
NREP	-0.034704
F3	0.034665
PDIA3	0.034625
FBLN2	0.034620
GNG12	0.034616
TIPARP	0.034580
UBE2R2	0.034449
MARVELD1	-0.034244
SPCS2	0.034067
PSD	-0.034022
MGP	-0.034013
IFITM3	-0.033922
TRIM28	-0.033556
COL6A1	0.033382
GAS1	-0.033297
BPIFB1	-0.033272
NOP10	-0.033262
LPHN1	-0.033174
PPM1G	-0.033118
RPL6	0.032926
SFRP2	-0.032874
TIMP3	0.032870
PLK3	0.032832
PCOLCE	-0.032754
CDC20	-0.032589
RNASEK	-0.032423
RPN2	0.032392
COX6A1	0.032350
VKORC1	-0.032102
HSP90AA1	0.032038
SLC25A4	0.032003
H1F0	-0.031917
COL4A2	0.031768
RPS27A	-0.031708
IGFBP3	-0.031595
DPT	-0.031500
POLR2M	-0.031318
TMOD3	0.031269
SNX3	0.031153
ANGPTL2	0.031135
EIF2S3	0.031084
TAGLN2	-0.030979
WFDC2	-0.030961
XBP1	0.030706
SERINC3	-0.030673
CDC37	-0.030528
LCN2	0.030417
MAGED2	-0.030369
SCARB1	-0.030327
GNB2	-0.030154
RRAGA	-0.030015
ELF3	0.029976
ACKR3	0.029844
LBP	-0.029798
SCX	-0.029730
U2AF2	0.029549
SMOC1	0.029458
ARHGEF25	-0.029447
ACTN4	0.029431
PCNA	-0.029361
BRI3	-0.029330
NT5DC2	-0.029309
DCAF12	0.029203
HSPA9	0.029187
EID1	-0.029021
SEC61A1	0.029002
UGDH	0.028911
PSMA6	0.028512
PDIA4	0.028506
ALDH2	-0.028482
THY1	-0.028363
RPS24	0.028094
TCF19	-0.028016
CALB1	-0.027963
FZD2	-0.027939
PDIA6	0.027892
UHRF1	-0.027850
MTCH2	0.027847
NDP	-0.027838
TPI1	-0.027758
PENK	-0.027719
PHPT1	-0.027709
MSN	0.027680
ARF4	0.027671
ITGB1	0.027523
HINT1	-0.027451
LDHA	-0.027441
SPARCL1	-0.027401
IER2	0.027280
CLEC11A	-0.027126
COL3A1	-0.026905
RPS10	0.026891
SOCS2	0.026882
OGN	0.026801
TMED10	0.026691
EIF4A2	-0.026689
WBP1	-0.026652
DCN	-0.026601
UQCRC2	0.026389
CRIP1	-0.026373
PRNP	0.026242
DYNLRB1	0.026226
SOX4	-0.026169
H19	-0.026168
IGF1	0.025980
SEC61B	0.025959
RPL18	0.025925
PKDCC	-0.025913
PSAP	-0.025799
CYB5A	0.025695
CEBPD	0.025645
MARCKSL1	-0.025548
PNRC2	-0.025443
LMNB1	-0.025435
TCF12	-0.025401
ALPL	0.025321
HSP90AB1	0.025311
SFT2D1	0.025214
CRELD2	0.025191
CST3	-0.025185
ERGIC3	-0.025165
WLS	-0.025120
SHFM1	-0.024777
GSN	0.024771
IGSF8	-0.024676
STK40	0.024675
HSPH1	0.024654
MCM7	-0.024633
FKBP11	0.024565
HADH	-0.024560
NSA2	-0.024542
SLC3A2	0.024415
NFIC	-0.024314
TMED7	0.024308
BRK1	0.024229
MPRIP	-0.024212
PSMB3	0.024211
LITAF	0.024195
SPOCK2	-0.024189
RERE	-0.024182
CYC1	0.024125
TSC22D1	-0.024096
HK1	0.024091
PSMD12	0.023989
MAP1LC3B	-0.023623
GSK3A	0.023602
EIF3G	-0.023600
ANKRD46	0.023571
NAPA	0.023542
CCT4	0.023531
CLPTM1L	0.023505
FAM134A	-0.023471
IDH2	-0.023424
PPP1R14B	0.023422
HSPG2	-0.023390
H2AFX	-0.023362
EZR	0.023282
FOS	0.023282
TSR1	0.023264
GLTP	0.023227
RBM17	0.023196
SERPING1	-0.023123
RPA1	-0.022965
NDUFV1	-0.022923
ACTN1	0.022893
SMC4	-0.022892
PGRMC1	-0.022825
YBX1	-0.022806
ISOC1	0.022628
MYH14	0.022622
ACTA2	0.022612
CLTC	0.022607
UBC	-0.022574
CTPS1	0.022535
PRKACA	-0.022501
PSMA2	0.022430
HSD17B10	-0.022418
CPE	-0.022377
MOGS	0.022315
CIC	-0.022296
SPSB1	0.022293
YWHAG	0.022254
NR1D2	-0.022233
PERP	0.022229
POSTN	-0.022193
ST5	-0.022178
APP	0.022172
TGFB1I1	-0.022161
MRC2	-0.022052
PCP4	-0.022038
CSRP1	0.021977
TXNDC5	0.021943
SNAI2	0.021842
FPGS	0.021841
PRKAR1A	0.021820
SERPINF1	-0.021740
LMNA	-0.021678
APOA1BP	-0.021624
PSMD1	0.021549
VAPA	0.021538
UQCR11	-0.021522
BTG2	0.021492
FKBP8	-0.021481
EIF3C	-0.021395
ITM2C	0.021378
SNX9	0.021358
KIAA0020	0.021318
DNAJC9	-0.021241
MAF1	-0.021207
PAPSS1	-0.021154
CNN3	-0.021118
DNAJB11	0.021104
ALAD	0.021095
BAG6	-0.021092
UQCRHL	0.021066
ARPC1B	0.020976
SRP9	0.020972
UBA5	0.020934
TSSC4	-0.020870
CCNA2	-0.020799
FAM195B	0.020790
TIMM17A	0.020725
STAT5A	0.020712
KIF22	-0.020706
TMPO	-0.020681
TM9SF1	0.020579
THBS3	-0.020565
BOK	-0.020533
COX7A2	-0.020521
DCTN1	-0.020520
POLR2L	0.020512
CAPN1	-0.020460
SEC61G	0.020419
PTP4A1	0.020388
TGFBI	-0.020368
C5orf15	-0.020365
RNF167	-0.020362
ID4	-0.020306
RAD21	-0.020278
RNASE4	-0.020223
CDK1	-0.020210
RBBP7	0.020195
RABGGTB	0.020160
EHMT2	-0.020108
IGFBP4	-0.020106
SGK1	0.020066
RUVBL2	-0.020022
RPS17	-0.019996
UBA1	0.019958
VPS72	-0.019880
DAP	-0.019822
SUCLG2	-0.019791
C17orf62	0.019788
COL6A3	0.019706
YWHAZ	-0.019696
ACTB	-0.019677
COX17	0.019671
SRSF2	0.019657
AIFM1	0.019638
NAB2	0.019627
SESN1	-0.019627
GTF2I	-0.019602
TACSTD2	0.019566
BROX	-0.019548
SSR2	0.019531
C19orf43	-0.019514
PSMB6	0.019497
A2M	-0.019442
GPC3	-0.019428
HN1	-0.019337
FKBP2	0.019274
MBNL1	0.019211
RBP1	-0.019170
KRT8	0.019169
GLTSCR2	-0.019164
PFKL	-0.019149
RIN2	-0.019135
PJA1	0.019129
CEBPA	-0.019119
SEPT2	0.019060
ARPC3	0.019058
FOXM1	-0.019057
PPAP2B	0.019052
RPS7	-0.018940
TGIF1	-0.018931
PLEKHB2	0.018897
PDCD4	-0.018814
LSM2	-0.018721
RPL27A	-0.018717
AQP1	-0.018706
RARS	0.018686
DDB1	0.018608
POLD2	-0.018563
MYL12A	0.018514
PPDPF	-0.018507
FLNB	0.018489
TMEM109	-0.018482
AGRN	-0.018432
ADD1	-0.018415
BZW1	0.018338
ADH1C	0.018274
TMEM165	-0.018236
PTK7	-0.018232
COL18A1	-0.018197
TRPC4AP	0.018162
ACAA1	-0.018113
RELA	-0.018102
RANBP1	0.018101
GSPT1	0.018079
FBL	-0.018078
VCP	0.018063
SYPL1	0.018045
PGK1	0.018041
S100A6	-0.018029
EIF3B	0.018017
RPL13	-0.017952
PALM	-0.017929
NOP16	0.017928
ZFPM1	-0.017857
NOP2	0.017849
TOP2A	-0.017846
NDE1	-0.017844
RAD51AP1	-0.017833
CYFIP1	0.017828
FTO	-0.017814
CD63	0.017767
PARD3	0.017754
KLF4	0.017702
TUBB4A	-0.017673
ACTA1	0.017662
PCID2	0.017646
PABPN1	-0.017636
SLC6A9	-0.017635
CKS1B	-0.017633
CD93	0.017631
MPP1	-0.017603
ALAS1	0.017600
MRPL52	0.017590
RAMP1	-0.017582
CNIH1	0.017566
JAGN1	0.017562
CACNB3	-0.017560
EIF3J	0.017558
RRS1	0.017453