!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Bleomycin
!smiles	CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O
!drugbank_id	DB00290
!pubchem_cid	5360373
!cell_type	Lung (Fra-1 deficient mutants)
!organism	mouse
!end_metadata
SPRR1A	0.113053
SPP1	0.090138
CCL17	0.082621
TIMP1	0.079681
MMP12	0.063036
CLDN4	0.060965
CXCL10	0.060059
TNIP3	0.058674
S100G	-0.057766
CHL1	0.056889
DCSTAMP	0.054576
IGFBP3	-0.054459
C3AR1	0.053759
TNC	0.052886
SFRP1	0.049240
SFN	0.048825
CCL13	0.048259
THBS1	0.046852
LIF	0.046483
PIGR	-0.046163
CLEC6A	0.046048
MS4A6A	0.045981
P4HA3	0.045790
CDKN1A	0.045576
CYP1A1	-0.045341
GPNMB	0.044888
MSR1	0.044731
GDF15	0.044650
TGM1	0.044442
ECM2	-0.044216
CYP7B1	0.043927
NXPE4	0.043926
FN1	0.043630
VCAN	0.043329
ZNF559-ZNF177	-0.042978
TFF2	-0.042882
PSRC1	0.041659
GATM	0.041036
S100A9	-0.040458
C1QA	0.040374
VSIG4	0.040253
DISP2	0.039668
GMNC	-0.039484
CCL22	0.039360
CCR5	0.038993
PGLYRP1	-0.038580
C1QB	0.038458
PIANP	0.037147
ACOXL	-0.036289
TRIM29	0.036249
CLEC5A	0.036114
C1QC	0.035873
NPPA	0.035705
CFTR	-0.035633
S100A4	0.035517
ANKRD1	0.035504
IRF7	0.035338
SCN3A	-0.035001
EGR1	0.034740
OVOS2	-0.034250
S100A8	-0.034245
SLC4A11	0.034214
CTSE	-0.033820
GJB4	0.033703
CCDC129	-0.033627
CH25H	0.033451
NKX2-8	0.033161
TM4SF19	0.033137
C11orf82	0.032685
KIAA0408	-0.032650
RGS16	0.032637
PSCA	0.032531
CTSK	0.032502
FAM110D	0.032461
CXCR2	-0.032419
CPM	-0.032137
CYR61	0.031968
FABP1	-0.031799
ATF3	0.031726
LY6G6C	0.031704
BRINP1	0.031559
FCGR2B	0.031542
GPR114	0.031472
MS4A7	0.031109
GTSE1	0.030957
RTKN2	-0.030934
SERPINE1	0.030724
HSD11B2	0.030462
TREM2	0.030423
C8orf4	-0.030314
CHAD	-0.029996
CORO2A	0.029973
HAL	0.029957
SESN2	0.029920
PPP1R13L	0.029902
SLC26A4	0.029836
TBC1D2	0.029830
TSPAN4	0.029795
TFPI2	0.029765
C14orf159	0.029743
ATP6V1C2	-0.029567
SELP	0.029519
PHLDA3	0.029469
NXPE2	0.029425
ASF1B	0.029407
LOX	0.029355
FSCN1	0.029303
AKR1B10	0.029221
E2F8	0.029206
AREG	0.029165
SAA2-SAA4	0.029155
REPS2	-0.029075
CST8	-0.028981
SOCS3	0.028977
TGFBI	0.028869
HCN1	0.028861
TAS2R60	-0.028797
ADRA1A	-0.028716
ZBP1	0.028643
BDKRB1	0.028604
PLA2G2D	-0.028590
CCR2	0.028498
RASGRP3	-0.028457
MS4A1	-0.028390
PDE8B	-0.028220
RAB6B	-0.028220
MEST	0.028220
CHSY3	0.028120
OCIAD2	-0.028116
ZNF385A	0.028068
PLAU	0.028065
TNFSF18	0.028049
CCNB2	0.027983
ITGAE	0.027965
PRR11	0.027952
CCNG1	0.027932
ANLN	0.027769
IGF1	0.027688
CD209	0.027585
FCAMR	-0.027419
EMCN	-0.027394
CHRDL1	-0.027290
APOBEC1	0.027247
COLQ	-0.027245
CCNA2	0.027232
FAIM2	-0.027174
SLC7A5	0.027138
MET	-0.027135
SYT12	0.027135
AAAS	0.027043
PTGFR	-0.026985
CKAP2	0.026974
MCM6	0.026933
KCNA2	-0.026836
PLK1	0.026576
CPXM1	0.026530
FGG	0.026506
APLNR	-0.026443
LIPF	0.026420
FGF2	0.026249
ITGA8	-0.026245
HMGCS2	-0.026182
MYH7	-0.026174
COX6B2	0.026128
VEPH1	-0.026043
ANGPTL7	0.026043
FGFR4	-0.026037
PCOLCE2	-0.025960
GLP1R	-0.025908
PLA2G1B	-0.025880
GP2	-0.025878
GPR176	0.025874
KYNU	0.025847
GADD45G	0.025808
CFP	0.025784
P2RY6	0.025748
VIPR2	-0.025726
TNFRSF12A	0.025630
SCARB1	0.025546
FGFR2	-0.025533
SYTL5	0.025519
PLD4	0.025465
PRRG4	0.025386
SHC4	0.025318
LGALS3	0.025287
NRN1	-0.025267
ATG9B	0.025252
HILPDA	-0.025249
CYTH4	0.025234
LAMA3	-0.025181
FCGR1A	0.025141
CTSS	0.025074
SERPINA3	0.025073
SERPINB10	-0.025035
CDH16	-0.024986
SLITRK6	-0.024977
C10orf10	-0.024961
IL36G	-0.024957
SELL	-0.024954
GULP1	-0.024681
RMDN2	-0.024680
SLC19A2	0.024646
RASGEF1B	-0.024605
ZRANB3	0.024594
CNGA2	0.024581
MAMDC2	-0.024567
KLRG1	0.024505
BEX4	-0.024440
GCLC	0.024408
LRAT	-0.024392
ARHGAP11A	0.024349
RNF144A	-0.024259
TUBB6	0.024246
IQGAP3	0.024205
C1QTNF2	-0.024199
MASTL	0.024189
TM4SF5	0.024164
PODN	0.024142
BCL3	0.024127
PIDD	0.024125
TMEM45B	-0.024119
SLC39A2	0.024107
POF1B	-0.024100
GDA	0.024096
ENC1	0.024080
GNA15	0.024061
MAP3K6	0.024050
NPR3	-0.024022
ITGAX	0.023992
BMPR1B	-0.023950
CENPM	0.023942
CD68	0.023922
EREG	0.023907
KIAA1524	0.023800
GLB1L3	-0.023755
SIGLEC1	0.023744
NNMT	0.023740
CENPN	0.023737
SLCO4C1	-0.023688
MMP19	0.023663
FCRL1	-0.023630
SLC4A5	-0.023543
SLAMF9	0.023521
LY86	0.023501
SHISA4	0.023491
KRT18	0.023470
HYKK	-0.023453
ZBTB16	0.023387
CHRNA7	0.023366
VNN1	-0.023352
MARCO	0.023341
KCNJ2	-0.023336
RAB3IL1	0.023308
OGN	-0.023296
EBF1	-0.023279
ST6GALNAC3	-0.023277
HBEGF	0.023223
CTSD	0.023216
SNAI1	0.023164
CDK1	0.023162
TCF19	0.023150
PHLDA1	0.023144
PLCE1	-0.023133
CCNB1	0.023034
CKAP2L	0.023028
EDNRB	-0.022998
SLC39A14	0.022972
FAM124B	-0.022951
F7	0.022950
LGALS3BP	0.022944
ABLIM3	-0.022937
LRG1	0.022930
CCR4	0.022907
CCL28	-0.022864
CCND1	0.022848
AURKB	0.022779
FETUB	0.022769
MS4A8	0.022737
MKI67	0.022682
SLC39A8	-0.022662
ALAS2	-0.022643
RGS13	-0.022624
AR	-0.022599
CCR8	0.022577
PPP1R14C	-0.022495
IL2RA	0.022488
TFAP2A	0.022484
SEMA3A	-0.022437
KCNK2	-0.022419
GRIA1	-0.022419
CEP55	0.022396
NLGN2	0.022374
ARHGAP20	0.022361
PTGER4	0.022312
SLC15A2	-0.022265
MTHFD2	0.022240
LTBP2	0.022219
BANK1	-0.022210
VTN	-0.022177
OAS2	0.022167
LIMCH1	-0.022123
KLF15	-0.022097
TPPP3	-0.022078
GRHL3	0.022050
NUF2	0.022049
CLCN5	0.022041
RAP2B	0.022037
CRY1	0.022003
EGR2	0.021962
KIF18B	0.021904
PHACTR1	-0.021902
MCC	-0.021876
COL1A1	0.021847
PLA1A	0.021840
CCNF	0.021817
ZMAT3	0.021781
CR2	-0.021720
IFIT1B	0.021698
OR5V1	0.021677
ITIH4	-0.021669
MMP14	0.021668
PTGS1	0.021668
MAFB	0.021653
SBNO2	0.021634
BHLHE40	0.021632
CNKSR2	-0.021628
TARM1	0.021573
FBLIM1	0.021541
KLHDC8A	0.021522
GIMAP4	-0.021478
LAIR1	0.021473
CDA	0.021425
ECT2	0.021359
PON1	-0.021324
CCL3L3	0.021309
HMMR	0.021284
CCRL2	-0.021274
INF2	0.021263
CLEC10A	0.021209
DDIT4L	0.021187
GFPT2	0.021180
OAS1	0.021165
KIF22	0.021124
B3GNT3	0.021119
CTTNBP2	-0.021107
FLNC	0.021098
WISP1	0.021087
HHIP	-0.021079
ASPN	-0.021070
SPECC1L	-0.021038
SLC13A2	-0.021031
TTK	0.021008
CAPN11	0.020990
PKD2L1	0.020979
IRX2	-0.020977
GEN1	0.020967
CSF2RB	0.020962
SERPINE2	0.020941
CLEC7A	0.020926
ATP6V0D2	0.020912
LAMA1	0.020883
TPX2	0.020864
SSH2	-0.020839
SPTA1	-0.020790
CCDC80	0.020764
SLC38A4	-0.020754
SNCG	0.020718
NCR1	-0.020710
MUC5B	-0.020701
KRT8	0.020697
DSCC1	0.020670
OR8J3	0.020663
LHFPL2	0.020662
BPIFA1	0.020659
RRM2	0.020651
TCEAL1	-0.020621
SLC7A8	0.020605
SLC15A1	0.020603
CLEC14A	-0.020583
CCDC85A	-0.020569
XCR1	0.020535
OR6S1	-0.020494
HAS2	0.020493
SLC19A3	-0.020484
BCAN	-0.020474
EDIL3	-0.020469
KIF2C	0.020460
IGSF9B	0.020459
FCGR2A	0.020455
DAPK2	-0.020434
NPW	-0.020411
MYCT1	-0.020390
KCNJ13	-0.020389
AMPH	-0.020380
ADAMTS4	0.020379
LILRB4	0.020377
EFEMP2	0.020361
CCNE1	0.020345
CXCL17	0.020345
SLC37A2	0.020342
DIAPH3	0.020320
PLA2G4C	0.020317
GPR141	-0.020312
NR3C2	-0.020294
BAMBI	-0.020287
EMILIN1	0.020287
PMEPA1	0.020278
B3GALT2	-0.020258
SLC16A11	-0.020229
APLN	-0.020210
CENPE	0.020204
AKAP5	-0.020203
RACGAP1	0.020138
SLC38A5	-0.020138
TBC1D24	0.020117
EDA2R	0.020117
BIRC5	0.020104
SEMA6B	0.020101
NDC80	0.020094
NCAPG2	0.020084
CACNB3	0.020083
CALCB	0.020067
PTGIR	0.020063
CPT1C	0.020062
CD80	0.020049
ARL11	0.020040
MS4A4A	0.020039
CXCL14	0.020036
SDPR	-0.020025
CTPS1	0.020019
HOPX	-0.019953
ETS2	-0.019952
ALDH6A1	-0.019938
WNT7B	0.019912
S100A14	0.019904
TMEFF2	-0.019897
NR4A3	0.019895
CDKL5	-0.019894
CDCA8	0.019887
NPHS2	-0.019873
ITGAM	0.019871
ATP8B1	0.019865
GID4	-0.019852
ZFP69	-0.019820
SULF2	0.019811
OLR1	0.019798
COLGALT2	-0.019773
KIF23	0.019742
USP18	0.019732
NEK6	0.019719
CHEK1	0.019717
FANCA	0.019702
GNG11	-0.019690
TMEM173	0.019683
COL3A1	0.019674
KIAA1324	-0.019651
PLXNC1	0.019629
MYO6	-0.019620
CNR2	-0.019615
CLU	0.019612
SCN7A	-0.019589
ENKUR	-0.019588
GAS7	0.019579
EMR1	0.019542
PPP1R1B	-0.019521
PROCR	0.019517
VWF	0.019492
CASC4	-0.019468
ZNF14	-0.019467
BMP2	-0.019453
COL5A2	0.019426
PTPRK	-0.019423
CDO1	-0.019423
MAOB	-0.019422
B4GALT5	0.019417
SERPINB2	0.019415
TSHR	0.019405
TNFRSF18	0.019397
DACH1	-0.019367
E2F7	0.019354
DTL	0.019311
LRRC32	0.019280
AK1	0.019275
DAPL1	-0.019245
GUCY1B3	-0.019233
RIN1	0.019228
SH2B2	0.019219
XPNPEP2	-0.019203
SNAI2	-0.019199
BMP6	-0.019197
ESCO2	0.019164
TMEM132D	-0.019161
SYDE2	-0.019159
FBXO30	-0.019154
HMOX1	0.019152
ITIH5	-0.019148
CTSZ	0.019143
SCN1B	0.019129
FIBIN	-0.019106
FAM83H	0.019072