!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Streptozocin
!smiles	CN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O
!drugbank_id	DB00428
!pubchem_cid	29327
!cell_type	Liver tissue
!organism	mouse
!end_metadata
FMO3	0.154591
CDKN1A	0.149600
CYP2B6	0.143626
LY6D	0.114609
LCN2	0.094546
C11orf82	0.090893
EDA2R	0.090088
SULT1E1	0.087632
CSAD	-0.084467
SLC34A2	0.084442
TUBA8	0.083232
PHLDA3	0.082418
NPAS2	0.077396
MYBL1	0.077071
GCK	-0.074613
ELOVL3	-0.073737
ACMSD	0.072215
SAA1	0.068238
GRIA3	0.066877
DIO1	-0.065237
GADD45G	0.063629
MOXD1	-0.062435
AACS	-0.061097
CIDEC	-0.059277
G0S2	-0.058901
NXPE2	-0.058300
PLK2	0.057943
FABP5	-0.057344
AQP8	-0.055574
USP18	0.055389
BCL6	-0.054650
FABP2	-0.053394
SLC10A2	-0.052136
IGFBP1	0.051904
C5orf42	0.051546
CYP4A11	0.051118
SULF2	0.050320
DMBT1	-0.049838
MDM2	0.049806
H19	0.049790
NQO1	0.049369
PLS1	0.048494
TMEM43	0.048055
GDF15	0.047647
THRSP	-0.047129
TP53INP1	0.046973
MYC	0.046667
ID3	0.045535
GPAM	-0.045434
GPR110	-0.045323
MBL2	0.045277
PHLDA1	0.044596
ARNTL	0.044317
MMD2	0.044234
POLK	0.043483
MYL1	-0.043451
CYP17A1	0.042585
CCNG1	0.042383
HAO1	-0.042376
INHBE	-0.042342
OSGIN1	0.042061
SLC16A5	0.041826
ARRDC3	-0.041421
HES6	-0.041120
CCND1	0.040905
CISH	0.040253
BTG2	0.039964
TNFRSF10A	0.039854
CYP26A1	0.039689
PEX11A	-0.039433
IFIT1B	0.039282
ATP6V0D2	0.039268
CES4A	-0.038903
ABCD2	-0.038499
ALAS2	-0.038479
PRRG4	0.038457
CIB3	0.038317
PGM3	-0.038063
C14orf159	0.037530
SLC51B	0.037442
UBE2U	0.037260
PLK3	0.036966
CBR1	0.036900
HSD17B6	0.036883
SESN2	0.036782
LRRC16A	-0.036708
EXOC4	0.036511
ZMAT3	0.036502
FITM1	-0.036355
VTCN1	0.036336
LIPG	-0.036253
TRHDE	-0.035584
CYP2U1	-0.035173
SLC17A4	0.034956
RGS16	-0.034755
OSBPL3	-0.034562
UNC13B	-0.034496
SDR9C7	-0.034384
C9orf142	0.034223
ALDH1B1	0.034077
GNAI1	-0.034037
ERMP1	-0.033976
RNF186	-0.033697
LUM	0.033572
ETNPPL	0.033238
SERPINB1	0.032774
TIFA	0.032581
PFKFB1	-0.032574
PLXNA2	0.032425
ME1	-0.032410
TM6SF2	0.032276
NREP	-0.032218
MTMR11	0.032128
LRTM1	0.032027
SORT1	-0.031965
CTH	0.031673
PRLR	0.031644
FMO2	0.031598
TLCD2	-0.031559
CLPX	0.031509
LZIC	0.031355
PNPLA3	-0.031110
CERS6	0.031028
PHLDA2	0.030878
WEE1	-0.030766
CHI3L1	0.030492
SEL1L3	-0.030346
FASN	-0.030336
RSAD2	0.030274
PPARG	-0.030155
ACACB	-0.030044
THEM5	0.030030
C19orf80	-0.030007
SMPD3	0.029908
PER3	-0.029800
DDIT4L	0.029761
MTNR1A	-0.029500
ACSS3	0.029175
GBP7	0.029169
MOGAT2	0.029040
C8A	-0.029034
SPP1	0.028972
GBP4	0.028831
CD36	0.028797
RARRES1	-0.028716
ERBB4	-0.028590
ASNS	-0.028570
E2F8	-0.028415
ZAK	0.028296
PFKFB3	-0.028222
CYP7B1	-0.028204
CD72	0.027882
IRF7	0.027721
SUCNR1	-0.027706
ARHGAP10	0.027563
DMXL2	0.027560
ABHD2	0.027559
ADGB	0.027487
PDE7A	0.027368
PAQR7	-0.027364
MCM10	-0.027344
SPC25	-0.027230
NNMT	0.027223
LILRB4	0.027156
HOMER2	-0.027016
ACLY	-0.026991
C11orf24	-0.026970
CYP2C8	0.026946
FABP7	0.026892
CIART	-0.026876
MID1IP1	-0.026840
TP53INP2	-0.026839
ITIH5	0.026827
ZFP36L1	0.026809
RHBG	0.026783
NTRK2	0.026759
NUDT7	-0.026659
SORBS3	0.026625
HEXB	0.026525
THEMIS	-0.026390
PLA2G7	0.026382
SDF2L1	-0.026266
AEN	0.026161
PDZK1IP1	-0.026142
AAAS	0.026100
CHRNA4	-0.025952
F11	-0.025949
ISYNA1	0.025928
PPARA	-0.025839
AKR1D1	0.025816
SLC17A8	-0.025783
DHRS9	0.025583
SELENBP1	-0.025554
CLEC6A	0.025542
FOXA3	-0.025507
CYP4A22	-0.025451
FABP4	0.025354
ZNF385A	0.025340
SERPINA11	-0.025240
FAM198A	0.025054
C6	-0.025012
FRZB	0.024951
ODF3B	0.024837
NOTCH1	0.024814
AR	-0.024750
SLC25A30	-0.024611
EFNA3	-0.024607
MPZL1	0.024476
TTC39C	-0.024390
ALPL	0.024389
MID1	0.024345
PDGFC	0.024302
PPP1R3B	-0.024071
CASC4	-0.024041
TMX4	-0.024006
SERPINE2	-0.023962
CENPM	0.023928
OCIAD2	-0.023924
FGL1	0.023897
SERPINB8	-0.023884
C17orf78	0.023824
ABTB2	0.023804
MBD5	0.023777
CRELD2	-0.023637
RTP4	0.023603
CTSC	0.023586
NIPAL1	0.023578
C17orf58	0.023576
CRYL1	0.023526
ALDH3B1	0.023499
NDRG1	0.023483
ELL3	0.023466
TM4SF4	0.023440
ATOH8	0.023323
ACSS2	-0.023252
GEM	0.023221
INHBC	-0.023181
FABP1	-0.023139
SH3BGRL2	-0.023107
ELOVL2	-0.022922
XAF1	0.022901
TLR5	-0.022818
GTDC1	0.022803
RASSF3	-0.022781
PGRMC2	-0.022728
TMEM120B	-0.022716
YPEL2	0.022679
MGMT	0.022601
SEPT11	0.022595
AMN1	0.022566
CD300E	0.022509
RDH11	-0.022489
PAOX	-0.022453
MAD2L2	0.022432
SLC13A3	0.022394
PERP	-0.022376
VCPKMT	0.022373
MFGE8	0.022349
GCH1	0.022332
KITLG	-0.022309
EPHX1	0.022290
PTGDS	0.022242
ETHE1	0.022236
HSPH1	-0.022162
APRT	0.022134
HMGCR	-0.022132
SDC1	0.022116
ARHGEF37	0.022111
AEBP2	0.022055
MGLL	-0.022041
DDX60	0.022021
PDE4B	0.022014
ZYG11A	0.022008
HTATIP2	0.022003
IGFBP2	0.021930
GPR128	-0.021878
TTPA	0.021860
PEX1	0.021816
SLC39A4	0.021693
BAX	0.021671
SLC50A1	0.021666
TMEM62	0.021599
CSNK1G1	0.021589
AASS	0.021535
LHPP	0.021524
LY6E	0.021476
ADAM23	0.021463
MEIOB	0.021441
PLA2G6	-0.021414
HIST1H3G	0.021395
FRAS1	-0.021381
SAMD9L	0.021253
CA1	0.021147
IL22RA1	0.021136
CDHR5	0.021122
PRELID2	0.021068
DUSP14	0.021067
PCSK9	-0.021019
RND1	0.020996
ATP1A2	-0.020993
VAC14	-0.020991
SPATA22	-0.020975
PRAF2	0.020830
STEAP3	0.020806
MGAT5	0.020764
GPD2	-0.020649
PROCA1	-0.020642
TERT	0.020627
HERC6	0.020611
CHRNA2	-0.020573
ZNF705A	0.020565
USP2	-0.020551
DPY19L3	-0.020369
CTGF	0.020351
DTX4	0.020340
TCEAL8	0.020293
TLCD1	-0.020273
GALE	-0.020261
LAD1	0.020241
BLMH	-0.020210
KRT23	0.020196
PNP	0.020177
SULT1B1	0.020056
IFIT3	0.020045
ABCC4	0.019986
ELOVL6	-0.019967
WSB1	0.019955
ABCB10	-0.019937
EEF2K	-0.019876
GSTM1	0.019874
DPP7	-0.019873
RHOBTB1	-0.019866
INSIG1	-0.019834
GADD45A	-0.019798
FCER2	-0.019783
METTL20	0.019779
MFHAS1	-0.019769
FADS3	0.019757
SLC25A22	0.019658
KANSL1L	0.019648
NANOS2	-0.019578
PPARGC1A	0.019572
ODF2L	0.019566
FAM20C	-0.019497
ZBP1	0.019488
KIAA0319	-0.019485
CCL3L3	0.019480
TOB1	0.019405
ZNRF3	0.019384
OLIG1	-0.019343
RAB30	0.019281
STARD4	-0.019254
MTSS1	-0.019243
HSD17B12	-0.019231
RASSF6	-0.019156
SLC23A1	-0.019151
PLIN2	-0.019150
AGTR1	0.019138
PSRC1	0.019072
ALS2CR12	0.019069
CHRNA5	-0.019049
PDE7B	0.019035
UGP2	0.019026
FAM81A	0.019009
GLRX	0.019006
GOT1	0.018995
RHOD	0.018977
ANXA13	0.018962
FAM134B	0.018957
OAT	0.018937
APCS	-0.018872
RTN4	0.018860
ARSA	-0.018776
NEDD4L	0.018766
PRSS1	-0.018755
AIG1	0.018715
NFE2L2	0.018696
LY96	0.018688
DKK4	-0.018687
TRIM24	0.018674
SLC41A3	0.018635
CSRP1	0.018616
SERPINB9	0.018558
RAB8B	0.018501
ZC3H8	-0.018488
LRRC39	-0.018428
ANKS4B	-0.018403
OBP2B	-0.018395
CD59	-0.018348
KLHL6	-0.018314
PFN2	-0.018294
AHR	0.018273
EXTL1	-0.018270
GINM1	-0.018260
CYP3A5	0.018243
TDRP	-0.018212
ARHGEF19	0.018212
NT5E	0.018190
CDCA7	-0.018166
ZDHHC2	-0.018151
HGFAC	-0.018144
NRP2	-0.018131
TTC39B	0.018098
ARHGAP6	-0.018091
PARP12	0.018069
SNRK	-0.018066
VAT1	0.018064
TBC1D7	0.018047
RHBDF2	0.018035
GRK5	0.018010
GLT1D1	0.018004
MVD	-0.018002
S100A14	-0.017989
PPP1R3C	0.017980
CHKA	0.017962
ROBO1	0.017946
TBC1D19	0.017934
FBXO36	0.017892
PQLC3	0.017863
PMM1	-0.017860
MMP7	-0.017860
VLDLR	0.017802
ABLIM1	0.017796
SLC4A4	0.017740
GNRH1	0.017738
OLFML1	-0.017715
CSRP3	-0.017713
EGFR	-0.017696
DSG1	-0.017644
MCC	0.017636
TMPRSS2	0.017620
DDC	0.017606
RIMKLB	-0.017604
CD55	0.017596
MAPKAPK2	0.017588
FAM126B	-0.017586
KIAA1551	0.017583
HYOU1	-0.017578
GMPPB	-0.017569
RSPO3	0.017557
CBR3	0.017550
MUSTN1	0.017545
GAS6	0.017483
SLC22A3	0.017483
SAMD4A	0.017481
ESR1	0.017476
XKR9	-0.017460
ARHGEF9	-0.017424
SUPT3H	-0.017360
TRDMT1	0.017345
ZBTB7C	-0.017322
DDHD1	-0.017278
DNAJC5B	-0.017267
ABLIM3	0.017257
NAP1L1	-0.017219
PPL	0.017210
NT5C3B	0.017210
LRIG3	0.017183
EPPK1	0.017160
A1BG	0.017152
FLVCR2	0.017152
ACACA	-0.017134
PVALB	-0.017112
ZC4H2	0.017107
MEST	0.017104
IL17RB	0.017103
SYTL5	-0.017100
ZNF14	-0.017095
IER5	0.017072
SH3YL1	0.017026
GGH	0.017012
IL1RAP	-0.017008
PCSK5	0.016982
SLC16A10	0.016949
GABRB3	-0.016918
SLC8B1	0.016906
CPM	0.016896
SREBF1	-0.016888
GRM8	-0.016888
METTL15	0.016886
GBP2	0.016873
EFEMP1	0.016808
NSDHL	-0.016799
MYL4	-0.016774
SLC16A13	-0.016730
PMVK	-0.016711
AADACL4	-0.016706
LRRC55	-0.016687
ATP11A	0.016685
GAS7	0.016635
RPIA	-0.016633
IL18BP	0.016608
TFRC	0.016599
DOC2B	-0.016599
NOX4	-0.016582
LTBP4	-0.016564
TLR7	0.016536
CHIC1	0.016517
CLCF1	0.016509
SLC25A15	0.016491