!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!cell_type	Endothelial cells
!drug_id	CID 5757
!drug_name	Estradiol
!organism	Human
!end_metadata
ND2	0.208038
MMP1	0.148099
RPL36	0.103535
HSPB1	0.093628
ITGA5	0.088780
SLC25A6	0.085763
RPS25	-0.085019
FLNA	0.083948
CFL1	0.080429
RPL6	-0.071620
TUBA1A	-0.070447
COL4A2	0.070024
TGFB1I1	0.068688
IGFBP4	0.068232
CNN3	-0.066072
ACTG1	0.065449
RPS26	0.064514
PFN1	0.061629
TKT	0.061596
RASSF3	-0.060392
HAPLN3	-0.059344
RPL39	-0.059275
IFITM3	0.059197
KIAA0485	-0.059160
GABARAP	0.058873
ZNF598	-0.057000
RPL27	-0.056643
RPS10	0.056579
RPL38	-0.056428
MYH16	-0.055038
PHB2	0.054977
HSPG2	0.052959
CYP2C19	0.052698
HLA-C	0.052279
AP2M1	0.052271
TUBB	0.052171
MT2A	0.052123
HLA-B	0.052081
EIF3H	-0.052059
AQP9	-0.051969
CRIP2	0.051884
RPL29	0.051586
TSPO	0.050428
KRT18	0.049932
RPL34	-0.049923
RNASEK	0.049614
RPS4Y1	-0.049569
UQCRC1	0.049157
CCL2	-0.049130
GAPDH	0.049082
ENG	0.048891
IFITM2	0.048824
HNRNPH1	-0.048559
RPL8	0.048273
HLA-A	0.047977
FLNB	0.047869
PPP1R18	0.047782
RPL24	-0.047482
MFAP2	0.047329
COX7A2	-0.047183
CD151	0.047083
TUBB4B	0.047010
PDGFA	-0.046573
ITGAV	-0.046434
PSAP	0.046419
PKD1P1	0.046295
MYH9	0.046137
QARS	0.046100
EIF3E	-0.045848
LAPTM4A	-0.045197
RPS13	-0.045017
C6orf62	-0.044976
RND3	-0.044759
TUBB3	0.044515
TALDO1	0.044435
APP	-0.044397
GJA1	-0.044184
CRIM1	-0.044062
ICAM2	0.043967
GNG11	-0.043919
USMG5	-0.043801
TIMP1	0.043786
RAB13	-0.043763
PRKCSH	0.043750
PPDPF	0.043255
MDK	0.043036
FAU	0.042865
RPL23	-0.042832
FXYD5	0.042549
TMEM258	0.042405
SH3BGRL3	0.042326
RPS14P3	-0.042165
GRN	0.041866
HYI	0.041723
IAH1	-0.041622
PARK7	-0.041557
RPS29	-0.041437
S100A13	0.041305
EFNA1	-0.040795
MZT2A	0.040674
UBC	0.040664
TRAPPC1	0.040560
SRP14	-0.040515
NUMBL	-0.040212
MIF	0.040187
ESM1	-0.040093
CD99	0.039711
RRAS	0.039647
ATP1B1	-0.039409
CRACR2B	-0.039138
SEC22B	-0.039086
PABPC4	0.039086
PLD3	0.038848
P4HB	0.038700
HLA-E	0.038638
TIE1	0.038632
TUBA1C	0.038548
IRF2BPL	-0.038206
MT1H	0.038101
HLA-G	0.037990
FTL	0.037956
S100A6	0.037819
MORF4L1	-0.037214
PRPF8	0.037176
PLOD1	0.036918
CCT3	0.036603
GSTP1	0.036595
FRMD7	-0.036500
CYC1	0.036404
ACTB	0.036353
NPM1	-0.036350
ALDOA	0.036277
RPS4X	-0.036254
CTSA	0.036167
AARS	0.035971
YWHAG	-0.035959
PKM	0.035944
EGFL7	0.035927
ATP5B	0.035869
VIPR2	0.035669
FHL2	0.035529
RPS18	0.035415
MT1HL1	0.035404
CLDN5	0.035211
MAFF	-0.035177
POLR2L	0.035111
AKAP12	-0.035063
GNB2	0.035025
SYNGR2	0.034990
AP2S1	0.034925
MT1X	0.034708
RALA	-0.034706
JTB	0.034658
JAG2	0.034612
VPS28	0.034600
FAM43A	0.034501
BRI3	0.034479
EGR1	-0.034337
MAGED1	0.034241
UXT	0.034158
VPS51	0.034087
S100A11	0.034043
SEP15	-0.033917
ZYX	0.033835
TUBB2B	0.033735
PCBP1	0.033722
RPL22	-0.033646
SDHA	0.033642
FADS3	0.033350
CRELD2	0.033217
RPS21	-0.032947
VAT1	0.032867
B2M	-0.032830
FAM50A	0.032679
PPP1CB	-0.032630
RNF138	0.032622
RPL5	-0.032604
LOC340085	-0.032530
EIF3I	0.032444
ILK	0.032437
VKORC1	0.032095
BANF1	0.032036
COL18A1	0.031923
SPHK1	0.031887
GLTSCR2	0.031860
ND6	-0.031637
GANAB	0.031550
IGFBP7	0.031445
TM4SF1	-0.031421
FCGRT	0.031416
PSMD8	0.031384
CLU	0.031374
ATP5D	0.031362
TUBA1B	0.031354
SRGAP2C	-0.031351
NPIPA1	0.031205
PSMA4	-0.031188
LOC100996255	-0.031171
ABL1	0.031038
PLS3	-0.030782
NACAP1	-0.030706
EBNA1BP2	-0.030693
GSTO1	0.030533
EIF3G	0.030523
SPATA20	0.030467
GNG10	-0.030274
PSMD2	0.030147
TBCA	-0.030141
VMP1	-0.029983
CDY1	-0.029978
CARM1	0.029908
ARPC1B	0.029803
RPL30	0.029726
CHMP2A	0.029725
PTRF	0.029722
ECSCR	0.029656
RIN2	-0.029593
SLC30A2	-0.029393
NME7	-0.029309
FAM129B	0.029305
RHOC	0.029290
HSP90AB1	0.029254
SERPINE1	0.029217
TRAF3IP1	0.029160
RPS17	0.029133
EEF2	0.029078
HGFAC	-0.029048
ESAM	0.029038
OS9	0.028982
RPL14	-0.028949
MARCKSL1	0.028930
PSMB5	0.028918
GPI	0.028892
CLEC14A	0.028840
YBX1	0.028821
SNRPB	0.028749
GOT2	0.028511
CDIPT	0.028499
MYL12A	-0.028493
HGS	0.028315
YWHAE	-0.028121
EMC6	-0.028065
SDF4	0.028007
C8orf4	-0.028001
AKR1B1	0.027948
CSRP1	0.027910
ENO1	0.027885
ADM	-0.027855
NACA	-0.027815
MRPL34	0.027792
UBA1	0.027636
ALDH2	0.027579
SHC1	0.027437
EIF6	0.027352
SSBP4	0.027324
NDUFC2	-0.027293
GLB1	0.027279
RPS3A	-0.027225
VWF	0.026999
RPL3	0.026976
CALM2	-0.026946
MGAT4B	0.026920
RSL24D1	-0.026845
HDGF	0.026824
GOLGA8H	-0.026798
HOMER3	0.026767
SUMO4	-0.026710
EOGT	-0.026650
DUS1L	0.026640
DAP3	-0.026545
PIP5K1C	0.026419
CDC42EP5	0.026385
TTYH3	0.026315
PPIA	0.026210
C12orf57	0.026184
PPP1CC	-0.026181
C19orf53	0.026170
SHANK3	0.026105
LOC100289333	-0.026091
LINC00094	-0.025979
PCDHGA8	-0.025949
NELFE	0.025930
RPL9	-0.025898
UQCRB	-0.025881
MYL6	-0.025876
RPL22L1	-0.025828
CLSTN1	0.025808
MYL9	0.025752
DYNLL1	0.025740
ADRM1	0.025664
RHOA	0.025617
ACADVL	0.025580
ID3	0.025422
TFPI2	0.025405
NME4	0.025385
IL32	0.025214
VIM	0.025191
NDUFA4	-0.025165
ARGLU1	-0.025145
NPDC1	0.025125
HIGD2A	0.025065
ATG3	-0.024885
PKN1	0.024841
SERPINH1	0.024810
DOK2	0.024798
PUF60	0.024727
MVP	0.024721
PEA15	0.024706
ARL6IP4	0.024683
UNC50	-0.024646
RNF11	-0.024613
CAPNS1	0.024572
CDH13	-0.024571
LINC00880	-0.024479
GRHPR	0.024449
RABAC1	0.024396
SMURF2	-0.024389
SLC29A1	0.024200
MRPL37	0.024172
ATPIF1	-0.024115
ERP29	0.024088
COCH	-0.024064
ABHD17A	0.024053
PDIA6	0.024018
HTRA1	0.024010
MCAM	0.024005
WSB2	-0.023981
ACTN4	0.023973
ZNF490	-0.023935
HIST1H4C	-0.023933
LTBP2	0.023917
CS	0.023916
TMA7	-0.023822
RGL2	0.023665
PFKP	0.023613
ATP6AP1	0.023593
PRDX5	0.023572
PPP2R1A	0.023535
FIS1	0.023506
RAB1A	-0.023493
MRPS24	0.023470
MSH3	-0.023451
MGLL	0.023404
SGK223	0.023363
EIF4H	0.023326
TMSB15A	-0.023324
ADSL	0.023254
CHP1	-0.023242
NUCKS1	-0.023230
C17orf49	0.023223
UBE2S	0.023218
LOC100288911	0.023217
CCT7	0.023188
PPP1R13L	0.023148
NDUFV1	0.023116
CTGF	0.023086
HMGN1	-0.023085
C19orf43	0.023044
HOXB2	-0.023013
TCF7	-0.022994
DDB1	0.022959
PXN	0.022951
SLIRP	0.022925
LMNA	0.022913
NARF	0.022899
NDUFAF3	0.022817
TNPO1	-0.022796
PLOD3	0.022771
FAM213A	0.022725
DEXI	0.022639
CD34	0.022638
HK1	0.022638
ANXA1	-0.022636
RPL36AL	-0.022615
TMEM214	0.022555
TOMM20	-0.022551
RPL36A	0.022533
LRRC10B	0.022516
NPLOC4	0.022500
LXN	0.022475
FLOT1	0.022466
GAS5	-0.022419
BGN	0.022418
DYSF	0.022377
SLC7A5	0.022323
PPP3CA	-0.022317
GADD45A	-0.022278
DRAP1	0.022277
NPTN	-0.022244
HPCAL1	0.022237
ROMO1	0.022230
PIM3	0.022202
LAMTOR1	0.022191
STMN1	-0.022187
C17orf58	-0.022152
DDX21	-0.022147
CTDNEP1	0.022120
ANXA2P2	-0.022045
H1FOO	-0.022026
MANF	0.021928
PTDSS1	0.021918
PTCHD1	-0.021877
MMP2	0.021847
MT1F	0.021838
RPSA	-0.021731
HMGA1	0.021661
APLN	0.021646
SRGN	-0.021634
SSBP3-AS1	-0.021591
SEC11A	-0.021577
PCMTD1	-0.021525
RAB5C	0.021525
TFPI	-0.021480
ETHE1	0.021479
SKP1	-0.021454
EEF1B2	-0.021340
EIF4EBP1	0.021340
ANGPTL4	0.021327
VAMP8	0.021296
COX3	0.021232
KLF10	-0.021212
XPOT	-0.021194
AHCY	0.021190
SLC25A39	0.021160
RNF4	0.021140
MYL6B	0.021101
RNH1	-0.021088
TAGLN	0.021078
ATP6V1F	0.021058
YIF1A	0.021048
NOP58	-0.021014
TBCB	0.020968
EMP3	0.020904
SF3B5	-0.020887
COL4A1	0.020878
WTAP	-0.020826
FLII	0.020810
HLA-F	0.020808
TRMT112	0.020784
EIF2S2	-0.020774
MEA1	0.020759
TLE2	0.020742
RPS7	-0.020739
PLIN3	-0.020723
PMPCA	0.020694
NARS	-0.020687
CLDN19	-0.020639
CDK4	0.020605
NDRG4	0.020603
CST3	0.020599
SH3GL1	0.020585
NOB1	0.020566
SRM	0.020557
SH2B3	0.020545
MAP1B	-0.020523
TGFB1	0.020523
DSTNP2	-0.020518
EML3	0.020514
UBL5	0.020486
SNRPD2	0.020466
ZNF320	-0.020465
MYCT1	-0.020432
ANXA7	-0.020428
YWHAQ	-0.020402
ACTN1	0.020343
PLP2	0.020343
SUMO2	-0.020316
IRAK1	0.020304
RPS15A	-0.020253
BCAP31	0.020229
MED15	0.020214
RAPGEFL1	0.020156
BAG6	0.020143
URM1	0.020116
C6orf48	-0.020077
UFSP1	-0.020074
RHOG	0.020050
BLOC1S2	-0.020036
IMPDH2	0.019997
MPST	0.019953
APLP2	0.019939
DUSP26	-0.019890
COX8A	0.019857
PRELID1	0.019853
SHMT2	0.019849
FURIN	0.019840
MYO1E	0.019834
PDIA5	0.019817
CDC37	0.019793
PSME1	0.019777
RPL27A	-0.019768
FTH1	-0.019763
STK24	0.019750
TUFM	0.019741
MRPL17	-0.019737
ARHGDIA	0.019710
JUP	0.019703
PSMD3	0.019701
NAP1L1	-0.019679
ANXA2	-0.019656