!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Pioglitazone
!smiles	CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
!drugbank_id	DB01132
!pubchem_cid	4829
!cell_type	NA
!organism	human
!end_metadata
MYH1	-0.124824
RPS18	0.114617
TNNT1	0.104352
RPL41	0.099113
RHOQ	0.094815
FHL1	-0.093326
XIRP2	0.092680
COX7A1	0.092256
CSRP3	0.091657
ENO3	-0.091181
TNNI1	-0.090710
S100A1	0.089912
MYLPF	0.089768
COX6A2	0.085339
OAZ1	-0.084372
TMOD4	0.081348
MRPS10	0.080944
CKM	0.080246
CHCHD10	0.078983
RILPL1	0.078494
ATP6	-0.078287
HBB	0.077987
GAPDHP62	-0.077591
RPL23A	0.076732
CRYAB	0.074069
MYBPC1	-0.072075
RPL3	0.071330
MYL2	0.069899
RPL26	0.068346
HSPB6	0.067956
RPL21	0.067728
HSPA8	-0.066215
RBM38	-0.065023
MRPL48	0.064249
NDUFA12	0.063720
MYH2	-0.059750
RPL30	0.059276
SMTNL1	-0.058899
PYGM	0.058605
FABP4	0.058582
RPL32	0.058178
PTPRO	0.058053
HCN3	0.057976
SNHG5	-0.057975
RPS26	0.057975
COX3	-0.057750
RAD51D	0.056812
CKMT2	-0.055063
SPRR4	0.054230
MYH4	-0.053795
ALDH2	0.053320
SLC25A3	-0.052634
E2F4	0.052392
MT2A	0.052212
RPL36A	0.051814
CASQ2	0.050896
NRD1	0.050653
COX2	0.050473
MYH7	0.050453
TMEM117	0.050126
DHX32	0.050063
COX1	-0.049662
EFR3A	0.049577
ACTA1	-0.048745
PKIA	0.048106
RPS27	0.047907
POPDC3	0.047846
VGLL2	0.047822
RAD23A	0.047493
CERS2	0.047185
ND2	-0.046945
COL3A1	0.046941
COL1A1	0.046704
IFITM3	0.046667
ATP1A2	0.046226
RPL29	0.046196
TNNC2	-0.046180
RPLP0	0.046020
C10orf71	0.045834
RPS15	0.045528
TRIM63	-0.045441
FTL	0.045254
C20orf166	0.045227
EEF1A2	0.045100
CS	0.044987
RPS3A	0.044324
LOC101927131	0.044154
RPS4X	0.043978
ANKRD2	-0.043968
LINC01405	0.043946
ASB5	-0.043669
HSD17B4	0.043536
RPS17	0.043420
GNAS	0.043303
LDHB	0.043124
RPL22	0.042845
NDRG2	-0.042793
EIF1	0.042100
RPS3	-0.042086
MTCH1	0.041509
COL1A2	0.040702
ATF4	-0.040398
CSDE1	-0.039894
CHCHD2	0.039885
MYOZ1	0.039642
MURC	-0.039367
MAMSTR	0.039256
SLC2A1-AS1	-0.039189
IFITM2	0.038985
CAP2	0.038961
CASQ1	-0.038613
PDZD9	0.038553
ADIPOQ	-0.038172
ZRANB2	0.037980
RPL37A	0.037908
CES4A	0.037858
THBS4	0.037826
UBA52	0.037626
PGAM2	-0.037525
YWHAG	0.037072
GOT2	0.036930
LMOD2	0.036773
KLHL41	-0.036680
TRAPPC4	0.036558
MRPS24	0.036441
LURAP1L	0.036377
RPS24	0.036012
SGK1	0.035981
FXYD1	0.035772
ACTN2	-0.035571
MRPL34	0.035369
FKBP5	-0.035154
BCL6	0.034970
NSA2	0.034897
ABCA11P	0.034878
RPS21	0.034738
TUBA1A	0.034658
NMRK2	-0.034560
HHATL	-0.034513
NPHS2	0.034461
ND6	-0.034353
CISD1	0.034293
NDUFA3	0.034060
TMEM70	-0.034028
LGI2	0.033743
CECR5	0.033693
LOC101928896	0.033661
SH3BGR	0.033621
EEF1B2	-0.033551
RPL31	0.033380
BMS1P6	-0.033183
KIAA0894	-0.033123
ACSL1	0.032976
VPS25	0.032954
SLC25A36	0.032847
FN1	0.032679
ATP5C1	0.032626
LOC100506858	0.032279
DES	-0.031794
NDUFA8	0.031664
RPL39	0.031395
ITIH2	0.031262
FTH1P5	0.031026
EEF2	0.030960
RPS16	0.030744
AP1G2	-0.030671
AGL	-0.030531
MAP2K1	0.030406
COA6	0.030314
SNHG6	-0.030260
APOBEC2	0.030146
SERBP1	0.030055
FABP3	0.029784
RPL6	-0.029773
CD63	-0.029745
NDUFB5	0.029578
LOC221814	0.029568
COL6A3	0.029327
RPL35	0.029315
VDAC2	0.029128
LOC729658	0.029095
BTBD6	-0.028948
MT1E	0.028865
MANF	0.028862
AK3	-0.028760
ANKRD1	0.028554
ZNF385A	0.028487
RPS25	-0.028205
HADHB	0.028127
MT1HL1	0.028110
RPL12	0.028046
PPP1R1A	0.028002
GABARAP	0.027979
UQCRFS1	-0.027945
PLA2G2D	0.027857
RPL24	0.027798
SLAMF6	0.027743
ALDOA	-0.027675
SMCO1	0.027613
YARS	0.027592
BMF	0.027446
NRAP	-0.027406
IL32	0.027364
MYO18B	-0.027272
CEBPB	-0.027247
MRPL3	0.027188
SLC22A16	0.027152
ANP32C	-0.027126
WWP1	-0.026960
CLUH	-0.026900
NFE2L1	-0.026814
SMAD5	0.026742
MALAT1	-0.026712
SMTNL2	-0.026598
STARD7	0.026573
CLDN19	-0.026567
CERS3	0.026546
GAPDH	-0.026315
NRM	0.026249
HMGN2	0.026234
C8orf22	0.026210
PIPOX	0.026157
YWHAE	0.026027
RPL27	0.025988
ZNF582	0.025901
USMG5	-0.025899
PSG5	0.025647
MYPN	0.025616
KAT7	0.025576
CKB	-0.025492
TMSB4Y	-0.025424
ZFP91	0.025396
TUBA4A	-0.025343
GMPR	-0.025249
PGK1	-0.025137
TMSB10	0.025098
PCBP1	0.025051
HSPB7	-0.025029
UCP2	0.025018
RPS6KA1	0.024982
LUM	0.024968
TPI1	-0.024892
RPL15	0.024865
EEF1A1	0.024739
STAC3	-0.024734
PSME1	0.024669
TMEM121	-0.024664
FIS1	-0.024621
TXNIP	0.024461
SDHD	0.024423
PPDPF	0.024363
SLIRP	0.024299
NDUFB1	-0.024073
PLCD4	0.024061
LOC101928476	0.024026
IPO4	-0.024019
GYS1	0.023964
IER5	-0.023926
PCAT19	-0.023893
FUT5	-0.023865
SRL	0.023846
SULT1B1	0.023844
HRES1	-0.023817
ARHGEF40	0.023807
AQP1	-0.023688
SEPW1	-0.023638
GBE1	0.023599
INTS8	-0.023510
LOC440602	0.023477
XIRP1	0.023457
C2orf74	0.023326
TRIM36	0.023267
VGF	-0.023231
FEZ2	-0.023210
SRP14	0.023141
MYL6	-0.023127
ATPIF1	-0.023110
RPL14	0.023011
LINC01222	0.022994
NGRN	-0.022905
RPL13A	0.022849
KAAG1	-0.022701
MYOZ2	-0.022678
AMPH	0.022623
PPIA	0.022591
GNB2	-0.022535
C1orf200	0.022488
SDHA	0.022447
LINC01512	0.022413
AMN1	0.022409
FITM1	0.022195
HLA-A	0.022159
KLHL31	0.022125
LINC00491	0.022012
CDIPT	0.021989
ADAM15	-0.021981
SLC5A5	-0.021923
PLCB3	-0.021911
CACNG4	0.021909
GNG11	0.021778
FAM217B	0.021738
UQCRH	-0.021660
ZNF106	-0.021641
MSRB1	0.021553
NXN	0.021542
KIAA1279	0.021527
BTF3	0.021523
GPD1L	0.021460
FBN3	0.021379
ABRA	0.021378
MRFAP1	0.021373
CFL1	0.021365
BTF3L4	0.021329
NEK7	0.021324
ATP5A1	-0.021289
PGA3	0.021273
RPS11	0.021261
CACNA1S	0.021243
SNRPC	0.021234
PPP3CA	0.021224
CMYA5	0.021218
SIDT2	-0.021184
CAPN3	-0.021139
POLA1	0.021076
PLXNB3	0.021062
PABPC3	0.020972
PIK3R6	0.020945
BAG6	0.020906
VDAC1	-0.020900
NDUFB3	-0.020893
PLEKHA5	0.020870
JPH1	0.020813
BIRC7	-0.020774
RPS14P3	0.020716
RPL4	0.020702
UNC45B	0.020665
ZCRB1	0.020659
CD36	0.020584
EIF2D	0.020570
PSAP	-0.020526
UBB	0.020459
CHTF8	-0.020452
STK25	-0.020405
GOLGA6L10	-0.020391
ATP5B	-0.020347
SLC6A18	-0.020344
CEP170B	-0.020326
AKR1C3	0.020310
SSC5D	-0.020280
JSRP1	-0.020272
MLIP	0.020259
SUMO2	0.020180
LZTS3	0.020174
TMEM52	0.020119
HINT1	0.020091
FLJ20021	-0.020072
B2M	0.020068
TMEM2	0.019992
LGALS3	0.019981
RASA4	-0.019973
MT1H	0.019926
FAM132A	-0.019862
ZNF524	-0.019853
SELK	-0.019839
N4BP1	0.019824
LSMEM1	0.019818
NT5C	-0.019816
GAMT	-0.019794
LOC100129935	0.019735
ARL6IP5	0.019705
CARNS1	0.019680
XKR8	-0.019668
KPNA3	0.019635
KRT82	0.019612
CWC15	0.019597
SLC25A4	-0.019573
UBAP2	0.019552
RPS23	0.019534
UBE2NL	0.019509
CYC1	0.019482
BANF1	0.019457
COX16	0.019444
FABP5	0.019434
MTCH2	0.019429
PSMC3	-0.019401
UBE2G1	0.019398
FAM213B	0.019355
LOC100507630	-0.019315
CDCA4	-0.019305
HAMP	-0.019270
RAB3IL1	0.019253
MNDA	0.019249
OR1D2	0.019184
PPA1	0.019169
LOC100129361	0.019130
IRF2BPL	0.019116
LINC00116	-0.019089
PPP2R3A	0.019057
PKD1P1	0.019010
RAB12	0.018935
FAM206A	0.018931
CLEC1A	0.018927
RPS7	-0.018903
IL17D	0.018898
NTF3	0.018887
SLC24A3	-0.018857
NFATC2IP	0.018829
MT1F	0.018772
IDH1	0.018742
KRTAP5-8	-0.018673
ARMC5	-0.018625
STRADB	0.018624
RPN1	0.018594
GDF2	-0.018580
NPIPA1	0.018575
LINC00844	0.018558
CHMP1A	-0.018501
RNF20	0.018455
APBA2	-0.018434
PALM	-0.018432
H1F0	-0.018416
COX7A2L	0.018411
SUCLG2	0.018371
MLF1	-0.018281
NPIPB15	-0.018273
MT1X	0.018221
LCN12	-0.018173
MYH9	0.018173
TSPAN12	0.018098
ATRX	0.018047
UTS2R	-0.017990
MYL12B	0.017973
CFL2	0.017966
CYP46A1	-0.017963
NEXN	0.017947
MXRA5	0.017909
TDRG1	0.017827
GPR144	-0.017820
TUBA4B	-0.017746
RPS29	-0.017745
SPARC	0.017729
ATP5H	0.017727
PLEKHJ1	-0.017673
TRMT112	0.017627
ACYP2	-0.017604
XIST	0.017601
FAM104A	0.017592
COX5A	0.017579
B4GALT5	0.017562
NUDT4	0.017553
LOC285556	-0.017549
CA3	-0.017491
TRAPPC8	-0.017468
STRN3	-0.017440
MYF6	0.017379
RPL13	0.017370
ASB16	-0.017361
TBL3	-0.017357
NAV2-AS4	0.017343
ADCK3	-0.017331
FMO2	0.017328
PNPLA2	0.017313
TSPAN7	0.017278
INSM2	0.017229
CYSTM1	-0.017177
C12orf75	0.017168
LAPTM4B	0.017143
PAK3	0.017139
FLJ36848	0.017113
MAN2A1	0.017097
SNHG7	0.017077
NEDD1	0.017068
TXLNB	-0.017026
TOB1	0.017001
TRIM22	0.016999
TPSG1	-0.016991
IARS2	0.016980
KIAA0247	-0.016963
FURIN	0.016946
ATP11B	-0.016943
NEURL1B	0.016939
WNT10B	0.016921
LINC00998	0.016914
LGALS1	0.016877
SH3BP1	0.016869
LPL	0.016866
TSG101	0.016839
LOC100287497	0.016793
NCOA4	0.016791
SYNPO2L	0.016743
TFRC	-0.016722
PSG2	0.016719
FAM127A	0.016700
OAZ2	-0.016687
NECAP1	0.016661
TIPARP-AS1	0.016660
SPRYD3	-0.016612
ASB15	0.016598
NCKAP1L	-0.016586
ENGASE	-0.016570