!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	PLX4032
!drugbank_id	DB05238
!cell_type	M229_R5 melanoma resistant sub-line
!organism	human
!end_metadata
DUSP6	-0.135221
SPRY4	-0.092357
EGR1	-0.089676
HBEGF	-0.082116
SPRY2	-0.071965
IL11	-0.067908
LIF	-0.065063
IL1B	-0.064843
CTGF	-0.064827
EPHA2	-0.064283
CXCL8	-0.061364
DUSP5	-0.059861
MEDAG	-0.058785
AREG	-0.056884
SEMA7A	-0.056412
IFIT1	0.056133
EMP1	-0.055795
SH2B3	-0.055271
INHBA	-0.053747
MIR221	-0.052354
ERRFI1	-0.051241
NAV3	-0.048703
NFKBIZ	-0.048206
DUSP4	-0.047725
RGS4	-0.046950
TMCC3	-0.045441
ITGB8	-0.045327
ETV5	-0.045128
PHLDA1	-0.044577
ARHGAP28	0.044093
C3orf52	-0.043500
AKR1B10	0.043479
SHC4	-0.042970
MICALCL	-0.042707
F2RL1	-0.042337
SLC16A6	-0.041672
PLAU	-0.041622
GFPT2	-0.041427
SPRED2	-0.040231
SLC20A1	-0.040207
CDKN1A	-0.039942
PLAUR	-0.039907
SH3RF1	-0.039689
IER3	-0.039633
STC1	-0.039501
MCL1	-0.039469
MYEOV	-0.039157
GEM	-0.038816
MMP3	-0.038765
TNFSF15	-0.038643
IL1RAPL1	-0.038611
TMEM100	0.037056
ANKRD1	-0.036947
SPSB1	-0.036804
SPRED1	-0.036741
SERPINB8	-0.036218
STX1A	-0.035662
CCND1	-0.035623
IL12A	-0.035410
PDCD1LG2	-0.035393
BCL2A1	-0.035267
TNFRSF9	0.035130
ETV1	-0.034905
RAB30	0.034743
NEDD4L	-0.034714
IER2	-0.034706
DUSP7	-0.034648
FBXO16	0.034643
MAP2K3	-0.034394
ID3	0.034356
SMURF2	-0.034053
MSC	0.033897
F3	-0.033825
LONRF2	-0.033686
DCSTAMP	-0.033669
PHC2	-0.033630
PNP	-0.033596
CASP4	-0.033537
CHIC2	-0.033463
DUSP1	-0.032921
LDLR	-0.032901
RASA2	-0.032747
NPY4R	0.032711
FAM49A	0.032629
ITPRIP	-0.032411
BHLHE40	-0.032080
BMF	0.032044
EGR2	-0.031907
ELK3	-0.031840
TOP1	-0.031828
USP53	-0.031630
GATSL3	-0.031248
PCDH18	0.031170
ZSWIM6	-0.031145
ADAMTS1	-0.031133
HIST1H1T	0.031041
LINC00189	-0.030948
SERPINB2	-0.030908
ARID3B	-0.030850
PARP9	0.030756
CLDN1	-0.030746
BCL2L11	0.030611
TNFRSF10D	-0.030497
RAPH1	-0.030408
ITGA2	-0.030228
ALX1	0.029919
B3GNT2	-0.029912
SAMD4A	-0.029823
MFSD2A	-0.029554
DACT1	0.029544
PPP1R3C	0.029447
MAFF	-0.029316
HMGA2	-0.029255
SRGAP1	-0.029191
BCAR3	-0.029044
EIF5A2	-0.028847
LDB1	0.028814
INHBE	0.028645
NET1	-0.028620
FOXD1	-0.028603
CHST11	-0.028573
SMAGP	-0.028373
RGS17	-0.028255
SLC2A3	-0.028084
KRT34	-0.027906
GCH1	-0.027815
IFIT2	0.027805
TMEM87B	-0.027767
SLITRK6	-0.027765
NR4A2	-0.027647
RASA3	-0.027633
AMOTL1	-0.027587
PLD1	0.027580
ZNRD1-AS1	0.027509
CD274	-0.027451
PAX6	0.027232
ZSCAN31	0.027204
PPARGC1A	0.027178
MIR29A	-0.027170
TRIM55	-0.027082
FOLH1	-0.026991
WDFY2	-0.026954
CEP170	-0.026944
ZNF845	0.026886
CD24	0.026788
UCN2	-0.026786
MAP1A	0.026780
HIST2H2BE	0.026572
ZNF705A	0.026509
DLEU1	0.026502
MMP1	-0.026454
BLID	-0.026395
SLC38A3	0.026395
KPNA4	-0.026374
PDP1	-0.026373
B3GNT5	-0.026365
GREM1	0.026311
LIMK2	0.026292
VEGFA	-0.026200
FAM83G	-0.026113
TXNIP	0.026100
LIPH	-0.026067
NEK10	-0.025947
SLC25A37	-0.025946
ADAMTS6	-0.025940
IL4R	-0.025920
SAT1	-0.025705
PTHLH	-0.025519
TET1	0.025487
TBC1D10A	-0.025484
ACTR3C	0.025410
HAS2	-0.025378
BICD1	-0.025372
SPHK1	-0.025341
METTL7A	0.025301
C2CD2	-0.025150
AGPAT9	-0.025139
TMEM56	0.025022
ARSJ	-0.024988
NABP1	-0.024936
TM4SF1	-0.024790
RBM43	0.024705
EEPD1	0.024700
TRIM8	-0.024674
DDB2	0.024673
ETS1	-0.024653
FAM198B	0.024621
FAT4	0.024617
SDC4	-0.024564
CPEB4	-0.024494
RAP1GAP2	-0.024474
PTPRE	-0.024461
FRK	0.024438
FAM111B	0.024395
TMEM229B	-0.024388
IRAK2	-0.024348
HK2	-0.024334
CA8	0.024302
AMIGO2	-0.024269
LOC100131860	0.024212
GBP2	0.024208
E2F7	-0.024175
ENTPD7	-0.024113
CDC42EP2	-0.024103
SSBP2	0.024103
LOC344887	0.024018
WWTR1	-0.023928
EGR3	-0.023908
UGCG	-0.023903
WNK4	-0.023876
TAF4B	-0.023696
AGO2	-0.023695
TSPAN2	0.023578
MYADM	-0.023577
LOC81691	0.023511
FAM60A	-0.023471
SOWAHC	-0.023378
LMOD1	0.023314
CHAC1	0.023296
ARHGAP24	-0.023289
MPV17L	-0.023251
TSC22D3	0.023135
TMEM2	-0.023123
MEIS1	0.023120
EHHADH	0.023030
KRTAP10-11	-0.023014
FOSL1	-0.022953
C5orf34	0.022874
LIAS	0.022859
LRRC8C	-0.022835
ABL2	-0.022803
SLC4A7	-0.022788
PMEPA1	-0.022749
PIK3R1	0.022742
PAPL	-0.022638
RAC2	-0.022622
LIFR	-0.022606
TUBA3FP	0.022582
KIAA1377	0.022518
HOMER1	-0.022509
KBTBD7	0.022479
LINC00917	-0.022467
TTC30B	0.022460
CAPRIN2	-0.022430
HIVEP3	-0.022315
EYA1	0.022310
STARD13	-0.022292
TMEM156	-0.022249
XKRX	-0.022203
TLDC1	-0.022187
IDH1	0.022180
MRAS	0.022142
SUOX	0.022124
HIST1H2BG	0.022086
ZNF608	0.022017
FAM160A1	0.021995
MYC	-0.021978
UPP1	-0.021966
MAFB	0.021886
SESN3	0.021861
STK17A	-0.021816
EPHB3	0.021804
EPN2	-0.021691
CAMKK1	0.021674
GSTA4	0.021661
GLI1	0.021657
ARRDC4	0.021630
EFTUD1	-0.021618
FAM227A	0.021579
RICTOR	-0.021564
BNC1	-0.021522
RASSF8	-0.021498
SMAD1	0.021490
KIAA0513	0.021476
IL6	-0.021471
ARMCX4	0.021461
UNC5C	0.021443
CNKSR3	0.021428
ZNF397	0.021395
RUSC2	-0.021382
DKK1	-0.021331
P2RX7	0.021316
CDK17	-0.021293
NREP	0.021277
LRCH1	-0.021268
TET3	-0.021268
REP15	-0.021248
HIST1H1A	0.021230
RGMB	-0.021209
GAS6-AS1	0.021188
RAET1E	-0.021177
PIK3R3	0.021154
TSPAN14	-0.021114
HIST4H4	0.021109
PTCD2	0.021076
FAM229B	0.021016
ZNF546	0.020990
PRKCD	-0.020962
ZNF33B	0.020943
UBALD2	-0.020936
HIVEP2	-0.020918
TPBG	-0.020905
VIT	0.020889
TMEM144	0.020856
LHFPL2	-0.020845
WDR91	0.020835
RAB29	0.020818
DCLRE1A	0.020806
DPP4	0.020804
FMNL2	-0.020798
KLF6	-0.020797
PTPN12	-0.020792
PCYT1B	0.020791
EVA1A	-0.020746
ASF1A	0.020662
SLC2A12	0.020653
ZNF431	0.020578
HTR7	-0.020572
LPXN	-0.020553
C15orf54	-0.020549
STAMBPL1	-0.020545
DAW1	-0.020534
PDGFA	-0.020526
ZMYM3	0.020476
KANK4	0.020446
ANGPTL4	-0.020443
ZFP69B	-0.020430
NAB2	-0.020430
RTP3	0.020395
IRF4	-0.020395
BBS5	0.020370
LOC339803	0.020356
MTUS1	0.020310
KLHL3	0.020290
PDGFRB	0.020254
ZNF10	0.020244
ID2	0.020230
SUGT1P1	0.020221
ERMARD	0.020173
PIK3C2B	0.020155
CORO2B	-0.020117
NHLRC1	0.020111
TNFRSF19	0.020110
LOC100130876	0.020095
CCDC77	0.020085
FLJ16171	-0.020052
BACH1	-0.019963
SLC35F2	-0.019910
EPB41	0.019875
HSPA1L	0.019854
GPR132	-0.019850
NR0B1	0.019832
LOC101928673	0.019832
DUSP19	0.019805
GRB14	-0.019804
HIST3H2A	0.019757
AKAP12	-0.019747
TBC1D8	-0.019712
SLC2A14	-0.019690
STK17B	-0.019652
ETV4	-0.019645
TNFRSF10B	-0.019638
PITPNC1	-0.019575
CARD10	-0.019571
CEP162	0.019549
STK40	-0.019543
SMAD6	0.019515
C4orf29	0.019514
ARHGAP22	-0.019510
MKS1	0.019486
C4orf33	0.019477
CDC14A	-0.019448
HIST1H3J	0.019408
ATP2B1	-0.019401
ANKRD7	0.019392
ADAM21	-0.019362
KLF12	-0.019348
OSGEPL1	0.019334
NADK2	0.019332
FLI1	-0.019304
DOT1L	-0.019255
GPR1	0.019252
CYR61	-0.019249
USP12	-0.019176
ADHFE1	0.019162
MAP3K5	-0.019148
IRAK1BP1	0.019135
KDM7A	-0.019121
HIVEP1	-0.019094
WDR17	0.019078
ZNF619	0.019031
MAMLD1	-0.019010
LOC100133106	-0.018971
C6orf141	-0.018954
ZNF221	0.018938
MUC13	-0.018936
SMOX	-0.018874
TRAF3IP2	0.018865
HSD17B7P2	0.018846
PAG1	-0.018832
MDM1	0.018791
SHB	-0.018785
CSRNP1	-0.018777
PPP1R15A	-0.018743
IFIT5	0.018742
STAT2	0.018739
HSPA4L	0.018735
JUN	-0.018688
PTCH1	0.018664
B3GNT7	0.018662
RIPK2	-0.018649
MIR181B2	0.018631
ARNT2	-0.018627
KCNN4	-0.018614
GPCPD1	0.018602
E2F8	0.018579
CREB3L1	0.018492
PUS10	0.018489
PLCD4	0.018473
CCDC171	0.018427
SNORA36C	-0.018427
RNASEL	0.018421
RPGR	-0.018410
TOB1	0.018394
LINC00312	0.018361
TIAM2	0.018327
UBASH3B	-0.018326
UAP1	-0.018311
KSR1	0.018303
PHLDA2	-0.018259
SLC25A27	0.018254
AMPD3	-0.018234
FHL2	-0.018230
PRSS22	-0.018210
DET1	0.018184
IRF2BPL	-0.018175
BRCA1	0.018151
STK10	-0.018128
SESTD1	-0.018108
KLF5	-0.018089
CRISPLD2	0.018016
POLA2	0.017989
ITGB6	-0.017982
BAMBI	0.017978
BCL2L1	-0.017954
TUBB2B	0.017954
EHD1	-0.017952
ZHX2	0.017949
NRIP1	-0.017926
MB21D2	-0.017921
MYLIP	0.017920
C6orf99	-0.017909
ANGPT1	0.017898
ZNF138	0.017886
HIST1H3H	0.017874
LOC399886	-0.017867
DDX21	-0.017857
FLJ43315	0.017853
ABCB6	0.017823
SIMC1	-0.017812
GPRC5B	0.017798
FIGN	0.017753
ARMCX2	0.017750
TP53	0.017721
PAGR1	0.017720
BBS4	0.017706
MLPH	-0.017693
ARHGAP20	0.017666
NOX4	0.017647
AEN	-0.017638
ARMCX1	0.017612
GNAO1	0.017597
HPCAL1	-0.017597
C1QTNF9	0.017590
ZBTB20	0.017588
SH3TC2	-0.017586
KIT	0.017573
FAM180A	-0.017571
CELF2	-0.017535
MEIS2	0.017523
TPD52L1	0.017517
IRS2	-0.017514
CCNG1	0.017505
ZBTB21	-0.017490
SMURF1	-0.017428
SPANXD	-0.017426
GDPGP1	0.017399
PEX12	0.017399
KIF21B	-0.017392
SERPINB9	-0.017386
RNF141	0.017363
OSMR	-0.017363
CDC25B	0.017354
HMMR	0.017352
DBP	0.017346
FAM161A	0.017338
RBBP9	0.017331
GSTM2	0.017326
SLC38A4	0.017298
ETV6	-0.017293