!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	mammary cells
!organism	mouse
!end_metadata
PER1	0.150497
TMEM86A	0.118841
TTPA	0.105489
ARRDC2	0.105069
CDKN1A	0.076360
PLIN4	0.076105
SERPINE1	0.074965
PDK4	0.074592
FOXRED2	0.073355
SH3BP2	0.063568
F3	0.062953
BNC1	0.062844
SPHK1	0.061943
ZFP36	0.058192
MIDN	0.057633
NFKBIA	0.056524
MCF2L	0.056383
ID3	-0.054145
GPR146	0.053553
OTUD1	-0.053207
PTGS2	-0.050136
ERRFI1	0.049762
KLF10	-0.049199
KIAA1551	0.048453
GADD45G	0.046574
CELSR1	0.046312
OGN	0.045103
TSC22D3	0.045062
EPPK1	0.045035
MICALL1	0.044624
CSRNP1	0.043388
CITED2	-0.042573
CTGF	0.042419
SUOX	0.041591
CEBPB	0.041408
KLF9	0.040789
SGK1	0.040449
IL6R	0.038806
PER2	0.038804
HGFAC	0.038400
TIPARP	0.038207
PHLDA1	-0.038122
DNAJB4	0.037834
TFAP4	-0.037652
SNRK	0.037497
FOS	0.037468
WFS1	0.037339
TGFB2	0.036242
BHLHE40	0.035701
ELMO3	-0.035648
SNED1	0.035246
TNXB	0.034689
ZFP36L1	-0.034438
ANKRD1	-0.034085
AREG	-0.033786
EHHADH	0.033601
CDC42EP2	-0.033392
JADE2	0.032959
SPSB1	0.032883
TSC22D2	-0.032699
VPS37B	0.032285
C16orf54	-0.032248
SMAD6	-0.032227
PLEKHG3	0.032099
ADAMTS1	-0.031843
ACOT11	0.031836
ANKRD52	0.031545
FSTL3	0.031452
SOX9	0.031345
HSD17B8	0.031274
TEAD4	0.031273
PIM1	0.031071
NSRP1	0.030875
ST6GALNAC4	0.030832
CACNA1C	0.030780
SPACA1	-0.030581
JUN	-0.030472
AJUBA	-0.030330
DUSP14	-0.029840
RHOU	0.029807
SOCS5	-0.029632
VEGFA	0.029603
LDLRAP1	0.029581
SCUBE2	0.029570
AKAP2	0.029563
C4orf22	0.029516
IER3	-0.029080
PHF21B	0.029008
ADRB2	0.028970
CHAC1	-0.028772
WISP2	0.028720
FOLR1	-0.028650
IER5	-0.028629
RNF39	-0.028553
ID2	0.028553
RASIP1	-0.028458
USP2	0.028419
HPDL	0.027899
JDP2	0.027887
LUZP1	0.027821
NET1	0.027821
GPR155	0.027738
APLN	-0.027516
GJD4	-0.027493
GABRR1	-0.027300
GSE1	0.027179
PLCD3	0.027054
GPR123	0.026991
CASKIN2	0.026937
GPR179	-0.026764
TAP2	0.026733
CASC5	0.026726
PTX3	-0.026679
CREBL2	0.026676
PYROXD1	0.026534
APOL2	0.026486
TSGA13	0.026471
PIM3	0.026392
EREG	-0.026321
TRIM31	0.026199
SDC4	0.026104
PCMTD1	0.026006
ANKRD66	0.025911
FBXL21	0.025873
HRSP12	0.025823
ESCO1	0.025817
FAM169A	-0.025775
PARP16	0.025622
ACKR3	0.025612
METRNL	0.025521
PRSS22	-0.025517
CDR2	0.025265
HIST1H4I	-0.025242
SHB	0.025228
METTL10	0.025094
PLXNA2	0.025030
NUTM1	0.025025
PTPN1	0.024919
ZNF433	0.024897
HERPUD1	0.024860
CCNL1	0.024854
CYTH4	0.024806
NAB2	0.024765
GBX1	-0.024741
SOCS3	0.024738
TTC30B	-0.024729
FAM43A	0.024702
CERS3	-0.024690
ZNF761	0.024659
RASSF8	0.024632
AFAP1L2	0.024585
MYO16	-0.024554
CENPE	0.024547
STYK1	-0.024517
SMC2	0.024511
TGIF1	-0.024467
ACHE	0.024441
EPHA2	-0.024426
TIE1	-0.024413
MARS2	-0.024383
TPRN	0.024303
ARL4D	0.024272
AHR	-0.024268
EHD4	0.024215
FOSL1	-0.024200
APOF	-0.024182
GDNF	-0.024177
HOXD9	-0.024089
PTPN4	0.024084
EMC2	0.024036
SERTAD1	-0.024002
ACTG2	-0.023945
TRIM63	0.023942
SHPK	0.023938
NIPAL1	0.023883
SFT2D3	-0.023874
GATA3	-0.023838
INSL6	0.023772
IRS1	-0.023732
LUC7L3	0.023726
TRIM24	0.023715
PIK3R5	-0.023689
BLNK	0.023683
LIPT1	-0.023654
C10orf2	0.023625
NOXRED1	-0.023613
CAMK2B	0.023574
PAX5	-0.023551
KLHL21	0.023541
CSF2	-0.023530
L2HGDH	0.023508
CD7	0.023497
CCDC117	0.023229
TGM2	0.023132
SGPL1	-0.023124
THOC2	0.023100
ZFP62	0.023006
C11orf52	0.022948
IRAK2	-0.022937
NHLRC3	0.022923
SMAGP	-0.022923
ALPK1	-0.022911
DUSP6	-0.022909
MEF2A	0.022841
DSTYK	0.022797
TMPRSS11F	0.022699
ZNF664	0.022615
CLEC5A	0.022601
NRN1	-0.022579
CNTLN	0.022564
CRYGB	-0.022544
BAMBI	-0.022541
SHANK3	-0.022541
CCDC57	0.022515
ZNF687	-0.022506
SERINC4	-0.022358
SLURP1	-0.022358
SRGAP1	-0.022353
GPER1	-0.022351
BCL2L11	0.022286
CCDC105	0.022269
SRP19	0.022214
SPIB	0.022194
RPUSD1	-0.022152
DYNLT3	0.022150
ZNF445	0.022128
TNS1	0.022122
DDX28	0.022114
AIM1	-0.022079
COG7	-0.022030
DEPDC7	0.022018
TSPYL2	-0.022010
KIF5C	0.022008
ABCC3	-0.021925
LY96	0.021919
PPIL4	0.021913
VDR	0.021812
PCGF1	-0.021802
CCP110	0.021780
C14orf79	-0.021757
TLR8	0.021739
THBS2	0.021738
EYA2	0.021727
PSORS1C2	-0.021722
ESF1	0.021715
PLG	0.021636
EML4	0.021621
FAP	0.021592
GLMN	0.021577
SULT2B1	-0.021542
SYNPO	0.021510
GOLGA4	0.021501
WDR60	0.021453
PLAUR	-0.021375
ARC	-0.021305
FAIM3	-0.021290
ZER1	0.021286
KCNQ1	-0.021213
ASB12	-0.021141
GSC2	0.021113
HAUS3	0.021106
GPX7	0.021091
LOC100130301	0.021074
TMEM170B	0.021052
KRR1	0.021045
PRIMA1	-0.021032
MLC1	-0.020980
FKBP14	0.020922
C11orf68	-0.020910
CLK1	0.020856
SIGIRR	-0.020800
RNF6	0.020784
NCKAP5	0.020759
C3orf58	-0.020705
MSH4	-0.020688
RARS2	0.020685
HYAL4	0.020684
CXCL10	0.020668
CYP39A1	0.020617
GAREML	-0.020607
ZNF416	-0.020592
TACR3	-0.020583
VAT1	-0.020560
GPBP1	0.020537
FBP1	0.020523
DLX2	-0.020517
ZBTB38	0.020488
RFTN1	-0.020470
PSMA8	-0.020449
RNASE4	-0.020424
C1orf27	0.020407
M1AP	-0.020403
FAM83F	0.020388
GAS2	-0.020370
LYG1	-0.020305
SLC2A6	-0.020304
CADM4	0.020298
THBD	-0.020272
FAM35A	0.020245
LTC4S	-0.020218
YPEL2	0.020202
ZNF469	0.020144
RNF31	-0.020118
HPS5	-0.020096
LCP2	0.020049
ZNF146	-0.020038
P2RY6	0.019995
CBWD1	0.019984
UBE2D4	0.019948
SLC12A2	0.019939
CD2AP	0.019939
ROCK1	0.019935
FCGBP	-0.019882
GFRA4	-0.019862
TENC1	0.019862
FAM129A	0.019813
HSPA2	0.019798
EFHB	-0.019774
HBEGF	-0.019756
CNGA2	-0.019693
MME	-0.019683
RAPSN	-0.019677
DNAJC5B	-0.019675
HCAR1	-0.019671
LYPD4	0.019657
KCNS1	0.019657
C6orf201	-0.019655
HIST1H1C	-0.019623
HFE2	0.019620
TCP11L2	0.019600
KIAA1143	0.019569
MKI67	0.019540
EIF4A2	0.019530
CENPF	0.019522
ANKRD12	0.019512
ZC3H11A	0.019457
TMEM88B	0.019450
PFKFB3	0.019444
UBALD1	-0.019438
MAN1C1	-0.019433
RASA2	0.019418
C9orf173	-0.019408
MCF2	0.019390
PDXP	0.019374
C17orf53	-0.019345
LZTS2	0.019342
RND1	-0.019335
ITGAX	-0.019311
CCRN4L	-0.019269
ZNF354A	0.019252
IFT74	0.019195
USP9Y	-0.019111
ZYG11A	0.019092
UPF3B	0.019076
NFKBIE	-0.019043
ZMIZ1	0.019008
PATL2	0.018995
DGKI	-0.018978
C9orf116	-0.018960
FAM26F	-0.018949
CLK4	0.018938
PPP2R5B	-0.018935
FSCN2	0.018930
THOC5	-0.018917
ACTN2	0.018911
ZC2HC1B	-0.018900
NR2E1	-0.018892
FGF21	-0.018877
ZFP14	-0.018863
PRRX2	-0.018861
ZUFSP	0.018824
UQCRC1	-0.018820
NINJ2	-0.018807
NKPD1	0.018806
C16orf46	0.018801
RSF1	0.018781
C3orf33	0.018775
PIK3R1	0.018762
HNF1A	-0.018729
OXR1	0.018727
SP8	-0.018721
TSPYL1	-0.018695
G6PC3	-0.018680
CEP290	0.018661
SNAI2	-0.018650
PEX26	0.018635
FAM110A	-0.018618
PMEPA1	0.018611
VASN	0.018594
HOXC13	-0.018592
WNT2B	-0.018587
SUPT4H1	0.018576
TULP1	-0.018563
ANPEP	0.018561
BRCA2	0.018553
FKBP3	0.018547
ATG101	0.018544
YTHDC1	0.018541
CSAD	-0.018505
STAG3	0.018469
AMBN	0.018469
NAA15	0.018468
TSNAXIP1	-0.018468
ZC3H3	-0.018466
KIAA1033	0.018455
METTL20	0.018454
CYB5RL	0.018420
NDEL1	0.018414
ZC3H12C	0.018405
TAS1R3	-0.018396
ACY1	-0.018356
CFAP97	0.018348
FAM47E	-0.018334
KERA	0.018315
SMUG1	0.018297
GHRL	-0.018286
SMC4	0.018276
FAM19A3	0.018274
ALKBH1	0.018265
TAC3	0.018261
MTERF	0.018259
DNAJC3	0.018249
ASGR2	0.018193
PTGS1	0.018193
EIF3A	0.018176
BMP4	0.018172
RBMS1	0.018169
PLK5	-0.018159
SLC35C1	0.018112
SAA2-SAA4	-0.018111
PRSS8	-0.018106
PPIG	0.018105
AGXT	-0.018103
TGM4	-0.018069
ATP11C	0.018035
PPM1H	-0.018005
C17orf64	-0.018005
UPK3BL	-0.018000
FAM46B	0.017966
RHAG	0.017948
ATOH8	-0.017948
MYLIP	-0.017926
DUSP13	-0.017916
PEAK1	0.017916
SERPINA10	0.017896
CENPQ	0.017875
DPH1	-0.017856
C3orf62	0.017821
IRX1	-0.017806
CNKSR3	-0.017767
PRMT5	-0.017752
TYW5	0.017746
DCAKD	-0.017740
TRIOBP	0.017726
GLP1R	-0.017710
HYPK	-0.017697
TMEM72	-0.017689
GREB1	0.017675
FAM195B	-0.017663
TFAM	0.017657
PGPEP1	0.017635
KRT7	0.017619
P4HA3	0.017615
CLN6	-0.017603
TMF1	0.017601
UBE2L6	0.017593
FLCN	-0.017591
SEPT2	0.017585
HIST1H2BJ	-0.017544
SPO11	0.017541
FAM229B	0.017526
PLK2	-0.017524
B4GALT5	0.017514
KIRREL3	-0.017511
TNFSF8	-0.017506
LHB	-0.017500
SARNP	0.017497
TRAF3IP3	-0.017473
CAPN1	-0.017463
RBPJ	-0.017459
SEMA4G	-0.017454
KCNH7	0.017448
RBM20	0.017436
ZSWIM5	-0.017436
VAC14	-0.017433
PTRF	-0.017417
POLR3G	0.017395
ARTN	-0.017383
CTXN3	-0.017373
NPR2	0.017369
MS4A10	-0.017369
DDX19A	-0.017367
DBP	-0.017345
SMOC1	-0.017340
KLF6	-0.017315
SMC3	0.017315
NME8	0.017307
SPNS1	-0.017306
KLHDC7A	-0.017305
NEMF	0.017297