!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	leptin
!ligand_id	PubChem CID: 90470904
!cell_type	liver
!organism	mouse
!end_metadata
OAT	-0.230506
HP	0.187931
FADS1	0.187912
GNMT	-0.179597
TF	-0.170682
GPX1	-0.165908
UBC	-0.153594
INMT	0.149121
APOA1	0.135068
RETSAT	-0.132442
ATP5B	-0.130076
ALDOB	-0.129171
MAT1A	-0.126324
FDPS	0.115639
GSTM1	-0.112408
HPX	0.111655
ERRFI1	0.111047
G6PC	-0.110365
TTR	-0.107361
HMGCS2	-0.105241
ALAS1	0.104115
CA3	0.102240
CYP2E1	-0.099558
KHK	-0.099157
RPS20	0.096114
DBP	0.095684
RPL3	0.092335
ACLY	-0.091864
PON1	-0.090619
RPS12	0.090117
NUDT7	0.090002
TMBIM6	-0.089302
IFITM3	0.087185
GAPDH	-0.086841
EPHX1	-0.086778
AMBP	-0.082432
APLP2	-0.078078
MGST1	-0.076150
ADH1C	0.075757
CES1	-0.073648
UROC1	-0.073285
VTN	0.072829
RPS2	-0.068022
HIBADH	-0.067346
HMGCS1	-0.066001
TUBA1B	-0.065909
SOD2	-0.064907
WBP1L	-0.064905
HAO1	0.064535
P4HB	-0.063998
HIST1H1C	0.063844
CLU	0.063823
NDUFA10	-0.063283
KYNU	-0.062782
FBP1	-0.061497
APOA4	0.061241
UGT3A1	-0.060891
NNMT	-0.060504
GOT2	-0.060120
PTTG1IP	-0.059700
GLDC	-0.058764
ALDH3A2	-0.058695
ARG1	-0.058287
CDO1	0.058278
FTH1	-0.055787
MSMO1	0.054203
PTPLAD1	0.054093
RPL10	0.053422
ABHD14B	0.052382
ELOVL5	0.052348
LDHA	-0.051902
CYP17A1	-0.051809
CYP8B1	-0.050625
GSTP1	0.050339
ABCB4	-0.049891
RPL28	0.049696
APOA2	-0.049401
GSTA5	-0.049058
BAG1	-0.049023
LRG1	-0.048869
ALDH1A1	-0.047590
ABCG5	0.047026
TTPA	-0.046594
AHSG	-0.046449
STARD10	-0.046228
G0S2	0.046185
AZGP1	-0.046120
DAK	-0.045699
NIPSNAP1	-0.045579
KRT8	-0.045492
ACAA1	0.045205
RPS21	0.045087
GSTA3	-0.044820
ATP1A1	-0.044374
GCH1	-0.044283
SLC27A2	0.044096
ADK	-0.043802
CHCHD10	-0.043523
NPM1	0.043368
UQCRHL	0.042973
VCP	-0.042530
NDUFB8	-0.042496
ACSL1	0.042153
WBP2	-0.041704
RPS24	0.041335
EBP	0.040437
CHPT1	-0.040314
ACACA	-0.040063
THRSP	-0.039764
CAT	-0.039733
ITIH4	0.039599
SLC25A47	-0.039134
INSIG2	-0.038971
RARRES2	0.038956
SERPING1	0.038713
AACS	0.038590
SEPP1	-0.038569
RPS4Y1	0.038545
RPL9	0.037708
NME1	-0.037638
ISCU	-0.037142
UPP2	0.037011
EIF5	-0.036969
ACSS2	0.036369
ELOVL6	-0.036230
BGN	0.036066
RPS16	0.035942
CPS1	-0.035810
AQP8	0.035201
CYP4F12	0.035039
AMFR	-0.034999
ATF5	-0.034249
CBR1	-0.034244
CD164	-0.034049
AQP9	0.034001
APOE	-0.033952
HSPA8	0.033470
CYP4A22	0.033225
GPT2	-0.032856
ORMDL3	-0.032613
ADIPOR2	-0.032523
ANXA2	-0.032269
CES3	0.032131
SPP2	0.032018
NDUFS6	-0.031985
SLC25A5	0.031611
CD1D	-0.031609
NREP	0.031427
MOCS2	-0.031333
XBP1	0.030734
IFITM2	0.030384
CYB5B	-0.030133
SDS	-0.029786
F2R	0.029777
TALDO1	-0.029770
ACOX2	-0.029740
NDUFA13	-0.029620
LRRC28	-0.029612
LAPTM5	0.029243
GRHPR	0.029196
RPS9	0.029096
HINT2	0.029078
ME1	-0.029074
SQSTM1	-0.028925
DBI	-0.028892
RPS14	0.028746
CYP4A11	-0.028714
PPIF	0.028681
EDF1	-0.028645
ABCG8	0.028105
RPS17	0.027844
GM2A	-0.027789
HTATIP2	-0.027782
EIF4A2	0.027745
RPL35	0.027500
TUBB4B	-0.027281
FAM102A	0.027212
UQCRC2	0.027183
FGG	-0.027162
RNASE4	0.027121
DMBT1	-0.026975
PSMD4	-0.026908
NDUFA6	0.026790
GPT	0.026775
GLYAT	0.026559
RPL37A	0.026325
CYP27A1	0.026264
PRELP	0.026105
PLIN2	0.026083
ACADM	-0.025988
CERS2	-0.025982
C2	0.025686
RBP4	0.025610
CEBPB	-0.025306
GRINA	0.025214
RPS19	0.025137
PRDX4	0.025131
PGP	-0.025026
PSMA4	-0.024980
RPL18	0.024813
BSCL2	-0.024812
ABCD3	-0.024690
PPM1K	0.024687
COX7A2L	0.024604
EI24	-0.024521
RPL12	0.024251
HSD3B7	0.024051
UROD	0.023933
FADS2	0.023900
RPL38	0.023868
SPP1	0.023752
EBPL	0.023602
AKR1A1	-0.023502
ASGR1	-0.023438
TANGO2	0.023304
DUSP1	0.023299
BHMT	-0.023252
ABHD17A	-0.023197
CYP2B6	-0.023161
TMEM176B	0.023110
LPL	0.023094
C19orf66	-0.023077
BHLHE40	0.022848
SFXN1	0.022835
UBL5	0.022620
C19orf80	0.022553
CFD	0.022456
QDPR	0.022284
MAN2A1	-0.022086
CD74	0.021921
SSR4	0.021819
RPL37	0.021777
HRSP12	-0.021672
AGPAT2	-0.021642
RPL27	0.021616
SLC27A5	-0.021582
CLEC4G	0.021548
PPA1	-0.021519
FMO3	-0.021514
C10orf10	-0.021409
UQCR10	-0.021329
ACSL5	0.021267
HNF4A	-0.021073
MCM10	0.020967
EMC10	-0.020674
ATP5G3	-0.020643
SCP2	0.020573
HLA-E	0.020571
AES	-0.020524
RELN	0.020499
SLC22A1	-0.020456
TMBIM4	-0.020402
RPL39	0.020394
LCAT	-0.020195
FCGRT	0.020178
GSTZ1	0.020077
PQLC1	-0.019785
PAQR7	0.019705
LGALS1	-0.019572
BAAT	-0.019458
FITM2	0.019415
IDH1	0.019321
TMEM205	0.019162
TMEM86A	0.019051
AGT	-0.018968
DAG1	-0.018951
C6orf203	0.018880
ANGPTL4	-0.018799
BTF3	0.018749
ACOT13	0.018723
PPM1B	0.018654
KRTCAP2	0.018650
CIDEA	-0.018625
FH	-0.018529
YPEL3	0.018440
C8A	0.018179
SUDS3	-0.018165
GABARAP	0.018139
ZFYVE21	0.018120
RPS8	0.018057
VSIG4	0.018003
COX6A1	-0.017919
GPC1	0.017900
ZFPM1	-0.017622
RPS6	0.017620
RPL31	0.017611
ARSA	0.017592
OSBPL9	-0.017523
SPOP	-0.017480
PCYT2	0.017469
C11orf24	0.017401
LGALS3	0.017392
GABARAPL1	0.017382
APOM	0.017330
SCD	0.017327
MAGED1	0.017284
GCGR	0.017205
KLHDC2	0.017182
MRAP	-0.017175
C8B	0.017172
C9	-0.017119
STT3B	-0.017102
TSPO	0.017098
DPP7	0.017094
LAMTOR4	0.016964
OSGIN1	-0.016906
PYGL	-0.016896
LYPLA2	0.016870
PLTP	0.016865
RNF10	-0.016843
HSD17B7	0.016837
ACAA2	0.016780
NAT8B	0.016771
HNRNPAB	-0.016756
PROC	0.016714
ATP5D	-0.016713
PPP1R3C	0.016712
TECR	0.016701
RCAN1	-0.016665
SLC25A25	0.016647
HSD11B1	-0.016561
ANG	0.016559
BHMT2	-0.016487
DGAT2	-0.016484
PDZK1	0.016387
NDUFA7	-0.016346
YWHAG	-0.016321
FGL1	-0.016298
TAB2	-0.016227
ATP5C1	0.016207
QPRT	0.016188
SQLE	0.016177
LGMN	0.016174
COX8A	0.016140
UBE2E2	-0.016127
PDIA3	0.016098
FAM134B	-0.016092
SLC46A3	0.015994
SLC9A3R1	0.015985
NADK	-0.015949
SLC6A13	-0.015799
CSTB	0.015777
FKBP8	-0.015776
ATP5G1	-0.015762
SOD1	0.015684
HADHB	0.015677
RPL5	0.015531
MMD2	-0.015414
GLS2	-0.015404
SERPINA1	-0.015402
RPS7	0.015342
EGR1	-0.015247
RPS13	0.015207
CISD1	0.015173
SS18L2	0.015115
CST3	0.015090
ACTB	-0.015032
RNF103	-0.015030
SLC25A15	-0.014866
SUCNR1	0.014829
PRELID1	-0.014829
AXL	0.014804
CTNNA1	0.014783
HLA-DQB1	0.014767
LONP2	0.014717
SIRT3	-0.014687
LYZ	0.014682
FAHD1	0.014663
SYVN1	-0.014637
TGM2	-0.014635
MRPS12	0.014615
REEP6	-0.014584
TBCA	0.014511
FGA	-0.014494
SERPINA3	-0.014483
MRPL12	0.014473
C5	0.014454
NCEH1	0.014445
SPCS1	0.014401
RPS27L	0.014394
CCT4	0.014378
TMEM38B	-0.014306
RGS16	0.014273
EPHX2	0.014247
GDE1	-0.014234
F11	0.014202
TMEM56	0.014198
ZFAND3	-0.014136
COX4I1	-0.014110
MFSD2A	0.014102
MAN2B1	0.014036
S100A10	-0.013931
PPP1CA	-0.013896
HNRNPC	0.013836
DHCR24	-0.013821
LAMP2	-0.013815
SLC5A6	0.013792
NSMF	-0.013774
FGF21	0.013772
SARAF	-0.013760
TMEM97	0.013741
UQCRC1	-0.013594
DUS1L	-0.013578
FAH	0.013522
HP1BP3	0.013517
IRF2	0.013517
SMIM19	0.013467
GRB7	-0.013444
CCBL1	0.013437
NUDT4	-0.013433
HDGF	-0.013421
JTB	-0.013418
PLG	0.013393
ZFP36L1	-0.013391
MBL2	0.013378
APMAP	-0.013338
SLC25A39	-0.013306
ATP6AP1	0.013300
NDUFV2	0.013286
SBK1	-0.013283
C14orf2	-0.013269
AARS	-0.013233
NDUFA4	0.013185
LY6D	-0.013130
GLG1	-0.013089
UGT2B17	0.013047
GLRX	-0.013038
GHR	0.013020
AK2	0.013010
AMY2A	-0.012966
FAM73B	0.012940
IGFBP4	0.012843
HIST1H2BI	-0.012837
TAPT1	-0.012822
C1QC	0.012800
PARVA	-0.012791
CIDEC	0.012682
MLXIPL	-0.012676
CDHR5	-0.012593
TMEM120A	0.012555
CTH	-0.012509
CYP3A5	-0.012495
PRODH2	0.012490
BAG3	-0.012456
BOLA3	-0.012433
TLCD1	0.012425
SAR1B	0.012407
FAM53A	-0.012390
PSENEN	0.012345
HHEX	0.012340
TPI1	0.012251
IGF1	0.012229
GUK1	-0.012226
RPL22	0.012220
ATP5F1	0.012211
CD82	0.012172
BTG1	-0.012167
CYP2F1	-0.012157
VTI1B	-0.012152
CYB5A	0.012107
NT5E	-0.012077
VKORC1	0.012054
AGXT	0.012034
C14orf166	0.012019
NDUFA1	-0.011987
MREG	-0.011983
GUCD1	-0.011969
SOCS2	0.011967
HSD17B4	-0.011967
RPL35A	0.011965
POLDIP2	-0.011948
SMARCA2	0.011935
GCLM	-0.011926
PANK1	0.011910
PLK3	-0.011860
RPS25	0.011844
IGFALS	0.011825
ENTPD4	-0.011781
HSPA9	0.011767
LRTM1	-0.011753
MRPL27	0.011625
MLF2	-0.011622
PNKD	-0.011597
LPAR6	0.011590
SLC6A6	-0.011587
ASS1	0.011571
RNF11	-0.011569
C11orf54	-0.011530
FOXA3	0.011463
CSRP3	0.011352
ANAPC13	0.011288
PAOX	0.011267
UAP1L1	0.011241
PGM1	0.011234
PPP2CB	-0.011222
SLPI	0.011221
USE1	0.011215
SMARCD2	0.011194
FETUB	0.011162
CNPY2	0.011149