!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Monuron
!smiles	CN(C)C(=O)NC1=CC=C(C=C1)Cl
!pubchem_cid	8800
!cell_type	rat proximal renal tubule cell line (NRK-52E), 24h treatment
!organism	rat
!end_metadata
CYP1A1	0.104888
ARG2	0.092727
TRIB3	0.085103
ZC3H6	0.084408
CASP4	0.081380
SLC7A11	0.081344
CHAC1	0.077055
OTUB2	0.076634
SLC7A7	0.074901
NNMT	0.064983
PHLDA1	-0.063903
EOMES	-0.059452
SLC29A1	0.058950
SLC7A5	0.058452
DDIT3	0.058205
CTH	0.057102
COL14A1	-0.056496
TFRC	-0.054393
RUNX1	0.053567
BCAT1	0.053299
CLIC3	0.052911
INHBE	0.052000
TESK2	-0.051013
PDGFRL	0.051005
RRAGD	0.049819
ASNS	0.049688
YPEL4	0.048821
PCDHB15	-0.048506
LMNB2	-0.047502
SERPINE1	0.047266
CRMP1	-0.047132
SLC4A7	0.046846
CA1	-0.046505
SLC22A18	0.046384
DHODH	-0.046094
ADHFE1	0.045971
C1QTNF5	0.045943
ECHDC3	0.045859
BEND6	0.045679
SEC16B	0.045512
MGST2	0.045237
TGIF2	-0.045095
RIBC1	0.044903
GLRB	0.044390
DBP	0.043821
STEAP3	0.043708
ATF3	0.043591
SEMA3B	0.043410
CCDC106	0.042988
STYXL1	0.042837
RNASEL	0.042575
FGF21	0.042266
CENPW	-0.041978
PYCR1	0.041760
SPAG4	0.041684
PUSL1	0.041620
SRSF2	-0.041370
MTHFD2	0.041331
NUDT18	0.041301
HEY1	0.041267
CTF1	-0.041236
HEXIM1	-0.041139
TM6SF1	0.041082
MAMDC2	0.040692
PRMT6	0.040456
THEM4	0.040152
DUSP6	-0.039939
TMEFF1	0.039653
DACT2	-0.039561
VLDLR	0.039553
BMP2	-0.039478
DENND4A	0.039468
UAP1L1	0.039356
ACTA1	0.039085
HSPA4	-0.038789
NHEJ1	0.038715
SLC3A2	0.038541
PSMB8	0.038525
TRPM4	0.038459
MRAS	0.038021
PTGS2	0.037958
CTBS	0.037864
CYS1	0.037753
ATP6V1C2	0.037734
NRN1	0.037724
PCK2	0.037686
LIAS	0.037610
TMEM222	-0.037172
SRSF6	-0.036972
EPS8	0.036763
PURG	0.036747
UBE2K	-0.036544
SRSF1	-0.036349
TMEM62	0.036279
PGAM2	0.036160
DYRK3	-0.036060
PHF7	0.036031
OPN3	0.035941
SNN	-0.035823
MFSD2A	-0.035467
INVS	0.035301
STBD1	0.035103
NETO2	-0.035028
ZNF775	0.034792
HIGD1A	-0.034763
FBXL4	0.034636
PCDHB11	-0.034402
HMGCS2	0.034385
SARS	0.034364
GPT2	0.034281
SAYSD1	0.034239
KCNIP3	0.034210
ITGA2B	0.034175
CD44	0.034085
DHRS1	-0.034003
N4BP2L1	0.033987
ISG15	-0.033720
UTP14A	-0.033707
TCEB1	-0.033661
TCEA3	0.033399
ANKRD37	-0.033391
MARS	0.033352
CLSPN	-0.033200
KCNJ14	-0.033183
CCNE1	-0.033157
PER2	0.032914
TEK	-0.032824
FBXO15	0.032789
TSSC1	-0.032786
PTPLAD2	0.032716
RFXANK	0.032712
PUS7L	0.032691
NUDT6	0.032682
RRP8	-0.032669
SLC7A9	-0.032619
CELF5	-0.032563
FGGY	0.032562
ALDH3B1	0.032560
IQCC	0.032518
SFPQ	-0.032489
RHBDF2	0.032399
SLC6A9	0.032394
USP11	0.032288
CBR4	0.032213
EVA1A	-0.031961
PPP1R15A	0.031926
CEBPG	0.031896
SERPINB1	0.031891
SSPN	0.031820
GRB10	0.031740
ARFGAP1	-0.031597
HNRNPA2B1	-0.031523
OAS1	-0.031509
SLC25A33	0.031454
CCDC62	0.031400
ASF1B	-0.031229
SLC50A1	0.031220
PLA2G4A	0.031176
TMEM50B	-0.031018
CDA	0.030970
COL8A2	0.030858
THNSL2	0.030816
NFIL3	0.030642
OSBPL6	0.030595
SNTG2	-0.030551
TCEAL1	0.030544
TRAPPC2	-0.030526
JDP2	0.030468
KLHDC1	0.030432
FMNL3	-0.030378
DHX58	0.030377
CDS2	0.030365
KCNS3	0.030296
DEPDC1B	-0.030101
KLF9	0.030083
ZFAND2A	-0.029843
DHX9	-0.029784
HSD17B7	-0.029739
NUBPL	0.029715
SHBG	0.029704
S1PR5	-0.029686
PRPF4B	-0.029596
POPDC2	0.029534
DHRS4	-0.029501
RHEBL1	0.029492
KLHL5	0.029466
SLC10A4	-0.029453
HERPUD1	0.029444
FAM13B	-0.029424
NOTCH1	-0.029336
PDLIM2	0.029311
LAMA3	0.029203
SMARCA1	0.029172
SAMHD1	-0.029129
FAM101B	-0.029121
GATAD2A	-0.028975
SRSF3	-0.028959
TNNI3	0.028914
SH2D4A	0.028910
SNAPC5	0.028782
AKR1B10	0.028771
CXCL2	-0.028757
FBXO9	-0.028735
EXOSC5	-0.028641
SCN1B	0.028602
FASN	-0.028374
ACAD11	0.028342
MMACHC	0.028328
CCND2	0.028310
MCM7	-0.028216
SLC16A6	0.028130
COQ10A	0.028117
SRD5A1	-0.028063
CCDC159	0.028034
FBXO4	0.028026
CLYBL	0.028009
GINS3	-0.027911
RRP12	-0.027830
DTWD1	0.027792
GNG8	0.027776
CDKL3	0.027663
DDX11	-0.027641
GADD45A	0.027238
CCNYL1	-0.027206
CASC1	0.027174
EMP2	0.027154
TARDBP	-0.027108
LRRC8D	0.027034
ARL2	0.026963
CREB3L1	0.026920
NAT10	-0.026842
MYL9	0.026835
TIMM10B	-0.026821
DUSP1	-0.026794
PRSS45	-0.026788
LYPD8	0.026676
VEGFB	0.026663
FZD3	-0.026634
COMP	0.026613
METTL22	0.026555
FASTKD5	-0.026531
DONSON	-0.026476
SESN2	0.026439
NAGLU	0.026352
SFXN1	0.026313
ZNF524	0.026276
ATF5	0.026231
PTRHD1	-0.026224
DUSP19	0.026176
PHB	-0.026165
TINF2	0.026155
ARHGEF9	0.026067
IKZF2	0.026057
PPP1R35	0.026053
HOXC5	-0.026006
CDC42EP2	-0.025995
CCDC17	0.025932
SHMT2	0.025919
MIB2	0.025885
SULT1C2	-0.025805
RAD52	0.025782
GFM2	0.025761
EMC8	-0.025753
AOX1	0.025715
CENPE	-0.025709
CDV3	0.025646
SCRN1	-0.025540
LYRM1	0.025469
ALKBH3	0.025457
COL1A2	0.025455
HDDC3	0.025433
FEN1	-0.025414
GNB5	0.025301
SLC2A6	0.025253
GSTA5	0.025243
SF3A1	-0.025193
BPHL	0.025180
AP1B1	-0.025166
APTX	0.025129
ZFAND1	0.025116
WDR6	-0.025103
SP140	0.025001
HEBP1	0.024926
EPRS	0.024894
TATDN2	-0.024886
MMP28	0.024883
LANCL2	-0.024798
ALDH18A1	0.024723
ATF4	0.024705
ERCC6L	-0.024667
AP5S1	0.024659
RING1	0.024610
ADAM9	0.024581
C1QTNF1	0.024547
DUS2	0.024544
MON1B	-0.024535
PADI3	0.024516
WRAP73	-0.024443
TMCO6	0.024425
NDC80	-0.024407
KTI12	-0.024365
NOL12	-0.024341
TRIP13	-0.024338
YIPF2	0.024331
GPM6A	0.024315
HAGHL	0.024306
RBMX	-0.024284
SLC4A2	-0.024268
MPND	-0.024248
SEPN1	0.024248
FAHD2B	0.024236
LRRC1	-0.024219
SMAGP	0.024138
CAPRIN2	0.024005
CRABP2	0.023998
TPRN	-0.023992
DZIP1	-0.023972
LAMB3	0.023947
TMEM180	0.023943
ZFR2	0.023925
MANEA	0.023899
SLPI	0.023885
DDX46	-0.023813
CRY1	0.023773
LYPLAL1	0.023752
POC5	0.023737
RHOBTB1	0.023712
EXOG	-0.023702
POLA2	-0.023666
TSR2	-0.023662
KLF15	0.023659
TMEM204	0.023647
GID4	0.023612
MYO9A	0.023597
PDE11A	0.023577
PCSK4	0.023557
MTHFD1L	0.023549
PREPL	0.023537
FBXL8	0.023494
NR1D2	0.023472
SPON2	0.023466
HIST2H3A	-0.023348
NTPCR	0.023332
MLF1	-0.023328
KCND1	0.023327
RFC3	-0.023290
AMIGO2	-0.023280
TIMP3	0.023266
CYP2U1	0.023241
RIMKLA	-0.023218
ADAMTSL4	0.023158
NARF	-0.023148
AMPD3	0.023128
MGAT1	-0.023110
ATG14	0.023053
RAMP2	0.023031
APBB3	-0.023008
CA11	0.022981
FAM35A	0.022954
PDK1	-0.022926
SQLE	-0.022901
EPPIN	-0.022894
CCDC37	0.022881
VASH2	0.022859
CDCA3	-0.022831
MBD5	-0.022794
PHLDA2	0.022780
NCLN	-0.022778
EDN1	-0.022757
KNTC1	-0.022745
ADAMTS10	-0.022733
GCA	-0.022732
SFI1	-0.022721
MXD3	-0.022635
PIH1D2	-0.022624
POLG2	0.022621
FAHD1	-0.022615
GXYLT1	-0.022590
FBXL15	-0.022588
TATDN3	0.022580
TPI1	-0.022532
SMIM1	0.022523
TNNC1	0.022487
FAM83D	-0.022476
PET100	-0.022460
TAOK2	-0.022404
PROSER2	0.022404
GALM	0.022360
TGFBR2	0.022345
GARS	0.022316
SNRPB	-0.022311
CAB39L	0.022298
DDX51	-0.022285
ACTR5	-0.022280
FXYD5	0.022270
ACAD10	0.022265
NR1D1	0.022255
AXIN2	-0.022228
TPRKB	-0.022226
TMEM97	-0.022165
MXD4	-0.022159
CCDC92	-0.022154
FAM46C	-0.022146
TRDMT1	0.022134
ATG2A	-0.022129
TTC33	-0.022125
EREG	0.022054
HN1	-0.022025
PEX11G	0.022019
DYNLRB2	0.022016
GTPBP2	0.022006
ATG10	0.022006
USP2	0.021996
VEGFA	0.021987
LARS	0.021984
RFT1	0.021940
MDFIC	0.021925
SPIN1	0.021917
HSBP1	-0.021882
ANGPTL2	0.021830
TMEM86A	0.021821
ZNF597	0.021813
HINT3	0.021812
NAA40	-0.021804
FAM222B	-0.021769
ANKRD24	0.021744
XPA	0.021741
MIOS	-0.021731
ESPL1	-0.021709
ZCCHC8	0.021703
SIAH2	0.021679
TGFB1	0.021658
CDADC1	-0.021651
DES	0.021642
SLC43A2	0.021622
MICALL2	0.021620
MRPL49	-0.021616
CDCA7	-0.021588
COTL1	-0.021524
VAMP4	0.021524
TTC22	-0.021484
DCP1B	0.021442
FADD	-0.021440
IL17RC	0.021439
OSR2	-0.021439
LDHA	-0.021434
WARS	0.021406
SLC12A8	0.021400
CC2D2A	0.021340
HAPLN3	0.021335
NASP	-0.021300
OXLD1	0.021288
EPHX2	0.021282
ADCY4	0.021229
SNCAIP	0.021226
ABCG4	0.021222
DOCK6	0.021214
SLC38A9	0.021193
ETV5	0.021182
CTTNBP2	-0.021165
LPHN1	-0.021153
WDR4	-0.021144
CMTM3	-0.021136
MAP2	0.021122
DNAJA1	-0.021118
TCTEX1D2	0.021070
EIF4EBP1	0.021064
PTRH1	0.021030
UPK1B	0.021007
ARHGAP35	-0.020990
POLR1E	-0.020982
ZKSCAN1	0.020980
PVR	-0.020971
GPR56	0.020970
AGTRAP	0.020966
PRPF40B	0.020930
CHAF1A	-0.020892
ISG20	0.020888
TWF2	-0.020859
TSLP	-0.020858
PIK3R3	-0.020820
RRM2	-0.020809
CAV2	0.020804
TMEM256	0.020703
FNIP1	0.020700
DFFB	-0.020641
SZRD1	-0.020638
NCAPH	-0.020633
IMMP2L	0.020620
CCNF	-0.020617
STAT5A	-0.020607
RAB9B	0.020579
ZC3H8	0.020577
FXYD1	0.020563
NFYC	-0.020562
RELL2	0.020535
LYSMD1	0.020532
MR1	0.020512
STRADB	0.020508
FAM102B	-0.020505