!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	angiotensin II
!smiles	CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N
!pubchem_cid	172198
!cell_type	Heart (Wild Type)
!organism	mouse
!end_metadata
ATF3	-0.098105
EGR2	-0.086752
OTUD1	-0.084053
FOS	-0.080833
BTG2	-0.076229
EGR1	-0.072263
CCL13	-0.070482
POSTN	0.068446
SOCS3	-0.065119
ADAMTS1	-0.064414
NOP58	-0.060023
MFAP4	0.059872
THBS1	-0.059086
CILP	0.058155
S100A9	-0.055151
IRS2	-0.052848
EGR3	-0.052765
ERRFI1	-0.050491
NR4A1	-0.050312
SFRP2	0.050008
MFAP5	0.049374
HBEGF	-0.049103
PDK4	-0.048802
ASPN	0.048617
FIBIN	0.048008
COL1A1	0.047946
ABRA	-0.047738
FAM46A	-0.047398
XIRP1	-0.047243
APOLD1	-0.047177
NRN1	-0.046667
ISLR	0.046112
GADD45G	-0.045751
COMP	0.044588
AMY2A	-0.044249
TOX3	-0.044110
IFRD1	-0.043897
S100A8	-0.043505
RBP1	0.041720
LRP5	0.041413
PIRT	-0.041352
CTHRC1	0.040607
COL3A1	0.040006
PRMT1	-0.039685
LMCD1	-0.039445
SERPINF1	0.039239
SERPINB1	0.038936
COL11A1	0.037499
SLC38A4	-0.036951
RNF115	-0.036938
BGN	0.036224
C10orf107	-0.036057
NEB	-0.035666
TMPRSS13	-0.035517
PPM1H	-0.035486
CH25H	-0.035318
COL1A2	0.035246
COL5A2	0.034933
C1QTNF3	0.034881
SERPINE1	-0.034813
CRLF1	0.034553
LUM	0.034531
MMP2	0.034323
LTBP2	0.034259
LECT1	-0.034128
PAMR1	0.034036
TNFRSF12A	-0.033886
NTS	-0.033794
DMPK	0.033737
JUNB	-0.033461
DKK3	0.033160
FOSL2	-0.033095
DCT	-0.032910
FPR2	-0.032879
NDRG4	0.032352
ICAM1	-0.032181
FSTL1	0.032116
MUM1L1	-0.032026
COL6A2	0.031936
PPP1R3B	-0.031767
AHNAK2	0.031149
NREP	0.030996
RAB5C	0.030415
MGP	0.030232
CES1	-0.029971
CDH5	0.029873
SCIN	-0.029865
COL8A2	0.029810
CSRNP1	-0.029792
ZFP36	-0.029604
CCL2	-0.029514
COL8A1	0.029470
COL14A1	0.029452
FLNC	-0.029382
IER2	-0.029088
ASB5	-0.028947
DNAJC7	-0.028737
MAP2K6	0.028693
ADAMTSL2	0.028629
VIM	0.028472
RYR2	0.028410
AS3MT	-0.028343
TMOD4	-0.028341
KCNV2	-0.028316
PQLC3	0.028305
HSPA1L	-0.027958
COL6A1	0.027858
SRPX2	0.027800
IRGM	-0.027759
GAS2L3	-0.027666
MEST	0.027645
IER5	-0.027588
CCDC80	0.027585
ARRDC3	-0.027507
C11orf96	-0.027466
CCL11	-0.027450
RAB20	-0.027415
FXYD6	0.027354
RRS1	-0.027351
GLO1	-0.027341
SYT3	0.027290
OLFML3	0.027181
IGFALS	-0.027093
NFKBIZ	-0.027042
QPCT	0.026936
CCNL1	-0.026927
CTPS1	-0.026912
PDPK1	-0.026826
BDNF	-0.026803
TMX1	-0.026802
ANO10	-0.026743
CYR61	-0.026732
JUN	-0.026584
CFH	0.026524
PCDHB14	-0.026400
MYOT	-0.026356
SLC10A6	-0.026299
PPRC1	-0.026225
NFIL3	-0.026163
RRAS2	-0.026074
SEMA4C	-0.026071
DNAJB1	-0.025989
C14orf37	-0.025913
PCOLCE	0.025894
LRRC17	0.025768
AMD1	-0.025767
KLHL40	-0.025764
COL15A1	0.025690
MAP3K1	-0.025675
ATAD3A	-0.025585
NUAK1	-0.025499
TIPARP	-0.025491
CPXM1	0.025386
IRX3	-0.025318
PLSCR1	-0.025310
PTN	0.025294
SCN1B	0.025267
G0S2	-0.025225
CD300LG	0.025224
NOX4	0.025153
FBXW7	-0.025057
THBS3	0.025005
LOXL1	0.024955
EDN1	-0.024893
IGF2BP2	-0.024756
PSAP	-0.024736
SLC31A1	-0.024708
PTBP2	-0.024690
PDGFRL	0.024670
LTBP4	0.024653
AGPAT9	-0.024615
ITGBL1	0.024533
ZNF770	-0.024434
MXRA8	0.024417
RND3	-0.024351
MAFF	-0.024338
PTPN4	-0.024317
CMTM8	-0.024309
PFAS	-0.024299
MAPK4	-0.024246
SAP30	-0.024204
CCDC146	-0.024189
RRP15	-0.024121
SYNPO2L	-0.024084
CD248	0.024025
C9orf69	-0.023980
ISG20L2	-0.023930
COL5A1	0.023900
TMEM71	-0.023871
INPP4B	-0.023855
APLNR	0.023809
PFKFB1	-0.023737
MAT2A	-0.023641
KDR	-0.023615
PDLIM2	0.023601
HELZ2	-0.023599
HCK	-0.023559
KPNA2	-0.023506
PRPF19	-0.023477
RCAN1	-0.023451
TAB3	-0.023420
ACE	0.023415
LOXL3	0.023399
RGCC	-0.023355
ECM1	0.023308
TMEM128	-0.023275
MALT1	-0.023268
ASB4	-0.023196
KLF6	-0.023187
SPSB4	-0.023178
RAMP2	0.023098
UAP1	-0.023072
ADCY7	0.023040
LRRFIP1	-0.023022
FEM1B	-0.023002
NCEH1	-0.022948
WSB1	-0.022938
PER1	-0.022902
AKAP12	-0.022902
SLC22A3	-0.022854
HTRA4	0.022843
CERK	-0.022789
NPPA	0.022763
TAF3	-0.022666
SNRNP40	-0.022665
EREG	-0.022619
GCH1	-0.022540
MATN2	0.022534
CDKN1A	-0.022453
AZIN1	-0.022410
CAAP1	-0.022404
HAL	-0.022397
ARID5A	-0.022360
ZNF827	-0.022337
CRY1	-0.022247
EFEMP1	-0.022208
MRC2	0.022202
P2RY2	-0.022085
CLDN12	-0.022035
AGO2	-0.022014
ALDH1A2	-0.022001
ADAMTS9	-0.021997
SLC12A5	-0.021990
TNNT3	0.021984
PALM	0.021968
GPR3	0.021873
POLR2A	0.021841
ARHGAP10	0.021824
ANPEP	0.021818
PRELP	0.021771
FITM2	-0.021741
PPIC	0.021733
TREML1	0.021721
SPARC	0.021716
PHKA1	-0.021712
SCGB3A1	-0.021678
AP4E1	-0.021672
IER3	-0.021642
MRPS34	-0.021613
DUSP27	-0.021607
TMEM119	0.021583
USP28	-0.021548
LAMTOR2	-0.021527
TCAIM	-0.021487
USPL1	-0.021358
CD34	0.021321
RASL11B	-0.021316
DVL3	0.021296
KRT72	0.021276
CTSK	0.021261
KLHL41	-0.021258
NCKAP5L	0.021250
HIST1H2BJ	-0.021234
PLEKHA8	-0.021224
PKDCC	-0.021169
SFRP1	0.021161
EVA1A	-0.021085
TIMP1	-0.021061
AHRR	-0.021020
CDR2	-0.020966
HSPG2	0.020952
LMX1A	0.020944
PPP1R15A	-0.020919
PYCR1	0.020896
NRTN	0.020885
FEM1C	-0.020877
ALPI	0.020871
ZNF330	-0.020868
SDC4	-0.020798
BIRC2	-0.020785
XRCC5	-0.020779
DDIT4	0.020778
PSCA	0.020771
PIK3IP1	0.020707
CHAC2	-0.020691
MDK	0.020626
FAM49B	-0.020592
GPX3	0.020572
C14orf159	-0.020533
COX4I2	0.020481
ANKRD2	-0.020466
SMIM3	-0.020447
VSIG4	0.020400
MUC15	0.020393
SRSF3	-0.020390
TMEM47	-0.020373
PIK3R3	-0.020368
B3GNT9	0.020355
TNFAIP6	-0.020330
IFT74	0.020311
MAZ	0.020286
SSC5D	0.020281
PHLDA1	-0.020281
CRIP1	0.020244
KCNA5	-0.020218
C11orf52	-0.020213
RASL10A	0.020207
CLIP3	0.020200
FRMD4A	-0.020197
CEP250	0.020169
ASB14	-0.020165
ALDH5A1	-0.020164
FN1	0.020153
HSD11B1	-0.020151
TDG	-0.020119
BCKDHA	-0.020095
TMEM237	0.020093
BRIX1	-0.020048
ACTN1	0.020036
LSG1	-0.020013
NEFH	0.020010
LARP4	-0.020008
SCUBE2	-0.019991
CECR2	-0.019981
REL	-0.019975
MUC5AC	0.019970
MLXIP	-0.019933
ZFYVE16	-0.019930
KIAA1551	-0.019929
IGFBP4	0.019879
ZBTB16	0.019872
C4orf27	-0.019846
BAI2	0.019830
NUPR1	0.019804
MSL2	-0.019773
PDCD11	-0.019765
SLC20A1	-0.019740
KIAA1614	-0.019684
GRID2IP	0.019666
KLC2	0.019663
TAF1A	-0.019660
YIPF7	-0.019625
CTGF	-0.019600
IFT81	-0.019561
TMEM126B	0.019487
FBP2	-0.019476
PICALM	-0.019474
ARMCX6	0.019445
NUDT1	-0.019436
RDH13	-0.019418
LOXL2	0.019403
WDR3	-0.019361
CNTN5	-0.019329
ATP6V1G2	0.019311
SLC38A2	-0.019306
KIF20A	0.019299
HIST1H4I	-0.019268
ENPP1	0.019252
ILF2	-0.019242
KLF7	-0.019239
DBT	-0.019232
NUP98	-0.019231
CSNK1G3	-0.019205
CD300C	0.019201
FAH	-0.019169
ECH1	-0.019154
SAMD14	0.019129
SLC7A1	-0.019115
IL18R1	-0.019112
MIER3	-0.019107
UBA2	-0.019103
DUSP1	-0.019089
INMT	0.019075
PTPLAD2	0.019042
TSTD2	-0.019040
GPSM3	0.019037
AP2A1	0.019025
UCK2	-0.019022
C3orf43	-0.019021
ECSCR	-0.019013
SLC3A2	-0.018968
TMEM213	0.018958
MICAL2	0.018947
PLEKHF1	0.018936
OC90	0.018932
ZBTB11	-0.018926
ZNF438	-0.018904
FICD	-0.018886
MAOB	-0.018847
SIRT1	-0.018806
FAM26E	-0.018777
OLFML1	0.018747
ENAH	-0.018724
C1QC	0.018719
CHD7	-0.018710
SLC22A23	-0.018704
BTNL9	-0.018703
MYC	-0.018698
NAA25	-0.018658
EBF2	0.018645
FAM217B	-0.018636
ORMDL1	-0.018602
LGALS3BP	0.018584
RRP12	-0.018571
PPWD1	-0.018564
ZNF335	-0.018561
FUBP3	-0.018547
NDUFAF4	-0.018486
PPP2CA	-0.018457
SPRR1A	0.018447
CDK8	-0.018430
ZMYM1	-0.018427
STK32A	0.018407
HP	-0.018407
MIEF2	-0.018390
SRP19	-0.018374
THEM6	0.018341
PNP	-0.018328
PLIN5	-0.018307
SPR	0.018299
TGFB3	0.018294
CENPJ	-0.018294
BLNK	-0.018272
SPATA13	-0.018259
EML3	-0.018256
PKP4	-0.018249
KIAA1377	0.018243
SLC25A40	-0.018232
AMPD3	-0.018230
CALR3	-0.018217
PLXNA2	-0.018149
CYGB	0.018141
WDR90	0.018114
DECR1	-0.018110
KBTBD3	-0.018088
CCDC115	-0.018086
RNASE4	0.018086
SHB	-0.018077
NIT2	-0.018072
CD9	0.018065
RNF44	-0.018056
TGIF1	0.018048
MAP3K5	-0.017983
PAQR9	-0.017975
PLAUR	-0.017949
PRRG3	0.017921
SYNCRIP	-0.017875
CHORDC1	-0.017855
COQ7	-0.017850
AFF3	0.017841
C20orf141	0.017838
MFAP2	0.017799
ADAMTS2	0.017795
SLC9A6	-0.017792
TSC22D2	-0.017776
FAP	0.017767
PEX12	-0.017763
TMEM86A	0.017713
DICER1	-0.017704
SLC12A2	-0.017677
RETSAT	-0.017674
KCTD6	-0.017668
LRRC8A	-0.017663
SPACA3	0.017659
BHLHB9	-0.017654
RBM34	-0.017649
C4orf29	-0.017640
TMEM136	-0.017639
NTSR1	0.017602
EIF1AX	-0.017561
SERTAD4	0.017550
ZBED5	0.017544
CRYZ	-0.017527
ZNF653	-0.017516
PPTC7	-0.017497
GIMAP6	-0.017483
MRO	0.017475
PDE4DIP	-0.017466
TSR1	-0.017447
TMEM245	-0.017432
TRAPPC3	-0.017430
CBX8	0.017429
CXCR4	0.017419
SRPX	0.017415
ARHGAP44	-0.017415
THPO	0.017412
CYTIP	-0.017403
CDK1	0.017393
ALPK3	-0.017392
MMD	-0.017391