!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	cocaine
!smiles	CN1C2CCC1C(C(C2)OC(=O)C3=CC=CC=C3)C(=O)OC
!pubchem_cid	446220
!cell_type	midbrain
!organism	human
!end_metadata
SERPINA3	0.218080
MT1X	-0.162763
JUND	0.160381
PTGDS	-0.141124
FAM107A	-0.131338
HSPA1B	0.109792
TPT1	0.104651
RNASET2	0.102644
PVALB	-0.102289
CALM3	-0.100927
SARAF	0.096566
MGST3	-0.094985
FOS	0.093316
PJA2	0.093009
APOE	0.092506
ALDOC	-0.089022
GFAP	0.087657
HSPA1A	0.086151
GSTM2	0.085291
RPS26P11	0.081863
MTURN	-0.080352
RPS25	0.078827
BCAS1	-0.077073
ZNF486	0.075904
RPL38	0.075072
COX5B	-0.074253
SNAR-A1	-0.073541
RPS11	0.071092
SERPINE2	0.070904
KIF5C	-0.069418
DYNLL1	-0.068660
DPYSL2	0.068619
RGCC	-0.068612
NPC2	0.068538
MBP	-0.066787
GSTO1	-0.066786
AHCYL1	0.066746
CHCHD2	0.066375
CALM1	-0.065720
GHITM	-0.065417
GAPDH	-0.065067
JUN	0.064200
GSTM1	0.064166
ATP6V1B2	-0.063873
CA2	-0.063051
MT1A	-0.062727
GPX4	-0.062486
HLA-DRA	0.062444
APOD	-0.061954
NDRG2	-0.061941
CD81	0.061772
PCP4	-0.061177
ATP6V0E2	0.059999
TMEM144	-0.059841
RPL24	0.058994
SCD	0.058465
OLIG1	-0.058436
HBB	-0.058106
CNN3	0.057667
VAMP2	0.057652
MOBP	-0.056657
ITM2C	0.056591
EGR1	0.056297
ADM	0.055822
REEP5	0.055797
SLC6A3	-0.055564
HSPB1	0.055204
SYT11	-0.055049
TMEM59	-0.054840
EIF4A2	-0.054343
GPR37	-0.054282
EVL	-0.053671
H3F3B	0.052921
CHURC1	-0.052362
CTSB	0.052351
OAZ1	-0.051801
APOC1	0.051408
UBB	-0.051345
SPARC	-0.051312
PEG3	-0.050973
RPS19	0.050606
MSH3	-0.049621
PEA15	0.049026
CNDP2	-0.048994
CDAN1	0.048908
PPA1	-0.048300
HIST1H4C	0.048133
PNPT1	0.047995
SPOCK2	-0.047853
PCMT1	0.047614
FAU	-0.045609
FSCN1	-0.045078
TMBIM4	0.045023
GNB2L1	0.044917
ARHGDIB	0.044647
MDH2	-0.044339
GMFB	-0.044273
CAMK2N1	-0.044012
MAT2A	0.043876
ITM2A	-0.043816
BRSK1	-0.043684
SYT4	0.043592
DAZAP2	0.043385
SCG2	-0.043337
CCND1	0.043027
RPS28	0.042751
GNAS	-0.042613
RPS27A	-0.042538
RPS16	0.042217
TUBA1C	0.042140
HSP90AB1	0.041983
MAG	-0.041802
OLR1	0.041704
EPDR1	-0.041549
RPL31	-0.041502
CIRBP	0.041339
TOMM7	0.041169
MTCH1	0.041068
PPP1R14A	-0.040956
PDE4C	0.040766
XPNPEP3	-0.040727
ERAP2	-0.040666
MAGT1	0.040662
SEPW1	-0.040652
C2orf82	0.040375
RPS29	0.040334
CKB	-0.040318
IL18	0.039947
CALY	-0.039925
DUSP1	-0.039832
ENO1	0.039529
RPL27	0.039252
NEFM	-0.039065
ATP5A1	-0.039059
DNAJB1	0.038921
RPS12	0.038725
TNS3	-0.038532
CD14	0.038381
CLIP3	-0.038273
AMY1C	0.038181
ACTG1	0.037705
SOD1	0.037632
BEX2	0.037445
TUBB4A	-0.037431
CXXC5	0.037283
MOG	-0.037282
SLC25A5	-0.037131
ZCCHC24	-0.036954
AIRE	0.036868
YWHAH	-0.036862
EIF4A1	0.036835
MAP6D1	0.036784
COX8A	-0.036690
RPS23	-0.036606
GATS	-0.036570
RPL18A	0.036456
GSTT1	-0.036194
CLUAP1	-0.035939
RPL10A	0.035873
RNASE1	-0.035836
NDUFA3	-0.035376
PAQR8	-0.035198
KLF2	-0.035019
MT1F	0.035005
CSF1R	0.034638
TUBA1A	0.034498
CSRNP1	0.034257
AKR1D1	0.034118
SLC17A6	-0.033996
CARNS1	-0.033872
CDC42EP4	0.033849
TMEM59L	-0.033773
TACC1	-0.033698
PRR13	0.033690
RPS13	0.033343
A2M	0.033261
INA	-0.033261
TIMM10	-0.033197
RPLP1	0.033184
RBM22	0.033174
ARHGEF6	0.033093
RPL18	0.032897
ZMAT3	-0.032884
SLIRP	-0.032587
SLC1A3	0.032580
SEPT4	-0.032520
HBA2	-0.032499
ABCA1	0.032380
ALPP	0.032176
GABPB2	0.032121
RPS3A	0.032103
RPS26	0.031956
CCL3L3	0.031906
BCL6	0.031794
GLDN	0.031785
CERS6	0.031767
KIF1A	-0.031751
FAM107B	-0.031724
TRIM2	0.031695
DCAKD	0.031564
MX1	0.031351
TUBB3	-0.031210
TCFL5	-0.031034
BHLHE40	0.030990
DNER	0.030828
HLA-DMB	0.030811
HAVCR2	0.030740
SEMA4D	0.030603
RPLP2	0.030572
GSTP1	0.030565
OMG	-0.030540
NRSN1	-0.030453
LLGL1	0.030428
PPP1R3C	0.030395
ACTB	0.030353
PRCP	0.030344
BCYRN1	0.030232
GLTP	0.030184
LIPA	0.030127
TBCB	-0.030094
MAP1A	-0.030059
SNAP25	-0.030030
HDDC2	-0.029908
CD74	0.029900
HMGCS1	0.029879
RPL19	0.029873
CPLX1	-0.029812
NLRP8	0.029522
ORC6	0.029399
RAB3C	-0.029391
TF	0.029136
RRAGA	-0.029097
LIMCH1	0.029026
NDUFV1	-0.028791
GSTM3	0.028785
RPL37A	0.028781
RPL36AL	0.028768
SH3GLB2	-0.028572
COX5A	-0.028564
EZR	0.028527
CEP19	-0.028466
DYNC1I1	0.028447
NDUFA11	-0.028399
RPS17	0.028313
MAL	-0.028257
CD99L2	-0.028239
RPL5	0.028095
SAT1	0.027954
RPSA	0.027928
KLC1	-0.027750
C12orf10	-0.027712
SCARB2	0.027688
ANAPC13	-0.027671
CEBPB	0.027621
RPS10	-0.027482
REEP1	0.027336
PPP1R15A	0.027243
MYL6B	-0.027196
NDRG4	-0.027169
NKX6-2	-0.027062
RGMA	0.027054
AMER2	-0.026963
TECR	-0.026887
C1orf61	-0.026852
DENND5A	-0.026781
STK39	-0.026633
LAMTOR1	-0.026534
MYL6	-0.026474
MDH1	-0.026395
RPL3	-0.026272
SUMF2	0.026266
TUBB2B	0.026145
RNF181	0.026119
ATP6V1A	0.025845
RPL9	0.025796
TUBB2A	-0.025795
GUSBP2	-0.025729
KCNJ6	-0.025707
HTRA1	-0.025633
PSMB1	0.025623
RPS5	-0.025611
NDUFV2	-0.025513
NDUFA8	-0.025315
DPYSL3	0.025127
PTPN11	-0.025120
SLC2A1	-0.025118
DAPP1	0.025072
MARCKS	0.024997
CST3	-0.024982
NSA2	0.024886
USP49	0.024851
SPCS1	-0.024843
UQCRFS1	-0.024832
FARSB	0.024790
DNAJA4	0.024764
PSMB7	-0.024704
CCL2	0.024652
TH	-0.024621
CNTNAP4	0.024586
EIF3E	-0.024528
NDUFA4	-0.024520
PHGDH	0.024501
CYC1	-0.024474
PLEKHB1	0.024459
PLEKHH1	0.024304
THBS2	0.024255
PLLP	-0.024226
RPS6	-0.024125
FKTN	0.024113
MIF	-0.024105
ALDH9A1	0.024059
SLC44A4	0.024049
PPA2	0.024039
BSCL2	-0.024024
ATP6V1E1	0.024013
PACSIN1	-0.023988
C1orf54	0.023951
AHR	0.023923
NDUFS3	-0.023872
RPL11	0.023774
EIF4B	0.023767
TMEM47	0.023718
TMEM9B	0.023689
NPTN	-0.023540
PCBP2	0.023437
DAAM2	-0.023354
SLC6A1	-0.023284
BEND6	-0.023259
BCL2L2	-0.023232
COX4I1	0.023165
EPB41L3	-0.023158
CRYBB2	-0.023142
SLC1A2	-0.023125
TSC22D4	-0.023100
SRSF5	0.023047
IFI6	0.022925
TMSB4X	0.022897
HSD17B7	0.022843
RHOQ	-0.022746
ALOX5AP	0.022734
RPL41	0.022712
JTB	-0.022678
CNDP1	-0.022584
LAMP2	-0.022547
SLC44A1	-0.022436
STMN4	0.022398
C15orf59	-0.022346
CADM1	0.022336
COX6C	-0.022318
SH3GL2	-0.022295
RPL12	0.022285
HLA-DMA	0.022237
CBX6	-0.022230
DDX5	0.022192
SRRM2	0.021975
OCIAD1	0.021963
HLA-A	0.021954
CAPN3	-0.021943
COPS5	-0.021902
ZFYVE20	0.021840
TRIM44	-0.021825
UCHL1	0.021812
RTN3	-0.021761
FTL	-0.021735
B2M	0.021732
NDRG1	-0.021695
ATP6AP1	0.021624
ECH1	-0.021511
TP53INP2	-0.021465
UQCRBP1	0.021417
CCNI	-0.021403
DDIT4	0.021401
UBC	-0.021400
GABBR2	-0.021368
NUDC	-0.021295
SNCA	0.021233
ENHO	-0.021230
ID2	0.021085
RPL13AP3	0.021004
SQSTM1	0.020931
APLNR	0.020926
RPS15A	0.020909
H3F3A	-0.020906
MAP1LC3A	-0.020901
HSP90B1	-0.020896
DACT3	0.020881
TNFRSF21	0.020775
SPTAN1	-0.020740
ACTR2	-0.020716
THBS4	-0.020667
SRSF2	0.020635
FAM168A	-0.020620
WFS1	0.020434
BSG	-0.020324
TUBB4B	-0.020272
PRDX6	0.020268
ETNPPL	-0.020257
LILRB3	0.020236
FCGBP	0.020188
MAP1LC3B	-0.020177
COX6B1	0.020158
C5orf28	0.020083
PDXK	-0.020051
GJC1	0.020002
ADIPOR2	-0.019998
GLUD1	-0.019978
TCEAL2	0.019955
LAPTM5	0.019946
GDI2	0.019929
TNPO2	-0.019884
HSD17B4	0.019871
NCAN	0.019857
ADD1	-0.019784
MRPL23	-0.019755
CNTN2	0.019744
HIST2H2AA3	0.019725
CCDC136	-0.019709
LDLR	0.019708
CCZ1B	-0.019697
HLA-DPA1	0.019674
ARL6IP1	0.019664
MT2A	-0.019658
RPA2	0.019596
PGRMC2	0.019584
EGLN2	-0.019547
TMEM160	-0.019496
PMP2	-0.019421
BIN1	0.019334
GPR137	-0.019272
HES4	0.019243
TAF15	0.019235
RPS14	-0.019229
EFHD1	-0.019226
GLS	-0.019205
AKR7A2	0.019203
CAP2	-0.019165
GPX3	0.019083
QDPR	0.019081
CETN2	-0.019046
RPL39	-0.018991
DNAJC28	0.018958
PFN1	0.018908
C16orf92	-0.018857
ALKBH5	0.018686
TUG1	0.018646
ARHGAP44	-0.018643
CD44	0.018622
WBP2	-0.018615
NINJ2	-0.018606
ATP9A	0.018597
PTGES3	0.018586
BLZF1	0.018500
SLC48A1	-0.018456
PGRMC1	0.018453
PRNP	-0.018392
OPALIN	-0.018392
UNC13C	-0.018371
SPON1	0.018353
PARK7	0.018347
GPD1L	-0.018286
FABP7	0.018274
UQCRC1	-0.018247
TMEM256	-0.018227
MAP4	0.018218
CSTB	-0.018149
EIF4H	-0.018062
SSU72	0.018033
ATP6V0B	-0.018029
MT1M	-0.018021
CERCAM	-0.017998
SPARCL1	-0.017992
MSRB2	0.017947
DMC1	0.017925
CEBPD	0.017823
GNG3	0.017822
NCOA4	0.017777
NDUFB2	-0.017747
MARCKSL1	-0.017743
FEZ1	-0.017733
RPL35A	-0.017731
GDI1	-0.017703
C1orf122	-0.017673
ATP5O	-0.017673
CLPTM1	-0.017528
STXBP6	-0.017499
PLP1	-0.017457
GLTSCR2	0.017457
GADD45B	0.017457
GNG7	-0.017451
ARNT2	-0.017430
ANKRD46	-0.017352
CH25H	0.017351
C1QC	0.017342
PCNP	-0.017324
NDUFA12	-0.017310
LILRB1	0.017261
IMP4	-0.017248
COL4A5	-0.017243
ATP5B	-0.017118
DBNDD2	0.017019