!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	NVP-TNKS656 (tankyrase inhibitor)
!smiles	COC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC(=O)C5=C(N4)CCOC5
!pubchem_cid	71227201
!cell_type	SW480 cancer cells
!organism	human
!end_metadata
MT2A	0.196322
MT1E	0.160672
KRTAP2-3	0.157234
MT1F	0.144528
MT1X	0.143910
AKAP12	0.137325
MT1H	0.123440
MALL	0.122405
DUSP5	0.114866
SDC4	0.109505
ERRFI1	0.103319
IER3	0.093777
MT1HL1	0.089463
SERPINE1	0.088045
ETS1	0.080957
FOSL1	0.079274
S100A2	0.076004
STARD4	0.075539
SLC38A2	-0.074239
ICAM1	0.071797
ID2	-0.071062
MAP2K3	0.070633
MSX1	-0.070273
FHL2	0.070033
GPRC5A	0.069794
SFN	0.069235
KLF10	0.065059
CD83	0.063694
PLAUR	0.062820
EPHA2	0.062534
SLC16A6	0.062351
BIRC3	0.062199
BAMBI	-0.061339
S100A16	0.060030
MYADM	0.059729
PFKFB3	0.059675
BIRC2	0.059010
SLC20A1	0.058716
EGR3	0.057343
PHLDA1	0.056684
F3	0.056224
WBP1L	-0.055356
SLC30A1	0.054750
TNFAIP2	0.054693
RPL9	0.054284
KLF6	0.053115
ANXA2P2	0.052477
PMEPA1	0.052331
MAFF	0.052038
IER2	0.051617
DDIT4	-0.051294
IFRD1	0.050827
SMURF2	0.050518
DDX21	0.050090
SOX9	0.049405
DNTTIP1	0.049359
PIM3	0.049267
TRIM16	0.048612
LINC01119	0.048060
RPL21	0.047893
NET1	0.047582
SH2B3	0.045843
KLHL21	0.045774
PPIF	0.045400
SLC25A32	0.045103
WWTR1	0.044989
CD3EAP	0.044794
KIAA0355	-0.044622
PIM1	-0.044525
DDX5	0.044456
AMD1	0.044345
RPL41	0.044245
JAG1	0.043543
AP3S1	0.043495
EMP1	0.043450
MAT2A	0.043187
EGR1	0.043174
TNFRSF21	0.042920
CDKN1B	-0.042864
GCH1	0.042856
TINAGL1	0.042524
ACTG1	0.042322
HSPA8	0.042059
IFNGR2	0.041891
RPL26	0.041732
ZNF697	0.041203
CDCA7L	-0.040683
CNN2	0.040550
APCDD1	-0.040316
LIF	0.040126
CCRN4L	0.039938
GADD45A	0.039914
PDGFA	0.039811
PMAIP1	0.039795
TUBB2A	0.039771
NFKBIA	0.039759
RPL34	0.039658
SMIM15	0.039083
GOLPH3L	-0.038957
VCL	0.038941
ASAP2	0.038759
ND2	0.038686
UBE2C	0.038440
NIP7	0.038123
MT1G	0.038119
SLC35F2	0.037683
RBM12	0.037592
SLC7A7	-0.037031
FAM134A	-0.036830
C3orf52	0.036735
PTP4A1	0.036697
WDR43	0.036636
RPL39	0.035791
ZNF468	0.035400
AFAP1L2	0.035099
CYR61	0.035069
NOP58	0.034839
HPCAL1	0.034785
RPL7L1	0.034758
DNMBP	0.034560
TXNRD1	0.034324
SNHG15	0.034190
CORO1C	0.034179
NDC80	-0.034145
GPX8	-0.034106
TUBA1C	0.034004
ORAI3	-0.033933
RMI2	-0.033921
ETF1	0.033571
CAPNS1	0.033360
HIF1A	0.032923
GNL3	0.032899
DKK1	0.032844
SLC39A10	-0.032719
ERVMER34-1	-0.032555
JUN	0.032408
SERINC5	-0.032393
TNFRSF12A	0.032259
NFATC2	0.032115
RPS25	0.031891
MALAT1	0.031754
SACS	0.031548
TMEM139	-0.031528
ARHGEF18	-0.031468
TXN	0.031457
NSUN2	0.031233
EREG	0.031167
BZW2	0.031131
CDCA4	0.031087
CSF2	0.031075
HOXA1	-0.030998
TNS4	0.030883
CHSY1	0.030809
CTR9	-0.030793
FAM102B	-0.030536
TUBB	0.030481
KRT23	0.030258
NME7	0.030201
ITGA2	0.030169
C16orf54	-0.030131
FJX1	0.029852
KRT19	0.029686
DCLK1	0.029614
RRM2B	-0.029514
RRS1	0.029486
ZMPSTE24	0.029345
RPL24	0.029225
ACTB	0.029223
DUSP6	0.029188
SRSF2	0.029155
ZYX	0.029133
ARMCX6	-0.029082
SNX9	0.029072
NAA50	0.029065
ODC1	0.029023
FOXM1	-0.028985
RPS11	0.028947
PDLIM4	0.028945
NEIL3	-0.028796
SCML1	0.028641
WNT5A	0.028438
FUT4	0.028420
EPHA4	0.028409
RCC2	0.028365
ERH	0.028364
KIF20A	-0.028353
FAM217B	-0.028145
FAT1	0.028076
NMD3	0.028035
RPL23A	0.028023
ATP1B1	0.027980
KCTD11	0.027871
FOXQ1	-0.027863
TM4SF1	0.027792
TIFA	0.027484
YWHAZ	0.027384
SOWAHC	0.027332
EIF3J	0.027275
RPL27	0.027265
CNBP	0.027176
TUBB4B	0.027142
YWHAG	0.027086
RARS	0.027013
MAK16	0.026993
ZFP36L1	0.026924
LOC100507507	0.026873
AEN	0.026804
EIF6	0.026713
RPL11	0.026691
TNFRSF10A	0.026582
OXR1	-0.026577
ARGLU1	0.026559
RPL36	0.026482
SNHG1	0.026465
LOC100130468	-0.026445
SKIDA1	-0.026359
MCL1	0.026313
GLI3	-0.026245
RPS20	0.026243
H3F3B	0.026226
TUBB6	0.026215
ZNF280C	0.026128
CXCL8	0.026098
CDC7	-0.026045
TUBB2B	0.026041
SLC35G2	0.026029
RTN4	0.025976
NAA20	0.025964
SH3PXD2A-AS1	0.025942
RASL11B	-0.025880
SRSF6	0.025776
MIR21	0.025768
FAM169A	-0.025739
PITPNB	0.025713
LOC284023	0.025653
DPYSL2	0.025556
NUDT19	0.025552
LENG8	0.025506
BMP4	-0.025489
RPS18	0.025458
BAZ1A	0.025441
GJB2	0.025438
PHLDA2	0.025431
EIF2S1	0.025396
COX2	0.025366
FZD7	-0.025363
TOMM20	0.025221
DCBLD2	0.025185
ABHD6	-0.025169
KPNA4	0.025141
DKC1	0.025108
RAP2B	0.025021
PTDSS1	0.024952
CHCHD3	0.024932
RPL35	0.024655
RPS26	0.024508
PLAU	0.024407
EDAR	-0.024384
CDV3	0.024223
KRT18	0.024216
EIF4H	0.024191
HNRNPA1	0.024180
SLC12A2	0.024128
COTL1	0.024063
C6orf62	0.024055
CYP24A1	0.024043
WDR3	0.024002
ARF6	0.023910
BZW1	0.023900
HOTAIR	-0.023892
FAM107B	0.023858
AXL	0.023794
ELL2	0.023739
ANXA2	0.023696
BMP7	-0.023593
TIMM9	0.023589
ATG12	0.023476
HSP90AB1	0.023434
PPTC7	0.023408
RBM20	-0.023377
ADORA2B	0.023341
HMGB1	0.023340
NDRG1	0.023314
MSANTD3	0.023265
AURKA	-0.023257
PTMA	0.023164
MMGT1	0.023122
UXS1	0.023008
MRFAP1	0.022958
MYL12B	0.022927
B3GNT5	0.022913
MTMR4	-0.022900
PLD6	0.022855
RPL32	0.022834
OXTR	0.022725
TOP1	0.022587
EHHADH	-0.022559
TGFB1I1	0.022524
TSPAN13	0.022492
SMARCD2	-0.022460
PLP2	0.022433
CTPS1	0.022388
FABP5	0.022341
PRDM1	0.022339
WNT9A	0.022325
EIF5A2	0.022281
PTP4A2	0.022275
ARF4	0.022254
RNF19A	0.022169
HMMR	-0.022152
CDC42EP3	-0.022124
ZC3H12C	0.022107
SLC9A6	-0.022083
GOLPH3	0.022050
SERPINB9	0.022048
NCAPD2	-0.022041
SGK223	-0.021987
HOXB2	0.021895
ABCE1	0.021887
HSD17B11	-0.021817
C2CD5	-0.021760
ENC1	0.021712
CS	0.021707
RAPH1	0.021690
TTK	-0.021644
SLMO2	0.021631
METTL7B	0.021564
NOG	0.021544
PPP1R15B	0.021543
HNRNPDL	0.021541
DNTTIP2	0.021518
SP5	-0.021486
NRAS	0.021479
SPRY4	0.021476
ITGA6	0.021475
DSN1	-0.021404
BRD9	0.021218
IRS2	-0.021215
LOC158960	-0.021197
TNIP1	0.021193
RNF149	0.021181
UAP1	0.021173
C19orf33	0.021105
TXNIP	-0.021102
KCNJ5	-0.021097
DEPDC1B	-0.021075
SMAGP	0.020951
USP12	0.020911
TMSB10	0.020902
CTDSP2	-0.020846
NPM1	0.020756
HOXA7	-0.020737
PSAT1	-0.020733
EIF1AX	0.020724
OTUD1	-0.020667
APOBEC3B	0.020642
RPL4	0.020618
CDKN1A	0.020594
NIFK	0.020574
DHRS3	-0.020567
MAPRE1	0.020542
PAX8-AS1	0.020532
ARHGAP29	0.020523
C6orf203	-0.020512
RPL19	0.020490
CLIC1	0.020485
MYH9	0.020423
ZWINT	0.020391
BUB1B	-0.020379
AARS	-0.020305
BAG5	0.020288
OARD1	-0.020220
LRRC8A	0.020218
SGMS2	0.020194
CXCL16	0.020185
EIF1	0.020147
NAMPT	0.020132
FBXO33	-0.020118
ZC3HAV1L	0.020117
MIR22HG	0.020116
MYC	0.020020
FEM1A	0.019964
TNFRSF1B	0.019964
LAMC2	0.019898
PRNP	0.019886
ZNF322	-0.019868
ATP2B4	0.019853
MARS2	0.019793
HSP90AA1	0.019793
IMPA1	0.019609
BTBD10	0.019608
RPS29	0.019605
SERPINB1	0.019595
ULBP2	0.019593
FNBP1L	0.019584
KIZ	-0.019571
UHRF2	-0.019485
INSIG2	0.019448
CCT2	0.019420
NPC2	0.019419
RABGAP1	-0.019398
TPX2	-0.019396
RPL36A	0.019378
TMA16	0.019375
QARS	-0.019363
STK24	0.019348
CENPA	-0.019339
PDP1	0.019220
ND6	0.019215
TPM4	0.019194
PIK3C2B	-0.019142
S100A11	0.019122
CSRP1	0.019098
HNRNPH1	0.019090
PIP4K2C	0.019083
MAFK	0.019069
RRP1B	0.019051
ARPC2	0.019038
GAPDH	0.019021
PPIA	0.019012
PTTG1IP	0.019005
MAPK6	0.018976
SHROOM3	-0.018940
CTDSPL	-0.018933
SPAG1	0.018926
BCAR3	0.018896
IL23A	0.018894
CRIM1	0.018889
FAM220A	-0.018873
WSB2	0.018858
CASC10	-0.018848
NUAK1	-0.018844
WDR75	0.018835
RPS10	0.018766
ZBTB2	0.018764
STAU1	0.018743
GNPNAT1	0.018716
CDCP1	0.018701
EZR	0.018693
PARD6B	0.018693
POLR3F	0.018682
ZBTB38	0.018670
GAR1	0.018667
TRIM47	0.018665
CPSF3	-0.018663
INSIG1	-0.018607
ZNHIT6	0.018587
WFDC3	0.018496
RAD23B	0.018467
NDEL1	0.018461
AZIN1	0.018459
LDHA	0.018398
C4orf32	0.018389
PLK2	0.018378
PURB	0.018354
RPL37A	0.018343
CCND1	0.018322
LIMS1	0.018284
DPM1	0.018278
FAM136A	0.018276
UBA52	0.018247
KDM6B	0.018210
MTPN	0.018204
AHR	0.018201
CDCA3	-0.018197
MAOA	0.018180
BRIX1	0.018164
TMEM45B	-0.018101
RBBP7	-0.018020
BRI3	-0.017995
DENND5A	0.017942
EHD1	0.017938
NDUFAF4	0.017913
DDX18	0.017909
SERTAD2	0.017904
HIST1H2BK	0.017864
YWHAE	0.017835
EIF3A	0.017788
RNF220	-0.017778
NUPL1	0.017758
SDCBP	0.017742
USP43	0.017736
TACSTD2	0.017698
SRSF7	0.017698
TMEM41B	0.017675
UGDH	0.017669
MYL6	0.017664
MFSD6	0.017648
LINC00973	0.017646
NR1D2	-0.017646
SOCS2	0.017645
DYNLT3	0.017604
PKM	0.017600
PSMD12	0.017599
PLEK2	0.017598
SMS	0.017579
SGK1	0.017578
PANK1	-0.017528
GTF2F2	0.017510
PDE4D	-0.017508