!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estrogen
!ligand_id	CHEBI:50114
!cell_type	human epithelial ovarian cancer (EOC) cells
!organism	human
!end_metadata
CSTA	-0.074742
PROL1	-0.070642
FOXQ1	-0.062827
CTTNBP2	-0.057206
EDIL3	0.055959
PCOLCE2	0.054839
AMIGO2	0.054686
DEFB1	-0.054448
SLC4A11	-0.054011
KCND2	0.050621
PGR	0.049659
TMPRSS4	-0.047842
HLA-DPB2	0.047672
VGLL3	0.047500
LUM	0.047406
STEAP1	0.045309
PDGFC	0.042837
DDIT4L	-0.042395
PCP4	-0.042291
PSCA	-0.042130
BLNK	-0.041726
CYR61	0.041570
GLCE	-0.041424
OLFML3	0.041172
KRT13	-0.041135
B3GNT3	-0.041064
FMOD	0.041015
COL3A1	0.040883
CRISPLD1	0.040380
ROPN1B	-0.040094
SPATA2L	-0.039552
WLS	0.039244
TMEM132E	-0.039065
EYA1	0.038859
CLDN11	0.038806
PP14571	-0.038740
MAL	-0.038657
GDPD5	-0.038647
ROPN1	-0.038643
FAM89A	0.038037
SLC6A12	-0.037742
SSTR1	0.037143
BMP7	-0.036685
KRT81	0.036664
DSC1	-0.036574
SCGB2A1	-0.036550
COL24A1	0.036321
BORA	0.036160
LCN2	-0.036122
TMPRSS11E	-0.036098
CTGF	0.035975
SMIM5	-0.035783
SLC12A1	-0.035778
XDH	-0.035754
KLK7	-0.035681
TMEM61	-0.035634
FBXL7	0.035412
GABRE	0.035375
LRCH2	0.035180
SCD	0.034801
MUC16	-0.034796
SULF2	0.034758
MAMLD1	-0.034752
EFEMP1	-0.034585
CCNA1	-0.034256
ADAMTS3	0.034254
CPA5	0.034012
DNM1P35	-0.034003
ALS2CL	-0.033979
TSPAN1	-0.033521
FAH	-0.033390
SH3PXD2A-AS1	-0.033282
RAPGEF3	-0.033153
IRX3	0.033118
CAV1	0.033026
CYTL1	0.033006
NOX4	0.032983
DHRS2	-0.032953
RNF152	0.032843
UCA1	-0.032588
PRELP	0.032298
GLDC	-0.032127
CCDC81	-0.032115
LOC100130476	-0.032107
THY1	0.032032
CSPG4	-0.031821
BMP5	0.031491
CDR1	0.031469
LINC01314	-0.031458
GREB1	0.031429
GPR64	-0.031400
THBS1	0.031291
TMEM45A	0.031230
ZNF404	-0.031220
GLT8D2	0.031176
KRT15	-0.031044
BDKRB2	-0.030982
KLHL2	-0.030693
C2orf50	0.030665
TRIB2	0.030505
SLPI	-0.030257
FXYD3	-0.030257
TMPRSS11B	-0.030240
GPR110	-0.030208
MYOM1	-0.030206
SCEL	-0.030173
MRPL1	0.030137
CDC7	0.030098
AXL	0.029896
IFIT1	0.029826
SLC16A9	0.029759
BHLHE41	-0.029620
PPL	-0.029570
SPRYD4	-0.029433
CASP7	-0.029423
C10orf55	-0.029406
COL6A3	0.029403
CTHRC1	0.029364
SACS	0.029320
LINC01116	0.029314
CAMK2N1	-0.029207
KRT4	-0.029200
RNF182	0.029182
TENM2	0.029077
LINC00839	0.029040
KLRG2	-0.029031
FSCN1	0.028977
C10orf99	-0.028968
ATL1	0.028935
ST6GALNAC5	-0.028916
RPRML	0.028756
ZNF195	0.028623
ST6GALNAC2	-0.028581
LTBP1	0.028334
GCNT4	-0.028275
RSPO1	0.028247
PROS1	0.028074
SLC7A7	0.027973
GPR125	0.027790
RASGRP1	0.027727
SHCBP1	0.027716
GNG11	0.027675
ARHGAP19	0.027620
CD24	-0.027581
CPA4	-0.027548
PRTFDC1	0.027528
PROM1	0.027454
LDLRAD4-AS1	0.027426
WT1-AS	0.027297
CASQ2	0.027200
RHOBTB1	0.027027
IL32	0.027010
C11orf45	-0.026969
CTSC	0.026917
FKBP1B	0.026901
HIST2H2BE	-0.026851
TBC1D2	-0.026813
OSTM1	0.026811
ACN9	0.026796
C1orf186	-0.026744
DAPL1	-0.026740
DEFB124	-0.026647
ADORA2B	-0.026459
C17orf96	0.026340
SYN3	-0.026312
SPRR3	-0.026159
PALM3	-0.026071
SGK3	-0.026029
LOC100506718	0.026007
EID3	0.025980
CPE	0.025959
EID2B	-0.025946
PMAIP1	0.025941
TET1	0.025934
C8orf31	-0.025896
XRCC4	0.025888
ANXA6	0.025816
AS3MT	0.025810
GCNT3	-0.025800
CYP4F3	-0.025774
LOXL1-AS1	0.025672
ITGB5	0.025582
LRRN1	0.025562
LOC100131581	-0.025402
BNC1	0.025379
C2orf40	-0.025348
AADAC	0.025329
PPAP2B	-0.025324
PLA2G7	-0.025302
C1orf198	0.025271
ALDH3B2	-0.025207
PPP1R3C	-0.025203
GPN2	0.025184
PIN1	0.025111
DPY19L2	0.025107
ST3GAL5	-0.025059
LOC283278	-0.025054
CENPW	0.025022
KCNRG	-0.024979
LYPD3	-0.024955
HAUS7	-0.024955
DPP10-AS1	0.024917
DHRS1	-0.024915
LRRC36	-0.024913
RBP4	-0.024830
PRKX	0.024795
ERRFI1	0.024763
TRIL	0.024737
PLXNA4	-0.024699
CTNNAL1	0.024696
MFAP5	0.024680
ZNF704	-0.024664
SLC34A2	-0.024553
GNAI1	0.024545
FAM169A	-0.024539
SCG5	0.024494
PKIB	0.024430
KIAA1644	-0.024428
DHCR24	-0.024418
RASSF9	0.024412
LIN28B	0.024360
SPHK1	-0.024356
FUT8	0.024353
SPINK2	-0.024313
CENPE	0.024310
MXRA5	0.024264
PYGL	0.024221
ZNF112	0.024219
ZNHIT3	0.024207
PRKXP1	-0.024122
KCNJ2	0.024111
AQP3	-0.024091
SORL1	-0.024070
RBBP8	0.024056
PRSS8	-0.024043
HJURP	0.024012
MTX1	-0.023937
MGC16275	0.023927
HTRA1	-0.023918
FAM213B	0.023887
MUCL1	0.023840
FOXD1	0.023815
NAT6	-0.023803
SCGB1D1	-0.023698
SLC28A3	-0.023639
BAG2	0.023611
KIF18A	0.023602
PHLDA2	-0.023533
ZNF285	0.023522
PLAC8L1	0.023461
PEG10	0.023456
BZRAP1	0.023442
FYN	-0.023441
DDC	-0.023427
ZNF485	0.023356
PIPOX	-0.023352
FZD7	0.023350
FAM171A1	0.023327
MARCKS	0.023316
GGT6	-0.023278
MFAP4	0.023263
LOC100507391	-0.023246
TESK1	-0.023215
LY6D	-0.023185
KCNJ4	-0.023180
C19orf66	-0.023137
SMR3B	-0.023084
ZNF185	-0.023018
RAP1GAP2	-0.022945
ZSCAN26	0.022936
THSD7B	0.022912
PRSS33	-0.022861
SLC16A1	0.022795
ZNF711	0.022784
TAF4B	0.022751
KLK11	-0.022719
ANXA3	0.022656
SDR42E1	0.022655
PGBD1	0.022651
MAFB	-0.022646
HAUS1	0.022612
FAM43A	-0.022553
RHBDL2	-0.022548
ZXDA	0.022509
PRG2	0.022506
SLC39A2	-0.022504
SCAMP1-AS1	-0.022487
KANSL1-AS1	-0.022470
CADM3-AS1	0.022467
PLEKHS1	-0.022446
CFI	0.022441
CALHM1	-0.022427
ZNF204P	-0.022345
CPNE8	0.022311
OAS1	0.022297
ZNF134	0.022297
IRS1	0.022270
FAT3	0.022222
BMP4	-0.022210
NDC80	0.022205
SLC25A20	-0.022185
SLC16A4	0.022175
NCF2	0.022172
LOC100505650	-0.022170
EPHB6	-0.022097
NEXN	0.022081
CCNB1	0.022056
HCG22	-0.021986
ASUN	0.021986
PIK3C2B	-0.021978
KDELR3	-0.021974
KIT	0.021960
ZHX2	-0.021857
RYR3	-0.021802
FGF9	0.021785
KLK6	-0.021769
TIMP3	0.021750
BSND	-0.021729
STX18-AS1	0.021688
EMC6	0.021654
ZNF367	0.021625
LINC01106	0.021624
TMEM133	0.021592
PSMG1	0.021545
VEGFC	-0.021510
SFTA1P	-0.021503
PBK	0.021493
SLC27A6	0.021490
EVPL	-0.021478
MAMDC2-AS1	-0.021413
SCARA3	-0.021413
TP63	-0.021393
HBE1	-0.021374
GPR160	-0.021359
TMEM100	-0.021353
ENC1	0.021352
PMS2P4	-0.021315
TGFB1I1	0.021297
CLIP4	0.021275
PPP2R2B	0.021271
SLC44A4	-0.021267
CYP24A1	0.021255
ZNF8	0.021246
AMT	-0.021224
VCAM1	0.021215
FAM26F	0.021181
SLMO1	0.021137
PROCR	0.021130
ATG4A	-0.021117
COCH	0.021098
GULP1	0.021060
ME2	0.021053
TMEM169	-0.021041
ZNF184	0.021037
GLIS3	0.020982
CHST3	0.020978
SLC25A29	-0.020971
SERPINE2	0.020962
SVOPL	-0.020948
ALMS1-IT1	0.020882
TRIM29	-0.020862
NEK2	0.020854
COL4A6	0.020838
SLC6A15	0.020832
FBXO32	-0.020805
XAGE2	0.020789
NDUFV2-AS1	-0.020787
C1orf53	-0.020781
WFDC12	-0.020763
DEPDC1	0.020743
COL5A2	0.020707
SETMAR	0.020691
PLEKHA7	-0.020676
OLFML2A	-0.020645
METAP1	0.020628
A1BG	-0.020613
PAX8-AS1	-0.020610
LRRTM1	-0.020591
TRIM16	-0.020587
FGFR3	-0.020545
SPTSSB	-0.020518
RPL22L1	0.020471
LACTB	0.020408
NPY4R	-0.020395
MAK16	0.020385
CXCL1	-0.020382
ZWILCH	0.020355
GJA1	0.020352
INSIG2	-0.020344
LOC101929717	-0.020337
ESAM	-0.020323
LOC100506098	-0.020319
SRCIN1	-0.020302
MALL	-0.020279
PHKA1	0.020267
EPB41L4A-AS1	0.020262
RILPL2	0.020247
RHOU	-0.020231
LAGE3	-0.020209
OSBPL11	-0.020205
MIR99AHG	0.020193
SLC16A1-AS1	0.020113
CMTR2	0.020112
IKZF2	-0.020111
LOC339568	-0.020109
DPY19L2P2	0.020103
TNFRSF21	0.020086
IGSF11	-0.020018
ZNF861P	-0.020000
KIF18B	0.019993
KLK10	-0.019976
PWAR5	0.019964
GJC1	0.019964
MYBL1	0.019961
IFI44L	0.019946
PLSCR4	0.019938
PGAP3	-0.019927
LOC730101	0.019885
SLC43A3	0.019882
LOC153682	-0.019877
LRRC8C	0.019873
LOC102606465	0.019851
MBOAT1	0.019845
NTN4	-0.019835
LIX1L	0.019833
CADM3	0.019800
KNTC1	0.019782
SMPDL3A	0.019745
ATP6V1E2	0.019706
ELOVL6	0.019638
BIN1	-0.019638
SKA1	0.019613
TCF4	0.019609
CMPK2	0.019606
FOXO6	-0.019587
GRB14	0.019541
CASC1	0.019540
ZNF236	0.019538
APOL3	-0.019509
HIST1H3F	0.019508
MACC1	-0.019499
FAM198A	0.019490
SAMD12	-0.019489
VWA8	0.019472
CPVL	0.019465
LRRTM2	-0.019455
NUDT15	-0.019431
LOX	0.019428
SBSPON	0.019418
MPDZ	0.019400
MICALCL	-0.019366
CDK6	0.019360
TLCD1	0.019348
DGKA	-0.019345
TTC9	-0.019334
PLEKHF2	-0.019332
CXCL17	-0.019274
GCLM	0.019263
WDHD1	0.019254
SLC35B3	-0.019237
AKR1C3	0.019204
EVA1C	-0.019189
IFT74	0.019187
ACAD8	0.019167
TMEM79	-0.019165
ZNF813	0.019148
ZNRF2P1	0.019143
C8orf88	0.019105
SNX10	0.019100
PRSS23	0.019081
HEG1	0.019078
CABLES1	0.019050
FGD1	-0.019038
LINC00284	0.019019
STARD9	0.019019
TXN	0.019018
C15orf48	0.018970
LOC338667	-0.018963
ZNF565	0.018959
LOC441454	-0.018956
ROBO3	0.018953
TTC7B	0.018946
SYTL2	-0.018931
ZNF267	0.018927
GPX7	0.018918
LCN12	-0.018909
CARD16	0.018902
DEPTOR	0.018900
FLJ32255	-0.018896
PUS7	0.018890
TNNI2	-0.018887
LOC100132167	-0.018883
PRKCDBP	0.018864
KRT23	-0.018863
SLITRK5	-0.018845
HOGA1	-0.018833
PCED1B	0.018823
LY6G6C	-0.018821
RNF217-AS1	-0.018813
AQP5	0.018806